中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

1331 records (took 0.045 seconds)

    SYSTEMS AND METHODS FOR BALANCE STABILIZATION
    216.
    发明申请
    SYSTEMS AND METHODS FOR BALANCE STABILIZATION 审中-公开
    用于平衡稳定的系统和方法

    公开(公告)号：WO2013134873A1

    公开(公告)日：2013-09-19

    申请号：PCT/CA2013/050184

    申请日：2013-03-12

    Applicant: THE HOSPITAL FOR SICK CHILDREN ,  UNIVERSITY HEALTH NETWORK

    Inventor： CUSHING, Sharon ,  PAPSIN, Blake ,  POTHIER, David ,  HUGHES, Cian

    IPC: A61F11/00 ,  A61F11/04 ,  A61N1/05 ,  A61N1/36

    CPC classification number: A61N1/36032 ,  A61N1/36036

    Abstract: A system for rehabilitating patients affected by balance disorders with or without vestibular hypofunction and/or malfunction with or without an associated hearing loss, which includes sensors of sound and head movement, processing circuitry, a power source coupled to head phones, an air conduction hearing aid, bone conduction hearing aid, middle ear implant or an electrical stimulator implanted into the cochlea capable of stimulating areas within the cochlea with the potential for current spread to surrounding non- auditory areas including the vestibular system.

    Abstract translation: 影响平衡障碍患者的系统，包括或不伴有或不伴有相关听力损失的前庭功能障碍和/或故障，包括声音和头部运动的传感器，处理电路，耦合到头戴式电话的电源，空气传导听觉 助听器，骨传导助听器，中耳植入物或植入耳蜗中的电刺激器，其能够刺激耳蜗内的区域，具有潜在的电流扩散到包括前庭系统在内的周围非听觉区域。

    BIOMARKERS FOR EARLY DETERMINATION OF A CRITICAL OR LIFE THREATENING RESPONSE TO ILLNESS AND MONITORING RESPONSE TO TREATMENT THEREOF
    217.
    发明申请
    BIOMARKERS FOR EARLY DETERMINATION OF A CRITICAL OR LIFE THREATENING RESPONSE TO ILLNESS AND MONITORING RESPONSE TO TREATMENT THEREOF 审中-公开
    生物标志物，用于早期确定关键或生命对无效的监测和监测对其治疗的反应

    公开(公告)号：WO2013127000A1

    公开(公告)日：2013-09-06

    申请号：PCT/CA2013/000192

    申请日：2013-02-27

    Applicant: UNIVERSITY HEALTH NETWORK (UHN)

    Inventor： KAIN, Kevin ,  LILES, Conrad, W. ,  ERDMAN, Laura ,  CONROY, Andrea

    IPC: G01N33/68 ,  G01N33/53

    CPC classification number: G01N33/56983 ,  G01N33/53 ,  G01N33/569 ,  G01N33/56905 ,  G01N33/56916 ,  G01N33/56944 ,  G01N33/68 ,  G01N33/6893 ,  Y02A50/53 ,  Y02A50/56 ,  Y02A50/58

    Abstract: The invention relates to the use of novel biomarkers and biomarker combinations having utility in the early determination of an individual's critical and/or life threatening response to illness and/or in predicting outcome of said illness. The measurement of expression levels of the products of the biomarkers and combinations of biomarkers of the invention have utility in making the determination of an individual's critical and/or life threatening response to illness. In some embodiments, the biomarker and biomarker combinations are agnostic and are independent of the pre-identification and/or determination of the cause or nature of the illness. In some embodiments, the biomarkers and biomarker combinations can be utilized to monitor the effectiveness of treatment interventions for an individual who has a critical illness.

    Abstract translation: 本发明涉及使用新的生物标志物和生物标志物组合，其可用于早期确定个体对疾病的危及生命和/或威胁生命的反应和/或预测所述疾病的结果。 本发明的生物标志物的产物和生物标志物的组合的表达水平的测量可用于确定个体对疾病的关键和/或威胁生命的反应。 在一些实施方案中，生物标志物和生物标志物组合是不可知的，并且独立于疾病的原因或性质的预先识别和/或确定。 在一些实施方案中，生物标志物和生物标志物组合可用于监测具有严重疾病的个体的治疗干预的有效性。

    COMPOSITIONS OF TIGECYCLINE AND USES THEREOF
    218.
    发明申请
    COMPOSITIONS OF TIGECYCLINE AND USES THEREOF 审中-公开
    TIGECYCLINE的组合物及其用途

    公开(公告)号：WO2013078554A1

    公开(公告)日：2013-06-06

    申请号：PCT/CA2012/001114

    申请日：2012-12-03

    Applicant: UNIVERSITY HEALTH NETWORK

    Inventor： SCHIMMER, Aaron, D. ,  JITKOVA, Ioulia

    IPC: A61K47/22 ,  A61K31/65 ,  A61K47/12 ,  A61K47/14 ,  A61P31/04 ,  A61P35/00 ,  A61P35/02 ,  C07C237/26

    CPC classification number: A61K31/65 ,  A61K9/0019 ,  A61K31/194 ,  A61K31/375 ,  A61K31/724 ,  A61K47/12 ,  A61K47/14 ,  A61K47/183 ,  A61K47/22 ,  A61K47/40 ,  A61K47/6951 ,  B82Y5/00 ,  C08B37/0015 ,  C08L5/16 ,  A61K2300/00

    Abstract: Compositions for stabilizing tigecycline are provided, the compositions including one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. Compositions of stabilized tigecycline are also provided comprising tigecycline and one or more formulating agent(s) selected from a chelator, pyruvic acid, or a salt or ester thereof and ascorbic acid and optionally one or more excipients, diluents or buffers. The compositions can also include a cyclodextrin. Methods of preparing, uses and kits are also provided.

    Abstract translation: 提供用于稳定替加环素的组合物，所述组合物包括一种或多种选自螯合剂，丙酮酸或其盐或酯的配制剂和抗坏血酸以及任选的一种或多种赋形剂，稀释剂或缓冲剂。 还提供了稳定的替加环素的组合物，其包含替加环素和选自螯合剂，丙酮酸或其盐或酯和抗坏血酸以及任选的一种或多种赋形剂，稀释剂或缓冲剂的一种或多种配制剂。 组合物还可以包括环糊精。 还提供了制备方法，用途和试剂盒。

    APNEA AND HYPOPNEA DETECTION USING BREATH PATTERN RECOGNITION
    220.
    发明申请
    APNEA AND HYPOPNEA DETECTION USING BREATH PATTERN RECOGNITION 审中-公开
    APNEA和HYPOPNEA检测使用呼吸模式识别

    公开(公告)号：WO2012155251A1

    公开(公告)日：2012-11-22

    申请号：PCT/CA2012/000478

    申请日：2012-05-17

    Applicant: UNIVERSITY HEALTH NETWORK ,  ALSHAER, Hisham ,  FERNIE, Geoffrey Roy ,  BRADLEY, T. Douglas

    Inventor： ALSHAER, Hisham ,  FERNIE, Geoffrey Roy ,  BRADLEY, T. Douglas

    IPC: A61B5/08 ,  A61B5/083

    CPC classification number: A61B7/04 ,  A61B5/087 ,  A61B5/4818 ,  A61B5/6803 ,  A61B5/7257 ,  A61B5/7282 ,  A61B7/003 ,  A61B2562/0204

    Abstract: Disclosed herein is a method and device for apnea and hypopnea detection. In one embodiment, a method is provided for detecting apneas and hypopneas from a digitized breath sound recording acquired from a candidate suspected of sleep apnea. The method comprises scanning an amplitude profile of the digitized breath sound recording to identify a prospect event segment; evaluating characteristics of the prospect event segment for consistency with one or more preset apnea-specific criteria; classifying the prospect event segment as representative of an apnea upon it satisfying each of the one or more apnea-specific criteria; evaluating the prospect event characteristics for consistency with one or more preset hypopnea-specific criteria distinct from the apnea-specific criteria; and classifying the prospect event segment as representative of a hypopnea upon it satisfying each of the one or more hypopnea-specific criteria.

    Abstract translation: 本文公开了一种呼吸暂停和呼吸不足检测的方法和装置。 在一个实施例中，提供了一种从怀疑为睡眠呼吸暂停的候选者获取的数字化呼吸音记录中检测呼吸暂停和呼吸不足的方法。 该方法包括扫描数字化呼吸音记录的幅度分布以识别潜在事件段; 评估前景事件段的特征，以与一个或多个预设的呼吸暂停特异性标准保持一致; 将前景事件段分类为代表呼吸暂停的符合每个一个或多个呼吸暂停特异性标准的前景事件段; 评估前景事件特征，以与一个或多个与呼吸暂停特异性标准不同的预设呼吸不足特异性标准保持一致; 并将前景事件分段作为代表呼吸不足的代表，满足每个一个或多个呼吸不足特异性标准。

Patent Agency Ranking