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公开(公告)号:CA925508A
公开(公告)日:1973-05-01
申请号:CA92749
申请日:1970-09-10
Applicant: HOECHST AG
IPC: C07D237/14 , C07D213/64 , C07D215/22 , C07D237/30 , C07D239/34 , C07D239/72 , C07D241/18 , C07D277/20 , C07D277/34 , C07D277/68 , C07D295/04 , C07D295/067 , C07D295/185
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公开(公告)号:ZA706140B
公开(公告)日:1971-12-29
申请号:ZA706140
申请日:1970-09-09
Applicant: HOECHST AG
IPC: C07D237/14 , C07D213/64 , C07D215/22 , C07D237/30 , C07D239/34 , C07D239/72 , C07D241/18 , C07D277/20 , C07D277/34 , C07D277/68 , C07D295/04 , C07D295/067 , C07D295/185 , C07D
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公开(公告)号:SE302462B
公开(公告)日:1968-07-22
申请号:SE684965
申请日:1965-05-25
Applicant: HOECHST AG
IPC: C07D249/12 , C07D55/06
Abstract: The invention comprises compounds of the general formula (wherein R represents a phenyl group which may be substituted by at least one substituent selected from halogen atoms, the trifluoromethyl group and alkyl and alkoxy groups containing 1 to 4 carbon atoms, R1 represents an alkyl group containing 1 to 4 carbon atoms or an aralkyl group in which the alkylene residue contains 1 or 2 carbon atoms, R2 and R3 each represents an alkyl group containing 1 to 4 carbon atoms or a cycloalkyl group containing 5 to 7 carbon atoms, or together with the adjoining nitrogen atom are members of a ring system containing 4 or 5 carbon atoms and which may contain as a further hetero atom an oxygen, nitrogen or sulphur atom and/or at least one substituent, and A represents an alkylene group containing 2 to 4 carbon atoms) and physiologically tolerable acid addition salts thereof, pharmaceutical preparations containing them, and their preparation by standard methods from a compound of the formula or an appropriate 4-substituted derivative thereof. Starting materials in which R=phenyl, R1= methyl and the 4-substituent is -CH2CH2Br, -CH2CH2CN or -CH2CH(OC2H5)2 are prepared from (II, R=phenyl, R1=methyl. The compounds of the invention are sedatives, and may be administered orally or parenterally in the form of pharmaceutical preparations (e.g. tablets and dragees) containing them together with a carrier.
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公开(公告)号:SE302460B
公开(公告)日:1968-07-22
申请号:SE684765
申请日:1965-05-25
Applicant: HOECHST AG
IPC: C07D249/12 , C07D55/06
Abstract: The invention comprises compounds of the general formula (wherein R represents a phenyl group which may be substituted by at least one substituent selected from halogen atoms, the trifluoromethyl group and alkyl and alkoxy groups containing 1 to 4 carbon atoms, R1 represents an alkyl group containing 1 to 4 carbon atoms or an aralkyl group in which the alkylene residue contains 1 or 2 carbon atoms, R2 and R3 each represents an alkyl group containing 1 to 4 carbon atoms or a cycloalkyl group containing 5 to 7 carbon atoms, or together with the adjoining nitrogen atom are members of a ring system containing 4 or 5 carbon atoms and which may contain as a further hetero atom an oxygen, nitrogen or sulphur atom and/or at least one substituent, and A represents an alkylene group containing 2 to 4 carbon atoms) and physiologically tolerable acid addition salts thereof, pharmaceutical preparations containing them, and their preparation by standard methods from a compound of the formula or an appropriate 4-substituted derivative thereof. Starting materials in which R=phenyl, R1= methyl and the 4-substituent is -CH2CH2Br, -CH2CH2CN or -CH2CH(OC2H5)2 are prepared from (II, R=phenyl, R1=methyl. The compounds of the invention are sedatives, and may be administered orally or parenterally in the form of pharmaceutical preparations (e.g. tablets and dragees) containing them together with a carrier.
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公开(公告)号:SE302457B
公开(公告)日:1968-07-22
申请号:SE825462
申请日:1962-07-26
Applicant: HOECHST AG
IPC: C07D249/12 , C07D55/06
Abstract: The invention comprises compounds of the general formula (wherein R represents a phenyl group which may be substituted by at least one substituent selected from halogen atoms, the trifluoromethyl group and alkyl and alkoxy groups containing 1 to 4 carbon atoms, R1 represents an alkyl group containing 1 to 4 carbon atoms or an aralkyl group in which the alkylene residue contains 1 or 2 carbon atoms, R2 and R3 each represents an alkyl group containing 1 to 4 carbon atoms or a cycloalkyl group containing 5 to 7 carbon atoms, or together with the adjoining nitrogen atom are members of a ring system containing 4 or 5 carbon atoms and which may contain as a further hetero atom an oxygen, nitrogen or sulphur atom and/or at least one substituent, and A represents an alkylene group containing 2 to 4 carbon atoms) and physiologically tolerable acid addition salts thereof, pharmaceutical preparations containing them, and their preparation by standard methods from a compound of the formula or an appropriate 4-substituted derivative thereof. Starting materials in which R=phenyl, R1= methyl and the 4-substituent is -CH2CH2Br, -CH2CH2CN or -CH2CH(OC2H5)2 are prepared from (II, R=phenyl, R1=methyl. The compounds of the invention are sedatives, and may be administered orally or parenterally in the form of pharmaceutical preparations (e.g. tablets and dragees) containing them together with a carrier.
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公开(公告)号:AU6471280A
公开(公告)日:1981-06-04
申请号:AU6471280
申请日:1980-11-26
Applicant: HOECHST AG
IPC: G03B27/62 , G03G15/00 , B65H9/06 , B65H9/10 , B65H9/20 , B65H5/10 , B65H7/08 , B65H7/14 , B65H79/00
Abstract: The invention relates to a semi-automatic aligning and feeding device (1) for copiers, for the purpose of aligning an original (25) and feeding it from a feed table (17) to an object stage (5). Sensors (L1 to L5) are provided for scanning the original in various positions. Except for one sensor (L2), the sensors are located in or on the pivotable cover (3) of the device. The original, laid by hand onto the feed table (17), is picked up by a suction bar (11) which is equipped with spring suction heads (12, 12') and is, corresponding to its particular operating state, supplied either with vacuum or with compressed air and can be moved from a starting position into an end position and back again. In the end position, the spring suction heads are supplied with compressed air so that the original is laid down in precise alignment on the object stage.
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公开(公告)号:NO130685C
公开(公告)日:1975-01-22
申请号:NO17066667
申请日:1967-11-23
Applicant: HOECHST AG
Inventor: KUCH H , SCHMITT K , SEIDL G , HOFFMANN I
Abstract: 1,214,000. Benzothiazine derivatives. FARBWERKE HOECHST A.G. 27 Nov., 1967 [26 Nov., 1966], No. 53960/67. Heading C2C. Compounds of the general formula (R = H, alkyl, cycloalkyl, alkenyl, cycloalkenyl, aryl, aralkyl, lower dialkylaminoalkyl, or lower aminoalkyl in which the amino group has the formula A#N-, A representing an alkylene group that may be interrupted by O, S, methylimino or benzylimino; R 1 = H, halogen, OMe, CF 3 or NO 2 ; R 2,3 = alkyl, cycloalkyl, phenylalkyl or phenyl, in which the phenyl group or the phenyl residue of the phenylalkyl group may be substituted by one or more substituents selected from halogen, OMe, CF 3 and NO 2 ) and their acid addition salts are prepared by (a) reacting a compound of the formula (X = Cl, Br, OH, SH, alkoxy, alkylthio or alkanoyloxy) or a salt thereof with (R values identical or different) or R.NCS or a compound capable of forming such an isothiocyanate, if necessary or desired in the presence of an acid and/or a dehydrating agent, (b) reacting a compound of the formula or a functional derivative thereof with an inorganic sulphide or, if X = SH or alkylthio, with a dehydrating agent, if necessary or desired in the presence of an acid, (c) reacting a compound of the formula (R 4 = Cl, Br, amino, SH or alkylthio) with R 1 NH 2 (R 1 = R other than H) or a salt thereof, or (d) reducing with a complex metal hydride or saponifying a compound of the formula (R 11 = alkyl, alkenyl, aryl, aralkyl, haloalkyl, lower dialkylaminoalkyl, or lower aminoalkyl in which the amino group has the formula A#N-), the compound being reacted, before or after reduction of the acyl group, with a dialkylamine or an appropriate cyclic amine in cases where R 11 = haloalkyl, optionally followed in each case by salt formation. The, lower dialkylaminoalkyl and aminoalkyl groups (excluding any interrupting methylimino or benzylimino group in the latter case) contain up to ten carbon atoms. The isolation of intermediate thiourea derivatives in process (a) is described. The above compounds possess a depressive effect on the central nervous system, a stimulating, tranquillizing and narcosis-prolonging activity and analgesic and spasmolytic activity. They may be administered in the form of pharmaceutical preparations containing them in association with a carrier.
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公开(公告)号:ZA7205836B
公开(公告)日:1973-06-27
申请号:ZA7205836
申请日:1972-08-24
Applicant: HOECHST AG
Inventor: RUSCHIG H , SEIDL G , SELIGER H , SCHMITT K , ALPERMANN H
IPC: C07D209/44 , C07D
CPC classification number: C07D209/44
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公开(公告)号:ZA7204294B
公开(公告)日:1973-03-28
申请号:ZA7204294
申请日:1972-06-22
Applicant: HOECHST AG
Inventor: SCHMITT K , HOFFMANN I
IPC: C07D295/13 , C07D
CPC classification number: C07D295/13 , Y10S514/906
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公开(公告)号:NO125723B
公开(公告)日:1972-10-23
申请号:NO90568
申请日:1968-03-08
Applicant: HOECHST AG
Inventor: RUSCHIG H , HAERTFELDER G , SCHMITT K , LESSENICH H
IPC: A61K31/135 , C07C91/04 , C07C93/14
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