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    Fourier transform infrared spectrophotometer
    212.
    发明专利
    Fourier transform infrared spectrophotometer 有权
    FOURIER变换红外分光光度计

    公开(公告)号：JP2003014543A

    公开(公告)日：2003-01-15

    申请号：JP2001202935

    申请日：2001-07-04

    Applicant: Shimadzu Corp ,  株式会社島津製作所

    Inventor： OTA HIROSHI

    IPC: G01J3/45 ,  G01J3/42 ,  G01J3/453 ,  G01N21/35

    CPC classification number: G01J3/453

    Abstract: PROBLEM TO BE SOLVED: To eliminate the influence to an absorption spectrum even if interference waveform is distorted by the mixture of noise and the unstable factors of a light source and a detector. SOLUTION: Two measurement interference waveform data that are continuous in time are held in a memory onec (S12), the amount of noise and the degree of similarity are calculated from the data at an end section and at a center section, respectively (S14, S15), and an index value E for judging whether interference waves are conforming or not is obtained from them (S16). When the index value E is equal to or less than a threshold Et that is determined by measurement in advance, it is judged that the interference waves are appropriate and the waveform is integrated (S17, S18). In the case of the mixture of noise due to turbulence or the like, and the unstable state until a light source and a detector reach a stable state, the index value E increases, so that it is judged to be-nonconforming waveform and is excluded from integration, thus preventing the integral waveform from being distorted and increasing the accuracy also in absorption spectrum obtained from Fourier transform from it.

    Abstract translation: 要解决的问题：即使干扰波形被噪声的混合和光源和检测器的不稳定因素扭曲，也可以消除对吸收光谱的影响。 解决方案：将时间上连续的两个测量干扰波形数据保存在存储器中（S12），分别根据端部和中心部分的数据计算噪声量和相似度（S14， S15），以及用于判断干扰波是否一致的指标值E（S16）。 当索引值E等于或小于预先通过测量确定的阈值Et时，判断干扰波是适当的并且波形被积分（S17，S18）。 在由湍流等引起的噪声混合的情况下，以及在光源和检测器达到稳定状态之前的不稳定状态，指标值E增加，从而判定为不符合波形并被排除 从而整合，从而防止积分波形失真，并且在从其傅里叶变换获得的吸收光谱中也提高精度。

    Optical spectrum analyzer high in wavelength resolution and method for measuring optical signal with the same
    213.
    发明专利
    Optical spectrum analyzer high in wavelength resolution and method for measuring optical signal with the same 审中-公开
    波长分辨率高的光谱分析仪和用于测量光信号的方法

    公开(公告)号：JP2003004532A

    公开(公告)日：2003-01-08

    申请号：JP2001185516

    申请日：2001-06-19

    Applicant: Nippon Telegr & Teleph Corp ,  Ntt Advanced Technology Corp ,  エヌ・ティ・ティ・アドバンステクノロジ株式会社 ,  日本電信電話株式会社

    Inventor： TOYODA SEIJI ,  KURIHARA TAKASHI ,  YANAGAWA TSUTOMU

    IPC: G01J3/453 ,  G01J9/00 ,  G02B5/28

    Abstract: PROBLEM TO BE SOLVED: To provide a useful optical spectrum analyzer high in wavelength resolution having simple construction including a small number optical parts without a mechanical driving part, and a method for measuring optical signal with the analyzer.
    SOLUTION: A signal light and a locally oscillated light generated by a local oscillator 12 are mixed into a heterodyne signal at an optical mixer (photo coupler) 13 and detected by an electric spectrum analyzer 15. A tunable filter 16, which consists of a polymer waveguide, is placed in the front stage of the mixer 13 and activated by applying a current to the triangular electrodes for a heater of a phase shifter mounted in an array of waveguide. The frequency of the local oscillator 12 is tunable oscillation. The signal light is detected with locally oscillated light by means of heterodyne detection to pick up the profile of the differential frequency component, which is the intermediate frequency of the heterodyne signal as a beat signal, by the electric spectrum analyzer.
    COPYRIGHT: (C)2003,JPO

    Abstract translation: 要解决的问题：提供一种具有简单结构的高分辨率的有用的光谱分析仪，其包括少量没有机械驱动部件的光学部件，以及用分析仪测量光信号的方法。 解决方案：由本地振荡器12产生的信号光和局部振荡的光在光学混合器（光耦合器）13处混合成外差信号，并由电谱分析仪15检测。可调谐滤波器16由聚合物 波导，被放置在混合器13的前级，并通过向安装在波导阵列中的移相器的加热器的三角形电极施加电流而被激活。 本地振荡器12的频率是可调振荡。 通过外差检测用本地振荡光检测信号光，通过电谱分析仪拾取作为差频信号的外差信号的中频的差分频率分量的分布。

    214.
    发明专利
    失效

    公开(公告)号：JP3351536B2

    公开(公告)日：2002-11-25

    申请号：JP54596098

    申请日：1998-03-27

    IPC: G01N33/48 ,  C12M1/00 ,  C12M3/00 ,  C12N15/09 ,  C12N15/11 ,  C12Q1/68 ,  G01J3/02 ,  G01J3/12 ,  G01J3/26 ,  G01J3/28 ,  G01J3/44 ,  G01J3/453 ,  G01N1/28 ,  G01N21/64 ,  G01N21/75 ,  G01N33/483 ,  G01N33/50 ,  G01N33/52 ,  G01N33/569 ,  G01N33/58 ,  G01N37/00 ,  G02B21/00 ,  G02B21/16 ,  G06K9/00 ,  G06K9/76

    Abstract: A method for finding L internal reference vectors for classification of L chromosomes or portions of chromosomes of a cell, the L chromosomes or portions of chromosomes being painted with K different fluorophores or combinations thereof, wherein K basic chromosomes or portions of chromosomes of the L chromosomes or portions of chromosomes are each painted with only one of the K different fluorophores, whereas the other L-K of the L chromosomes or portions of chromosomes are each painted with a different combination of the K different fluorophores, the method comprising the steps of (a) using a multi-band collection device for measuring a first vector for each pixel of each of the L chromosomes or portions of chromosomes; (b) identifying pixels belonging to each of the K basic chromosomes or portions of chromosomes and defining the pixels as basic pixels, so as to obtain K basic classes of basic pixels; (c) using at least one basic pixel from each of the K basic classes for obtaining K basic vectors, the K basic vectors being K internal reference vectors; (d) using the K basic vectors for identifying pixels belonging to the other L-K chromosomes or portions of chromosomes; and (e) using the pixels belonging to the other L-K chromosomes or portions of chromosomes for calculating the other L-K internal reference vectors, thereby finding all of the L internal reference vectors. A method for classification of L chromosomes or portions of chromosomes of a cell similarly painted using the above method for finding L internal reference vectors, and using the L reference vectors for classification of each of the pixels into one of L classification classes. And, images presenting color chromosomes.

    215.
    发明专利
    失效

    公开(公告)号：JP2002530676A

    公开(公告)日：2002-09-17

    申请号：JP2000584297

    申请日：1999-11-16

    IPC: C12Q1/68 ,  C12Q1/6841 ,  C12Q1/6883 ,  G01J3/02 ,  G01J3/12 ,  G01J3/26 ,  G01J3/28 ,  G01J3/44 ,  G01J3/453 ,  G01N1/30 ,  G01N21/64 ,  G01N21/78 ,  G01N33/50 ,  G01N33/53 ,  G01N33/533 ,  G01N33/535 ,  G01N33/569 ,  G01N33/58 ,  G06K9/00 ,  G06K9/76

    Abstract: A method of in situ analysis of a biological sample comprising the steps of (a) staining the biological sample with N stains of which a first stain is selected from the group consisting of a first immunohistochemical stain, a first histological stain and a first DNA ploidy stain, and a second stain is selected from the group consisting of a second immunohistochemical stain, a second histological stain and a second DNA ploidy stain, with provisions that N is an integer greater than three and further that (i) if the first stain is the first immunohistochemical stain then the second stain is either the second histological stain or the second DNA ploidy stain; (ii) if the first stain is the first histological stain then the second stain is either the second immunohistochemical stain or the second DNA ploidy stain; whereas (iii) if the first stain is the first DNA ploidy stain then the second stain is either the second immunohistochemical stain or the second histological stain; and (b) using a spectral data collection device for collecting spectral data from the biological sample, the spectral data collection device and the N stains are selected such that a spectral component associated with each of the N stains is collectable.

    216.
    发明专利
    失效

    公开(公告)号：JP2002511942A

    公开(公告)日：2002-04-16

    申请号：JP50728299

    申请日：1998-06-29

    IPC: G01J3/28 ,  C12Q1/68 ,  G01J3/02 ,  G01J3/12 ,  G01J3/26 ,  G01J3/44 ,  G01J3/453 ,  G01N21/64 ,  G01N33/50 ,  G01N33/569 ,  G01N33/58 ,  G06K9/00 ,  G06K9/76 ,  G06T1/00

    Abstract: A method for remote scenes classification comprising the steps of (a) preparing a reference template for classification of the remote scenes via (i) classifying a set of reference scenes via a conventional classification technique for obtaining a set of preclassified reference scenes; (ii) using a first spectral imager for measuring a spectral cube of the preclassified reference scenes; (iii) employing a principal component analysis for extracting the spectral cube for decorrelated spectral data characterizing the reference scenes; and (vi) using at least a part of the decorrelated spectral data for the preparation of the reference template for remote scenes classification; (b) using a second spectral imager for measuring a spectral cube of analyzed remote scenes, such that a spectrum of each pixel in the remote scenes is obtained; (c) employing a decorrelation statistical method for extracting decorrelated spectral data characterizing the pixels; and (d) comparing at least a part of the decorrelated spectral data extracted from the pixels of the remote scenes with the reference template.

    218.
    发明专利
    失效

    公开(公告)号：JP2001517521A

    公开(公告)日：2001-10-09

    申请号：JP2000513500

    申请日：1998-09-29

    IPC: A61B3/11 ,  A61B3/12 ,  A61B5/00 ,  C12Q1/68 ,  G01J3/02 ,  G01J3/12 ,  G01J3/26 ,  G01J3/28 ,  G01J3/44 ,  G01J3/453 ,  G01N21/64 ,  G01N33/50 ,  G01N33/569 ,  G01N33/58 ,  G06K9/00 ,  G06K9/76

    Abstract: A spectral bio-imaging method for enhancing pathologic, physiologic, metabolic and health related spectral signatures of an eye tissue, the method comprising the steps of (a) providing an optical device for eye inspection being optically connected to a spectral imager; (b) illuminating the eye tissue with light via the iris, viewing the eye tissue through the optical device and spectral imager and obtaining a spectrum of light for each pixel of the eye tissue; and (c) attributing each of the pixels a color or intensity according to its spectral signature, thereby providing an image enhancing the spectral signatures of the eye tissue.

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