公开(公告)号：AU6467098A

公开(公告)日：1998-10-30

申请号：AU6467098

申请日：1998-03-16

Applicant: DADE MICROSCAN INC

Inventor： GODSEY JAMES H ,  NOTHAFT DANIEL M

IPC: C12Q1/04 ,  C12Q1/00

公开(公告)号：CA2257609A1

公开(公告)日：1998-10-15

申请号：CA2257609

申请日：1998-03-16

Applicant: DADE MICROSCAN INC

Inventor： GODSEY JAMES H ,  NOTHAFT DANIEL M

IPC: C12Q1/04 ,  C12Q1/34 ,  C12M1/40 ,  C12Q1/527 ,  C12Q1/58

Abstract: The present invention relates to universal test systems and methods of use thereof for identifying a microorganism among at least two groups of widely divergent microorganisms. The universal test system comprises a predetermined combination of non-redundant biochemical tests comprising a substrate for at least one enzyme wherein the substrate, if acted on by the enzyme results in formation of a detectable product. Detectable products from the combination of biochemical tests are then used to identify the microorganism.

公开(公告)号：ES2108109T3

公开(公告)日：1997-12-16

申请号：ES92907537

申请日：1992-02-10

Applicant: DADE MICROSCAN INC

Inventor： SHERMAN DAVID GORDON ,  BUSH CHARLENE ELEANOR ,  BENINSIG LAURA ANN ,  VANDENBRINK KURT MATHEW

IPC: C07H21/02 ,  A61K49/00 ,  C07H21/00 ,  C07H21/04 ,  C07H23/00 ,  C12Q1/68

Abstract: Rare earth chelate-conjugated oligonucleotides useful in nucleic acid hybridization assays and for generating chelate-labelled probes of any desired sequence are disclosed. The particular class of chelates utilized exhibit an unusually high efficiency of rare earth element capture, correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy compared to other structurally related chelate compounds.

公开(公告)号：AT156522T

公开(公告)日：1997-08-15

申请号：AT92907537

申请日：1992-02-10

Applicant: DADE MICROSCAN INC

Inventor： SHERMAN DAVID GORDON ,  BUSH CHARLENE ELEANOR ,  BENINSIG LAURA ANN ,  VANDENBRINK KURT MATHEW

IPC: C07H21/02 ,  A61K49/00 ,  C07H21/00 ,  C07H21/04 ,  C07H23/00 ,  C12Q1/68

Abstract: Rare earth chelate-conjugated oligonucleotides useful in nucleic acid hybridization assays and for generating chelate-labelled probes of any desired sequence are disclosed. The particular class of chelates utilized exhibit an unusually high efficiency of rare earth element capture, correlated with emission of a high level of signal in time-resolved fluorescence spectroscopy compared to other structurally related chelate compounds.

公开(公告)号：ES2093819T3

公开(公告)日：1997-01-01

申请号：ES92902996

申请日：1991-12-23

Applicant: DADE MICROSCAN INC

Inventor： BADAL ROBERT ,  KELLEY ROGER ,  SAND THEODORE T ,  BASCOMB SHOSHANA

IPC: C12Q1/04 ,  C12Q1/18

公开(公告)号：AU4834100A

公开(公告)日：2000-11-17

申请号：AU4834100

申请日：2000-05-01

Applicant: DADE MICROSCAN INC

Inventor： WILLIAM GREGORY B ,  NOTHAFT DANIEL ,  ENSCOE GLENN F ,  BURTNER KATHLEEN N ,  KANGAS MONTE

IPC: C12M1/20 ,  C12M1/34 ,  G01N35/02

公开(公告)号：ES2102505T3

公开(公告)日：1997-08-01

申请号：ES92911242

申请日：1992-04-29

Applicant: DADE MICROSCAN INC

Inventor： JOHNSTON JUDITH ,  FELLAND TRACY ,  BASCOMB SHOSHANA ,  GODSEY JAMES H

IPC: C12Q1/18 ,  C12Q1/02 ,  C12Q1/20 ,  C12N1/38 ,  C12Q1/34

Abstract: In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamese inducing antibiotic and a beta-lactam indicator antibiotic [which kills or inhibits the growth of bacteria] unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.

公开(公告)号：DE69219989D1

公开(公告)日：1997-07-03

申请号：DE69219989

申请日：1992-04-29

Applicant: DADE MICROSCAN INC

Inventor： JOHNSTON JUDITH ,  FELLAND TRACY ,  BASCOMB SHOSHANA ,  GODSEY JAMES

IPC: C12Q1/18 ,  C12Q1/02 ,  C12Q1/20 ,  C12N1/38 ,  C12Q1/34

Abstract: In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamese inducing antibiotic and a beta-lactam indicator antibiotic [which kills or inhibits the growth of bacteria] unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.

公开(公告)号：DE69213711T2

公开(公告)日：1997-04-17

申请号：DE69213711

申请日：1992-10-27

Applicant: DADE MICROSCAN INC

Inventor： GRINER CHRISTOPHER ,  MALONE BRIAN

IPC: B01L99/00 ,  B01L3/00 ,  B01L9/00 ,  G01N21/17 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  A47B88/00

Abstract: A holder for storing a specimen tray with a removable cover member includes a frame with oppositely facing first and second access openings The first access opening receives the specimen tray and cover member. The holder supports the specimen tray and cover member within the storage area between a pair of oppositely spaced tray support ledges. The second access opening receives an external member that moves vertically in the storage area to lift the specimen tray from the tray support ledges and that moves horizontally out of the storage area to move the lifted specimen tray from the storage area through the second access opening. The holder pivots the cover member away from the specimen tray to retain the cover member in a tilted orientation within the storage area free of the removed specimen tray until its return.

公开(公告)号：DE69217957D1

公开(公告)日：1997-04-10

申请号：DE69217957

申请日：1992-07-23

Applicant: DADE MICROSCAN INC

Inventor： VAIDYA HEMANT

IPC: G01N33/531 ,  G01N33/53 ,  G01N33/543 ,  G01N33/563 ,  G01N33/573 ,  G01N33/74 ,  G01N33/76