公开(公告)号：DE59308021D1

公开(公告)日：1998-02-26

申请号：DE59308021

申请日：1993-08-17

Applicant: HOECHST AG

Inventor： ZOLLER GERHARD DR ,  JABLONKA BERND DR ,  JUST MELITTA DR ,  KLINGLER OTMAR DR ,  BREIPOHL GERHARD DR ,  KNOLLE JOCHEN DR ,  KOENIG WOLFGANG DR

IPC: A61K31/415 ,  A61K31/4166 ,  A61K38/00 ,  A61K38/05 ,  A61K38/07 ,  A61P7/02 ,  A61P19/10 ,  A61P35/00 ,  A61P35/04 ,  C07D233/72 ,  C07D233/76 ,  C07D233/78 ,  C07D233/86 ,  C07K1/113 ,  C07K5/02 ,  C07K5/06 ,  C07K5/072 ,  C07K5/10 ,  C07K5/117

Abstract: The present invention relates to compounds of the general formula I in which R, R to R and r, Y, Z and W are defined as stated in the description, to processes for their preparation and to their use as inhibitors of platelet aggregation, of metastasis of carcinoma cells, and of osteoclast binding to bone surfaces.

公开(公告)号：ES2081000T3

公开(公告)日：1996-02-16

申请号：ES92113086

申请日：1992-07-31

Applicant: HOECHST AG

Inventor： KONIG WOLFGANG DR ,  ZOLLER GERHARD DR ,  JUST MELITTTA DR ,  JABLONKA BERND DR

IPC: A61K31/415 ,  A61K31/4166 ,  A61K38/00 ,  A61K38/04 ,  A61K38/05 ,  A61K38/06 ,  A61P7/02 ,  A61P9/10 ,  A61P19/10 ,  A61P35/00 ,  A61P43/00 ,  C07D233/76 ,  C07D233/96 ,  C07K1/02 ,  C07K5/02 ,  C07K5/023 ,  C07K5/06 ,  C07K5/062 ,  C07K5/072 ,  C07K5/078 ,  C07K5/08 ,  C07K5/083 ,  C07K5/09 ,  C07K5/097 ,  C07K5/10 ,  C07K5/11 ,  C07K5/117

Abstract: The present invention relates to hydantoin derivatives of the general formula I in which Y and R to R are defined as indicated in claim 1, process for the preparation thereof and the use thereof for inhibiting platelet aggregation.