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21.发明申请公开(公告)号：US20180023104A1
公开(公告)日：2018-01-25
申请号：US15656482
申请日：2017-07-21
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Stephen Cartman , Jonathan Combe , Alexander B. Foster , Jonathan Kennedy
CPC classification number: C12P13/005 , C08G69/08 , C08G69/10 , C12N9/0006 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N15/52 , C12Y101/01021 , C12Y102/01003 , C12Y102/99006 , C12Y203/01009 , C12Y206/01
Abstract: This disclosure relates to genome-scale attenuation or knockout strategies for directing carbon flux to certain carbon based building blocks within the 7-aminoheptanoic acid (7-AHA) and 6-aminohexanoic acid (6-AHA) biosynthesis pathways, for example, to achieve reduced flux to unwanted side products while achieving increased production of desired intermediates and end products. This disclosure also relates to non-naturally occurring mutant bacterial strains comprising one or more gene disruptions in aldehyde reductase and/or aldehyde dehydrogenase genes that are generated to direct carbon flux to certain carbon based building blocks. This disclosure further relates to a method for enhancing production of carbon based building blocks by generating non-naturally occurring mutant bacterial strains, culturing said mutant bacterial strains in the presence of suitable substrates or under desired growth conditions, and substantially purifying the desired end product.
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22.发明申请公开(公告)号：US20180023103A1
公开(公告)日：2018-01-25
申请号：US15659505
申请日：2017-07-25
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett FOSTER , Stephen Thomas CARTMAN , Jonathan KENNEDY , William Joseph SIMMONS
IPC: C12P7/62 , C07C59/147 , C07C47/19 , C07C223/02 , C07C225/06 , C07C47/12 , C07C55/16 , C12P13/00 , C12P7/44 , C12P7/18 , C12N9/88 , C12N9/04 , C12N9/10 , C12N9/16 , C07C229/08
Abstract: This document describes biochemical pathways for producing a difunctional product having an odd number of carbon atoms in vitro or in a recombinant host, or salts or derivatives thereof, by forming two terminal functional groups selected from carboxyl, amine, formyl, and hydroxyl groups in an aliphatic carbon chain backbone having an odd number of carbon atoms synthesized from (i) acetyl-CoA and propanedioyl-CoA via one or more cycles of methyl ester shielded carbon chain elongation or (ii) propanedioyl-[acp] via one or more cycles of methyl ester shielded carbon chain elongation. The biochemical pathways and metabolic engineering and cultivation strategies described herein rely on enzymes or homologs accepting methyl ester shielded aliphatic carbon chain backbones and maintaining the methyl ester shield for at least one further enzymatic step following one or more cycles of methyl ester shielded carbon chain elongation.
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23.发明申请公开(公告)号：US20180023102A1
公开(公告)日：2018-01-25
申请号：US15658958
申请日：2017-07-25
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett FOSTER , Stephen Thomas CARTMAN , Jonathan KENNEDY
CPC classification number: C12P7/44 , C12N15/52 , C12P7/24 , C12P7/62 , C12P13/001 , C12P13/005 , C12Y102/01 , C12Y102/99006 , C12Y206/01 , C12Y206/01018 , C12Y301/02
Abstract: Disclosed are methods for regulating biosynthesis of at least one of pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine, 7-aminohelptanol and 1,7-heptanediol (C7 building blocks) using a pathway having a pimeloyl-ACP intermediate, the method including the step of downregulating the activity of BioF. Also disclosed are recombinant hosts by fermentation in which the above methods are performed. Further disclosed are recombinant hosts for producing pimeloyl-ACP, the recombinant host including a deletion of a bioF gene.
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公开(公告)号：US20180023097A1
公开(公告)日：2018-01-25
申请号：US15493431
申请日：2017-04-21
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Paul S. Pearlman , Changlin Chen , Adriana Leonora Botes
CPC classification number: C12P5/026 , C12N9/001 , C12N9/0071 , C12N9/88 , C12N15/52 , C12P5/02 , C12P7/16 , C12P7/18 , C12Y103/01035 , C12Y103/08 , C12Y114/11022 , C12Y401/01033 , C12Y402/01 , C12Y402/01127 , C12Y402/03027 , Y02E50/10 , Y02E50/343 , Y02P20/52
Abstract: Disclosed are methods for producing butadiene from one or more of several diverse feedstocks including bioderived feedstocks, renewable feedstocks, petrochemical feedstocks and natural gas.
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25.发明申请公开(公告)号：US20170254000A1
公开(公告)日：2017-09-07
申请号：US15596735
申请日：2017-05-16
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Thomas E. Schmitt , Deborah M. Sarzotti
CPC classification number: D02G3/443 , A41D31/08 , D10B2201/20 , D10B2331/021 , Y10T442/2631
Abstract: Disclosed are technical fibers and yarns made with partially aromatic polyamides and a fiber having vapor phase action such as an FR cellulosic fiber. Fabrics made from such fibers and yarns demonstrate superior flame retardancy over traditional flame retardant nylon 6,6 fabrics. Further, the disclosed fibers and yarns, when blended with other flame retardant fibers, do not demonstrate the dangerous “scaffolding effect” common with flame retardant nylon 6,6 blended fabrics.
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Patent Agency Ranking
公开(公告)号：US20160297726A1
公开(公告)日：2016-10-13
申请号：US15094923
申请日：2016-04-08
Applicant: INVISTA North America S.a.r.l.
Inventor： Daniel PIENAAR , Alex CONRADIE
CPC classification number: C07C1/24 , B01D3/001 , B01D3/009 , B01D3/346 , B01D3/38 , B01D15/10 , B01D15/363 , B01D15/426 , B01J20/165 , B01J23/12 , B01J2523/395 , C07C11/09 , C07C11/167 , C07C11/18 , C12P7/42 , Y02P20/127
Abstract: The present disclosure relates to processes for production of alkene products from their alkene precursors, such as 3-hydroxyacid and alcohols, via either (1) high temperature reactive distillation with steam contact at optimal pH, (2) solvent extraction and Mulzer dehydration, (3) solid phase adsorption, desorption into an organic solvent and catalytic reaction and (4) high temperature reactive distillation with steam contact at optimal pH followed by catalytic conversion.
Abstract translation: 本公开内容涉及通过（1）在最佳pH下的蒸汽接触的高温反应蒸馏，（2）溶剂萃取和Mulzer脱水（（1）），从其烯烃前体如3-羟基酸和醇生产烯烃产物的方法， 3）固相吸附，解吸到有机溶剂和催化反应中，（4）在最佳pH下进行蒸汽接触进行高温反应蒸馏，然后进行催化转化。
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公开(公告)号：US20160185315A1
公开(公告)日：2016-06-30
申请号：US14835307
申请日：2015-08-25
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Scott WESTOBY
IPC: B60R21/235 , D03D15/00 , D03D13/00 , B60R21/2338 , D03D1/02
CPC classification number: B60R21/235 , B29C47/0057 , B29C47/0066 , B60R21/2338 , B60R2021/23509 , B60R2021/23519 , D01D5/423 , D01D5/426 , D02G3/446 , D03D1/02 , D03D13/008 , D03D15/00 , D03D15/0088 , D10B2331/02 , D10B2401/041 , D10B2401/062 , D10B2401/063 , D10B2505/124 , Y10T442/2008
Abstract: Disclosed herein is the preparation of woven fabrics suitable for use in manufacturing vehicle airbags. Such fabrics are woven from a plurality of polymeric, e.g., polyamide, warp and weft tapes which have preferably been slitted, preferably in the machine direction, from a thermoplastic polymer film, and preferably from such a film which has been drawn at least in the machine direction. The resulting fabrics exhibit both the relatively low basis weight, stiffness and small packing volume typical of nylon films, and the relatively high tear strength and high damage tolerance of yarn-based woven airbag fabrics.
Abstract translation: 本文公开了适用于制造车辆安全气囊的织造织物的制备。 这种织物是由多个聚合物，例如聚酰胺，经，纬带编织而成，其优选地在机器方向上从热塑性聚合物膜切割，优选地从这样的薄膜切割，该薄膜至少在 机器方向。 所得到的织物表现出相对较低的基重，刚度和尼龙薄膜的典型的小包装体积，以及纱线编织气囊织物相对较高的撕裂强度和高的耐损伤性。
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公开(公告)号：US20160122907A1
公开(公告)日：2016-05-05
申请号：US14952192
申请日：2014-05-29
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Hong LIU , Steven Wayne SMITH , Achille Mayelle BIVIGOU KOUMBA , Geoffey Davis HIETPAS , Willem BAKKER , Andreas J. BLAB , Tianyi LIAO , Lijuan PI
Abstract: Included are segmented polyurethane elastic fibers or spandex fibers, capable of bonding to polymer fiber such as nylon or polyamide fibers, in addition to bonding to itself, for apparel textile applications. More particularly the invention relates to bicomponent spandex fibers, with a heat resistant core and a heat sensitive sheath, spun from polymer solutions. The nylon fabrics containing such spandex fibers have enhanced stretch performance and improved surface appearance after heat treatment to activate the fusing and bonding between nylon fibers and spandex fibers.
Abstract translation: 包括的是分段聚氨酯弹性纤维或氨纶纤维，除了结合自身之外，还可以粘合到诸如尼龙或聚酰胺纤维的聚合物纤维上，用于服装纺织品应用。 更具体地，本发明涉及由聚合物溶液纺丝的双组分氨纶纤维，其具有耐热芯和热敏护套。 含有这种氨纶纤维的尼龙织物在热处理后具有增强的拉伸性能和改善的表面外观，以激活尼龙纤维和氨纶纤维之间的熔合和粘合。
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公开(公告)号：US20150314279A1
公开(公告)日：2015-11-05
申请号：US14649593
申请日：2013-12-05
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Thomas E. VOS
IPC: B01J31/18 , C07C253/10 , B01J37/00 , C07C253/30
CPC classification number: C07C253/10 , B01J31/185 , B01J37/00 , B01J2231/322 , B01J2531/847 , B01J2531/90 , C07C253/30 , C07C253/34 , C07C255/04
Abstract: The invention provides methods useful in the industrial scale process for hydrocyanation of butadiene to adiponitrile for recycle of unwanted byproduct 2-methyl-3-butenenitrile (2M3BN) by conversion to process intermediate pentenenitrile. The invention provides a process for generating catalysts useful for carrying out the hydrocyanation of butadiene to adiponitrile, the process comprising contacting the 2M3BN and a solution of a nickel-ligand catalyst in cis-2-pentenenitrile (cis-2PN), trans-2-pentenenitrile (trans-2PN), or a mixture thereof. The improved methods of the invention can provide improved catalyst solubility for bidentate ligands without a requirement for a Lewis acid catalyst promoter such as zinc chloride to be present.
Abstract translation: 本发明提供了用于将丁二烯氢化成己二腈的工业规模工艺中用于通过转化为中间体戊烯腈再循环不需要的副产物2-甲基-3-丁烯腈（2M 3 BN）的方法。 本发明提供了一种用于产生用于进行丁二烯至己二腈的氢氰化的催化剂的方法，该方法包括使2M3BN与镍 - 配位体催化剂在顺式-2-戊烯腈（顺式-2PN），反式-2- 戊烯腈（反式-2PN）或其混合物。 本发明的改进方法可以提供改进的二齿配体的催化剂溶解度，而不需要存在路易斯酸催化剂促进剂如氯化锌。
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公开(公告)号：US20150148556A1
公开(公告)日：2015-05-28
申请号：US14404037
申请日：2013-05-24
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： William J. Tenn, III
IPC: C07F9/40 , C07F15/04 , C07C253/10 , B01J31/22 , C07F9/145
CPC classification number: C07F9/06 , B01J31/185 , B01J31/2221 , B01J2231/322 , B01J2231/70 , B01J2531/847 , C07C253/10 , C07C253/30 , C07F9/145 , C07F9/4006 , C07F9/65744 , C07F15/04
Abstract: The invention provides a method of forming a phosphonate diester compound from a ligand hydrolysis product (LHP) of a phosphite ligand used in a nickel-phosphite hydrocyanation catalyst, such as for conversion of 3-pentenenitrile to adiponitrile, which serves to climinate acidic LHP compound for a hydrocyanation reaction milieu where the acidic LHP can catalyze further catalyst ligand destruction. The invention further provides phosphonate disester compounds prepared by alkylation of diarylphosphite LHP in the presence of a nickel-phosphite catalyst comprising a bidentate ligand, and a continuous hydrocyanation process for production of adiponitrile wherein catalyst ligand breakdown is inhibited through inactivation of ligand hydrolysis products towards further breakdown. A method of stabilizing a hydrocyanation catalyst is provided.
Abstract translation: 本发明提供了一种由亚磷酸氢氰化催化剂中使用的亚磷酸酯配位体的配位体水解产物（LHP）形成膦酸二酯化合物的方法，例如将3-戊烯腈转化成己二腈，其用于酸化LHP化合物 对于氢化反应环境，其中酸性LHP可以催化另外的催化剂配体破坏。 本发明还提供了在含有二齿配位体的亚磷酸二氢镍催化剂的存在下烷基化亚磷酸二氢钠LHP制备的膦酸酯二酯化合物，以及用于生产己二腈的连续氢氰化方法，其中通过使配体水解产物失活而进一步抑制催化剂配体分解 分解。 提供了一种稳定氢氰化催化剂的方法。
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