公开(公告)号：US20110080581A1

公开(公告)日：2011-04-07

申请号：US12900172

申请日：2010-10-07

Applicant: Rohit Bhargava ,  Brian T. Cunningham

Inventor： Rohit Bhargava ,  Brian T. Cunningham

IPC: G01J3/28 ,  G01J3/40

CPC classification number: G01J3/12 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0275 ,  G01J3/0286 ,  G01J3/0289 ,  G01N21/35

Abstract: Described herein are spectrometers comprising one or more wavelength-selective filters, such as guided mode resonance filters. Some of the spectrometers described herein are configured for obtaining absorbance spectra in a discrete fashion by measuring absorbances of a sample at multiple discrete wavelengths or wavelength bands. In another aspect, methods are also provided for obtaining spectra, images and chemical maps of samples in a discrete fashion.

Abstract translation: 这里描述的是包括一个或多个波长选择滤光器的光谱仪，例如导模谐振滤波器。 这里描述的一些光谱仪被配置为通过测量在多个离散波长或波长带上的样品的吸光度以离散的方式获得吸收光谱。 在另一方面，还提供了用于以离散方式获得样品的光谱，图像和化学图谱的方法。

公开(公告)号：US07577064B2

公开(公告)日：2009-08-18

申请号：US11456610

申请日：2006-07-11

Applicant: Robert Marsche ,  Wolfgang Fuchs ,  Harald Gebetsroither

Inventor： Robert Marsche ,  Wolfgang Fuchs ,  Harald Gebetsroither

IPC: G11B7/00 ,  G01J1/10

CPC classification number: G01J3/12 ,  G01J3/02 ,  G01J3/027 ,  G01J3/0275 ,  G01J2003/1217 ,  G01N2021/317

Abstract: Microplate reader (21) with a computer for controlling the components of said microplate reader (21), comprising a light source (15) for emitting light for irradiating samples (22) or transmitting light through samples (22), and a filter slide (1) situated in the excitation or detection beam path. The microplate reader (21) in accordance with the invention is characterized in that said filter slide (1) comprises an electronic memory (4) for recording and/or retrieving filter-specific data, with said filter-specific data comprising the number and intensity of the light flashes impinging upon a certain filter (2) of said filter slide (1) and/or the intensity and duration of all exposures performed, and that said filter slide (1) comprises a contact point (5,7) jointly with the microplate reader (21) for transmitting such filter-specific data from the computer to the electronic memory (4) of the filter slide (1) and for retrieving such filter-specific data with the computer. According to the method in accordance with the invention for acquiring filter-specific data in a filter slide (1) of such a microplate reader (21), filter-specific data which comprise the number and intensity of the light flashes impinging upon a specific filter (2) of said filter slide (1) and/or the intensity and duration of all exposures performed are transmitted by the computer via a contact point common to said filter slide (1) and the microplate reader (21) to an electronic memory (4) of said filter slide (1) and/or are retrieved with the computer from said electronic memory (4).

Abstract translation: 一种用于控制所述微板读数器（21）的组件的计算机的微孔板读数器（21），包括用于发射用于照射样品（22）的光或者通过样品（22）透射光的光源（15） 1）位于激励或检测光束路径中。 根据本发明的酶标仪（21）的特征在于，所述过滤器滑块（1）包括用于记录和/或检索过滤器特定数据的电子存储器（4），所述过滤器特定数据包括数量和强度 撞击在所述过滤器滑块（1）的某个过滤器（2）上的闪光和/或所执行的所有曝光的强度和持续时间，并且所述过滤器滑块（1）包括与 所述微板读数器（21）用于将所述过滤器特定数据从所述计算机发送到所述过滤器滑板（1）的所述电子存储器（4）并且用所述计算机检索所述过滤器特定数据。 根据本发明的用于在这种酶标板读数器（21）的滤光片（1）中获得滤光器特定数据的方法，滤光器专用数据包括闪光的数量和强度，其冲击特定滤光片 （1）和/或所执行的所有曝光的强度和持续时间由计算机通过所述过滤板（1）和微板读数器（21）共同的接触点传送到电子存储器（ 4）和/或从所述电子存储器（4）用计算机检索。

公开(公告)号：US07555396B2

公开(公告)日：2009-06-30

申请号：US11086087

申请日：2005-03-22

Applicant: Lalit Keshav Mestha

Inventor： Lalit Keshav Mestha

IPC: G01D18/00

CPC classification number: G01J3/50 ,  G01J3/02 ,  G01J3/0275 ,  G01J3/501 ,  G01J3/524

Abstract: To generate a reference database for a particular sensor in a multiple LED spectrophotometric system with a reduced number of test measurements taken from training samples, a first set of reflectance reference measurements are generated from a test target on to a reference sensor from a plurality of different LED emissions. A first spectral reconstruction reference matrix is computed by performing an operational characterization of the reference sensor from the first set of reflectance reference measurements. A second set of reflectance reference measurements from the test target is generated from a second subject sensor whose operation is to be personalized by the objective reference database. The second set of reflectance reference measurements are less in number than the first set. A second reconstruction matrix is computed by performing an operational characterization of the subject sensor from the second set of measurements. The second reconstruction matrix is adjusted by relating the second set of reflectance measurements to a set of corresponding reflectance measurements of the reference sensor, whereby the adjusting of the second matrix comprises computing an optimal solution spectral reconstruction matrix for the second sensor. The reference database is generated from the optimal solution spectral reconstruction matrix.

Abstract translation: 为了在具有从训练样本获得的测试测量数量减少的多个LED分光光度系统中产生用于特定传感器的参考数据库，从测试目标产生第一组反射参考测量值到多个不同的参考传感器 LED排放。 通过从第一组反射参考测量值执行参考传感器的操作表征来计算第一光谱重构参考矩阵。 来自测试目标的第二组反射参考测量从第二目标传感器产生，其第二对象传感器的操作将由目标参考数据库进行个性化。 第二组反射参考测量数量少于第一组。 通过从第二组测量执行对象传感器的操作表征来计算第二重建矩阵。 通过将第二组反射率测量值与参考传感器的一组对应的反射率测量值相关联来调整第二重构矩阵，由此第二矩阵的调整包括计算第二传感器的最优解谱重构矩阵。 参考数据库是从最优解谱重建矩阵生成的。

公开(公告)号：US07526328B2

公开(公告)日：2009-04-28

申请号：US11640077

申请日：2006-12-15

Applicant: Mohamed Kheir Diab ,  Massi E. Kiani ,  Charles Robert Ragsdale ,  James M. Lepper, Jr.

Inventor： Mohamed Kheir Diab ,  Massi E. Kiani ,  Charles Robert Ragsdale ,  James M. Lepper, Jr.

IPC: A61B5/1455

CPC classification number: A61B5/1495 ,  A61B5/0205 ,  A61B5/02427 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  A61B2562/08 ,  G01J3/02 ,  G01J3/0254 ,  G01J3/027 ,  G01J3/0275 ,  G01J3/0291 ,  G01J3/10 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3151 ,  G01N21/39 ,  G01N2021/3144 ,  G01N2201/0627

Abstract: Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like. In one preferred embodiment, coding resistors could be provided across the light sources to allow additional information about the probe to be coded without added leads. However, any device could be used without it being used in parallel.

Abstract translation: 本公开的实施例还包括能够向身体组织衰减之后除了表示光强度的信号之外，向患者监视器传送识别信息的光学探针。 识别信息可以指示光源的操作波长，指示探针的类型，例如探针是成人探针，儿科探针，新生儿探针，一次性探针，可重复使用的探针等 。 该信息也可以用于安全目的，例如，以确保探针被适当地配置用于血氧计，以指示探针来自授权供应商等。 在一个优选实施例中，编码电阻器可以跨越光源提供，以允许关于探针的附加信息被编码而没有添加引线。 但是，任何设备都可以在没有并行使用的情况下使用。

公开(公告)号：US20070188764A1

公开(公告)日：2007-08-16

申请号：US11504187

申请日：2006-08-15

Applicant: Jon Nisper ,  Michael Mater ,  Bernard Berg

Inventor： Jon Nisper ,  Michael Mater ,  Bernard Berg

IPC: G01N21/47

CPC classification number: G01J3/10 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0275 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/26 ,  G01J3/28 ,  G01J3/50 ,  G01J3/501 ,  G01J3/51 ,  G01J3/513 ,  G01J3/524 ,  G01J2003/1213 ,  G01J2003/1282 ,  G01J2003/2866 ,  G01J2003/467

Abstract: An optical assembly for use with a spectrophotometer. The optical assembly may comprise an illumination source, a detection sensor, a monitor sensor, and an optical piece having a first side adapted to face a sample. The optical piece may define an illumination channel extending from the illumination source toward the first side. The optical piece may also define a detection channel extending from the first side toward the detection sensor. In addition, the optical piece may define a monitor channel extending from the illumination channel toward the monitor sensor. Also, a light emitting diode (LED) assembly for use with an optical measurement device. The LED assembly may comprise a substrate having a top surface and a bottom surface and a plurality of LED dies positioned on the substrate to emit light in a first direction normal to the bottom surface of the substrate. The LED assembly may also comprise a plurality of leads in electrical contact with the plurality of LED dies. The plurality of leads may be positioned on the bottom surface of the substrate, and may be configured to surface-mount to a board.

Abstract translation: 用于分光光度计的光学组件。 光学组件可以包括照明源，检测传感器，监视器传感器和具有适于面向样品的第一侧的光学片。 光学片可以限定从照明源向第一侧延伸的照明通道。 光学片还可以限定从第一侧向检测传感器延伸的检测通道。 此外，光学片可以限定从照明通道延伸到监视器传感器的监视器通道。 另外，与光学测量装置一起使用的发光二极管（LED）组件。 LED组件可以包括具有顶表面和底表面的衬底和位于衬底上的多个LED管芯，以在垂直于衬底的底表面的第一方向上发光。 LED组件还可以包括与多个LED管芯电接触的多个引线。 多个引线可以定位在基板的底表面上，并且可以被配置为表面安装到基板。

公开(公告)号：US20070112260A1

公开(公告)日：2007-05-17

申请号：US11640077

申请日：2006-12-15

Applicant: Mohamed Diab ,  Massi Kiani ,  Charles Ragsdale ,  James Lepper

Inventor： Mohamed Diab ,  Massi Kiani ,  Charles Ragsdale ,  James Lepper

IPC: A61B5/00

CPC classification number: A61B5/1495 ,  A61B5/0205 ,  A61B5/02427 ,  A61B5/14552 ,  A61B5/6826 ,  A61B5/6838 ,  A61B2562/08 ,  G01J3/02 ,  G01J3/0254 ,  G01J3/027 ,  G01J3/0275 ,  G01J3/0291 ,  G01J3/10 ,  G01J2003/2866 ,  G01N21/255 ,  G01N21/274 ,  G01N21/31 ,  G01N21/3151 ,  G01N21/39 ,  G01N2021/3144 ,  G01N2201/0627

Abstract: Embodiments of the present disclosure include an optical probe capable of communicating identification information to a patient monitor in addition to signals indicative of intensities of light after attenuation by body tissue. The identification information may indicate operating wavelengths of light sources, indicate a type of probe, such as, for example, that the probe is an adult probe, a pediatric probe, a neonatal probe, a disposable probe, a reusable probe, or the like. The information could also be utilized for security purposes, such as, for example, to ensure that the probe is configured properly for the oximeter, to indicate that the probe is from an authorized supplier, or the like. In one preferred embodiment, coding resistors could be provided across the light sources to allow additional information about the probe to be coded without added leads. However, any device could be used without it being used in parallel.

Abstract translation: 本公开的实施例还包括能够向身体组织衰减之后除了表示光强度的信号之外，向患者监视器传送识别信息的光学探针。 识别信息可以指示光源的操作波长，指示探针的类型，例如探针是成人探针，儿科探针，新生儿探针，一次性探针，可重复使用的探针等 。 该信息也可以用于安全目的，例如，以确保探针被适当地配置用于血氧计，以指示探针来自授权供应商等。 在一个优选实施例中，编码电阻器可以跨越光源提供，以允许关于探针的附加信息被编码而没有添加引线。 但是，任何设备都可以在没有并行使用的情况下使用。

公开(公告)号：US20070061111A1

公开(公告)日：2007-03-15

申请号：US11475717

申请日：2006-06-26

Applicant: Wayne Jung ,  Russell Jung ,  Alan Loudermilk

Inventor： Wayne Jung ,  Russell Jung ,  Alan Loudermilk

IPC: G06F11/00

CPC classification number: G01J3/02 ,  G01J1/0411 ,  G01J1/0437 ,  G01J1/0474 ,  G01J1/06 ,  G01J1/44 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0251 ,  G01J3/0259 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0275 ,  G01J3/0278 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/46 ,  G01J3/463 ,  G01J3/508 ,  G01J3/51 ,  G01J3/513

Abstract: Optical characteristic measuring systems and methods such as for determining the color or other optical characteristics of teeth are disclosed. Perimeter receiver fiber optics preferably are spaced apart from a source fiber optic and receive light from the surface of the object/tooth being measured. Light from the perimeter fiber optics pass to a variety of filters. The system utilizes the perimeter receiver fiber optics to determine information regarding the height and angle of the probe with respect to the object/tooth being measured. Under processor control, the optical characteristics measurement may be made at a predetermined height and angle. Various color spectral photometer arrangements are disclosed. Translucency, fluorescence, gloss and/or surface texture data also may be obtained. Audio feedback may be provided to guide operator use of the system. The probe may have a removable or shielded tip for contamination prevention. A method of producing dental prostheses based on measured data also is disclosed. Measured data also may be stored and/or organized as part of a patient data base. Such methods and implements may be desirably utilized for purposes of detecting and preventing counterfeiting or the like.

Abstract translation: 公开了用于确定牙齿的颜色或其他光学特性的光学特性测量系统和方法。 周边接收机光纤优选地与源光纤间隔开，并且从被测量的物体/齿的表面接收光。 来自周边光纤的光通过各种滤光片。 该系统利用周边接收器光纤来确定关于探头相对于所测量的物体/齿的高度和角度的信息。 在处理器控制下，可以以预定的高度和角度进行光学特性测量。 公开了各种颜色光谱光度计布置。 也可以获得半透明度，荧光，光泽度和/或表面纹理数据。 可以提供音频反馈以指导操作者使用该系统。 探头可能具有可移除或屏蔽的尖端，以防止污染。 还公开了一种基于测量数据生产牙科假体的方法。 测量的数据也可以存储和/或组织为患者数据库的一部分。 为了检测和防止伪造等目的，可以期望地使用这些方法和装置。

公开(公告)号：US20030117628A1

公开(公告)日：2003-06-26

申请号：US09947569

申请日：2001-09-07

Inventor： Raimo Harju ,  Markku Varjonen

IPC: G01N021/25

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0275 ,  G01N21/253 ,  G01N35/00623 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2035/00683 ,  G01N2035/00811

Abstract: The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to more reliable, intelligent instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invention is achieved by providing an optical measurement instrument where a selectable optical component is identified by the measurement instrument. The instrument therefore has means for identifying an optical component by e.g. reading a code from the component. The object is also achieved by a changeable/selectable optical component such as optical module or filter for a measurement instrument, the component comprising a readable identification means. The identification comprises information on the type/properties of the optical component so that the components suitability for a selected measurement can be verified.

Abstract translation: 本发明一般涉及生化实验室领域。 更具体地，本发明涉及用作例如设备的更可靠的智能仪器特征。 荧光计，光度计和光度计。 本发明的目的是通过提供一种光学测量仪器来实现，其中由测量仪器识别可选择的光学部件。 因此，该仪器具有用于通过例如用于识别光学部件的装置。 从组件读取代码。 该目的还通过可变/可选择的光学部件来实现，例如用于测量仪器的光学模块或滤光器，该部件包括可读识别装置。 识别包括关于光学部件的类型/性质的信息，使得可以验证对于所选择的测量的部件适用性。

公开(公告)号：US20010030748A1

公开(公告)日：2001-10-18

申请号：US09872039

申请日：2001-06-01

Inventor： Wayne D. Jung ,  Russell W. Jung ,  Alan R. Loudermilk

IPC: G01J003/51

CPC classification number: G01J3/02 ,  G01J1/0411 ,  G01J1/0437 ,  G01J1/0474 ,  G01J1/06 ,  G01J1/44 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/0229 ,  G01J3/0251 ,  G01J3/0259 ,  G01J3/0264 ,  G01J3/027 ,  G01J3/0275 ,  G01J3/0278 ,  G01J3/0283 ,  G01J3/0291 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/46 ,  G01J3/463 ,  G01J3/508 ,  G01J3/51 ,  G01J3/513

Abstract: Optical characteristic measuring systems and methods such as for determining the color or other optical characteristics of teeth are disclosed. Perimeter receiver fiber optics preferably are spaced apart from a source fiber optic and receive light from the surface of the object/tooth being measured. Light from the perimeter fiber optics pass to a variety of filters. The system utilizes the perimeter receiver fiber optics to determine information regarding the height and angle of the probe with respect to the object/tooth being measured. Under processor control, the optical characteristics measurement may be made at a predetermined height and angle. Various color spectral photometer arrangements are disclosed. Translucency, fluorescence, gloss and/or surface texture data also may be obtained. Audio feedback may be provided to guide operator use of the system. The probe may have a removable or shielded tip for contamination prevention. A method of producing dental prostheses based on measured data also is disclosed. Measured data also may be stored and/or organized as part of a patient data base. Such methods and implements may be desirably utilized for purposes of detecting and preventing counterfeiting or the like.

Abstract translation: 公开了用于确定牙齿的颜色或其他光学特性的光学特性测量系统和方法。 周边接收机光纤优选地与源光纤间隔开，并且从被测量的物体/齿的表面接收光。 来自周边光纤的光通过各种滤光片。 该系统利用周边接收器光纤来确定关于探头相对于所测量的物体/齿的高度和角度的信息。 在处理器控制下，可以以预定的高度和角度进行光学特性测量。 公开了各种颜色光谱光度计布置。 也可以获得半透明度，荧光，光泽度和/或表面纹理数据。 可以提供音频反馈以指导操作者使用该系统。 探头可能具有可移除或屏蔽的尖端，以防止污染。 还公开了一种基于测量数据生产牙科假体的方法。 测量的数据也可以存储和/或组织为患者数据库的一部分。 为了检测和防止伪造等目的，可以期望地使用这些方法和装置。