公开(公告)号：DE3582016D1

公开(公告)日：1991-04-11

申请号：DE3582016

申请日：1985-10-25

Applicant: STANDARD OIL CO OHIO

Inventor： KUNG WEI-JEN HU ,  CESA MARK CLARK ,  BURRINGTON JAMES DAVID

IPC: C12P13/04 ,  C12P41/00

Abstract: Selective enzymatic hydrolysis of only the L-isomer of an L and D mixture of an alpha -N-acyl- alpha -amino acid ester whose alpha carbon atoms is chiral to yield a mixture containing L- alpha -amino acid and D- alpha -N-acyl- alpha -amino acid ester but essentially no D- alpha -amino acid is disclosed.

公开(公告)号：DK420489A

公开(公告)日：1991-02-26

申请号：DK420489

申请日：1989-08-25

Applicant: STANDARD OIL CO OHIO

Inventor： CESA MARK CLARK ,  DUBBERT ROBERT ALLEN ,  BURRINGTON JAMES DAVID

IPC: C07C227/12

公开(公告)号：DE3577310D1

公开(公告)日：1990-05-31

申请号：DE3577310

申请日：1985-11-04

Applicant: STANDARD OIL CO OHIO

Inventor： CESA MARK CLARK ,  BURRINGTON JAMES DAVID ,  DUBBERT ROBERT ALLEN

IPC: C07C237/00 ,  C07C231/10

公开(公告)号：DE3479797D1

公开(公告)日：1989-10-26

申请号：DE3479797

申请日：1984-11-07

Applicant: STANDARD OIL CO OHIO

Inventor： CESA MARK CLARK ,  BURRINGTON JAMES DAVID

IPC: C07C67/00 ,  C07C227/00 ,  C07C227/18 ,  C07C227/20 ,  C07C229/02 ,  C07C229/22 ,  C07C229/24 ,  C07C229/26 ,  C07C229/36 ,  C07C231/00 ,  C07C231/10 ,  C07C231/12 ,  C07C233/47 ,  C07C233/82 ,  C07C235/12 ,  C07C237/12 ,  C07C237/22 ,  C07C239/00 ,  C07C279/00 ,  C07C313/00 ,  C07C323/59 ,  C07D207/16 ,  C07D209/18 ,  C07D209/20 ,  C07D233/64 ,  C07B41/12 ,  C07C102/00 ,  C07C103/46 ,  C07C129/12 ,  C07C149/243 ,  C07C153/09 ,  C07C101/28

Abstract: Hydrocarboxylation of enamides with CO and a compound ROH yields amido acids or amido esters, which can be hydrolyzed to alpha -amino acids. This process avoids the use of HCN in the production of amino acids.

公开(公告)号：AT41917T

公开(公告)日：1989-04-15

申请号：AT86300221

申请日：1986-01-15

Applicant: STANDARD OIL CO OHIO

Inventor： PAGNOTTA MARCO ,  BURRINGTON JAMES DAVID ,  CESA MARK CLARK

IPC: C07C13/465 ,  B01J27/00 ,  B01J29/00 ,  C07B61/00 ,  C07C1/00 ,  C07C1/24 ,  C07C67/00 ,  C07C1/253

Abstract: Disclosed is the vapor phase cyclodehydration of an aldehyde or ketone over a solid Lewis acid as catalyst to make indene or a substituted indene according to the equation:

公开(公告)号：IT1186306B

公开(公告)日：1987-11-26

申请号：IT2108485

申请日：1985-06-10

Applicant: STANDARD OIL CO OHIO

Inventor： CESA MARK CLARK ,  BURRINGTON JAMES DAVID

IPC: C07C20060101 ,  C07C

Abstract: Prepn. of a cpd., of formula (I), hydrolysable to an alpha-aminoacid, of formula (II), comprises reacting an enamide of formula (III) with water or an organic hydroxy-cpd. of formula R6OH and carbon monoxide. (R1-6 each contains no ethylenic or acetylenic unsaturation, contains 0-15C, and is (i) H or hydrocarbyl; or (ii) hydrocarbyl gp. substd. by acylamino, acyl-(N-hydrocarbyl)amino, formylamino, formyl-(N-hydrocarbyl)amino, hydrocarbyloxy, hydrocarbylthio, acyloxy, acylthio, carboxy, hydrocarbyl-carboxy, hydrocarbyl-thiocarboxy, hydrocarbylamino, dihydrocarbylamino, hydrocarbonyl, hydrocarbylcarbonyl, 3-indolyl, carbamoyl, hydrocarbylcarbamoyl, dihydrocarbylcarbamoyl, 5-imidazolyl, 2-guanidinoyl or halogen; and R1 and R2 each may also be a value of the above substits. in (ii); and R6 can also be hydrocarbyl having 1 or more OH substits.; and R1 and R2, R1 and R3, or R2 and R3 can form a ring; and R4 can be linked with R1 or R2 to form a ring). Prodn. of (II) by hydrolysis of (I) is also claimed, esp. for prodn. of phenylalanine.

公开(公告)号：IT8521084D0

公开(公告)日：1985-06-10

申请号：IT2108485

申请日：1985-06-10

Applicant: STANDARD OIL CO OHIO

Inventor： CESA MARK CLARK ,  BURRINGTON JAMES DAVID

IPC: C07C20060101 ,  C07C