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公开(公告)号:ZA9705077B
公开(公告)日:1997-12-15
申请号:ZA9705077
申请日:1997-06-09
Applicant: HOFFMANN LA ROCHE
Inventor: CIVELLI OLIVIER , MARTIN JAMES RICHARD , MONSMA FREDERICK , MOREAU JEAN-LUC , NOTHACKER HANS-PETER , REINSCHELD RAINER
IPC: G01N33/53 , A61K38/00 , A61K38/10 , A61P25/08 , A61P25/20 , A61P25/26 , G01N33/15 , G01N33/566 , G01N33/94 , G01N , A61K
CPC classification number: G01N33/9486 , G01N33/566 , G01N2500/00
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公开(公告)号:ZA975077B
公开(公告)日:1997-12-15
申请号:ZA975077
申请日:1997-06-09
Applicant: HOFFMANN LA ROCHE
Inventor: CIVELLI OLIVIER , MARTIN JAMES RICHARD , MONSMA FREDERICK , MOREAU JEAN-LUC , NOTHACKER HANS-PETER , REINSCHELD RAINER
IPC: G01N33/53 , A61K38/00 , A61K38/10 , A61P25/08 , A61P25/20 , A61P25/26 , G01N33/15 , G01N33/566 , G01N33/94 , G01N , A61K
Abstract: The present invention relates to a method of screening for a therapeutically useful compound which comprises testing an LC132 receptor agonist in a screening assay for psychiatric and/or neurological disorders. More particularly, the screening method is based on contacting an LC132 receptor with an agent suspected of being an agonist of the LC132 receptor function, followed by the detection of the binding and/or the agonist activity of the compound and then testing of an agent with LC132 agonist activity in an antiepileptic, anticonvulsant or anxiolytic screening assay.
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