Abstract:
PROBLEM TO BE SOLVED: To provide a container system with which the time, the cost, the labor necessary for cleaning and sterilizing are minimized. SOLUTION: This container system includes a substantially rigid container 12 having a floor 30 and a side wall upstanding therefrom. The side wall and floor 30 bound a chamber 34. A magnetic mixer 18 is disposed below the floor 30 of the container 12. A mixing bag assembly 16 is disposed within the chamber 34 of the container 12. The mixing bag assembly 16 includes a collapsible body having a first end and an opposing second end. The collapsible body bounds a compartment 86. A mixing dish 120 is disposed at the second end of the collapsible body so as to communicate with the compartment 86 thereof. A magnetic stir bar 140 is disposed on the mixing dish 120. COPYRIGHT: (C)2005,JPO&NCIPI
Abstract:
PROBLEM TO BE SOLVED: To provide connection systems for forming sterile fluid connections outside of a sterile environment, which is used with large diameter tubing for the large scale flow of sterile fluids. SOLUTION: The system for forming fluid connection includes a first connector (12) and a second connector (14). Both connectors have a membrane (19, 19') mounted on a distal end (27) thereof. A support member (16) or other fasteners (214, 220) facilitates the coupling of the connectors together so that the membranes are abutted together. Radiant or other form of energy is applied to the abutted membranes so as to sterilize the membranes and melt the membranes so that a flow path is formed therethrough. COPYRIGHT: (C)2011,JPO&INPIT
Abstract:
PROBLEM TO BE SOLVED: To provide a large capacity flexible container that keeps at least 200 L of a fluid, is completely supported by a support vessel, and enables the fluid to be charged or discharged without a wrinkle. SOLUTION: The container has a plurality of panels bonded to each other to form a sleeve (64). The panels (12 to 18) each have an end and cooperate to determine an imaginary surface (P) at one end of the sleeve (64). The container (10) further has end panels (20 and 22) that are connected to the panels at one end of the sleeve (64). The end panels each have a portion extending beyond at least the imaginary surface (P). A support box (100) is mounted to support the vessel. COPYRIGHT: (C)2008,JPO&INPIT
Abstract:
A fluid manifold system includes a manifold having at least portions of opposing flexible sheets welded together to form a fluid flow path therebetween, a fluid inlet communicating with the fluid flow path. A plurality of receiving containers are in fluid communication with the fluid flow path of the manifold, each receiving container bounding a compartment. The receiving containers can be formed integral with the manifold by welding together a second portion of the opposing flexible sheets or can comprise separate containers that are coupled to the manifold.
Abstract:
A system for sterilizing a fluid includes a fluid source and a sterilization container bounding a fluid flow path that is in fluid communication with the fluid source. The sterilization container is comprised of one or more polymeric walls. An electron beam generator is configured to direct an electron beam through at least a portion of the fluid flow path of the sterilization container, the electron beam being sufficient to sterilize a fluid within the fluid flow path.
Abstract:
A system for mixing a liquid solution or suspension includes a support housing bounding a compartment and a collapsible bag disposed within the compartment. A mixer is disposed within the collapsible bag while a sparger delivers a gas to the lower end of the collapsible bag. A gas outlet line extends from an upper end of the collapsible bag to a condenser assembly. A gas exhaust line and a fluid collection line both extend from the condenser assembly.
Abstract:
A system for forming a fluid connection includes a first connector (12) and a second connector (14). Both connectors include a tubular body (18,18') having a membrane (19,19') mounted on a distal end (27) thereof. A support member (16) or other fastener (214,220) facilitates the coupling of the connectors together so that the membranes are abutted together. Radiant or other form of energy is applied to the abutted membranes so as to sterilize the membranes and melt the membranes so that a passage is formed therethrough.
Abstract:
A system for forming a fluid connection includes a first connector (12) a nd a second connector (14). Both connectors include a tubular body (18,18') having a membrane (19,19') mounted on a distal end (27) thereof. A support m ember (16) or other fastener (214,220) facilitates the coupling of the conne ctors together so that the membranes are abutted together. Radiant or other form of energy is applied to the abutted membranes so as to sterilize the me mbranes and melt the membranes so that a passage is formed therethrough.
Abstract:
A sparger 140 includes a body bounding a compartment. A tubular port 162 or tube is coupled with the body. The tubular port 162 or tube bounds a passage that communicates with the compartment 160 of the body. At least a portion of the body includes of a first sparging sheet 154. The first sparing sheet includes a flexible sheet of a gas permeable material such that a gas passing into the compartment of the body through the passage can exit the compartment by permeating through the first sparging sheet.
Abstract:
The present invention relates to a stirred-tank reactor system and methods of preparing such systems. The present invention further encompasses the use of the stirred-tank reactor system as a disposable bioreactor (104) and in kits with disposable elements.