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公开(公告)号:US20220062883A1
公开(公告)日:2022-03-03
申请号:US17418581
申请日:2020-01-03
Inventor: Taeghwan HYEON , Byounghoon LEE
IPC: B01J35/00 , B01J21/06 , B01J37/02 , B01J37/00 , B01J37/04 , B01J37/08 , B01J23/745 , B01J23/75 , B01J23/755 , B01J23/72 , B01J23/46 , B01J35/08
Abstract: A single atom catalyst and a method of forming the same are provided. The single atom catalyst comprises a support comprising a first metal oxide and a second metal atom located in the first metal oxide. The method of forming the single atom catalyst comprises forming a sacrificial nanoparticle, coating the sacrificial nanoparticle with a first metal oxide, adsorbing a second metal atom to the first metal oxide, forming a sacrificial layer on the support, and heating the first metal oxide.
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公开(公告)号:US20220002388A1
公开(公告)日:2022-01-06
申请号:US17468590
申请日:2021-09-07
Applicant: INSTITUTE FOR BASIC SCIENCE
Inventor: Won Do HEO , Yun Ju Lee , Daseuli Yu , Byung Ouk Park
Abstract: The present invention relates to the preparation of an antibody analogue capable of being activated reversibly, and uses thereof, and provides a fusion protein comprising an inactive first fragment of an antibody analogue is fused to a stimulus-induced dimerization protein.
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公开(公告)号:US20220002362A1
公开(公告)日:2022-01-06
申请号:US17293568
申请日:2019-11-13
Applicant: INSTITUTE FOR BASIC SCIENCE
Inventor: Wondo HEO , Sungsoo KIM , Sang Kyu LEE , Taeyoon KYUNG
IPC: C07K14/47 , C07K14/705 , C12N15/86
Abstract: Provided is a CRY2 variant in which E279 and/or E281 having a negative charge in a N277SEGE281 sequence of SEQ ID NO: 1 is substituted with any one selected from the neutral amino acid group of alanine (A), isoleucine (I), leucine (L), valine (V), phenylalanine (F), methionine (M) and tryptophan (W), or in which S278 or G280 of a N277SEGE281 sequence of SEQ ID NO: 1 is substituted with any one selected from the bulky amino acid group of tryptophan (W) and phenylalanine (F).
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公开(公告)号:US20210381968A1
公开(公告)日:2021-12-09
申请号:US17340696
申请日:2021-06-07
Inventor: Seok-Cheol HONG , Il Boem LEE , Minhaeng CHO , Hyeonmin MOON , Jin-Sung PARK
Abstract: Disclosed is an interferometric scattering microscope. The interferometric scattering microscope includes a remote refocusing system adapted to reproduce light collected by a high numerical aperture objective lens using another objective lens and thus can acquire an image of an object in a sample without vertical movement of the objective lens or the sample.
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公开(公告)号:US11190343B2
公开(公告)日:2021-11-30
申请号:US16200016
申请日:2018-11-26
Applicant: INSTITUTE FOR BASIC SCIENCE
Inventor: Kyung Ah Shim
Abstract: An electronic device including a key generator is disclosed. The key generator acquires a first affine map, a second affine map, and a third map, and generates a public key using the first affine map, the second affine map, and the third map, the third map is a system of multivariate quadratic polynomials having n variables and m equations, at least one of the multivariate quadratic polynomials has oil-oil quadratic terms with non-zero coefficients, and the third map includes at least one set for defining vinegar variables used in an Oil and Vinegar method and index sets for defining oil variables used in the Oil and Vinegar method, and each of the first affine map, the second affine map, and the third map is a finite field.
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公开(公告)号:US20210292759A1
公开(公告)日:2021-09-23
申请号:US16346251
申请日:2017-11-01
Inventor: Won Jong KIM , Jeong Hun KIM , Jihyun LEE , Byung Joo LEE
IPC: C12N15/115 , A61K31/713 , A61K47/61 , A61P35/00 , A61P27/02
Abstract: The present invention relates to a method for producing dextran polymer-based amplified nucleic acid aptamer nanoconstructs which efficiently and selectively capture a specific target molecule, the method comprising linking a short nucleic acid sequence or a complementary sequence for formation of nanoconstructs and a nucleic acid aptamer sequence for capture of the specific target molecule to a dextran polymer by a chemical reaction, mixing the resulting polymer/nucleic acid substances with each other to form nanostructures, subjecting the nanostructures to rolling circle amplification, thereby forming a nucleic acid aptamer having a repeated structure. The dextran polymer-based amplified nucleic acid aptamer nanoconstructs have the effect of efficiently and selectively capturing a specific target molecule.
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公开(公告)号:US11046661B2
公开(公告)日:2021-06-29
申请号:US16959863
申请日:2019-01-02
Inventor: Sukbok Chang , Seung Youn Hong , Yoon Su Park , Yeongyu Hwang , Yeong Bum Kim
IPC: C07D273/01 , C07D413/06 , C07D209/34 , C07D491/22 , C07D209/54 , C07D205/12 , C07D215/227
Abstract: The present invention relates to a method for producing a lactam compound from dioxazolone in the presence of a catalyst having a particular ligand, and to a lactam compound produced thereby, and can produce a lactam compound with excellent selectivity and an excellent yield by using the combination of a starting material having a particular functional group and a particular catalyst having a particular ligand.
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公开(公告)号:US20210128486A1
公开(公告)日:2021-05-06
申请号:US17253068
申请日:2019-06-17
Inventor: Taeghwan HYEON , Hyekjin KWON , Dokyoon KIM
Abstract: A nanoparticle structure is provided. The nanoparticle structure comprises a core comprising first nanoparticles and a shell located on a surface of the core and comprising second nanoparticles. The first nanoparticles may comprise magnetic nanoparticles, and the second nanoparticles may comprise catalytic nanoparticles.
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公开(公告)号:US20200330969A1
公开(公告)日:2020-10-22
申请号:US16959880
申请日:2019-01-02
Inventor: Sukbok CHANG , Seung Youn HONG , Yoon Su PARK , Yeongyu HWANG , Yeong Bum KIM
IPC: B01J31/22 , C07F17/02 , C07D207/267 , C07D209/70 , C07D209/46 , C07D405/04 , C07D409/04 , C07D209/54 , C07D209/52 , C07D209/56 , C07D403/04 , C07J43/00
Abstract: The present invention relates to a novel metal complex, a method for producing same, and a method for producing a gamma-lactam compound using same, and the metal complex according to the present invention is used as a catalyst for producing a gamma-lactam compound and can efficiently produce a gamma-lactam compound with an excellent yield and excellent selectivity.
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公开(公告)号:US20200292733A1
公开(公告)日:2020-09-17
申请号:US16888955
申请日:2020-06-01
Inventor: Hyun Seok LEE , Young Hee LEE
Abstract: A wavelength multiplexing device is disclosed. When light is irradiated on a first longitudinal end region of a metal nano-structure, surface plasmon polaritons are generated in the first longitudinal end region. The surface plasmon polaritons and the light are coupled with each other to form first coupled surface plasmon polaritons, wherein the first coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure. When the first coupled surface plasmon polaritons reach a two-dimensional material layer, excitons are induced in the two-dimensional material layer, wherein the induced excitons and the first coupled surface plasmon polaritons are coupled with each other to form second coupled surface plasmon polaritons. The second coupled surface plasmon polaritons propagate along and on a surface of the metal nano-structure toward a second longitudinal end thereof.
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