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公开(公告)号：EP3839636A1
公开(公告)日：2021-06-23
申请号：EP19218700.3
申请日：2019-12-20
Applicant: Imec VZW
Inventor： STAHL, Richard , YURT, Abdulkadir , LIN, Ziduo , VANMEERBEECK, Geert , LAMBRECHTS, Andy
Abstract: A device (1) for detecting particles (2) in air; said device (1) comprising:
a flow channel (30), wherein the flow channel (30) is configured to allow a flow of air (12) comprising particles (2) through the flow channel (30);
a light source (40) configured to illuminate the particles (2) in the flow of air (12), such that an interference pattern is formed by interference between light being scattered by the particles (2) and non-scattered light from the light source (40);
an image sensor (50) configured to detect incident light, the image sensor (50) being configured to detect the interference pattern, and wherein the image sensor (50) is configured to acquire a time-sequence of image frames, each image frame comprising a plurality of pixels, each pixel representing a detected intensity of light; and
a frame processor (70) configured to filter information in the time-sequence of image frames, wherein said filtering comprises:
identifying pixels of interest in the time-sequence of image frames, said pixels of interest picturing an interference pattern potentially representing a particle (2) in the flow of air (12), and
outputting said identified pixels of interest for performing digital holographic reconstruction on the identified pixels of interest.-
公开(公告)号：EP3339963B1
公开(公告)日：2020-08-12
申请号：EP16205862.2
申请日：2016-12-21
Applicant: IMEC vzw
Inventor： YURT, Abdulkadir , VANMEERBEECK, Geert , STAHL, Richard , LIN, Ziduo
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公开(公告)号：EP3552060A1
公开(公告)日：2019-10-16
申请号：EP17825408.2
申请日：2017-12-08
Applicant: IMEC VZW
Inventor： LIN, Ziduo , YURT, Abdulkadir , STAHL, Richard , VANMEERBEECK, Geert
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公开(公告)号：EP3254147A1
公开(公告)日：2017-12-13
申请号：EP16703513.8
申请日：2016-02-04
Applicant: IMEC vzw
Inventor： STAHL, Richard , CLAES, Tom , ROTTENBERG, Xavier , VANMEERBEECK, Geert , LAMBRECHTS, Andy
CPC classification number: G03H1/0465 , G01N15/1434 , G01N15/147 , G01N15/1484 , G01N2015/1454 , G02B6/122 , G02B21/0008 , G02B27/0087 , G02B2006/12061 , G03H1/0443 , G03H2001/0447 , G03H2222/34 , G03H2222/35 , G03H2222/53 , H04N5/2256 , H04N5/374
Abstract: Embodiments described herein relate to a large area lens-free imaging device. One example is a lens-free device for imaging one or more objects. The lens-free device includes a light source positioned for illuminating at least one object. The lens-free device also includes a detector positioned for recording interference patterns of the illuminated at least one object. The light source includes a plurality of light emitters that are positioned and configured to create a controlled light wavefront for performing lens-free imaging.
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公开(公告)号：EP3126818B1
公开(公告)日：2018-12-05
申请号：EP15713796.9
申请日：2015-04-03
Applicant: IMEC vzw
Inventor： REUMERS, Veerle , BRAEKEN, Dries , VANMEERBEECK, Geert , STAHL, Richard , LAMBRECHTS, Andy
IPC: G01N21/45 , G01N21/47 , G01N33/50 , G01N21/17 , G03H1/26 , G03H1/00 , G03H1/04 , G01N15/14 , G01N15/10 , G01N15/00
CPC classification number: G01N15/1031 , G01N15/1434 , G01N15/1468 , G01N21/1717 , G01N21/45 , G01N21/453 , G01N21/4788 , G01N33/5044 , G01N2015/0065 , G01N2015/1006 , G01N2015/1454 , G01N2021/1721 , G01N2021/1738 , G01N2021/1765 , G01N2201/06113 , G01N2201/062 , G01N2500/10 , G03H1/0005 , G03H1/0402 , G03H1/0443 , G03H1/0465 , G03H2001/0033 , G03H2001/005 , G03H2001/0447 , G03H2001/0469 , G03H2001/0471 , G03H2222/22 , G03H2226/11
Abstract: The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells.
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Patent Agency Ranking
公开(公告)号：EP3382467A1
公开(公告)日：2018-10-03
申请号：EP18163359.5
申请日：2018-03-22
Applicant: IMEC vzw
Inventor： LIN, Ziduo , STAHL, Richard , YURT, Abdulkadir
CPC classification number: G03H1/02 , G02B27/0977 , G02B27/22 , G03H1/0244 , G03H1/0443 , G03H1/0465 , G03H2001/0212 , G03H2001/0447 , G03H2001/045 , G03H2001/0454 , G03H2001/2655 , G03H2001/266 , G03H2222/13 , G03H2222/34 , G03H2222/35 , G03H2223/23 , G03H2226/11
Abstract: A device in, and system for, holographic imaging comprising: at least two light sources (102, 104, 106; 202, 204; 302, 304; 402, 404), wherein each of the at least two light sources is arranged to output light of a unique wavelength; and at least one holographic optical element (110; 208; 308; 410, 412, 414), wherein the at least two light sources and the at least one holographic optical element are arranged in relation to each other such that light from the at least two light sources incident on the at least one holographic optical element is diffractively diverted by the at least one holographic optical element to form wavefronts of similar and registered shape onto an image sensor (114, 210, 312).
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公开(公告)号：EP3339963A1
公开(公告)日：2018-06-27
申请号：EP16205862.2
申请日：2016-12-21
Applicant: IMEC vzw
Inventor： YURT, Abdulkadir , VANMEERBEECK, Geert , STAHL, Richard , LIN, Ziduo
Abstract: An apparatus for in-line holographic imaging is provided. The apparatus (100) comprises at least a first light source (102) and a second light source (104) arranged for illuminating an object (108) arranged in the apparatus (100) with a light beam; an image sensor (110) being arranged to detect at least a first and a second interference pattern, wherein the first interference pattern is formed when the object (108) is illuminated by the first light source (102) and the second interference pattern is formed when the object (108) is illuminated by the second light source (104), wherein the first and second interference patterns are formed by diffracted light, being scattered by the object (108), and undiffracted light of the light beam; wherein the at least first and second light sources (102, 104) are arranged at different angles in relation to the object (108), and possibly illuminate the object (108) using different wavelengths.
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公开(公告)号：EP3241047A1
公开(公告)日：2017-11-08
申请号：EP15823605.9
申请日：2015-12-28
Applicant: IMEC vzw
Inventor： VERCRUYSSE, Dries , VAN DORPE, Pol , ROTTENBERG, Xavier , CLAES, Tom , STAHL, Richard
CPC classification number: G02B6/34 , G01N15/1436 , G01N15/1484 , G02B6/12 , G02B2006/12107 , G03H1/0443 , G03H2001/0447
Abstract: The invention relates to an imaging device (1) comprising a photonic integrated circuit (2). This photonic integrated circuit comprises an integrated waveguide (4) for guiding a light signal (5), a light coupler (8) optically coupled to the integrated waveguide (4) and adapted for directing the light signal (5) out of the plane of the waveguide (4) as a light beam (9), and at least one imaging detector (11) positioned for imaging an object (12) illuminated by the light beam (9). The invention also relates to a corresponding method for imaging.
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公开(公告)号：EP3839637A1
公开(公告)日：2021-06-23
申请号：EP19218967.8
申请日：2019-12-20
Applicant: Imec VZW , Katholieke Universiteit Leuven, K.U.Leuven R&D
Inventor： LUO, Zhenxiang , BRAEKEN, Dries , LAGAE, Liesbet , STAHL, Richard , YURT, Abdulkadir
Abstract: A method for three-dimensional imaging of a sample (302) comprises: receiving (102) interference patterns (208) acquired using light-detecting elements (212), wherein each interference pattern (208) is formed by scattered light from the sample (302) and non-scattered light from a light source (206; 306), wherein the interference patterns (208) are acquired using different angles between the sample (302) and the light source (206; 306); performing digital holographic reconstruction by applying an iterative algorithm to change a three-dimensional scattering potential, i.e. amplitude, of the sample (302) to improve a difference between the received interference patterns (208) and predicted interference patterns based on the three-dimensional scattering potential; wherein the iterative algorithm reduces a sum of a data fidelity term and a non-differentiable regularization term and wherein the iterative algorithm includes a forward-backward splitting method alternating between forward gradient descent (108) on the data fidelity term and backward gradient descent (110) on the regularization term.
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公开(公告)号：EP3839478A1
公开(公告)日：2021-06-23
申请号：EP19218689.8
申请日：2019-12-20
Applicant: Imec VZW
Inventor： VANMEERBEECK, Geert , LIN, Ziduo , YURT, Abdulkadir , STAHL, Richard
Abstract: The inventive concept relates to a device for detecting particles in air, said device comprising a receiver for receiving a flow of air comprising particles, a sample carrier, and a particle capturing arrangement. The particle capturing arrangement is configured to separate the particles from the flow of air for and to collect a set of particles on a surface of the sample carrier. The device further comprises a light source configured to illuminate the particles on the sample carrier, such that an interference pattern is formed by interference between light being scattered by the particles and non-scattered light from the light source. The device further comprises an image sensor configured to detect the interference pattern. The device further comprises a cleaner configured for cleaning the surface of the sample carrier for enabling re-use of the surface for collection of a subsequent set of particles.
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