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    Method and Apparatus for Actuating an Acousto-Optical Component
    192.
    发明申请
    Method and Apparatus for Actuating an Acousto-Optical Component 审中-公开

    公开(公告)号：US20180231416A1

    公开(公告)日：2018-08-16

    申请号：US15320567

    申请日：2015-06-19

    Applicant: Carl Zeiss Microscopy GmbH

    Inventor： Burkhard ROSCHER ,  Stefan WILHELM ,  Gunter MOEHLER

    IPC: G01J3/12 ,  G02B21/00 ,  G02F1/11 ,  G01J3/06

    CPC classification number: G01J3/1256 ,  G01J3/06 ,  G02B21/002 ,  G02B21/16 ,  G02F1/113 ,  G02F1/116 ,  G02F2203/21

    Abstract: A method and apparatus for actuating an acousto-optical component for manipulating light passing therethrough, in particular for manipulating the illumination and/or detection light in the beam path of a microscope, preferably a laser scanning microscope, where the illumination and/or detection wavelength is adjusted by means of at least one frequency generator connected to the acousto-optical component and controlling the manipulation, the frequency generator generates a signal which generates a spectral spread for the intensity distribution of the wavelength of the illumination and/or detection light for ensuring a temperature-independent manipulation. Actuation is effected by two or more actuation signals in such a way that two or more overlapping and/or superposing main lobes of the transfer function of the acousto-optical component or main maxima are generated.

    Scanning microscope and acousto-optical main beam splitter for a scanning microscope
    193.
    发明授权
    Scanning microscope and acousto-optical main beam splitter for a scanning microscope 有权

    公开(公告)号：US09933686B2

    公开(公告)日：2018-04-03

    申请号：US14916520

    申请日：2014-09-03

    Applicant: LEICA MICROSYSTEMS CMS GMBH

    Inventor： Vishnu Vardhan Krishnamachari

    IPC: G02F1/33 ,  G01J3/12 ,  G02B21/00 ,  G02B27/28 ,  G02F1/11

    CPC classification number: G02F1/33 ,  G01J3/1256 ,  G02B21/0032 ,  G02B21/0064 ,  G02B21/0068 ,  G02B27/283 ,  G02F1/116

    Abstract: The invention relates to an acousto-optic main beam splitter for a scanning microscope, which is embodied and intended to direct illuminating light having a preselected or preselectable illuminating light wavelength into an illumination beam path for illumination of a sample, and to direct detected light coming from a sample into a detection beam path. The acousto-optic main beam splitter is characterized in that a mechanical wave having an acoustic frequency associated with the illuminating light wavelength propagates, or multiple mechanical waves that have the same acoustic frequency associated with the illuminating light wavelength propagate, in the acousto-optic main beam splitter, both a portion of the detected light bundle having the illuminating light wavelength and a first linear polarization direction, and a portion of the detected light having the illuminating light wavelength and a second linear polarization direction perpendicular to the first linear polarization direction, being deflected out of the detected light bundle coming from a sample by interaction with the one mechanical wave or by interaction with the mechanical waves, and are thereby removed from the detected light bundle; and/or the acousto-optic main beam splitter being embodied to direct, by interaction with the one mechanical wave or by interaction with the mechanical waves, both the portion of illuminating light that has the preselected illuminating light wavelength and a first linear polarization direction, and the portion of illuminating light that has the preselected illuminating light wavelength and a second linear polarization direction that is different from, in particular perpendicular to, the first linear polarization direction, into an illumination beam path for illumination of a sample.

    LIGHT SOURCE APPARATUS AND INSPECTION APPARATUS
    195.
    发明申请
    LIGHT SOURCE APPARATUS AND INSPECTION APPARATUS 有权
    光源装置和检查装置

    公开(公告)号：US20160334652A1

    公开(公告)日：2016-11-17

    申请号：US15153569

    申请日：2016-05-12

    Applicant: Lasertec Corporation

    Inventor： Jun Sakuma

    IPC: G02F1/11 ,  G02B27/14 ,  G01J1/04 ,  H01S3/00 ,  G01N21/95 ,  G02F1/355 ,  G02F1/35

    CPC classification number: G02F1/113 ,  G01J1/0407 ,  G01J3/1256 ,  G01N21/1702 ,  G01N21/636 ,  G01N21/9501 ,  G01N2201/06113 ,  G01N2201/068 ,  G02B27/141 ,  G02F1/116 ,  G02F1/3534 ,  G02F1/3551 ,  H01S3/005 ,  H01S3/0085 ,  H01S3/0092 ,  H01S3/1306 ,  H01S3/2391

    Abstract: Provided are a light source apparatus and an inspection apparatus that can stably output a wavelength converted light beam. A light source apparatus includes a laser light source that generates a first fundamental light beam, at least one nonlinear optical crystal that generates a wavelength converted light beam using the fundamental light beam or a harmonic laser beam of the fundamental light beam as an incident light beam, a detector that detects the wavelength converted light beam, an acousto-optic modulator that is disposed in an optical path of the incident light beam in such a way that a zero-order light beam enters the nonlinear optical crystal, and a controller that controls an output intensity of the wavelength converted light beam according to a detection signal from the detector.

    Abstract translation: 提供能够稳定地输出波长转换光束的光源装置和检查装置。 光源装置包括产生第一基本光束的激光光源，至少一个非线性光学晶体，其使用基本光束的基波束或基波束的谐波激光产生波长转换光束作为入射光束 ，检测波长转换光束的检测器，设置在入射光束的光路中的声光调制器，使得零级光束进入非线性光学晶体，以及控制器，其控制 根据来自检测器的检测信号，波长转换光束的输出强度。

    Microparticle analysis device and microparticle analysis method
    197.
    发明授权
    Microparticle analysis device and microparticle analysis method 有权
    微粒分析装置及微粒分析方法

    公开(公告)号：US08350232B2

    公开(公告)日：2013-01-08

    申请号：US13017554

    申请日：2011-01-31

    Applicant: Atsushi Fukumoto ,  Mitsuru Toishi

    Inventor： Atsushi Fukumoto ,  Mitsuru Toishi

    IPC: G01N21/64

    CPC classification number: G01J3/1256 ,  G01J3/4406 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1459 ,  G01N21/51 ,  G01N21/645 ,  G01N2021/4707

    Abstract: Disclosed herein is a microparticle analysis device including: a light source configured to irradiate a microparticle with light; an acousto-optic modulator configured to diffract fluorescence generated from the microparticle due to the light irradiation; a slit configured to allow transmission of only diffracted light in a diffraction center wavelength region among diffracted light beams from the acousto-optic modulator; and a detector configured to detect the diffracted light in the diffraction center wavelength region transmitted through the slit.

    Abstract translation: 本发明公开了一种微粒分析装置，其特征在于，包括：被配置为用光照射微粒的光源; 配置为衍射由于光照射而从微粒产生的荧光的声光调制器; 狭缝，被配置为允许在来自声光调制器的衍射光束中的衍射中心波长区域中仅衍射衍射光; 以及检测器，被配置为检测通过狭缝透射的衍射中心波长区域中的衍射光。

    Coherency Reduction for Bandwidth Measurement
    198.
    发明申请
    Coherency Reduction for Bandwidth Measurement 审中-公开
    一致性降低带宽测量

    公开(公告)号：US20120162657A1

    公开(公告)日：2012-06-28

    申请号：US13411600

    申请日：2012-03-04

    Applicant: Robert J. Rafac ,  Scot T. Smith

    Inventor： Robert J. Rafac ,  Scot T. Smith

    IPC: G01J3/45

    CPC classification number: G01J3/02 ,  G01J1/4257 ,  G01J3/0205 ,  G01J3/027 ,  G01J3/0291 ,  G01J3/0297 ,  G01J3/1256 ,  G01J3/26 ,  G01J9/02 ,  G01J2009/0249 ,  G01J2009/0257 ,  G02B5/04 ,  G02B5/284 ,  G02B27/48 ,  G03F7/70025 ,  G03F7/70583 ,  H01S3/005

    Abstract: A method includes directing a portion of a laser beam output from a laser along a secondary beam path toward a detector, the secondary beam path being distinct from a main beam path of the laser beam; generating a bandwidth selective interference pattern of the laser beam on the detector; detecting, at the detector, a width of a fringe within the interference pattern to thereby measure measuring a bandwidth of the laser beam; and homogenizing the laser beam traveling along the secondary beam path prior to generation of the bandwidth selective interference pattern. The homogenizing includes diffusing the laser beam; and introducing a time dependent, position dependent, or both time and position dependent random modulation to the wavefront of the laser beam to reduce fluctuations in the detected fringe width and to reduce the influence of spatial coherence of the laser beam on the detected interference pattern.

    Abstract translation: 一种方法包括将从激光器输出的激光束的一部分沿着次级光束路径引向检测器，次级光束路径与激光束的主光束路径不同; 在检测器上产生激光束的带宽选择性干涉图案; 在检测器处检测干涉图案内的边缘的宽度，从而测量测量激光束的带宽; 并且在产生带宽选择干涉图案之前均匀化沿着次级光束路径行进的激光束。 均质化包括扩散激光束; 并且将与时间有关的位置依赖性或时间和位置相关随机调制引入到激光束的波前以减少检测到的条纹宽度的波动并减少激光束的空间相干性对检测到的干涉图案的影响。

    AOTF-BASED IMAGING SYSTEM AND METHOD FOR HYPERSPECTRAL AND MULTISPECTRAL IMAGING OF SPECIMENS INCLUDING MEDICAL TISSUE
    200.
    发明申请
    AOTF-BASED IMAGING SYSTEM AND METHOD FOR HYPERSPECTRAL AND MULTISPECTRAL IMAGING OF SPECIMENS INCLUDING MEDICAL TISSUE 有权
    基于AOTF的成像系统和方法，用于包括医疗组织的样本的高分辨和多重图像成像

    公开(公告)号：US20100246907A1

    公开(公告)日：2010-09-30

    申请号：US12675677

    申请日：2008-09-02

    Applicant: Elliot S. Wachman ,  Jill Wachman ,  Stanley J. Geyer

    Inventor： Elliot S. Wachman ,  Jill Wachman ,  Stanley J. Geyer

    IPC: G06K9/00 ,  H04N7/18

    CPC classification number: G01J3/2823 ,  G01J3/1256 ,  G01N21/6428 ,  G01N21/6458 ,  G01N33/5438 ,  G01N2021/6421 ,  G01N2021/6441 ,  G01N2021/6471 ,  G01N2201/067 ,  G02F1/116 ,  G02F2201/122 ,  G02F2203/055

    Abstract: An imaging system includes a platform for placement of a sample or an animal to be imaged, and at least one excitation light source for irradiating the sample or animal to stimulate an emission at a plurality of different center wavelengths. An acousto-optic tunable filter (AOTF) is provided that includes a piezoelectric transducer crystal for emitting an acoustic wave having a ground electrode disposed on one side of the piezoelectric crystal. A patterned electrode layer is disposed on a side of the piezoelectric crystal opposite the ground electrode. The patterned electrode layer includes a continuous region proximate to its center and a discontinuous region, a pattern in the discontinuous region comprising a plurality of spaced apart features electrically connected to the continuous region, and an AO interaction crystal receiving the acoustic wave attached to the ground electrode or the patterned electrode layer.

    Abstract translation: 成像系统包括用于放置待成像的样品或动物的平台，以及用于照射样品或动物以刺激多个不同中心波长的发射的至少一个激发光源。 提供了一种声光可调滤波器（AOTF），其包括用于发射声波的压电换能器晶体，该声波具有设置在压电晶体一侧的接地电极。 图案化电极层设置在与接地电极相对的压电晶体的一侧。 图案化电极层包括靠近其中心的连续区域和不连续区域，不连续区域中的图案包括电连接到连续区域的多个间隔的特征，以及接收附着于地面的声波的AO相互作用晶体 电极或图案化电极层。

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