公开(公告)号：NO972707D0

公开(公告)日：1997-06-12

申请号：NO972707

申请日：1997-06-12

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94

Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.

公开(公告)号：HU9701032A2

公开(公告)日：1998-08-28

申请号：HU9701032

申请日：1997-06-11

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94

Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.

公开(公告)号：CZ9701795A3

公开(公告)日：1998-03-18

申请号：CZ179597

申请日：1997-06-11

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN LUC ,  NOTHACKER HANS PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94

CPC classification number: G01N33/9486 ,  G01N33/566 ,  G01N2500/00

公开(公告)号：ZA9705077B

公开(公告)日：1997-12-15

申请号：ZA9705077

申请日：1997-06-09

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHELD RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94 ,  G01N ,  A61K

CPC classification number: G01N33/9486 ,  G01N33/566 ,  G01N2500/00

公开(公告)号：NO972707A

公开(公告)日：1997-12-15

申请号：NO972707

申请日：1997-06-12

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94 ,  G01N33/68

CPC classification number: G01N33/9486 ,  G01N33/566 ,  G01N2500/00

公开(公告)号：AU719519B2

公开(公告)日：2000-05-11

申请号：AU2485397

申请日：1997-06-12

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94 ,  G01N33/68

Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.

公开(公告)号：NZ328033A

公开(公告)日：1998-11-25

申请号：NZ32803397

申请日：1997-06-06

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94 ,  G01N33/68 ,  C07K14/435

Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.

公开(公告)号：CZ179597A3

公开(公告)日：1998-03-18

申请号：CZ179597

申请日：1997-06-11

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN LUC ,  NOTHACKER HANS PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94

Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.

公开(公告)号：HU9701032D0

公开(公告)日：1997-07-28

申请号：HU9701032

申请日：1997-06-11

Applicant: HOFFMANN LA ROCHE

Inventor： CIVELLI OLIVIER ,  MARTIN JAMES RICHARD ,  MONSMA FREDERICK ,  MOREAU JEAN-LUC ,  NOTHACKER HANS-PETER ,  REINSCHEID RAINER

IPC: G01N33/53 ,  A61K38/00 ,  A61K38/10 ,  A61P25/08 ,  A61P25/20 ,  A61P25/26 ,  G01N33/15 ,  G01N33/566 ,  G01N33/94

Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.