公开(公告)号：US06796697B1

公开(公告)日：2004-09-28

申请号：US10140486

申请日：2002-05-07

Applicant: Chris Bragg ,  Daniel Scott ,  Eliezer Rosengaus

Inventor： Chris Bragg ,  Daniel Scott ,  Eliezer Rosengaus

IPC: F21V704

CPC classification number: G02B6/02 ,  G01N21/8806 ,  G01N21/9501 ,  G01N21/956 ,  G01N2021/8812 ,  G01N2201/0631 ,  G01N2201/0635 ,  G01N2201/0638 ,  G01N2201/0806 ,  G01N2201/0826 ,  G02B5/0252 ,  G02B5/32 ,  G02B6/04 ,  G02B6/4298

Abstract: An illumination delivery system provides a spatially and angularly uniform shaped beam output with sufficient intensity to illuminate a sample surface for defect inspection. Light is transmitted through a shaped fiber optic bundle, a homogenizer, a diffuser, and an optional focusing optics system.

Abstract translation: 照明传送系统提供具有足够强度的空间和角度均匀成形的光束输出，以照射样品表面进行缺陷检查。 光通过成形的光纤束，均质器，扩散器和可选的聚焦光学系统传输。

公开(公告)号：US20030187344A1

公开(公告)日：2003-10-02

申请号：US10372763

申请日：2003-02-21

Applicant: XENOGEN CORPORATION

Inventor： David Nilson ,  Brad Rice ,  Tamara Troy

IPC: A61B005/05

CPC classification number: G01N21/6456 ,  A01K1/031 ,  A61M16/104 ,  A61M16/18 ,  A61M16/202 ,  A61M2016/0039 ,  G01N2021/1787 ,  G01N2021/6463 ,  G01N2021/6471 ,  G01N2021/6484 ,  G01N2201/0227 ,  G01N2201/0826

Abstract: A macroscopic fluorescence illumination assembly is provided for use with an imaging apparatus with a light-tight imaging compartment. The imaging apparatus includes an interior wall defining a view port extending into the imaging compartment to enable viewing of a specimen contained therein. The illumination assembly includes a specimen support surface sized and dimensioned for receipt in the imaging compartment, and oriented to face toward the view port of the imaging apparatus. The support surface is substantially opaque and defines a window portion that enables the passage of light there through. The window portion is selectively sized and dimensioned such that the specimen, when supported atop the support surface, can be positioned and seated over the window portion in a manner forming a light-tight seal substantially there between. The illumination assembly further includes an excitation light source, and a bundle of fiber optic strands having proximal ends thereof in optical communication with the light source. The distal ends of the strands terminate proximate the window portion of the support surface. The distal ends each emit a respective beam of light originating from the light source which are then collectively directed toward the window portion and into a bottom side of the specimen wherein the diffused light passes there through and exits a topside thereof for receipt through the view port to view the fluorescence of the specimen.

Abstract translation: 提供了一种宏观荧光照明组件，用于与具有不透光成像室的成像装置一起使用。 该成像设备包括限定了一个视图端口的内壁，该视图端口延伸到成像室中以使得能够观察其中容纳的样本。 照明组件包括尺寸和尺寸适于接收在成像室中的样本支撑表面，并且被定向成面向成像设备的视口。 支撑表面基本上是不透明的，并且限定了能够使光通过的窗口部分。 窗口部分被选择性地定尺寸和尺寸使得当被支撑在支撑表面上方时，样本可以以基本上在其之间形成不透光密封的方式被定位和安置在窗口部分上。 照明组件还包括激发光源，以及一束光纤束，其光纤束的近端与光源光学连通。 股线的末端终止于支撑表面的窗口部分。 远端各自发出源自光源的相应光束，然后将它们共同指向窗口部分并进入样本的底侧，其中漫射光通过其并穿过其顶侧并通过观察端口接收 以观察样品的荧光。

公开(公告)号：US20030178577A1

公开(公告)日：2003-09-25

申请号：US10338051

申请日：2003-01-08

Inventor： Petri Aronkyto

IPC: G01N021/64

CPC classification number: G01N21/645 ,  G01N21/6452 ,  G01N2021/6484 ,  G01N2201/0826

Abstract: An apparatus for measuring fluorescence from a sample, where an excitation system includes optical fibers or optical fiber bundles each starting from two or more lasers and mingled so as to form a single optical fiber bundle. Excitation light beams can be passed separately or simultaneously directly via this optical fiber bundle or via a common optical fiber bundle to a sample.

Abstract translation: 一种用于测量来自样品的荧光的装置，其中激发系统包括光纤或光纤束，每个光纤或光纤束从两个或更多个激光器开始并混合以形成单个光纤束。 激发光束可以通过该光纤束或通过公共光纤束分别或同时直接通过到样品。

公开(公告)号：US5386295A

公开(公告)日：1995-01-31

申请号：US005321

申请日：1993-01-15

Applicant: Steven C. Switalski ,  David S. Uerz ,  Alan J. Lowne ,  James R. Sandifer ,  Hsue-Yang Liu

Inventor： Steven C. Switalski ,  David S. Uerz ,  Alan J. Lowne ,  James R. Sandifer ,  Hsue-Yang Liu

IPC: G01J1/44 ,  G01J3/08 ,  G01J3/28 ,  G01J3/51 ,  G01N21/31 ,  G01N21/35 ,  G02B26/04 ,  G01J3/02 ,  G01N21/64 ,  G01N21/65

CPC classification number: G01J3/42 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0232 ,  G01J3/0235 ,  G01J3/0289 ,  G01J3/08 ,  G01J3/44 ,  G01N21/314 ,  G02B26/04 ,  G01J2001/4242 ,  G01J2003/1213 ,  G01J2003/2866 ,  G01N2021/3133 ,  G01N2021/3159 ,  G01N2021/3174 ,  G01N2021/4742 ,  G01N21/359 ,  G01N2201/0826 ,  G01N2201/1283

Abstract: A postacquired spectrophotometer, for use with a sample and reference. The spectrophotometer has a filter unit, defining an axis of movement, and pluralities of designated sites and dark sites disposed in uniform relation to the axis. The designated and dark sites are disposed in alternation. Alternating designated sites have apertures and filters covering the apertures. Further, a main member, coaxial with the filter unit, has sample and reference beam paths, which are intersected by the sites. The main member has disposed, in operative relation to the actuators, an actuator sensor, which generates an integration actuator signal upon alignment with each integration actuator and a clamping actuator signal upon alignment with each clamping actuator. Moreover, a drive continuously moves the filter unit relative to the axis and beam paths. Further, a light distribution system directs light separately from the sample and reference to respective beam paths, and then to a detector, which produces a detector signal responsive to light received. Finally, means for processing the signals is provided, including a clamping circuit, integrators, and a demultiplexer.

Abstract translation: 一个采用分光光度计的分光光度计，用于样品和参考。 分光光度计具有限定运动轴线的过滤器单元以及与轴线均匀关系地设置的多个指定位置和暗点。 指定的和黑暗的地点交替处置。 交替指定的位置具有覆盖孔的孔和过滤器。 此外，与过滤器单元同轴的主构件具有与位置相交的样品和参考光束路径。 主构件以致动器的方式相对于致动器设置致动器传感器，其在与每个积分致动器对准时产生积分致动器信号，并且在与每个夹紧致动器对准时产生夹紧致动器信号。 此外，驱动器相对于轴和梁路连续地移动过滤单元。 此外，配光系统将光从样品分开引导并参考各个光束路径，然后引导到检测器，该检测器响应于所接收的光产生检测器信号。 最后，提供用于处理信号的装置，包括钳位电路，积分器和解复用器。

公开(公告)号：US5317379A

公开(公告)日：1994-05-31

申请号：US833530

申请日：1992-02-11

Applicant: Frederick M. Ryan ,  James W. Thomson

Inventor： Frederick M. Ryan ,  James W. Thomson

IPC: G01J3/12 ,  G01N21/25 ,  G01J3/06 ,  G01N21/31 ,  G01N21/35

CPC classification number: G01N21/253 ,  G01J3/1256 ,  G01N2201/0826

Abstract: An analyzer measures properties of multiple chemical samples, and includes an optical filter element having a long axis and positioned at a location where simultaneous multiple light beams, corresponding to the chemical samples to be measured, form a diffuse light spot elongated along an axis which is substantially aligned with the filter element long axis. The analyzer also includes a light source, filter means incorporating the filter element for transmitting spectrally selected portions of the light beams, sample cell means for exposing each sample to its associated light beam, and detector means for detecting the light beams after modification by the samples and after transmission by the filter. In a preferred embodiment, optical fibers carry the light beams to and from the chemical samples.

Abstract translation: 一种分析仪测量多个化学样品的性质，并且包括具有长轴并且位于与要测量的化学样品相对应的同时多个光束形成沿轴线延伸的漫射光点的位置处的光学滤光元件， 基本上与过滤元件长轴对齐。 分析仪还包括一个光源，滤光片装置结合有滤光元件，用于透射光谱选择的光束部分，用于将每个样品暴露于其相关联的光束的采样单元装置，以及用于检测由样本修改之后的光束的检测器装置 并通过过滤器传输。 在优选实施例中，光纤将光束传送到化学样品和从化学样品携带光束。

公开(公告)号：US5216488A

公开(公告)日：1993-06-01

申请号：US780958

申请日：1991-10-23

Applicant: Jukka Tguunanen ,  Aimo Kainiemi

Inventor： Jukka Tguunanen ,  Aimo Kainiemi

IPC: G01N21/01 ,  G01N21/25

CPC classification number: G01N21/253 ,  G01N2201/0407 ,  G01N2201/0826

Abstract: The invention relates to a method and apparatus for conducting light onto cuvettes in a photometer. Onto each cuvette in a row, there is successively conducted light through a moving light-cutting disc (8), which is provided with a slot (10) at each light path. Thus the light passing through the adjacent cuvette does not disturb the measurement.

Abstract translation: 本发明涉及一种用于在光度计中对比色皿进行光的方法和装置。 在连续的每个比色皿上，通过在每个光路处设置有狭槽（10）的移动的光盘（8）连续地引导光。 因此，穿过相邻的比色皿的光不会影响测量。

公开(公告)号：US5172192A

公开(公告)日：1992-12-15

申请号：US478328

申请日：1990-02-12

Applicant: William S. Prather

Inventor： William S. Prather

IPC: G01N21/25

CPC classification number: G01N21/255 ,  G01N2201/0636 ,  G01N2201/0826 ,  G01N2201/0833

Abstract: A spectrophotometric probe for in situ absorption spectra measurements comprising a first optical fiber carrying light from a remote light source, a second optical fiber carrying light to a remote spectrophotometer, the proximal ends of the first and second optical fibers parallel and coterminal, a planoconvex lens to collimate light from the first optical fiber, a reflecting grid positioned a short distance from the lens to reflect the collimated light back to the lens for focussing on the second optical fiber. The lens is positioned with the convex side toward the optical fibers. A substrate for absorbing analyte or an analyte and reagent mixture may be positioned between the lens and the reflecting grid.

Abstract translation: 一种用于原位吸收光谱测量的分光光度探测器，包括：携带来自远程光源的光的第一光纤，将光传输到远程分光光度计的第二光纤，第一和第二光纤的近端平行和共同生成，平凸透镜 以准直来自第一光纤的光，反射栅格位于离透镜短距离处以将准直光反射回透镜以聚焦在第二光纤上。 透镜以凸面朝向光纤定位。 用于吸收分析物或分析物和试剂混合物的基底可以位于透镜和反射格栅之间。

公开(公告)号：US5143224A

公开(公告)日：1992-09-01

申请号：US667430

申请日：1991-03-11

Applicant: Steven P. Burchell

Inventor： Steven P. Burchell

IPC: B03B7/00 ,  B07C5/342 ,  C01B31/06 ,  G01N21/65 ,  G01N21/85 ,  G01N21/87

CPC classification number: G01N21/87 ,  B07C5/3425 ,  B07C5/368 ,  G01N21/65 ,  G01N21/85 ,  G01N2021/656 ,  G01N2201/0826 ,  G01N2201/0833 ,  Y10S209/906

Abstract: A method for separating diamonds from associated gangue in a diamondiferous material. The method comprises the steps of mixing the diamondiferous material with water to form a slurry and passing the slurry through laser radiation of known wavelength in the infra red part of the electromagnetic spectrum to cause Raman spectral scattering of the radiation from the slurry. The scattered radiation is collected and filtered to isolate diamond-relevant radiation and the filtered radiation is analyzed to determine whether it is indicative of the presence of diamond. Finally, on the basis of such analysis, high diamond content slurry is separated from low diamond content slurry.

Abstract translation: 用于从金刚石材料中分离钻石与相关ang石的方法。 该方法包括以下步骤：将金刚石材料与水混合以形成浆料，并使浆料通过已知波长的激光辐射在电磁谱的红外部分中，以引起来自浆料的辐射的拉曼光谱散射。 收集和过滤散射的辐射以分离钻石相关的辐射，并分析过滤的辐射以确定其是否指示存在钻石。 最后，在这种分析的基础上，将高金刚石含量浆料与低金刚石含量浆料分离。

公开(公告)号：US5085517A

公开(公告)日：1992-02-04

申请号：US429963

申请日：1989-10-31

Applicant: Curt H. Chadwick ,  Robert R. Sholes ,  John D. Greene ,  Francis D. Tucker, III ,  Michael E. Fein ,  P. C. Jann ,  David J. Harney ,  William Bell ,  Bin-Ming B. Isai ,  Walter I. Novak ,  Mark J. Wihl

Inventor： Curt H. Chadwick ,  Robert R. Sholes ,  John D. Greene ,  Francis D. Tucker, III ,  Michael E. Fein ,  P. C. Jann ,  David J. Harney ,  William Bell ,  Bin-Ming B. Isai ,  Walter I. Novak ,  Mark J. Wihl

IPC: G01B11/24 ,  G01B11/30 ,  G01N21/64 ,  G01N21/88 ,  G01N21/93 ,  G01N21/956 ,  G01R31/308 ,  G06T1/00 ,  G06T1/20

CPC classification number: G01R31/308 ,  G01N21/956 ,  G01N2021/8887 ,  G01N2021/95615 ,  G01N2021/95638 ,  G01N21/64 ,  G01N21/95607 ,  G01N2201/06126 ,  G01N2201/0826

Abstract: In each configuration, at least one TDI sensor is used to image the portions of interest of the substrate that are substantially uniformly or critically illuminated. In one configuration, the substrate is compared to the expected characteristic features prestored in memory. In a second configuration, a first and second pattern in a region of at least one substrate are inspected by comparing one pattern against the other and noting whether they agree with each other. This is accomplished by illuminating the two patterns, imaging the first pattern and storing its characteristics in a temporary memory, then imaging the second pattern and comparing it to the stored characteristics from the temporary memory. Then the comparisons continue sequentially with the second pattern becoming the first pattern in the next imaging/comparison sequence against a new second pattern. With each comparison whether there has been agreement between the two patterns is noted. After all of the patterns are sequentially compared, the bad ones are identified by identifying those that did not compare with other patterns in the test process. This inspection technique is useful for doing die-to-die inspections, as well as repeating patern inspections within the same die. A variation of the second configuration uses two TDI sensors to simultaneously image the first and second patterns eliminating the need for the temporary memory.

公开(公告)号：US5019710A

公开(公告)日：1991-05-28

申请号：US331404

申请日：1989-03-30

Applicant: Gunnar Wennerberg ,  Daniel A. Gordon ,  Harriss T. King

Inventor： Gunnar Wennerberg ,  Daniel A. Gordon ,  Harriss T. King

IPC: G01N21/35 ,  G01N21/86

CPC classification number: G01N21/86 ,  G01N2021/8645 ,  G01N2201/0826 ,  G01N2201/0833 ,  G01N2201/1085

Abstract: A system for detecting optically-sensitive properties of sheet materials during manufacture includes a first group of bundles of optical fibers that convey light to selected transmitting locations adjacent one face of the sheet material. The system further includes a second group of bundles of optical fibers that collect and convey light transmitted through the sheet material to a light detector. The light detector measures the intensity of light received from each of the bundles of the second group to provide measurements of optically-sensitive properties of the sheet material at selected cross-directional locations.