公开(公告)号：WO1996028089A1

公开(公告)日：1996-09-19

申请号：PCT/US1996001996

申请日：1996-02-15

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  McGAFFIGAN, Thomas, H.

IPC: A61B05/028

CPC classification number: A61M25/0012 ,  A61B5/028 ,  Y10T29/49083 ,  Y10T29/49865

Abstract: A heater (12) for a catheter (10) used in monitoring constant cardiac output is fabricated using a bifilar wire (21) coated with polyvinyl chloride (PVC) like that used for the catheter. The bifilar wire is coated with the PVC using a conventional extrusion technique, producing a coated lead (24, 32). The coated lead is wrapped around the exterior surface of the catheter, forming a helical coil. Heat is applied to the coated lead to melt the PVC coating, causing it to bond the lead to the catheter. The melted PVC also flows into gaps (23) or notches between adjacent coils of the lead, producing a relatively smooth outer surface for the heater when cooled.

Abstract translation: 用于监测恒定心输出量的用于导管（10）的加热器（12）使用涂覆有用于导管的聚氯乙烯（PVC）的双股线（21）来制造。 使用常规的挤出技术将双绞线用PVC涂覆，生产涂层引线（24,32）。 涂覆的导线缠绕在导管的外表面上，形成螺旋线圈。 对涂覆的铅施加热量以熔化PVC涂层，使其将导线粘合到导管上。 熔化的PVC还流入相邻线圈之间的间隙（23）或缺口，在冷却时产生相对平滑的加热器外表面。

公开(公告)号：WO1994028788A1

公开(公告)日：1994-12-22

申请号：PCT/US1994006138

申请日：1994-05-31

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DIXON, Robert, C. ,  LAPP, Theodore, R. ,  BOBO, Donald, E., Jr.

IPC: A61B05/028

CPC classification number: A61B5/028 ,  A61B5/7232 ,  A61B5/7257

Abstract: A system for measuring fluid flwo within a conduit (10), such as blood flow from the heart, includes a heating element (12) that is driven so as to apply heat to the fluid at an upstream position as a series of periodic heat signal. A temperature sensor (14) located downstream measures a local temperature of the fluid and generates an electrical fluid temperature signal corresponding to the local temperature. This signal is then applied to a dispersive filter (22), which outputs a pulse-like signal in the presence of each periodic heat signal. Fluid flow is then calculated by a processor (18) as a function of the area under an estimated impulse response curve for the channel in which the fluid flows. Each periodic heat signal is preferably sinusoidal and has an instantaneous frequency that varies substantially continuously between a first frequency and a second frequency over a predetermined active input signal period. In a preferred embodiment, the frequency varies linearly between a first and a second frequency over a predetermined time period. The output signal from the filter (22), which is itself an estimate of the channel impulse response, is preferably integrated in order to provide a parameter estimate that is inversely proportional to flow. The corresponding method of measuring fluid flow using a frequency-swept input heat signal and matched dispersive filtering is included.

Abstract translation: 一种用于测量导管（10）内的流体（例如来自心脏的血流）的系统包括加热元件（12），该加热元件被驱动以便在上游位置处将流体作为一系列周期性热信号 。 位于下游的温度传感器（14）测量流体的局部温度并产生对应于局部温度的电流体温度信号。 然后将该信号施加到色散滤光器（22），其在每个周期性热信号的存在下输出脉冲状信号。 然后，处理器（18）根据流体流动的通道的估计脉冲响应曲线下的面积来计算流体流动。 每个周期性热信号优选地是正弦的并且具有在预定的有效输入信号周期上在第一频率和第二频率之间基本上连续变化的瞬时频率。 在优选实施例中，频率在预定时间段内在第一和第二频率之间线性变化。 来自滤波器（22）的输出信号本身是信道脉冲响应的估计，优选地被集成，以便提供与流量成反比的参数估计。 包括使用频率扫描输入热信号和匹配色散滤波测量流体流量的相应方法。

公开(公告)号：WO1994020017A1

公开(公告)日：1994-09-15

申请号：PCT/US1994002230

申请日：1994-03-01

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  SWENDSON, David, L. ,  ATTAL, Lucien

IPC: A61B05/028

CPC classification number: A61B5/028

Abstract: An improved integral flow-through injectate delivery system (10) comprises fluid flow means (24) having a proximal and a distal end. The proximal end comprises a first port having fluid inlet means (44) for connecting the flow means (24) to a source of fluid injectate (28) and a second port (46) adapted to be connected to a syringe means (18). The distal end of the fluid flow means (24) is adapted to be connected to a fluid delivery means (30) for delivering the injectate to the patient and the syringe means (18) is adapted to direct injectate fluid from the injectate source (28) through the fluid inlet (44) and the fluid flow means (24) to the fluid delivery means (30). A first check valve (34) is in fluid-flow communication with the fluid inlet means (44) and the fluid flow means (24) and a second check valve means (36) is in fluid-flow communication with the fluid flow means (24) and the fluid delivery means (30). A sensing means (22) is disposed within the fluid flow means (24) at its distal end for sensing a characteristic of fluid flowing therethrough, usually temperature. A fluid flow regulating means (72) is placed within the fluid flow means (24) between the fluid inlet means (44) and the sensing means (22) to delay or limit injectate from flowing therethrough except when being directed by the syringe means (18).

Abstract translation: 改进的整体流通注射输送系统（10）包括具有近端和远端的流体流动装置（24）。 近端包括具有用于将流动装置（24）连接到流体注射源（28）的流体入口装置（44）的第一端口和适于连接到注射器装置（18）的第二端口（46）。 流体流动装置（24）的远端适于连接到用于将注射器输送到患者的流体输送装置（30），并且注射器装置（18）适于引导从注射源（28）注入流体 ）通过流体入口（44）和流体流动装置（24）到达流体输送装置（30）。 第一止回阀（34）与流体入口装置（44）和流体流动装置（24）流体连通，第二止回阀装置（36）与流体流动装置 24）和流体输送装置（30）。 感测装置（22）在其远端处设置在流体流动装置（24）内，用于感测流过其中的流体的特性，通常是温度。 流体流动调节装置（72）被放置在流体入口装置（44）和感测装置（22）之间的流体流动装置（24）内，以延迟或限制注射液流过其中，除非由注射器装置 18）。

公开(公告)号：WO1993021822A1

公开(公告)日：1993-11-11

申请号：PCT/EP1993001034

申请日：1993-04-29

Applicant: PFEIFFER, Ulrich ,  KNOLL, Reinhold

IPC: A61B05/028

CPC classification number: A61B5/028

Abstract: A device for determining the volume and/or throughflow of a section of a human or animal circulatory system has a liquid reservoir (1) containing a liquid kept at a temperature different from that of the blood of the patient, an injection device (12) linked by a pumping device (3) to the liquid reservoir (1) in order to inject liquid from the liquid reservoir (1) into the circulatory system of a patient, a temperature sensor (13) for measuring the temperature in the circulatory system of the patient downstream of the injection spot and an evaluating device (20) which receives the measurement values from the temperature sensor (13) and other measurement parameters. The injected liquid is kept at the ambient temperature and the pumping device (3) injects the liquid in pulses, so that measurement can be continuously carried out while injecting each time a small amount of liquid.