公开(公告)号：AU2010202162B2

公开(公告)日：2012-09-06

申请号：AU2010202162

申请日：2010-05-27

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: C:\NRPotbhDCC\AXL\298L426_I.DOC-27M/2010 Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during 5 measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a 10 temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature. ,-26 ,/24 33 82 0 1 6 12p18 Fig. 1 4093.a 'A, I Li V~--A 1 2 3 4 6 6 7 8 0 10 11 12 13 14 15 16 17 '18 10 V 21 TomperawLre Iiodex Fig. 2

公开(公告)号：AU2010202159A1

公开(公告)日：2010-06-24

申请号：AU2010202159

申请日：2010-05-27

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: A method for controlling one or more parameters of a flow cytometer type measurement system, is disclosed. The comprises the following steps - measuring a time in which a microsphere (10) travels from a first detection window of the flow cytometer type measurement system to a second detection window of the measurement system; and - altering an applied pressure of the measurement system such that the time is substantially constant.

公开(公告)号：CA2767032A1

公开(公告)日：2005-02-24

申请号：CA2767032

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/10 ,  G01N15/14

Abstract: Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.

公开(公告)号：CA2535333C

公开(公告)日：2015-04-21

申请号：CA2535333

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.

公开(公告)号：AU2010202161B2

公开(公告)日：2012-02-09

申请号：AU2010202161

申请日：2010-05-27

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: C:\NRPortbr\DCC\AXL\298067_ .DOC-27A5/2010 Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during 5 measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a 10 temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature. ,-26 28-> 34 32->3 \ \/ ~2 0 16 Fig. 1 3072~ , *:27 - , ~ 3512 V . __ _ _ _ 1 2 3 41 6 G 7 9 0 10 11 12 13 14 16 16 17 18 10 Z) 21 Tonlpara~ire Index Fig2

公开(公告)号：AU2010202160A1

公开(公告)日：2010-06-17

申请号：AU2010202160

申请日：2010-05-27

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: A method for controlling one or more parameters of a flow cytometer type measurement system, is disclosed. The comprises the following steps - measuring a time in which a microsphere (10) travels from a first detection window of the flow cytometer type measurement system to a second detection window of the measurement system; and - altering an applied pressure of the measurement system such that the time is substantially constant.

公开(公告)号：CA2767108C

公开(公告)日：2013-10-22

申请号：CA2767108

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/10 ,  G01N15/14

Abstract: Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.

公开(公告)号：CA2767032C

公开(公告)日：2013-02-19

申请号：CA2767032

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/10 ,  G01N15/14

Abstract: Various methods for controlling one or more parameters of a flow cytometer type measurement system are provided. One embodiment includes monitoring parameter(s) of the measurement system during measurements of sample microspheres. The method also includes altering the parameter(s) in real time based on the monitoring. Another method includes monitoring a temperature proximate to the measurement system. One such method includes altering a bias voltage of an avalanche photo diode in response to the temperature using empirically derived data. A different such method includes altering output signals of a photomultiplier tube in response to the temperature using a characteristic curve. Some methods include monitoring a temperature of a fluid, in which sample microspheres are disposed, that will flow through the flow cytometer type measurement system. This method also includes determining a velocity of the sample microspheres in the measurement system from a viscosity of the fluid at the temperature.

公开(公告)号：AU2010202162A1

公开(公告)日：2010-06-17

申请号：AU2010202162

申请日：2010-05-27

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/14

Abstract: A method for controlling one or more parameters of a flow cytometer type measurement system, is disclosed. The comprises the following steps - measuring a time in which a microsphere (10) travels from a first detection window of the flow cytometer type measurement system to a second detection window of the measurement system; and - altering an applied pressure of the measurement system such that the time is substantially constant.

公开(公告)号：CA2767108A1

公开(公告)日：2005-02-24

申请号：CA2767108

申请日：2004-08-13

Applicant: LUMINEX CORP

Inventor： ROTH WAYNE D ,  MOORE DOUGLAS E

IPC: G01N15/10 ,  G01N15/14

Abstract: A method for controlling one or more parameters of a flow cytometer type measurement system, is disclosed. The comprises the following steps - measuring a time in which a microsphere (10) travels from a first detection window of the flow cytometer type measurement system to a second detection window of the measurement system; and - altering an applied pressure of the measurement system such that the time is substantially constant.