Abstract:
A method for mesuring a scattering property and an absorption property in a scattering medium according to the present invention comprises: (a) a first step of letting pulsed measuring light having a predetermined wavelength enter a scattering medium; (b) a second step of performing time-resolved measurement of the measuring light having diffusively propagated in the scattering medium at light detection positions corresponding to a plurality of combinations, each comprised of a light incidence position on the scattering medium where the measuring light was let to enter the scattering medium in the first step and a light detection position on the scattering medium where the measuring light is detected, having different incidence-detection distances between the light incidence position and the light detection position; (c) a third step of calculating a plurality of mean optical pathlengths of the measuring light corresponding to the plurality of incidence-detection distances, based on results of the time-resolved measurement measured in the second step; and (d) a fourth step of calculating a scattering coefficient and an absorption coefficient in the scattering medium, based on a plurality of simultaneous relations consisting of calculation values of the plurality of mean optical pathlengths corresponding to the incidence-detection distances, calculated in the third step, and a theoretical equation of the mean optical pathlengths derived in correspondence to light diffusion properties comprising a scattering property and an absorption property in diffusive propagation paths in the scattering medium.
Abstract:
A device for measuring a scattering absorber comprises: a measuring module (1) having an irradiation probe (11) and detection probes (61, 71); and a measuring module (2) having an irradiation probe (21) and detection probes (81, 91). For a common light source for the irradiation probes (11, 21), i.e. a pulse light source (30), a light delay unit (22) is provided between the light source (30) and the irradiation probe (21) so tat a pulse light is irradiated sequentially from the irradiation probes (11, 21). A trigger circuit (50) designates the pulse light irradiation timing of the light source (30) and the light detection timing of signal processing circuits (62-92) in synchronism with the irradiation timing. Thus, it is possible to realize a device and a method for measuring a scattering absorber capable of suppressing crosstalk between channels with no spatial limitation.
Abstract:
An optical CT device (10) chiefly comprises a container (12) filled with optical interface material (20), a projector including a light source (22) and an optical switch (24) to project light into the container (12), a photodetector including a photodetector element (30) and a shutter (32) to detect the light through the container (12), and a processor/controller (14) for computing the spatial distribution of an absorption coefficient. The processor/controller (14) determines the spatial distribution of the quantity of feature concerning an optical characteristic of an object (200) for measurement based on the comparison between the light intensity signal from the detector (30) with the container (10) filled with the optical interface material (20) and such a signal from the detector (30) with the optical interface material (20) replaced in part by the object (200) for measurement.
Abstract:
An instrument comprises a measured portion holding device (3) composed by using a negative image of a portion (10) to be measured. Therefore the variation of the measured value due to the uneven distribution of the component in the portion (10) is reduced, and the variation of the measured value due to the variation of the optical path length of the portion (10) caused by the variation of the shape of the portion (10) and to the variation of the blood flow volume caused by the variation of the contact pressure is reduced. Biological information or measurement parameters are recorded in a recording medium (11) worn on the measured portion holding device (3) dedicatedly used for an individual subject. As a result, biological information on the individual subject is prevented from being mistaken, thus realizing reproducible measurement.
Abstract:
A breast measurement apparatus 1A includes a distance measurement unit 10 measuring a distance from a skin to a light absorption portion for a measurement region of a breast which is a normal region including no tumor or an object region including a tumor, a light measurement unit 15 measuring a hemoglobin amount in the measurement region by a light measurement method using measurement light of a predetermined wavelength, a correlation data storage unit 33 storing normal correlation data of the distance to the light absorption portion and a normal hemoglobin amount generated based on measurement results for normal regions, and an evaluation value calculation unit 35 calculating a property evaluation value of the tumor based on the normal hemoglobin amount, obtained from the normal correlation data and the distance to the light absorption portion in the object region, and an object hemoglobin amount in the object region. This realizes a breast measurement method and a measurement apparatus capable of improving measurement accuracy of a property of a tumor inside a breast.
Abstract:
A mammography device 1 is an apparatus for acquiring internal information of a breast B of an examinee A by radiating light to the breast B and detecting the diffused light, and includes a container 3 configured to surround the breast B and a plurality of optical fibers 11 attached to be directed inward in the container 3 and configured to perform radiation and detection of light. The container 3 has a base member 30 having an opening 30a, a plurality of annular members 40 continuously disposed to come in communication with the opening 30a, and a bottom member 50 disposed inside the annular member 40 spaced the farthest distance from the base member 30. The annular members 40 and the bottom member 50 are configured to relatively displace the adjacent annular member 40 on the side of the base member 30 or the base member 30 in a communication direction. Some of the plurality of optical fibers 11 is attached to the plurality of annular members 40.
Abstract:
The bioinstrumentation apparatus 10 includes a light irradiation unit irradiating a measurement region B with light, a light detection unit detecting diffused light from the measurement region, and a computing unit 14 generating a reconstructed image for the interior of the measurement region. The computing unit 14 calculates J coefficients w j set for every pixel of the reconstructed image and more than 0 and not more than 1 (where J is the number of pixels of the reconstructed image) and carries out successive approximation computation by the following iterative formula x j k + 1 = x j k + w j �¢ d j k (where k is an integer from 1 to N, N is the number of times of iterative computation, x j (k) is a pixel value of the jth pixel on the kth iterative computation, and d j (k) is an update amount of the jth pixel on the kth iterative computation) to generate the reconstructed image. Thereby, there are provided a bioinstrumentation apparatus and an image generating method capable of suppressing a difference in spatial resolution and noise characteristics depending on a position inside the measurement region to generate an image which is uniform to a greater extent.