-
公开(公告)号：FI3814357T3
公开(公告)日：2024-07-26
申请号：FI19736566
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC , PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：HUE068060T2
公开(公告)日：2024-12-28
申请号：HUE19736566
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
-
公开(公告)号：AU2019294478B2
公开(公告)日：2023-03-23
申请号：AU2019294478
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. Formula (I). In particular, the present description relates to substituted bicyclic heterocyclic and heteroaryl compounds compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：AU2022201299A1
公开(公告)日：2022-03-24
申请号：AU2022201299
申请日：2022-02-25
Applicant: PTC THERAPEUTICS INC
Inventor： WOLL MATTHEW G , AMEDZO LUKIANA , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , KARP GARY MITCHELL , MAZZOTTI ANTHONY R , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , XU ZHENRONG
IPC: C07D239/74 , C07D239/94 , C07D239/95
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease. ,W1 W2 R2 W6 2~ (I) In particular, the present description relates to substituted bicyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：BR112021022624A2
公开(公告)日：2022-01-04
申请号：BR112021022624
申请日：2020-05-12
Applicant: PTC THERAPEUTICS INC
Inventor： TURPOFF ANTHONY , ANTHONY R MAZZOTTI , BHATTACHARYYA ANURADHA , MORRILL CHRISTIE , WANG GANG , GARY MITCHELL KARP , REN HONGYU , NARASIMHAN JANA , JIGAR S PATEL , AMEDZO LUKIANA , MATTHEW G WOLL , MD RAUFUL ALAM , MICHAEL A ARNOLD , SYDORENKO NADIYA , ZHANG NANJING , NATHANIEL T KENTON , NICHOLAS W MSZAR , BABU SURESH , TOM TUAN LUONG , ZHANG XIAOYAN , MOON YOUNG-CHOON
IPC: A61K31/53 , A61K31/501 , A61P25/28 , C07D401/14 , C07D413/14 , C07D417/14 , C07D487/04
Abstract: compostos para o tratamento da doença de huntington. a presente invenção refere-se a compostos, formas, e composições farmacêuticas dos mesmos e métodos de uso de tais compostos, formas, ou composições dos mesmos para tratar ou melhorar a doença de huntington. em particular, a presente descrição refere-se a compostos heteroarila monocíclicos substituídos de fórmula (i), fórmula (ii), ou fórmula (iii), formas e composições farmacêuticas dos mesmos e métodos de uso de tais compostos, formas, ou composições dos mesmos para tratar ou melhorar a doença de huntington.
-
Patent Agency Ranking
公开(公告)号：LT3386511T
公开(公告)日：2021-08-25
申请号：LT16874024
申请日：2016-12-11
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: C07D403/12 , A61K31/501 , A61K31/506 , A61K31/517 , C07D237/20 , C07D401/14 , C07D403/10 , C07D405/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/10 , C07D487/10
-
公开(公告)号：PE20211378A1
公开(公告)日：2021-07-27
申请号：PE2020002185
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , ALAM MD RAUFUL , ARNOLD MICHAEL A , BABU SURESH , BHATTACHARYYA ANURADHA , CHEN GUANGMING , GERASYUTO ALEKSEY I , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR , TURPOFF ANTHONY , WOLL MATTHEW G , YAN WUMING , ZHANG NANJING
IPC: C07D487/04 , A61K31/4985 , A61K31/5025 , A61P25/00 , A61P25/14 , A61P25/28 , C07D491/04 , C07D495/04 , C07D519/00
Abstract: Esta referido a compuestos de Formula I, en donde: R1 es cicloalquilo, heterociclilo C3-10-carbonilo; R2 es fenilo, heterociclilo, heteroarilo; W1 es C-Ra, CH-Ra, N, N-Rb, O, S; W2 es C-Ra, CH-Ra, N, N-Rb; W3 es C, CH, N; W4 y W5 son C-Ra o N. entre los compuestos preferidos tenemos los siguientes: 5-(1H-pirazol-4-il)-2-[1-(2,2,6,6-tetrametilpiperidin-4-il)-1H-imidazo[4,5-b]pirazin-5-il]fenol; 5-[2,5-difluoro-4-(1H-pirazol-4-il)fenil]-1-(2,2,6,6-tetrametilpiperidin-4-il)-1H-imidazo[4,5-b]pirazina; 5-(1H-pirazol-4-il)-2-[7-(2,2,6,6-tetrametilpiperidin-4-il)-7H-imidazo[4,5-c]piridazin-3-il]fenol; entre otros. Estos compuestos se emplean para tratar o mejorar la enfermedad de Huntington.
-
公开(公告)号：SG11202012869SA
公开(公告)日：2021-01-28
申请号：SG11202012869S
申请日：2019-06-25
Applicant: PTC THERAPEUTICS INC
Inventor： ZHANG NANJING , BABU SURESH , BARRAZA SCOTT J , BHATTACHARYYA ANURADHA , CHEN GUANGMING , KARP GARY MITCHELL , KASSICK ANDREW J , MAZZOTTI ANTHONY R , MOON YOUNG-CHOON , NARASIMHAN JANA , SYDORENKO NADIYA , TURPOFF ANTHONY , WOLL MATTHEW , YAN WUMING
IPC: C07D417/14 , A61K31/4439 , A61K31/454 , A61K31/46 , A61K31/496 , A61K31/5025 , A61K31/519 , A61K31/55 , A61P25/00 , A61P25/14 , A61P25/28 , C07D471/04 , C07D487/04 , C07D513/04 , C07D519/00
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted benzothiazole compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：SG11202009212WA
公开(公告)日：2020-10-29
申请号：SG11202009212W
申请日：2019-03-26
Applicant: PTC THERAPEUTICS INC
Inventor： SYDORENKO NADIYA , BABU SURESH , BHATTACHARYYA ANURADHA , MOON YOUNG-CHOON , NARASIMHAN JANA , PATEL JIGAR
IPC: C07D241/12 , C07D241/20 , C07D401/14
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
公开(公告)号：SG11201804915RA
公开(公告)日：2018-07-30
申请号：SG11201804915R
申请日：2016-12-11
Applicant: PTC THERAPEUTICS INC
Inventor： BABU SURESH , BHATTACHARYYA ANURADHA , HWANG SEONGWOO , JANI MINAKSHI , MOON YOUNG-CHOON , SYDORENKO NADIYA
IPC: A61K31/506 , A61P25/00 , C07D405/12
Abstract: The present description relates to compounds, forms, and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.In particular, the present description relates to substituted monocyclic heteroaryl compounds of Formula (I), forms and pharmaceutical compositions thereof and methods of using such compounds, forms, or compositions thereof for treating or ameliorating Huntington's disease.
-
-
-
-
-
-
-
-
-
Search Results
67
records
(took 0.023 seconds)
