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    Composition and method for dyeing keratinous fibers
    11.
    发明授权
    Composition and method for dyeing keratinous fibers 失效
    染色角质纤维的组合物和方法

    公开(公告)号：US3905761A

    公开(公告)日：1975-09-16

    申请号：US30199872

    申请日：1972-10-30

    Applicant: OREAL

    Inventor： KALOPISSIS GREGOIRE ,  BUGAUT ANDREE ,  ESTRADIER FRANCOISE

    IPC: A61K8/41 ,  A61Q5/10 ,  A61K7/13

    CPC classification number: A61Q5/10 ,  A61K8/413 ,  Y10S424/02

    Abstract: Diphenylamines having the formula

    WHEREIN: Y represents a member selected from the group consisting of a hydroxy and amino, R1 and R3, each independently, represent a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, a ureido residue, and -NHCOR wherein R is lower alkyl, R2 represents a member selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, a ureido residue, -NHCOR wherein R is lower alkyl, and -NHR8 wherein R8 represents a member selected from the group consisting of hydrogen, lower alkyl, lower hydroxyalkyl and carbamylmethyl, with the proviso that when R2 is -NHR8, R3 is not hydrogen R4, R5, R6, and R7 each independently represent a member selected from the group consisting of hydrogen, halogen, lower alkyl and lower alkoxy, with the proviso that when Y is hydroxy, R2 is not hydrogen, halogen, lower alkyl or lower alkoxy, and that when Y is amino, at least two of R1, R2 and R3 are other than a hydrogen and R2 is not hydrogen when R4, R5, R6 and R7 are all hydrogen and the acid addition salts of said diphenylamines.

    Abstract translation: 具有式WHEREIN：Y的二苯胺表示选自羟基和氨基的成员，R 1和R 3各自独立地表示选自氢，卤素，低级烷基，低级烷氧基，脲基残基的成员 和-NHCOR，其中R是低级烷基，R 2表示选自氢，卤素，低级烷基，低级烷氧基，脲基残基，-NHCOR，其中R是低级烷基，-NHR 8，其中R8代表成员 选自氢，低级烷基，低级羟基烷基和氨基甲酰甲基，条件是当R 2为-NHR 8时，R 3不为氢，R 4，R 6和R 7各自独立地表示选自氢， ，卤素，低级烷基和低级烷氧基，条件是当Y为羟基时，R 2不为氢，卤素，低级烷基或低级烷氧基，当Y为氨基时，R 1，R 2和R 3中的至少两个为 氢和 当R4，R5，R6和R7都是氢时，R2不是氢，也就是所说的二苯胺的酸加成盐。

    Indamines for dyeing keratinic fibers
    12.
    发明授权
    Indamines for dyeing keratinic fibers 失效
    用于染色可卡因纤维的痕迹

    公开(公告)号：US3876368A

    公开(公告)日：1975-04-08

    申请号：US38761373

    申请日：1973-08-13

    Applicant: OREAL

    Inventor： KALOPISSIS GREGOIRE ,  BUGAUT ANDREE ,  ESTRADIER FRANCOISE

    IPC: A61K8/41 ,  A61Q5/10 ,  H01K1/12 ,  D06P3/04

    CPC classification number: A61K8/413 ,  A61Q5/10 ,  Y10S424/01 ,  Y10S424/02

    Abstract: Imdamine having the formula

    Wherein R and R'' each independently represent a member selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms, lower alkoxy having 1-4 carbon atoms, amino, acylamino wherein the acyl moiety has 1 to 4 carbon atoms and hydroxy, with the proviso that one, but not both of R and R'' is said amino, acylamino or hydroxy; R.sub.1 and R.sub.2 each independently represent a member selected from the group consisting of lower alkyl having 1-4 carbon atoms and lower alkyl having 1-4 carbon atoms and substituted with a member selected from the group consisting of hydroxy, acylamino wherein the acyl moiety has 1 to 4 carbon atoms, carbamyl, piperidino, benzoylamino and alkylsulfonamido wherein the alkyl moiety has 1 to 4 carbon atoms; R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 each independently represent a member selected from the group consisting of hydrogen, lower alkyl having 1-4 carbon atoms and lower alkoxy having 1-4 carbon atoms, and the salts formed by these indamines with organic or inorganic acids, in particular, their acetates, hydrochlorides, hydrobromides, persulfates, perchlorates and the double zinc salts of these compounds, which can, of course, be in a tautomeric form of that represented by formula (I), are usefully employed for dyeing keratinous fibers, and, in particular, human hair.

    COMPOSITIONS DESTINEES A ETRE UTILISEES POUR FREINER LA CHUTE DES CHEVEUX ET POUR INDUIRE ET STIMULER LEUR CROISSANCE, CONTENANT DES OXADIAZOLOPYRIMIDINES
    15.
    发明专利
    COMPOSITIONS DESTINEES A ETRE UTILISEES POUR FREINER LA CHUTE DES CHEVEUX ET POUR INDUIRE ET STIMULER LEUR CROISSANCE, CONTENANT DES OXADIAZOLOPYRIMIDINES 未知

    公开(公告)号：CA2285886A1

    公开(公告)日：1991-03-01

    申请号：CA2285886

    申请日：1990-08-28

    Applicant: OREAL

    Inventor： GAETANI QUINTINO ,  DUFETEL DIDIER ,  HOCQUAUX MICHEL ,  ESTRADIER FRANCOISE

    IPC: A61K31/505 ,  A61K31/54 ,  A61K31/55 ,  C07D498/04 ,  A61K7/06

    Abstract: L'invention concerne une composition pharmaceutique ou cosmétique, destinée à être utilisée en application topique pour freiner la chute des cheveux et pour induire et stimuler leur croissance. La composition selon l'invention est caractérisée par le fait qu'elle contient dans un milieu physiologiquement acceptable, au moins un composé répondant à la formule générale: (voir formule III) dans laquelle: R désigne un atome d'hydrogène, un radical alkyle, saturé et linéaire, en C1-C8 ou forme avec le cycle pyrimidine, un cycle hydrocarboné de formule: (voir formule ci-haut) 63 où n est égal à 1, 2 ou 3; X désigne (i) un atome d'hydrogène; (ii)un groupement de formule: dans laquelle R1 et R2, identiques ou différents, désignent un atome d'hydrogène, un groupe alkyle saturé en C1-C12, linéaire ou ramifié, non substitué ou substitué par un atome d'halogène ou un radical trifluorométhyle, un groupe alcényle linéaire en C2-C12, un groupe cycloalkyle en C3-C10, un groupe aralkyle en C7-C12 ou un groupement aryle répondant à la formule: dans laquelle R9 et R10, identiques ou différents, désignent un atome d'hydrogène ou d'halogène, ou un groupe alkyle en C1-C4, hydroxyle ou alcoxy en C1-C4; ou bien R1 et R2 forment avec l'atome d'azote auquel ils sont reliés, un hétérocycle saturé ou insaturé, choisi parmi les groupe aziridino, azétidino, pyrrolidino, pipéridino, hexaméthylèneimino, heptaméthylèneimino octaméthylèneimino, tétrahydropyridino, dihydropyridino, pyrrole, pyrrazole, imidazole et thiomorpholino; (iii) un groupement -OR3, dans lequel R3 désigne un radical alkyle saturé en C1-C12, linéaire ou ramifié, non substitué ou substitué par un atome d'halogène ou un radical trifluorométhyle, un radical alcényle linéaire en C2-C12, un radical cycloalkyle en 64 C3-C10, un radical aralkyle en C7-C12, un radical phényle éventuellement substitué par un ou deux groupement, qui, indépendamment l'un de l'autre, désignent un atome d'halogène, un radical alkyle en C1-C6, un radical alcoxy en C1-C6, ou un radical trifluorométhyle; ou (iv) un groupement -SR4, dans lequel R4 a la même signification que R3; ou l'un de ses sels d'addition d'acides physiologiquement acceptables.

    19.
    发明专利
    未知

    公开(公告)号：CH597860A5

    公开(公告)日：1978-04-14

    申请号：CH1648774

    申请日：1974-12-11

    Applicant: OREAL

    Inventor： KALOPISSIS GREGOIRE ,  BUGAUT-NEE-ORMANCEY ANDREE ,  ESTRADIER FRANCOISE

    IPC: A61K8/41 ,  A61Q5/10 ,  C09B53/02 ,  A61K7/13

    Abstract: New dyestuffs are described for keratinic fibers which produce particularly luminous shades without the need for an oxidizing agent. These dyestuffs have the formula: (I) or a tautomeric form thereof wherein each of R1 and R4, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, acylamino and ureido; each of R2 and R3, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, amino, N-alkylamino, N-(hydroxyalkyl)-amino, N-(carbamyl-alkyl)-amino, acylamino and ureido, each of said alkyls containing 1 to 6 carbon atoms; each of R5 and R6, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl containing 1 to 6 carbon atoms and alkoxy containing 1 to 6 carbon atoms, with the proviso that when R5 and R6 are both other than hydrogen at least one is in a meta-position relative to the NHR7 group; and R7 represents a member selected from alkyl, hydroxyalkyl, acylaminoalkyl, mesylaminoalkyl, carbamylalkyl, aminoalkyl, piperidinoalkyl and morpholinoalkyl, each of said alkyls containing 1 to 6 carbon atoms.

    INDOANILINES N-MONOSUBSTITUEES EN POSITION 4S UUTILISABLES POU R LA TEINTURE DES FIBRES TINIQUES, EN PARTICULIER DES CHEVEUX HUMAINS
    20.
    发明专利
    INDOANILINES N-MONOSUBSTITUEES EN POSITION 4S UUTILISABLES POU R LA TEINTURE DES FIBRES TINIQUES, EN PARTICULIER DES CHEVEUX HUMAINS 未知

    公开(公告)号：CA1019739A

    公开(公告)日：1977-10-25

    申请号：CA215774

    申请日：1974-12-11

    Applicant: OREAL

    Inventor： KALOPISSIS GREGOIRE ,  BUGAUT ANDREE ,  ESTRADIER FRANCOISE

    IPC: A61K8/41 ,  A61Q5/10 ,  C09B53/02

    Abstract: New dyestuffs are described for keratinic fibers which produce particularly luminous shades without the need for an oxidizing agent. These dyestuffs have the formula: (I) or a tautomeric form thereof wherein each of R1 and R4, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, acylamino and ureido; each of R2 and R3, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl having 1 to 6 carbon atoms, alkoxy having 1 to 6 carbon atoms, amino, N-alkylamino, N-(hydroxyalkyl)-amino, N-(carbamyl-alkyl)-amino, acylamino and ureido, each of said alkyls containing 1 to 6 carbon atoms; each of R5 and R6, which may be identical or different, represents a member selected from hydrogen, halogen, alkyl containing 1 to 6 carbon atoms and alkoxy containing 1 to 6 carbon atoms, with the proviso that when R5 and R6 are both other than hydrogen at least one is in a meta-position relative to the NHR7 group; and R7 represents a member selected from alkyl, hydroxyalkyl, acylaminoalkyl, mesylaminoalkyl, carbamylalkyl, aminoalkyl, piperidinoalkyl and morpholinoalkyl, each of said alkyls containing 1 to 6 carbon atoms.

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