Abstract:
A method and apparatus for accurately determining the onset or occurrence of an epileptic seizure is disclosed. The system includes an electroencephalograph (EEG) (16a) and an electromyograph (EMG) (16b) which provide signals to signal processors (17a, 17b). The signal processor operates to generate a digitized envelope wave form of th EEG wave form and the EMG waveform. If the waveforms all have an amplitude within a predetermined threshold, for a predetermined time interval, a CPU (21) provides a signal to an output display (23) indicative of an epileptic seizure.
Abstract:
Disclosed is a system for use in trans-esophageal ultrasonic imaging of the heart comprising an electronics unit (22), a personal computer (24), a hand held pointer (28), a hand held probe (30) which generates an ultrasonic scanning pattern, an ultrasonic probe (14) in an endoscope (10). The hand held pointer (28) is subject to the same electromagnetic fields as the electromagnetic sensor of probe (14) produced by magnetic field generator (20). Both the position and orientation of the probe (30) is determined in terms of a three-dimensional coordinate system that lies outside the patient's body and is produced by magnetic field generator (20).
Abstract:
A power diode having substantially no reverse-recovery time and relatively high conductance. The power diode is a majority carrier semiconductor having a structure that is similar to that of a metal oxide semiconductor field effect transistor (MOSFET), in that it includes a source (38), a drain (38), a gate (42), and a body (36). In one embodiment, to increase conductance of the power diode, a linked-cell configuration that reverses the geometry of a conventional cell-type MOSFET is employed, thereby increasing the width of a conductance channel over that of a conventional MOSFET, and compensating for a relatively low level of inversion in the channel region. Negative and positive feedback circuits are used to further improve the conductance of the power diode by dynamically setting a bias voltage applied between the gate and the source to a level just below a threshold voltage.
Abstract:
The present invention relates to an intestinal peptide that is located in mammalian distal ileum. The peptide, designated "enteric neural peptide" or "ENP", corresponds to the N-terminal, 13 amino acid fragment of somatostatin-28. ENP is localized in cells that do not express S-28 and do not contain the C-terminal S-14 fragment of prosomatostatin. ENP increases in the circulation within 30 minutes of intake of mixed food, wherein the predominant nutrient signal is fat. Antibodies that bind ENP are also disclosed.
Abstract:
The present invention provides SPR sensors in which the sensing element is a planar lightpipe. The sensors of this invention include configurations that employ multi-wavelength light (including broad band and white light) incident on the SPR sensing area at a single angle or at a range of angles. Sensors and probes of this invention also include configurations that employ monochromatic light at a range of angles. Many of the configurations of the SPR lightpipes of this invention involve imaging of input light through the folded lightpipe. In one general embodiment, the invention provides a SPR sensor system in which the sensing element is a folded planar lightpipe.
Abstract:
The present invention provides SPR sensors in which the sensing element is a planar light pipe (20). The sensors of this invention include configurations which employ multiwavelength light incident on the SPR sensing area (30) at a single angle or at a range of angles. Sensors of this invention also include configurations that employ monochromatic light at a range of angles. Many of the configurations of the SPR light pipes of this invention involve imaging of input light through the light pipe. In one embodiment, the invention provides a first order SPR sensor system in which the sensing element is a planar light pipe. Light coupled into the light pipe reflects off an SPR sensing area positioned on an external surface planar surface of the light pipe. Multiwavelength light that is coupled into the light pipe input face at a range of angles propagates through the light pipe by total internal reflection (TIR), making multiple reflections, and exits in a series of angular bands each containing spectral information (including SPR features) for a small range of incidence angles. A detector or detectors are positioned to measure the reflection spectrum, including any surface plasmon resonance feature, of one or preferably more than one of the angular bands exiting the light pipe. SPR sensor configurations include those that have multiple sensing channels and those which can be multiplexed. This invention provides SPR sensors with planar light pipe sensing elements and method of detecting analytes in samples using these sensors. The invention also provides planar light pipe that have a plurality of SPR sensing layers on a planar surface.
Abstract:
The present invention provides discrete-length polyethylene glycol and polyethylene glycol containing compounds and methods for their preparation.
Abstract:
An apparatus and method for monitoring and motivating user compliance for orthodontic headgear (24) of the type using a linear spring-force module (22). The spring-force module (22) includes first (38) and second opposite attachment members that are interconnected to provide spring tension when moved linearly apart. A position sensor (16, 18, 19) detects linear movement between the attachment members. A microprocessor (12) receives signals from the position sensor to determine wear duration, force magnitude, and whether such movement is sufficiently variable to be biological in origin or is attempted mimicry. Multiple determinations made by the processor are recorded over time to provide an evaluation of headgear wear compliance and to provide ongoing motivation for user compliance.
Abstract:
An isolated nucleic acid molecule that hybridizes under stringent conditions to SEQ ID NO:1 or its complement and to the DNA of enterohemorrhagic E. coli O157:H7 but not to the DNA of enteropathogenic E. coli O55:H7.
Abstract translation:在严格条件下与SEQ ID NO:1或其补体和肠出血性大肠杆菌O157:H7的DNA杂交而不是肠致病性大肠杆菌O55:H7的DNA的分离的核酸分子。