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    SYSTEM FOR HIGH PRESSURE, HIGH SHEAR PROCESSING OF FLUIDS
    21.
    发明申请
    SYSTEM FOR HIGH PRESSURE, HIGH SHEAR PROCESSING OF FLUIDS 审中-公开

    公开(公告)号：US20180080444A1

    公开(公告)日：2018-03-22

    申请号：US15562146

    申请日：2016-03-28

    Applicant: PRESSURE BIOSCIENCES, INC.

    Inventor： Edmund Y. Ting

    IPC: F04B49/22 ,  F04B37/12 ,  F04B53/10 ,  F04B53/08

    CPC classification number: F04B49/225 ,  A23L3/0155 ,  F04B9/111 ,  F04B15/02 ,  F04B19/22 ,  F04B37/12 ,  F04B53/08 ,  F04B53/10

    Abstract: A method for high fluid shear processing of a fluid uses an isolator that has a first sub-chamber for containing a first fluid and a second sub-chamber for containing a second fluid defined by a separator positioned in the chamber and movable between a first end of the chamber and a second end of the chamber. The two sub-chambers are in pressure communication with each other but are not in fluid communication with each other. A first fluid is pumped at an ultrahigh pressure into the first-sub chamber, and the pressure in the first sub-chamber causes a second fluid to be processed to be discharged from the second sub-chamber into a processing valve. A system is also provided for performing the steps of this method.

    PRESSURE CYCLING SYSTEMS AND RELATED METHOD
    22.
    发明申请
    PRESSURE CYCLING SYSTEMS AND RELATED METHOD 审中-公开
    压力循环系统及相关方法

    公开(公告)号：WO2008092102A9

    公开(公告)日：2010-11-18

    申请号：PCT/US2008052089

    申请日：2008-01-25

    Applicant: PRESSURE BIOSCIENCES INC ,  TING EDMUND Y

    Inventor： TING EDMUND Y

    IPC: B01J3/00 ,  B01J3/03 ,  C12M1/00

    CPC classification number: B01J3/00 ,  B01J3/03 ,  B01J2219/00065 ,  B01J2219/00162 ,  B01J2219/002 ,  B01J2219/00213 ,  B01J2219/00231

    Abstract: A pressure cycling system includes a reaction chamber configured to receive a sample and a charge pump in fluid communication with the reaction chamber. The charge pump is operable to convey a fluid from a fluid source toward the reaction chamber. The system also includes a check valve disposed between the charge pump and the reaction chamber. The check valve is operable to inhibit the flow of fluid from the reaction chamber toward the charge pump. A pressure intensifier is in fluid communication with the reaction chamber. The pressure intensifier is pneumatically operable to adjust a pressure in the reaction chamber. A controller is configured to control operation of the charge pump and the pressure intensifier. The controller is configured to pressurize the reaction chamber to a first pressure through operation of the charge pump. The controller is also configured to fluctuate the pressure in the reaction chamber between a second pressure and a third pressure through operation of the pressure intensifier.

    Abstract translation: 压力循环系统包括配置成接收样品的反应室和与反应室流体连通的电荷泵。 电荷泵可操作以将流体从流体源传送到反应室。 该系统还包括设置在电荷泵和反应室之间的止回阀。 止回阀可操作以阻止流体从反应室朝向电荷泵的流动。 增压器与反应室流体连通。 增压器可气动地操作以调节反应室中的压力。 控制器被配置为控制电荷泵和增压器的操作。 控制器被配置为通过操作电荷泵将反应室加压至第一压力。 控制器还被配置为通过操作压力增加器来在第二压力和第三压力之间波动反应室中的压力。

    System for high pressure, high shear processing of fluids
    25.
    发明授权
    System for high pressure, high shear processing of fluids 有权

    公开(公告)号：US10823159B2

    公开(公告)日：2020-11-03

    申请号：US15562146

    申请日：2016-03-28

    Applicant: PRESSURE BIOSCIENCES, INC.

    Inventor： Edmund Y. Ting

    IPC: F04B9/117 ,  F04B15/02 ,  F04B9/113 ,  A23L3/015 ,  F15B3/00 ,  F04B37/12 ,  F04B19/22

    Abstract: A method for high fluid shear processing of a fluid uses an isolator that has a first sub-chamber for containing a first fluid and a second sub-chamber for containing a second fluid defined by a separator positioned in the chamber and movable between a first end of the chamber and a second end of the chamber. The two sub-chambers are in pressure communication with each other but are not in fluid communication with each other. A first fluid is pumped at an ultrahigh pressure into the first-sub chamber, and the pressure in the first sub-chamber causes a second fluid to be processed to be discharged from the second sub-chamber into a processing valve. A system is also provided for performing the steps of this method.

    ULTRAHIGH PRESSURE COMPACT VALVE WITH THROTTLING CAPABILITY
    26.
    发明申请
    ULTRAHIGH PRESSURE COMPACT VALVE WITH THROTTLING CAPABILITY 审中-公开

    公开(公告)号：US20190085982A1

    公开(公告)日：2019-03-21

    申请号：US15758975

    申请日：2016-09-08

    Applicant: PRESSURE BIOSCIENCES, INC.

    Inventor： Edmund Y. Ting ,  Alexander Lazarev ,  Jun Ma

    IPC: F16K1/12 ,  F16K1/14 ,  F16K1/38 ,  F16K3/24

    Abstract: A high pressure valve includes a lever and a variable force generator for facilitating control of opening and closing the valve at high pressures. The high pressure valve includes a housing having a chamber providing fluid communication between a first port and a second port, a pin movable within the chamber between an open position and a closed position. A first end of a lever is coupled to the pin and a second end of the lever is coupled to a variable force generator. The lever pivots about a pivot point. A controller coupled to the variable force generator is configured to adjust a force applied to the second end of the lever by the variable force generator to control the movement of the pin between the open position and the closed position.

    ULTRAHIGH PRESSURE COMPACT VALVE WITH THROTTLING CAPABILITY
    28.
    发明申请
    ULTRAHIGH PRESSURE COMPACT VALVE WITH THROTTLING CAPABILITY 审中-公开
    超高压紧凑型阀具有屈曲能力

    公开(公告)号：WO2017044590A1

    公开(公告)日：2017-03-16

    申请号：PCT/US2016/050717

    申请日：2016-09-08

    Applicant: PRESSURE BIOSCIENCES, INC.

    Inventor： TING, Edmund, Y. ,  LAZAREV, Alexander ,  MA, Jun

    IPC: F16K3/24 ,  F16K1/12 ,  F16K1/38 ,  F16K31/62

    CPC classification number: F16K1/12 ,  F16K1/14 ,  F16K1/38 ,  F16K3/24 ,  F16K31/62

    Abstract: A high pressure valve includes a lever and a variable force generator for facilitating control of opening and closing the valve at high pressures. The high pressure valve includes a housing having a chamber providing fluid communication between a first port and a second port, a pin movable within the chamber between an open position and a closed position. A first end of a lever is coupled to the pin and a second end of the lever is coupled to a variable force generator. The lever pivots about a pivot point. A controller coupled to the variable force generator is configured to adjust a force applied to the second end of the lever by the variable force generator to control the movement of the pin between the open position and the closed position.

    Abstract translation: 高压阀包括杠杆和可变力发生器，用于在高压下便于控制阀的打开和关闭。 高压阀包括壳体，壳体具有在第一端口和第二端口之间提供流体连通的腔室，在腔室内在打开位置和关闭位置之间可移动的销。 杠杆的第一端联接到销，并且杆的第二端联接到可变力发生器。 杠杆围绕枢轴点枢转。 耦合到可变力发生器的控制器被配置为通过可变力发生器来调节施加到杆的第二端的力，以控制销在打开位置和关闭位置之间的运动。

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