公开(公告)号：WO1995017260A1

公开(公告)日：1995-06-29

申请号：PCT/US1994002904

申请日：1994-03-17

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DIPERNA, Paul

IPC: B04B05/02

CPC classification number: B04B7/02 ,  F02B2075/025

Abstract: A centrifugation system (10) includes a frame (12) having at least one weight supporting member (450) for engaging a support surface lying in a generally horizontal plane. The system also includes a centrifuge assembly (230), supported by a base (464) and including a chamber having an axis of rotation (344), which lies in a plane offset from a vertical plane orthogonal to the support surface. The sloped centrifuge conserves vertical height and makes possible for all components to be located in a zone between the user's chest and knees when standing.

Abstract translation: 离心系统（10）包括具有至少一个重量支撑构件（450）的框架（12），用于接合位于大致水平面的支撑表面。 该系统还包括由基座（464）支撑并且包括具有旋转轴线（344）的腔室的离心机组件（230），其位于与垂直于支撑表面的垂直平面偏移的平面中。 倾斜的离心机保持垂直高度，使所有部件都可以位于使用者的胸部和膝盖之间的区域。

公开(公告)号：WO1994025172A1

公开(公告)日：1994-11-10

申请号：PCT/DE1994000469

申请日：1994-04-28

Applicant: WEISE, Heinz

IPC: B04B05/02

CPC classification number: B04B5/02 ,  B01D45/14

Abstract: A centrifuge with a rotor having a rotary drive and inlet and outlet devices has a rotor (8) with a plurality of separator tubes (9, 10) distributed over the circumference which are arranged substantially towards the rotor axis (11) at a radial distance from the rotor axis (11). The separator tubes can be radially pivoted or moved about a pivot axis (13, 14). The inlet device (15) opens into the separator tubes via radial connecting pipes (16, 17). Unlike prior art centrifuge structures with a rotating drum, the invention requires less material, is lighter and has a lower mass to be accelerated.

公开(公告)号：WO1993012887A1

公开(公告)日：1993-07-08

申请号：PCT/US1992011216

申请日：1992-12-23

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  WILLIAMSON, Warren, P., IV

IPC: B04B05/02

CPC classification number: B04B5/0428 ,  B04B5/0442 ,  B04B7/02 ,  B04B2005/045 ,  B04B2005/0492

Abstract: A drawer-mounted (36) centrifuge (12) provides easy access for loading and unloading disposable processing elements (22). The centrifuge also includes an umbilicus holder (86) that moves between an operating position and an out-of-way position as the drawer opens and closes.

Abstract translation: 抽屉式（36）离心机（12）可方便地进行装卸一次性处理元件（22）。 离心机还包括在抽屉打开和关闭时在操作位置和离开位置之间移动的脐带保持器（86）。

公开(公告)号：WO1991018675A1

公开(公告)日：1991-12-12

申请号：PCT/US1991002175

申请日：1991-04-01

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DENNEHEY, T., Michael ,  WEST, Joseph, C., Jr.

IPC: B04B05/02

CPC classification number: A61M1/3693 ,  A61M1/3696 ,  A61M2202/0415 ,  B04B5/0428 ,  B04B5/0442 ,  A61M2202/0092

Abstract: A device and method are provided for separating mononuclear cells from red blood cell depleted plasma in a centrifuge blood cell separator. The device includes an inlet (51) for receiving plasma, an area (63) for receiving mononuclear cells, and an outlet (53) for receiving mononuclear cell depleted plasma. The distance and flow path (65) between the inlet (51) and outlet (53) being so constructed and arranged as to cause mononuclear cells to sediment out into the area (63) for receiving the mononuclear cells and causing at least 66 % of the platelets contained in the plasma to flow to and through the outlet.

公开(公告)号：WO1982002842A1

公开(公告)日：1982-09-02

申请号：PCT/AU1982000015

申请日：1982-02-19

Applicant: LOWAN PTY LTD ,  KELSEY CHRISTOPHER GEORGE

Inventor： LOWAN PTY LTD

IPC: B04B05/02

CPC classification number: B04B5/02

Abstract: Des particules fines telles que des particules de minerai dans une boue sont separees en fonction de leur densite par acceleration centrifuge cyclique produite par rotation d'une chambre (40) autour de son propre axe et d'un autre axe. Des particules de densite plus grande sont extraites de la chambre (40) dans la region de sa paroi laterale la plus eloignee de l'autre axe.

公开(公告)号：WO1998017397A1

公开(公告)日：1998-04-30

申请号：PCT/US1997018571

申请日：1997-10-20

Applicant: WINKELMAN, James, W. ,  ZINDER, Oren ,  GRUMBERG, Manfred ,  SCHREIBMAN, Jacob

IPC: B04B05/02

CPC classification number: B04B5/0414 ,  G01N33/491

Abstract: Red cells are separated from plasma or serum of whole blood by arranging an evacuated tube (2) sealed by a self-sealing stopper (26) above and preferably coaxial with a tube (4) containing a blood sample and sealed by a self-sealing stopper (28). A hollow double ended needle (14) is held by a fixture (6) and is disposed between and coaxial with the tubes (2, 4) and the tubes are placed in the fixture (6) in a vertical position in a centrifuge (84) and rotated about and spaced from an axis parallel to the axis of the tubes and needle. After the red cells are separated from the serum and/or plasma, the tubes (2, 4) are pushed toward one another so that the needle (14) penetrates both stoppers and the serum and/or plasma is drawn into the upper tube (2). The tubes (2, 4) and needle (14) are separated while still being rotated so that the whole blood components are separated as required.

Abstract translation: 将红细胞与全血的血浆或血清分离，通过布置由自密封止动器（26）密封的真空管（2），所述真空管（2）由含有血液样品的管（4）上方并优选地同轴，并通过自密封 塞子（28）。 中空的双头针（14）由固定装置（6）保持并且设置在管（2,4）之间并且与管（2,4）同轴，并且管在垂直位置放置在离心机（84）中 ）并且绕平行于管和针的轴线的轴线旋转并且间隔开。 在从血清和/或血浆中分离红细胞后，将管（2,4）彼此推动，使得针（14）穿过两个塞子，将血清和/或血浆拉入上管（ 2）。 管（2,4）和针（14）在仍然旋转的同时分离，使得全部血液成分根据需要分离。

公开(公告)号：WO1998016321A1

公开(公告)日：1998-04-23

申请号：PCT/US1997018548

申请日：1997-10-15

Applicant: CORNAY, Paul, J.

IPC: B04B05/02

CPC classification number: B04B1/04 ,  B01J2219/00078 ,  B01J2219/0009 ,  B01J2219/00132 ,  B01J2219/00155 ,  B01J2219/00159 ,  B01J2219/00162 ,  B04B1/00 ,  B04B11/02

Abstract: A centrifuge includes a housing having a central body (262) and a hollow arm (344) attached to and extending from the body. The arm (344) has an end cap (348) to form a chamber in the arm. A baffle with a longer inner tube (326) and a shorter outer tube (328) is attached to the body (262) and extends into the chamber. The longer tube (326) is positioned inside the shorter tube (328) and defines an inner space (324) therebetween. An outer space (378) is defined between the shorter tube (328) and the hollow arm (344). An entrance path (250) for the mixture of initial material is formed in the housing (262) and communicates with the inner space (324). An exit path for the light material (254) is formed in the housing (262) and communicates with the outer space (378). An exit path (252) for the heavier material is formed in the housing (262) and includes the interior of the longer tube (326). A plug is formed adjacent the end cap (348).

Abstract translation: 离心机包括具有中心体（262）和附接到主体并从身体延伸的中空臂（344）的壳体。 臂（344）具有端盖（348）以在臂中形成腔室。 具有较长内管（326）和较短外管（328）的挡板附接到主体（262）并延伸到腔室中。 较长的管（326）位于较短的管（328）内部并且在其间限定内部空间（324）。 在较短管（328）和中空臂（344）之间限定外部空间（378）。 用于混合初始材料的入口路径（250）形成在壳体（262）中并与内部空间（324）连通。 在外壳（262）中形成用于轻材料（254）的出口路径，并与外部空间（378）连通。 用于较重材料的出口路径（252）形成在壳体（262）中并且包括较长管（326）的内部。 邻近端盖（348）形成插头。

公开(公告)号：WO1997022413A1

公开(公告)日：1997-06-26

申请号：PCT/US1996019192

申请日：1996-12-02

Applicant: SORVALL PRODUCTS, L.P.

Inventor： SORVALL PRODUCTS, L.P. ,  ROMANAUSKAS, William, A.

IPC: B04B05/02

CPC classification number: B04B5/0421

Abstract: A swinging bucket centrifuge rotor (10) comprises a body (12) that has a reference plane (10R) that extends generally perpendicular to a vertically extending axis of rotation (10A). The body (12) has at least one pair of confronting planar sidewalls (24A, 24B) each of which has a trunnion pin (30) mounted thereon. Each trunnion pin (30) has an axis (30A) therethrough that extends generally perpendicularly to the planar sidewall (24A, 24B) on which the pin (30) is mounted. Each sidewall (24A, 24B) further has a generally cylindrical swinging bucket support surface (40) thereon. Each cylindrical support surface (40) has an axis of generation (40A) that lies in the reference plane (10R) in parallel relationship to the axis (30A) of the trunnion pin (30). Thus, a portion of each cylindrical support surface (40) lies above and below the reference plane (10R).

Abstract translation: 摆动式离心机转子（10）包括主体（12），该主体具有大致垂直于垂直延伸的旋转轴线（10A）延伸的参考平面（10R）。 主体（12）具有至少一对相对的平面侧壁（24A，24B），每个侧壁具有安装在其上的耳轴销（30）。 每个耳轴销（30）具有穿过其中的轴线（30A），该轴线（30A）大致垂直于安装销（30）的平面侧壁（24A，24B）延伸。 每个侧壁（24A，24B）上还具有大致圆柱形的摆动铲斗支撑表面（40）。 每个圆柱形支撑表面（40）具有与轴颈销（30）的轴线（30A）平行的位于参考平面（10R）中的产生轴线（40A）。 因此，每个圆柱形支撑表面（40）的一部分位于参考平面（10R）的上方和下方。

公开(公告)号：WO1997009118A1

公开(公告)日：1997-03-13

申请号：PCT/US1996014172

申请日：1996-09-05

Applicant: SORVALL PRODUCTS, L.P.

Inventor： SORVALL PRODUCTS, L.P. ,  BARKUS, David, Alan ,  HANLE, Daniel, Dale

IPC: B04B05/02

CPC classification number: B04B7/02 ,  B04B5/0414 ,  B04B2007/025

Abstract: The cover (24) for a fixed angle centrifuge rotor (10) has an array of container support surfaces (44) depending from the lower surface (24B) thereof. Each support surface (44) is substantially cylindrical in configuration and has an axis (44A) associated therewith. Each container support surface (44) is associated with a respective one of the cavities (18) formed in the rotor body (12). In the most general case, when the rotor cover (24) is attached to the rotor body (12), the axis (44A) of each container support surface (44) lies in the same common radial plane (38) as do the axis (18A) of the cavity (18) with which the support surface (44) is associated and the axis of rotation. In the common radial plane (38), the axis (44A) of a support surface (44) is inclined at a predetermined angle with respect to the axis of rotation. The axis (44A) of the support (44) may further be arranged to lie in parallel relationship to the axis (18A) of the cavity (18) with which it is associated, or may define a predetermined angle with respect thereto.

Abstract translation: 用于固定角度离心机转子（10）的盖（24）具有从其下表面（24B）悬垂的容器支撑表面（44）的阵列。 每个支撑表面（44）基本上是圆柱形的并且具有与其相关联的轴线（44A）。 每个容器支撑表面（44）与形成在转子体（12）中的相应的一个空腔（18）相关联。 在最通常的情况下，当转子盖（24）附接到转子体（12）时，每个容器支撑表面（44）的轴线（44A）位于与轴线相同的公共径向平面（38） （18）的与所述支撑表面（44）相关联的空腔（18A）和所述旋转轴线。 在公共径向平面（38）中，支撑表面（44）的轴线（44A）相对于旋转轴线以预定角度倾斜。 支撑件（44）的轴线（44A）还可以布置成与其相关联的空腔（18）的轴线（18A）平行，或者可以相对于其限定预定角度。

公开(公告)号：WO1993008920A1

公开(公告)日：1993-05-13

申请号：PCT/US1992009269

申请日：1992-10-29

Applicant: E.I. DU PONT DE NEMOURS AND COMPANY

Inventor： E.I. DU PONT DE NEMOURS AND COMPANY ,  ROMANAUSKAS, William, Andrew

IPC: B04B05/02

CPC classification number: B04B5/0414 ,  B04B2005/0435

Abstract: An adapter (10) having a body (12) and a cooperating cover (14) with a seal (16) therebetween is characterized by a stop surface (22S1) provided on the exterior surface of the body (12). The body and the cover are held together by a clamping bail (18) that is either separate from or, more preferably, pivotally mounted to the body (12). The bail (18) is slidably movable over the body (12) and the cover (14) from an open to a clamping position. In the clamping position the bail abuts against the stop surface (22S1) with the major axis of the bail being most preferably collinear with the major axis of the adapter. With the bail (18) in the clamping position the cover (14) is held to the body in a manner that compresses the seal (16) therebetween. The bail (18) is formed of a material having sufficient strength to withstand a vertical force created by the pressure of a liquid carried in the tube under centrifugation.