公开(公告)号：US20160033408A1

公开(公告)日：2016-02-04

申请号：US14425465

申请日：2014-08-08

Applicant: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.

Inventor： Kenji NARUMI

IPC: G01N21/64

CPC classification number: G01N21/648 ,  G01N2201/06113 ,  G01N2201/0683

Abstract: The present application discloses a detecting apparatus including: a light source for emitting excitation light; a storage portion in which a specimen is stored; a metal film which receives the excitation light to cause evanescent light for illuminating the specimen; a modulator for adjusting an incident angle of the excitation light on the metal film; a driver for generating a driving signal for driving the modulator; a detector for outputting a fluorescence signal in correspondence to intensity of fluorescence generated from the specimen under irradiation of the evanescent light; and an extractor which extracts a signal component from the fluorescence signal, the signal component deriving from the specimen. The incident angle changes in response to a change of the driving signal. The extractor extracts a synchronous signal component as the signal component, the synchronous signal component changing in synchronization with the change of the driving signal.

Abstract translation: 本申请公开了一种检测装置，包括：用于发射激发光的光源; 存储部，其中存储有试样; 接收激发光以引起ev逝光照射样品的金属膜; 用于调节所述金属膜上的激发光的入射角的调制器; 用于产生用于驱动调制器的驱动信号的驱动器; 检测器，用于输出与所述ev逝光照射下从样本产生的荧光强度对应的荧光信号; 以及从所述荧光信号中提取信号成分的提取器，所述信号成分来自所述样本。 入射角随着驾驶信号的变化而变化。 提取器提取同步信号分量作为信号分量，同步信号分量与驱动信号的变化同步地改变。

公开(公告)号：US20150342507A1

公开(公告)日：2015-12-03

申请号：US14822524

申请日：2015-08-10

Applicant: K Sciences GP, LLC

Inventor： Valentin Korman

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/00 ,  G01N21/21

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/6815 ,  A61B5/7225 ,  A61B2560/0443 ,  A61B2562/0238 ,  G01N21/21 ,  G01N2201/062 ,  G01N2201/0683

Abstract: A glucose sensor comprising an optical energy source having an emitter with an emission pattern; a first polarizer intersecting the emission pattern; a second polarizer spaced a distance from the first polarizer and intersecting the emission pattern, the second polarizer rotated relative to the first polarizer by a first rotational amount Θ; a first optical detector intersecting the emission pattern; a second optical detector positioned proximal to the second polarizer, the first polarizer and the second polarizer being positioned between the optical energy source and the second optical detector, the second optical detector intersecting the emission pattern; a compensating circuit coupled to the second optical detector; and a subtractor circuit coupled to the compensating circuit and the first optical detector.

Abstract translation: 一种葡萄糖传感器，包括具有发射器的光能源，其具有发射图案; 与发射图案相交的第一偏振片; 与第一偏振器间隔开一定距离并与发射图案相交的第二偏振器，第二偏振器相对于第一偏振器相对于第一偏转器旋转第一旋转量Θ; 与发射图案相交的第一光学检测器; 位于第二偏振器附近的第二光学检测器，第一偏振器和第二偏振器位于光能源和第二光学检测器之间，第二光学检测器与发射图案相交; 耦合到所述第二光学检测器的补偿电路; 以及耦合到所述补偿电路和所述第一光学检测器的减法器电路。

公开(公告)号：US20150308950A1

公开(公告)日：2015-10-29

申请号：US14694098

申请日：2015-04-23

Applicant: The Chinese University of Hong Kong ,  City University of Hong Kong

Inventor： Ho Pui Ho ,  Shu Yuen Wu ,  Chi-Man Lawrence Wu ,  Siu Pang Ng ,  Siu Kai Kong

IPC: G01N21/552 ,  G01B9/02

CPC classification number: G01N21/553 ,  G01N21/45 ,  G01N2201/0683

Abstract: An optical sensing apparatus and a method for detecting characteristics of a sample.

Abstract translation: 一种用于检测样品特性的光学感测装置和方法。

公开(公告)号：US20150253243A1

公开(公告)日：2015-09-10

申请号：US14432066

申请日：2013-09-27

Applicant: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE

Inventor： Hyun Mo Cho ,  Yong Jai Cho ,  Won Chegal

IPC: G01N21/21 ,  G01N21/41

CPC classification number: G01N21/211 ,  G01N21/05 ,  G01N21/253 ,  G01N21/41 ,  G01N2201/06113 ,  G01N2201/0683

Abstract: An apparatus and method for simultaneously measuring, in an immersion microchannel environment, the characteristics of molecular junctions such as a low-molecular-weight biomaterial and the like and the refractive index of a buffer solution by using ellipsometry. Specifically, disclosed is an apparatus for simultaneously measuring, with high sensitivity, the change in refractive index of a buffer solution and the junction dynamic characteristics of a biomaterial by allowing polarized incident light to be received at a biomaterial adsorption layer, which is formed on a substrate such as a semiconductor and the like, so as to meet an anti-reflection condition of a P-wave by using a prism structure and a microchannel; and a measurement method using the same.

Abstract translation: 在浸入微通道环境中同时测量低分子量生物材料等分子结的特性以及使用椭偏仪测定缓冲溶液的折射率的装置和方法。 具体地说，公开了一种用于以高灵敏度同时测量缓冲溶液的折射率的变化和生物材料的结合动力学特性的装置，该方法是允许偏振的入射光被接收在生物材料吸附层上 基板如半导体等，以便通过使用棱镜结构和微通道来满足P波的抗反射条件; 以及使用其的测定方法。

公开(公告)号：US20150247808A1

公开(公告)日：2015-09-03

申请号：US14195656

申请日：2014-03-03

Applicant: COHERENT LASERSYSTEMS GMBH & CO. KG

Inventor： Paul VAN DER WILT

IPC: G01N21/95 ,  G02B21/00 ,  G01N21/88 ,  H01L21/66 ,  G01N21/84

CPC classification number: H01L21/67253 ,  C30B1/02 ,  C30B29/06 ,  G01N21/21 ,  G01N21/4788 ,  G01N21/8422 ,  G01N21/8851 ,  G01N21/9501 ,  G01N2021/8461 ,  G01N2021/8477 ,  G01N2201/06113 ,  G01N2201/068 ,  G01N2201/0683 ,  G01N2201/0697 ,  G01N2201/10 ,  G01N2201/105 ,  G02B21/002 ,  G02B21/0092 ,  H01L21/02532 ,  H01L21/02686 ,  H01L21/268 ,  H01L22/12

Abstract: A method is disclosed evaluating a silicon layer crystallized by irradiation with pulses form an excimer-laser. The crystallization produces periodic features on the crystalized layer dependent on the number of and energy density ED in the pulses to which the layer has been exposed. An area of the layer is illuminated with light. A microscope image of the illuminated area is made from light diffracted from the illuminated are by the periodic features. The microscope image includes corresponding periodic features. The ED is determined from a measure of the contrast of the periodic features in the microscope image.

Abstract translation: 公开了评估通过用脉冲照射形成准分子激光而结晶的硅层的方法。 结晶层上产生周期性特征，取决于层暴露于的脉冲中的数量和能量密度。 该层的一个区域用光照亮。 照明区域的显微镜图像由从被照明的周期特征衍射的光制成。 显微镜图像包括相应的周期特征。 ED是从显微镜图像中的周期特征的对比度的量度确定的。

公开(公告)号：US20150241360A1

公开(公告)日：2015-08-27

申请号：US14441856

申请日：2013-11-12

Applicant: FOCALSPEC OY

Inventor： Karri Niemela ,  Heimo Keranen

IPC: G01N21/90

CPC classification number: G01N21/9054 ,  G01N21/95 ,  G01N21/9508 ,  G01N2201/061 ,  G01N2201/0683

Abstract: A measuring apparatus (200) is provided for inspecting a seal (50) of an item (20). The measuring apparatus (200) includes a radiation source (510, 520) for providing radiation for illuminating the seal (50) of the item (20), a detector (530, 540) for receiving radiation from the item (20) for generating a corresponding detected signal, and a processing arrangement (160) for processing the detected signal to generate an output signal indicative of a state of the seal (50). The radiation source (510, 520) is arranged to focus the radiation into a plurality of focal points at the seal (50) of the item (20), wherein the focal points are mutually spatially spaced apart. Moreover, the detector (530, 540) is arranged to image one or more of the focal points and to be selectively sensitive to an intensity of radiation received from the one or more focal points to generate a detected signal. Furthermore, the measuring apparatus (200) includes a processing arrangement (160) for receiving the detected signal and for processing the detected signal to generate the output signal indicative of the state of the seal (50).

Abstract translation: 设置有用于检查物品（20）的密封件（50）的测量装置（200）。 测量装置（200）包括用于提供用于照射物品（20）的密封件（50）的辐射的辐射源（510,520），用于接收物品（20）的辐射的检测器（530,540），用于产生 相应的检测信号，以及处理装置（160），用于处理检测信号以产生指示密封状态的输出信号（50）。 辐射源（510,520）被布置成将辐射聚焦在物品（20）的密封件（50）处的多个焦点中，其中焦点在空间上相互间隔开。 此外，检测器（530,540）布置成对一个或多个焦点进行成像，并且对从一个或多个焦点接收的辐射强度选择性敏感以产生检测信号。 此外，测量装置（200）包括处理装置（160），用于接收检测到的信号并处理检测信号以产生指示密封状态的输出信号（50）。

公开(公告)号：US20150185135A1

公开(公告)日：2015-07-02

申请号：US14141602

申请日：2013-12-27

Applicant: Paul A. Martino

Inventor： Paul A. Martino

IPC: G01N21/21 ,  G01N21/01 ,  G01J4/00

CPC classification number: G01N21/211 ,  G01B11/0641 ,  G01N21/01 ,  G01N21/4133 ,  G01N2021/0106 ,  G01N2021/213 ,  G01N2201/06113 ,  G01N2201/0683

Abstract: The objective is to develop a method for determining the quality of a liquid product containing polyphenols. The present invention is a method that is a significant improvement over existing methods that use conventional laboratory instrumentation to study the quality of liquid products. The method uses an adsorption cell with a small mirror as a reflecting surface and acts as a substrate for the adsorption of the liquid's polyphenols on its surface. The polyphenol's film thickness is measured by laser ellipsometry. Light from a monochromatic light source is reflected from the thin film of polyphenol, which changes the light's optical properties and are sensed using the principles of ellipsometry. The changes in state of polarized light are translated into graphical illustrations of measured and computed parameters that can be recognized and interpreted as distinctive properties of liquid product quality.

Abstract translation: 目的是开发一种用于测定含有多酚的液体产品的质量的方法。 本发明是一种比使用常规实验室仪器研究液体产品质量的现有方法的显着改进方法。 该方法使用具有小反射镜的吸附单元作为反射面，作为表面吸附液体多酚的基板。 通过激光椭圆测量法测量多酚的膜厚度。 来自单色光源的光从多酚的薄膜反射，其改变光的光学性质并且使用椭偏仪的原理来感测。 偏振光状态的变化被转换为可以被识别和解释为液体产品质量的独特性质的测量和计算参数的图示。

公开(公告)号：US20150153287A1

公开(公告)日：2015-06-04

申请号：US14617303

申请日：2015-02-09

Applicant: DEKA Products Limited Partnership

Inventor： Jacob W. Scarpaci ,  Jason M. Sachs ,  Simon C. Helmore

IPC: G01N21/90 ,  G01N21/21

CPC classification number: G01N21/21 ,  A61M1/14 ,  G01J4/04 ,  G01N21/90 ,  G01N2201/0612 ,  G01N2201/0683

Abstract: Methods and apparatus for concentration determination using polarized light. The apparatus includes a first polarized light source having a first light source polarization axis and a second polarized light source having a second light source polarization axis generally perpendicular to the first light source polarization axis. Also, a first polarized light receiver having a first polarized light receiver polarization axis and configured to measure an intensity of light transmitted from the first light receiver polarizer and a second polarized light receiver having a second polarized light receiver polarization axis substantially perpendicular to the first light receiver polarization axis and configured to measure an intensity of light transmitted from the second light receiver polarizer, wherein the first and second light receiver polarization axes are generally +/−45 degrees relative to the first and second light source polarization axes.

Abstract translation: 使用偏振光进行浓度测定的方法和装置。 该装置包括具有第一光源偏振轴的第一偏振光源和具有大致垂直于第一光源偏振轴的第二光源偏振轴的第二偏振光源。 此外，具有第一偏振光接收偏振轴并被配置为测量从第一光接收偏振器透射的光的强度的第一偏振光接收器和具有基本上垂直于第一光的第二偏振光接收偏振轴的第二偏振光接收器 接收器偏振轴并且被配置为测量从第二光接收偏振器透射的光的强度，其中第一和第二光接收偏振轴相对于第一和第二光源偏振轴通常为+/- 45度。

公开(公告)号：US20150146200A1

公开(公告)日：2015-05-28

申请号：US14396908

申请日：2013-04-24

Applicant: Hitachi High-Technologies Corporation

Inventor： Toshifumi Honda ,  Yuta Urano ,  Takahiro Jingu ,  Akira Hamamatsu

IPC: G01N21/95 ,  G01J1/04

CPC classification number: G01N21/8806 ,  G01J1/0474 ,  G01J1/44 ,  G01N21/9501 ,  G01N21/956 ,  G01N2201/06113 ,  G01N2201/068 ,  G01N2201/0683 ,  G01N2201/0697 ,  G01N2201/10 ,  G01N2201/12

Abstract: To detect an infinitesimal defect, highly precisely measure the dimensions of the detect, a detect inspection device is configured to comprise: a irradiation unit which irradiate light in a linear region on a surface of a sample; a detection unit which detect light from the linear region; and a signal processing unit which processes a signal obtained by detecting light and detecting a defect. The detection unit includes: an optical assembly which diffuses the light from the sample in one direction and forms an image in a direction orthogonal to the one direction; and a detection assembly having an array sensor in which detection pixels are positioned two-dimensionally, which detects the light diffused in the one direction and imaged in the direction orthogonal to the one direction, adds output signals of each of the detection pixels aligned in the direction in which the light is diffused, and outputs same.

Abstract translation: 为了检测无限小的缺陷，高度精确地测量检测器的尺寸，检测检查装置被配置为包括：照射单元，其照射样品表面上的线性区域中的光; 检测单元，其检测来自所述线性区域的光; 以及信号处理单元，其处理通过检测光而获得的信号并检测缺陷。 检测单元包括：光学组件，其在一个方向上扩散来自样品的光并在与该一个方向正交的方向上形成图像; 以及检测组件，其具有阵列传感器，其中检测像素被二维地定位，其检测沿与所述一个方向正交的方向成像的沿所述一个方向漫射的光，并将每个所述检测像素的输出信号相加， 光漫射的方向，并输出。

公开(公告)号：US08743355B2

公开(公告)日：2014-06-03

申请号：US13950054

申请日：2013-07-24

Applicant: Valentin Korman

Inventor： Valentin Korman

IPC: G01N33/48

CPC classification number: A61B5/14532 ,  A61B5/1455 ,  A61B5/14558 ,  A61B5/6815 ,  A61B5/7225 ,  A61B2560/0443 ,  A61B2562/0238 ,  G01N21/21 ,  G01N2201/062 ,  G01N2201/0683

Abstract: A glucose sensor comprising an optical energy source having an emitter with an emission pattern; a first polarizer intersecting the emission pattern; a second polarizer spaced a distance from the first polarizer and intersecting the emission pattern, the second polarizer rotated relative to the first polarizer by a first rotational amount Θ; a first optical detector intersecting the emission pattern; a second optical detector positioned proximal to the second polarizer, the first polarizer and the second polarizer being positioned between the optical energy source and the second optical detector, the second optical detector intersecting the emission pattern; a compensating circuit coupled to the second optical detector; and a subtractor circuit coupled to the compensating circuit and the first optical detector.

Abstract translation: 一种葡萄糖传感器，包括具有发射器的光能源，其具有发射图案; 与发射图案相交的第一偏振片; 与第一偏振器间隔开一定距离并与发射图案相交的第二偏振器，第二偏振器相对于第一偏振器相对于第一偏转器旋转第一旋转量Θ; 与发射图案相交的第一光学检测器; 位于第二偏振器附近的第二光学检测器，第一偏振器和第二偏振器位于光能源和第二光学检测器之间，第二光学检测器与发射图案相交; 耦合到所述第二光学检测器的补偿电路; 以及耦合到所述补偿电路和所述第一光学检测器的减法器电路。