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公开(公告)号:AU2005231721A1
公开(公告)日:2005-10-20
申请号:AU2005231721
申请日:2005-03-28
Applicant: HYCLONE LAB INC
Inventor: ZILLES TRACY , GRAETZ GARY H
IPC: A61B19/00 , A61M1/00 , A61M1/02 , B01D61/18 , B01D61/22 , B01L3/00 , B65D33/00 , B65D33/02 , B65D33/36 , B65D81/00
Abstract: A mobile first housing bounds a substantially sterile clean room, a filtration room, and at least one change room communicating between clean room. A fluid filtration system is disposed within the first housing, the filtration system includes a first support container in which a disposable fill bag is disposed. A disposable fluid line extends between the fill bag and the at least one filter. A support bin is also disposed within the first housing. A disposable pooling bag is disposed within the support bin, the pooling bag being in fluid communication with the at least one filter. A disposable fill line has a first end in fluid communication with the pooling bag and an opposing second end disposed within the clean room.
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公开(公告)号:AT361783T
公开(公告)日:2007-06-15
申请号:AT04251715
申请日:2004-03-25
Applicant: HYCLONE LAB INC
Inventor: GOODWIN MICHAEL E , ELGAN GREGORY P , LARSEN JEREMY K
Abstract: A container system includes a substantially rigid container having a floor and a side wall upstanding therefrom. The side wall and floor bound a chamber. A magnetic mixer is disposed below the floor of the container. A mixing bag assembly is disposed within the chamber of the container. The mixing bag assembly includes a collapsible body having a first end and an opposing second end. The collapsible body bounds a compartment. A mixing dish is disposed at the second end of the collapsible body so as to communicate with the compartment thereof. A magnetic stir bar is disposed on the mixing dish.
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公开(公告)号:CA2559537A1
公开(公告)日:2005-11-10
申请号:CA2559537
申请日:2005-04-22
Applicant: BAXTER INT , HYCLONE LAB INC , BAXTER HEALTHCARE SA
Inventor: OAKLEY ROBERT V , HASAN FAUAD F , LARSEN JEREMY K , GOODWIN MICHAEL E , KUNAS KURT T , JONES NEPHI D
Abstract: The present invention relates to a stirred-tank reactor system and methods o f preparing such systems. The present invention further encompasses the use of the stirred-tank reactor system as a disposable bioreactor (104) and in kits with disposable elements.
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公开(公告)号:CA2558032A1
公开(公告)日:2005-10-20
申请号:CA2558032
申请日:2005-03-28
Applicant: HYCLONE LAB INC
Inventor: ZILLES TRACY , GRAETZ GARY H
IPC: B65D81/00 , A61B19/00 , A61M1/00 , A61M1/02 , B01D61/18 , B01D61/22 , B01L3/00 , B65D33/00 , B65D33/02 , B65D33/36
Abstract: A mobile first housing bounds a substantially sterile clean room, a filtration room, and at least one change room communicating between clean room. A fluid filtration system is disposed within the first housing, the filtration system includes a first support container in which a disposable fill bag is disposed. A disposable fluid line extends between the fill bag and the at least one filter. A support bin is also disposed within the first housing. A disposable pooling bag is disposed within the support bin, the pooling bag being in fluid communication with the at least one filter. A disposable fill line has a first end in fluid communication with the pooling bag and an opposing second end disposed within the clean room.
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公开(公告)号:AU713099B2
公开(公告)日:1999-11-25
申请号:AU3303697
申请日:1997-06-10
Applicant: MERCK & CO INC , HYCLONE LAB INC
Inventor: RIENSTRA MARK S , RADCLIFF WENDY L , EKAMBARAM ANAND , STEWART DOYLE W , ALLRED BRETT L
Abstract: The present invention relates to a package for storing, mixing, resuspending, and dispensing sterile or non-sterile solutions or suspensions. The invention comprises a collapsible, sterilizable bag (1) having fittings for tubes (13, 15) which provide for the introduction and exit of fluids and solids into and out of the bag (1). A mixing block (60) having spray arms (66) is also provided within the bag (1) for mixing and resuspending the contents within the collapsible bag (1). Dip tubes (10, 11) are provided to withdraw liquid from the bag and is recirculated through a return tube (12) which is connected to the mixing block (60). The recirculated liquid is channeled to spray arms (66) and is reintroduced into the bag (1) through ports (64, 69) thereby providing a closed loop system for mixing. Additionally, a structural support device (2) is provided for supporting the collapsible bag during shipment, filling, and dispensing. Unlike conventional stainless steeel equipment, the system is disposable, does not require cleaning, provides for safe, rapid and accurate resuspension of suspended solids, and can accommodate a wide range of liquid volumes.
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公开(公告)号:AU3303697A
公开(公告)日:1998-01-07
申请号:AU3303697
申请日:1997-06-10
Applicant: MERCK & CO INC , HYCLONE LAB INC
Inventor: RIENSTRA MARK S , RADCLIFF WENDY L , EKAMBARAM ANAND , STEWART DOYLE W , ALLRED BRETT L
Abstract: The present invention relates to a package for storing, mixing, resuspending, and dispensing sterile or non-sterile solutions or suspensions. The invention comprises a collapsible, sterilizable bag (1) having fittings for tubes (13, 15) which provide for the introduction and exit of fluids and solids into and out of the bag (1). A mixing block (60) having spray arms (66) is also provided within the bag (1) for mixing and resuspending the contents within the collapsible bag (1). Dip tubes (10, 11) are provided to withdraw liquid from the bag and is recirculated through a return tube (12) which is connected to the mixing block (60). The recirculated liquid is channeled to spray arms (66) and is reintroduced into the bag (1) through ports (64, 69) thereby providing a closed loop system for mixing. Additionally, a structural support device (2) is provided for supporting the collapsible bag during shipment, filling, and dispensing. Unlike conventional stainless steeel equipment, the system is disposable, does not require cleaning, provides for safe, rapid and accurate resuspension of suspended solids, and can accommodate a wide range of liquid volumes.
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公开(公告)号:DE3882797T2
公开(公告)日:1994-03-10
申请号:DE3882797
申请日:1988-02-19
Applicant: HYCLONE LAB INC
Inventor: OHLSON STEN
IPC: B01J20/281 , B01J20/32 , C12Q1/00 , G01N30/88 , C07K3/20 , A61K39/44 , A61K39/395 , G01N33/53 , G01N30/00 , B01D15/08
Abstract: The invention relates to a high performance affinity chromatographic system characterized by an immobilized active substance interacting weakly (Kdiss >10 M) with the desired structure of the type or types of molecule to be separated. The substance is covalently bound in its active state on a carrier of a solid, preferably porous, organic or inorganic material thereby making it suitable for use in the so-called HPLC or HPLAC technique for the separation of e.g. biomolecules. Examples of useful inorganic materials are silica or glass, or organic materials such as plastics or polysaccharides. Separation takes place by the mobile liquid being led through the column packed with the immobilized active substance of weak affinity for the complementary substances. Examples of such immobilized ligands are antibodies or fragments thereof, antigens or fragments thereof and various receptor substances.
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公开(公告)号:BR112014000768B1
公开(公告)日:2020-12-15
申请号:BR112014000768
申请日:2012-07-10
Applicant: HYCLONE LAB INC , LIFE TECHNOLOGIES CORP
Inventor: BRANDON M KNUDSEN , JEREMY K LARSEN , MICHAEL E GOODWIN , PATRICK L DRAPER
IPC: B65B3/00
Abstract: sistemas coletores de fluidos um sistema coletor de fluido inclui um coletor com ao menos seções de folhas flexíveis opostas soldadas entre si para formar um percurso de fluxo de fluido entre el as, uma 5 entrada de fluido que se comunica com o percurso de fluxo de fluido. diversos recipientes receptores estão em comunicação fluida com o percurso de fluxo de fluido do coletor, cada recipiente receptor delimitando um compartimento. os recipientes receptores podem ser formados 10 integrais com o coletor por soldagem entre si de um a segunda seção das folhas flexíveis opostas ou podem compreender recipientes separados que estão acoplados ao coletor.
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公开(公告)号:DK1756259T3
公开(公告)日:2013-10-07
申请号:DK05739820
申请日:2005-04-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , HYCLONE LAB INC
Inventor: KUNAS KURT T , OAKLEY ROBERT V , HASAN FAUAD F , GOODWIN MICHAEL E , LARSEN JEREMY K , JONES NEPHI D
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公开(公告)号:CA2559537C
公开(公告)日:2013-02-19
申请号:CA2559537
申请日:2005-04-22
Applicant: BAXTER INT , BAXTER HEALTHCARE SA , HYCLONE LAB INC
Inventor: KUNAS KURT T , OAKLEY ROBERT V , HASAN FAUAD F , GOODWIN MICHAEL E , LARSEN JEREMY K , JONES NEPHI D
Abstract: The present invention relates to a stirred-tank reactor system and methods of preparing such systems. The present invention further encompasses the use of the stirred-tank reactor system as a disposable bioreactor (104) and in kits with disposable elements.
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