公开(公告)号：WO1993007803A1

公开(公告)日：1993-04-29

申请号：PCT/US1992008801

申请日：1992-10-21

Applicant: CYBERONICS, INC.

Inventor： CYBERONICS, INC. ,  BAKER, Ross, G., Jr.

IPC: A61B05/04

CPC classification number: A61N1/0556

Abstract: A nerve electrode array includes one or more Y-shaped carriers (10) in which the three legs of the Y are curled about a common axis with the lower leg (15) of the Y oppositely directed relative to the other two (12, 13) so that the legs will encircle a nerve substantially sharing the common axis, and a flexible electrode (17) secured to the underside of at least one of the legs.

公开(公告)号：WO1992021285A1

公开(公告)日：1992-12-10

申请号：PCT/US1992003142

申请日：1992-04-16

Applicant: EP TECHNOLOGIES, INC.

Inventor： EP TECHNOLOGIES, INC. ,  EDWARDS, Stuart, D. ,  FRANZ, Michael, R. ,  THOMPSON, Russell, B. ,  STERN, Roger, A.

IPC: A61B05/04

CPC classification number: A61B18/1206 ,  A61B5/0422 ,  A61B18/12 ,  A61B18/1492 ,  A61B2017/00292 ,  A61B2017/003 ,  A61B2017/00473 ,  A61B2018/00107 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/0066 ,  A61B2018/00839 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1495 ,  A61B2018/1497 ,  A61B2018/162 ,  A61B2562/0215 ,  A61N1/056

Abstract: A combination catheter for both detecting monophasic action potentials and ablating surface tissue in an in vivo heart of a patient is provided. The apparatus includes a catheter probe having a terminal tip portion (10) and an electrode (20) carried on the tip such that a portion of the tip electrode (20) is exposed to ambient. A reference electrode (50) is spaced along the tip from the first electrode for supplying a reference potential signal. An ablating electrode (30) is located adjacent to but electrically insulated from both the tip (20) and reference (50) electrodes for providing electromagnetic energy to the tip. The electrodes are electrically connected to the proximal end of the catheter through individual conductors or wires (22, 32, and 50) that run through an insulated cable. An electronic filter is provided to permit the recording of MAPs during ablation without radiofrequency interference. The catheter may also include standard mapping and/or pacing electrodes (80 and 75) respectively. The catheter may further include a steering mechanism for positioning the catheter at various treatment sites in the heart, and a structure for holding the tip electrode in substantially perpendicular contact with heart tissue with a positive pressure, and for spacing the reference electrode from the heart tissue.

Abstract translation: 提供了用于检测患者的体内心脏中的单相动作电位和消融表面组织的组合导管。 该装置包括导管探头，其具有端子末端部分（10）和承载在尖端上的电极（20），使得尖端电极（20）的一部分暴露于环境中。 参考电极（50）沿着尖端与第一电极间隔开，用于提供参考电位信号。 烧蚀电极（30）位于与尖端（20）和参考电极（50）电极相邻但电绝缘的位置，用于向尖端提供电磁能。 电极通过穿过绝缘电缆的单个导体或导线（22,32和50）电连接到导管的近端。 提供电子滤波器以允许在消融期间MAP的记录而没有射频干扰。 导管还可以分别包括标准贴图和/或起搏电极（80和75）。 导管还可以包括用于将导管定位在心脏中的各种治疗部位的转向机构，以及用于将尖端电极与正常压力基本上垂直接触心脏组织并将参考电极与心脏组织间隔开的结构 。

公开(公告)号：WO1992015242A1

公开(公告)日：1992-09-17

申请号：PCT/EP1992000473

申请日：1992-03-04

Applicant: SIEMENS-ELEMA AB ,  SIEMENS AKTIENGESELLSCHAFT ,  LUNDSTRÖM, Lena ,  KARLSSON, Peter ,  OHLSSON, Thomas

Inventor： SIEMENS-ELEMA AB ,  SIEMENS AKTIENGESELLSCHAFT

IPC: A61B05/04

CPC classification number: A61B5/04017 ,  A61B5/04004

Abstract: In the prior art, methods for filtering out baseline fluctuations from an electrocardiogram exist which use a high-pass filter whose lower cut-off frequency is below that characteristic of heart signals at the lowest-possible heartbeat rate. In order to increase the efficiency of the baseline filtering, the invention calls for the instantaneous heartbeat rate to be determined from the electrocardiogram by a device (4), and the lower cut-off frequency of the filter (2) to be modified as a function of the result of this determination in such a way that the lower cut-off frequency is increased with increasing heartbeat rate and is decreased with decreasing hearbeat rate.

公开(公告)号：WO1992010134A1

公开(公告)日：1992-06-25

申请号：PCT/SE1991000822

申请日：1991-12-03

Applicant: KNUTSSON, Evert ,  GRANSBERG, Lennart

IPC: A61B05/04

CPC classification number: A61B5/0488 ,  A61B5/407

Abstract: The invention relates to apparatus which includes stimulating electrodes (2, 3) through which electrical signals are applied to an extremity of a patient (1). Detecting electrodes (30, 40) are disposed along the patient's spine and on the crown of the patient's head. The apparatus also includes signal amplifiers (7, 8), a loudspeaker (9) or the like to which an amplified signal is applied for physiological feedback purposes, an A/D-converter and a computer (20). Samples of signals are collected so as to obtain from the distributed electrodes means value curves from which the transport time of the nerve signals from respective extremities can be determined.

Abstract translation: 本发明涉及包括刺激电极（2,3）的装置，通过电极将电信号施加到患者（1）的末端。 检测电极（30,40）沿患者的脊柱和患者头部的冠部设置。 该装置还包括信号放大器（7,8），扬声器（9）等，放大的信号用于生理反馈目的，A / D转换器和计算机（20）。 收集信号样本以从分布电极获得意味着可以确定来自各个末端的神经信号的运输时间的值曲线。

公开(公告)号：WO1992004862A1

公开(公告)日：1992-04-02

申请号：PCT/DE1991000731

申请日：1991-09-16

Applicant: SIEMENS AKTIENGESELLSCHAFT ,  HASSLER, Dietrich ,  REICHENBERGER, Helmut ,  TEMME, Günter

Inventor： SIEMENS AKTIENGESELLSCHAFT

IPC: A61B05/04

CPC classification number: A61B5/04005 ,  A61B8/0833

Abstract: A process for the anatomically locally correct allocation of the excitation centres of biomagnetic comprises the following steps: the excitation centres of the biomagnetic signals found with the aid of a biomagnetic measuring system are in a first system of co-ordinates (Km); the image signals obtained with an ultrasonic applicator (4) are in a second system of co-ordinates (Ku); marking points (8) lie in the examination region or on a surface of the examination region accessible to the ultrasonic applicator (4) the position of which in both systems of co-ordinates (Km, Ku) is known, the two systems of co-ordinates (Km, Ku) are mutually moved sothat all the marking points (8) are superimposed; each excitation centre is indicated by a symbol on the ultrasonic image. If the position of the examination region is unchanged on the provision of the image signals from that on finding the excitation points, it is sufficient with a fixed arrangement of the two systems of co-ordinates (Km, Ku), to calibrate one of them (e.g. Ku) in relation to the other (e.g. Km). Marking points are then superfluous.

公开(公告)号：WO1991015994A1

公开(公告)日：1991-10-31

申请号：PCT/US1991002520

申请日：1991-04-12

Applicant: AD-TECH MEDICAL INSTRUMENT CORPORATION

Inventor： AD-TECH MEDICAL INSTRUMENT CORPORATION ,  PUTZ, David, A.

IPC: A61B05/04

CPC classification number: A61B5/6852 ,  A61B5/04001 ,  A61B5/0422 ,  A61B5/4094 ,  A61B2562/0209 ,  A61B2562/043 ,  A61B2562/046 ,  G01R33/28 ,  G01R33/58

Abstract: An improved intracranial diagnostic electrode (10) for use with magnetic resonance imaging techniques includes an electrode body (16) and at least one metallic contact (11) supported by the body (16). An electrical lead wire (19) is attached to the contact (11) for connecting the contact (11) to a diagnostic instrument. At least the metallic contact (11) is made of an alloy which includes nickel and chronium and is substantially devoid of iron. The electrode (10) thereby provides substantially clear images of the location of each metallic contact (11) when the electrode is used in conjunction with magnetic resonance imaging techniques. The electrode (10) may also include radiopaque elements (25) or markers to adapt the electrode (10) for use with x-ray as well as magnetic resonance imaging techniques. Several embodiments are disclosed.

公开(公告)号：WO1991003203A1

公开(公告)日：1991-03-21

申请号：PCT/US1990005017

申请日：1990-09-05

Applicant: NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. ,  DUKE UNIVERSITY ,  THE BOARD OF REGENTS OF THE UNIVERSITY OF ...

Inventor： NEW ENGLAND MEDICAL CENTER HOSPITALS, INC. ,  DUKE UNIVERSITY ,  THE BOARD OF REGENTS OF THE UNIVERSITY OF ... ,  SELKER, Harry, P. ,  WEAVER, Douglas, W. ,  WAGNER, Galen, S. ,  CALIFF, Robert, M.

IPC: A61B05/04

CPC classification number: A61B5/0452 ,  A61B5/021 ,  A61B5/024 ,  A61B5/4839 ,  A61B5/7275 ,  G06F19/00 ,  G16H50/30

Abstract: An instrument for predicting the benefit of using thrombolytic therapy to treat a patient with a heart condition including a first input port for receiving inputs derived from electrocardiograph measurements of the patient's condition, and a processor for computing an estimate of said benefit based upon the electrocardiograph-derived inputs.

公开(公告)号：WO1991002484A1

公开(公告)日：1991-03-07

申请号：PCT/US1990001385

申请日：1990-03-13

Applicant: BIOMETRAK CORPORATION

Inventor： BIOMETRAK CORPORATION ,  CHAMOUN, Nassib, G.

IPC: A61B05/04

CPC classification number: A61B5/044 ,  A61B5/0452 ,  A61B5/04525 ,  A61B5/0464 ,  A61B5/413 ,  A61B5/7257 ,  A61B5/7275 ,  G06F19/00

Abstract: Patient leads (101) are connected to a patient (100) and ECG signals are picked up by the leads and transmitted over a patient cable (102) to a 16-channel ECG data acquisition system (104) with a serial interface. The data acquisition system (104) filters, amplifies and digitizes the ECG waveforms and sends the digitized data to a microcomputer (110) via a high speed synchronous serial line (106). The microcomputer (110) processes the serial data stream in order to generate computed data arrays. These arrays are then used in conjunction with predetermined reference arrays to produce diagnostic indices. These indices are displayed on the graphics display (108). Printed output is available on the hard copy output device (116) which is connected to the microcomputer (110). Interaction between the operator and the system is provided by means of a keyboard (112) and pointing device (114) with feedback on the graphics display (108).

Abstract translation: 患者导线（101）连接到患者（100），ECG信号由引线拾取并通过患者电缆（102）传送到具有串行接口的16通道ECG数据采集系统（104）。 数据采集​​系统（104）对ECG波形进行滤波，放大和数字化，并通过高速同步串行线路（106）将数字化数据发送到微计算机（110）。 微计算机（110）处理串行数据流以生成计算的数据阵列。 然后将这些阵列与预定的参考阵列结合使用以产生诊断索引。 这些指标显示在图形显示器（108）上。 在连接到微计算机（110）的硬拷贝输出装置（116）上提供打印输出。 通过在图形显示器（108）上具有反馈的键盘（112）和指点设备（114）来提供操作者和系统之间的相互作用。

公开(公告)号：WO1989011821A1

公开(公告)日：1989-12-14

申请号：PCT/JP1989000554

申请日：1989-06-01

Applicant: MEDICAL INSTRUMENT JAPAN CO., LTD. ,  UEDA, Morikazu ,  TAKAHASHI, Sadatsugu ,  OHARA, Youitsu

Inventor： MEDICAL INSTRUMENT JAPAN CO., LTD.

IPC: A61B05/04

CPC classification number: A61B5/0452 ,  A61B5/0432

Abstract: A portable apparatus for recording and analyzing electrocardiogram comprises means for counting the sum of P, Q, R, S, T and U waves that are greater than a setpoint reference voltage of ECG waves for every predetermined period of time, means for storing the previously counted value, means for setting a reference value of difference between the above two means, signal means which produces a signal when the difference between the counted value of said counting means and the stored value of said storage means is greater than a predetermined value, recording means for recording ECG waves during any discrete time, and means which, when said signal means produces an output, stores the ECG waveforms at that moment together with the ECG waveforms of the preceding stage. The apparatus is adapted to monitoring patients who are treated for their disease of the heart and trouble in the brain, monitoring mentally and nervously diseased areas, monitoring patients who are being treated in a hospital or in their own homes, and monitoring the life of a severely wounded person.

Abstract translation: 用于记录和分析心电图的便携式装置包括用于对每个预定时间段大于ECG波的设定值参考电压的P，Q，R，S，T和U波的总和进行计数的装置，用于存储先前 计数值，用于设定上述两个装置之间的差值的参考值的装置，当所述计数装置的计数值与所述存储装置的存储值之间的差异大于预定值时产生信号的信号装置，记录 用于在任何离散时间期间记录ECG波的装置，以及当所述信号意味着产生输出时，将该时刻的ECG波形与前一级的ECG波形一起存储的装置。 该装置适用于监测患有心脏疾病和大脑疾病的患者，监测精神和紧张的患病区域，监测在医院或家中接受治疗的患者以及监测患者的生命 严重受伤的人。

公开(公告)号：WO1989011819A1

公开(公告)日：1989-12-14

申请号：PCT/GB1989000631

申请日：1989-06-07

Applicant: SURGICRAFT LIMITED ,  BAND, David, Marston ,  PENMAN, David, Gerard

Inventor： SURGICRAFT LIMITED

IPC: A61B05/04

CPC classification number: A61B5/4362 ,  A61B5/0448 ,  Y10T29/49117 ,  Y10T29/49204

Abstract: A low resistance electrical pick-up, such as a fetal scalp electrode (17), comprises a stainless steel wire (10), with an arcuate needle (18) on the outer end of a radial arm (19), the arcuate needle (18) being plated with nickel (14) and then silver (15), optionally with an intervening layer of copper (16), and then an area (11) of the silver layer (15) at least on the outside of the curve of the needle (18), and possibly spaced from the point of the needle, is chloridized and then coated with bio-compatible plastics (12).

Abstract translation: 诸如胎儿头皮电极（17）的低电阻拾取器包括不锈钢丝（10），在径向臂（19）的外端上具有弓形针（18），弓形针 18）镀镍（14）然后镀银（15），任选地具有铜（16）的中间层，然后至少在银层（15）的曲线外侧上的区域（11） 针（18）并且可能与针的间隔开，被氯化，然后用生物相容性塑料（12）涂覆。