公开(公告)号：SI3386511T1

公开(公告)日：2021-09-30

申请号：SI201631243

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/00 ,  A61K31/00 ,  C07D237/00 ,  C07D401/00 ,  C07D405/00 ,  C07D413/00 ,  C07D417/00 ,  C07D471/00 ,  C07D487/00

公开(公告)号：AU2020201380B2

公开(公告)日：2020-10-08

申请号：AU2020201380

申请日：2020-02-25

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D405/12 ,  A61K31/506 ,  A61P25/00

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. N-N (I) In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：AU2020201380A1

公开(公告)日：2020-03-12

申请号：AU2020201380

申请日：2020-02-25

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D405/12 ,  A61K31/506 ,  A61P25/00

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. N-N (I) In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：HUE055031T2

公开(公告)日：2021-10-28

申请号：HUE16874024

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/12 ,  C07D237/20 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/10 ,  C07D487/10

公开(公告)号：DK3386511T3

公开(公告)日：2021-07-05

申请号：DK16874024

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D403/12 ,  A61K31/501 ,  A61K31/506 ,  A61K31/517 ,  C07D237/20 ,  C07D401/14 ,  C07D403/10 ,  C07D405/12 ,  C07D413/14 ,  C07D417/12 ,  C07D417/14 ,  C07D471/10 ,  C07D487/10

公开(公告)号：NZ743147A

公开(公告)日：2021-03-26

申请号：NZ74314716

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： MOON YOUNG-CHOON ,  BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  SYDORENKO NADIYA

IPC: A61K31/506 ,  A61P25/00 ,  C07D405/12

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (Ia), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington’s disease.

公开(公告)号：AU2016366694C1

公开(公告)日：2021-03-25

申请号：AU2016366694

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D405/12 ,  A61K31/506 ,  A61P25/00

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.

公开(公告)号：CA3067592A1

公开(公告)日：2019-01-03

申请号：CA3067592

申请日：2018-06-27

Applicant: PTC THERAPEUTICS INC

Inventor： BHATTACHARYYA ANURADHA ,  JANI MINAKSHI

IPC: A61K31/519 ,  A61K31/551 ,  A61P25/14

Abstract: The present description relates to a method or use of a compound for treating or ameliorating HD (Huntington's Disease) in a subject in need thereof comprising administering to the subject an effective amount of a compound of Formula (I): or a form thereof, wherein R1, R2, Ra, Rb and Rc are as defined herein. In particular, the present description relates to a method of use of a compound of Formula (I) or a form or composition thereof for treating or ameliorating HD in a subject in need thereof comprising, administering an effective amount of the compound or a form or composition thereof to the subject.

公开(公告)号：CA3119019A1

公开(公告)日：2017-06-15

申请号：CA3119019

申请日：2016-12-11

Applicant: PTC THERAPEUTICS INC

Inventor： BABU SURESH ,  BHATTACHARYYA ANURADHA ,  HWANG SEONGWOO ,  JANI MINAKSHI ,  MOON YOUNG-CHOON ,  SYDORENKO NADIYA

IPC: C07D401/14 ,  A61K31/501 ,  A61P25/14 ,  C07D401/12 ,  C07D405/14 ,  C07D409/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04 ,  C07D471/08 ,  C07D471/10 ,  C07D487/04 ,  C07D487/10

Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.