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公开(公告)号：WO2008092102A9
公开(公告)日：2010-11-18
申请号：PCT/US2008052089
申请日：2008-01-25
Applicant: PRESSURE BIOSCIENCES INC , TING EDMUND Y
Inventor： TING EDMUND Y
CPC classification number: B01J3/00 , B01J3/03 , B01J2219/00065 , B01J2219/00162 , B01J2219/002 , B01J2219/00213 , B01J2219/00231
Abstract: A pressure cycling system includes a reaction chamber configured to receive a sample and a charge pump in fluid communication with the reaction chamber. The charge pump is operable to convey a fluid from a fluid source toward the reaction chamber. The system also includes a check valve disposed between the charge pump and the reaction chamber. The check valve is operable to inhibit the flow of fluid from the reaction chamber toward the charge pump. A pressure intensifier is in fluid communication with the reaction chamber. The pressure intensifier is pneumatically operable to adjust a pressure in the reaction chamber. A controller is configured to control operation of the charge pump and the pressure intensifier. The controller is configured to pressurize the reaction chamber to a first pressure through operation of the charge pump. The controller is also configured to fluctuate the pressure in the reaction chamber between a second pressure and a third pressure through operation of the pressure intensifier.
Abstract translation: 压力循环系统包括配置成接收样品的反应室和与反应室流体连通的电荷泵。 电荷泵可操作以将流体从流体源传送到反应室。 该系统还包括设置在电荷泵和反应室之间的止回阀。 止回阀可操作以阻止流体从反应室朝向电荷泵的流动。 增压器与反应室流体连通。 增压器可气动地操作以调节反应室中的压力。 控制器被配置为控制电荷泵和增压器的操作。 控制器被配置为通过操作电荷泵将反应室加压至第一压力。 控制器还被配置为通过操作压力增加器来在第二压力和第三压力之间波动反应室中的压力。
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2.发明申请SHREDDER FOR MECHANICAL DISRUPTION BY GENTLE CONTROLLED COMPRESSIVE ROTATION 审中-公开由温德勒控制的压缩旋转引起的机械破坏的SHREDDER
公开(公告)号：WO2010033740A3
公开(公告)日：2010-05-06
申请号：PCT/US2009057370
申请日：2009-09-17
Applicant: PRESSURE BIOSCIENCES INC , TING EDMUND Y , LAZAREV ALEXANDER , GROSS VERA , DUSSAULT CHARLES , LI CHUNQIN , LAWRENCE NATHAN , SCHUMACHER RICHARD T
Inventor： TING EDMUND Y , LAZAREV ALEXANDER , GROSS VERA , DUSSAULT CHARLES , LI CHUNQIN , LAWRENCE NATHAN , SCHUMACHER RICHARD T
IPC: G01N1/28
CPC classification number: G01N1/286 , C12M35/04 , G01N2001/2866
Abstract: The systems and techniques of the present invention can also synergistically utilize mechanical disruption processes with the use of high hydrostatic pressure extraction, such as pressure cycling extraction techniques to achieve high yield of difficult to extract sample constituents without generating high shear stress or high temperatures.
Abstract translation: 本发明的系统和技术还可协同利用机械破碎过程，使用高流体静力学压力提取（例如压力循环提取技术）以实现难以提取样品成分的高产率而不产生高剪切应力或高温。
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公开(公告)号：WO2008092102A3
公开(公告)日：2008-10-16
申请号：PCT/US2008052089
申请日：2008-01-25
Applicant: PRESSURE BIOSCIENCES INC , TING EDMUND Y
Inventor： TING EDMUND Y
CPC classification number: B01J3/00 , B01J3/03 , B01J2219/00065 , B01J2219/00162 , B01J2219/002 , B01J2219/00213 , B01J2219/00231
Abstract: A pressure cycling system includes a reaction chamber configured to receive a sample and a charge pump in fluid communication with the reaction chamber. The charge pump is operable to convey a fluid from a fluid source toward the reaction chamber. The system also includes a check valve disposed between the charge pump and the reaction chamber. The check valve is operable to inhibit the flow of fluid from the reaction chamber toward the charge pump. A pressure intensifier is in fluid communication with the reaction chamber. The pressure intensifier is pneumatically operable to adjust a pressure in the reaction chamber. A controller is configured to control operation of the charge pump and the pressure intensifier. The controller is configured to pressurize the reaction chamber to a first pressure through operation of the charge pump. The controller is also configured to fluctuate the pressure in the reaction chamber between a second pressure and a third pressure through operation of the pressure intensifier.
Abstract translation: 压力循环系统包括配置成接收样品的反应室和与反应室流体连通的电荷泵。 电荷泵可操作以将流体从流体源传送到反应室。 该系统还包括设置在电荷泵和反应室之间的止回阀。 止回阀可操作以阻止流体从反应室朝向电荷泵的流动。 增压器与反应室流体连通。 增压器可气动地操作以调节反应室中的压力。 控制器被配置为控制电荷泵和增压器的操作。 控制器被配置为通过操作电荷泵将反应室加压至第一压力。 控制器还被配置为通过操作压力增加器来在第二压力和第三压力之间波动反应室中的压力。
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4.发明申请FLOW-THROUGH HIGH HYDROSTATIC PRESSURE MICROFLUIDIC SAMPLE PREPARATION DEVICE AND RELATED METHODS THEREFOR 审中-公开流动性高静电压力微流体样品制备装置及其相关方法
公开(公告)号：WO2012024523A2
公开(公告)日：2012-02-23
申请号：PCT/US2011048302
申请日：2011-08-18
Applicant: TING EDMUND Y , LAZAREV ALEXANDER
Inventor： TING EDMUND Y , LAZAREV ALEXANDER
IPC: B01L3/02
CPC classification number: G01N1/286 , G01N35/1095 , Y10T436/25
Abstract: Described herein is a sample preparation device including a sample delivery source, an inline means of transferring the sample from the sample source into a deformable channel within a pressure vessel, and out of the channel into downstream analysis components, a deformable channel disposed within the pressure vessel, the deformable channel having an inlet end and an outlet end fluidly connectable to high pressure valves and a means to measure the fluid pressure within the deformable channel, an external source of a controlled pressurized fluid fluidly connectable to the pressure vessel and a controller system that monitors and controls the sample fluid pressure by control of the external pressure vessel fluid.
Abstract translation: 本文描述的样品制备装置包括样品输送源，将样品从样品源转移到压力容器内的可变形通道中的在线装置，并且从通道进入下游分析部件，设置在压力范围内的可变形通道 容器，可变形通道具有流体连接到高压阀的入口端和出口端，以及测量可变形通道内的流体压力的装置，可流体连接到压力容器的受控加压流体的外部源和控制器系统 其通过控制外部压力容器流体监测和控制样品流体压力。
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5.发明申请TEMPERATURE CONTROL SYSTEM IN A HIGH PRESSURE PUMP FOR FAILURE DETECTION OF VALVES AND PLUNGER SEAL 审中-公开用于故障检测阀和密封件的高压泵中的温度控制系统
公开(公告)号：WO9914498A3
公开(公告)日：1999-06-03
申请号：PCT/US9819401
申请日：1998-09-16
Applicant: FLOW INT CORP , TING EDMUND Y , RAGHAVAN CHIDAMBARAM , TREMOULET OLIVER L JR
Inventor： TING EDMUND Y , RAGHAVAN CHIDAMBARAM , TREMOULET OLIVER L JR
CPC classification number: F04B51/00 , F04B49/065 , F04B2201/0801
Abstract: A method and apparatus for diagnosing components in high-pressure pumps to indicate when a component of the pump head is malfunctioning and to identify the malfunctioning component. In one embodiment, a high-pressure pump head incorporating a diagnostic system in accordance with the invention has a pressurization chamber and a pressurizing member at least partially received in the pressurization chamber. The pressurizing member moves within the pressurization chamber along an intake action to draw fluid into the pressurization chamber and along a pressurizing action to compress fluid in the pressurization chamber. An inlet fluid control assembly is coupled to the pressurization chamber to allow fluid to enter the pressurization chamber during the intake action, and a pressurized fluid control assembly is coupled between the pressurization chamber and an outlet chamber to selectively allow pressurized fluid into the outlet chamber during the pressurizing action. The pump head may also include a diagnostic system to indicate the operational status of each of the inlet fluid control assembly, the pressurized fluid control assembly and other components of the pump head upstream from the inlet fluid control assembly with respect to a fluid flow through the pump head during the pressurizing action.
Abstract translation: 一种用于诊断高压泵中的部件的方法和装置，以指示泵头的部件何时发生故障并识别故障部件。 在一个实施例中，结合根据本发明的诊断系统的高压泵头具有至少部分地容纳在加压室中的加压室和加压构件。 加压构件沿着进气动作在加压室内移动，以将流体引入加压室，并沿加压动作压缩加压室中的流体。 入口流体控制组件联接到加压室以允许流体在进气动作期间进入加压室，并且加压流体控制组件联接在加压室和出口室之间，以选择性地允许加压流体进入出口室 加压动作。 泵头还可以包括诊断系统，用于指示进口流体控制组件，加压流体控制组件和泵头的其他部件在入口流体控制组件上游相对于流过流体流体的流体流动的操作状态 泵头在加压动作期间。
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Patent Agency Ranking
公开(公告)号：WO2007038166A3
公开(公告)日：2007-10-25
申请号：PCT/US2006036740
申请日：2006-09-21
Applicant: AVURE TECHNOLOGIES INC , TREMOULET OLIVIER L JR , MONSERUD DAVID O , TING EDMUND Y
Inventor： TREMOULET OLIVIER L JR , MONSERUD DAVID O , TING EDMUND Y
CPC classification number: F17C13/02 , A23L3/0155 , A61L2/0011 , A61L2/02 , A61L2/26 , A61L2202/14 , F17C2201/0104 , F17C2205/0311 , F17C2209/224 , F17C2209/234 , F17C2250/032 , F17C2250/038 , F17C2250/0439 , F17C2250/0491 , F17C2260/024 , H01R13/5202
Abstract: A connector for a pressure vessel includes a connector assembly having a first plurality of contacts, and a receiver assembly configured to be positioned within a receiver aperture formed in a closure of the pressure vessel and having a second plurality of contacts. The receiver assembly is configured to receive the connector assembly and place each of the first plurality of contacts in electrical contact with a corresponding one of the second plurality of contacts. A seal is provided between the connector assembly and the wall of the pressure vessel, for substantially sealing the receiver aperture from pressure within the vessel. The connector assembly is configured to be coupled to a product carrier, and sensors positioned in the vessel are coupled via the connector assembly to a data acquisition unit. When the closure is lowered onto the vessel, the receiver assembly contacts the connector assembly coupled to the carrier, closing the electrical contacts connecting the sensors to the acquisition unit.
Abstract translation: 一种用于压力容器的连接器包括：连接器组件，其具有第一多个触点;以及接收器组件，其被配置为定位在形成在压力容器的闭合件中的接收器孔内并具有第二多个触点。 接收器组件被配置成接收连接器组件并且将第一多个接触件中的每个接触件与第二多个接触件中对应的一个接触件电接触。 在连接器组件和压力容器的壁之间提供密封件，用于基本上密封容器孔口免受容器内的压力。 连接器组件被构造成联接到产品载体，并且位于容器中的传感器经由连接器组件联接到数据采集单元。 当封闭件下降到容器上时，接收器组件接触连接到载体的连接器组件，闭合将传感器连接到获取单元的电触点。
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7.发明申请METHOD FOR ULTRA HIGH PRESSURE INACTIVATION OF MICROORGANISMS IN JUICE PRODUCTS 审中-公开超高压灭活微生物在榨汁产品中的方法
公开(公告)号：WO9938394A3
公开(公告)日：1999-09-16
申请号：PCT/US9902026
申请日：1999-01-29
Applicant: FLOW INT CORP , RAGHUBEER ERROL V , TING EDMUND Y
Inventor： RAGHUBEER ERROL V , TING EDMUND Y
CPC classification number: A23L2/42 , A23L3/0155
Abstract: Methods for preparing juices having an extended shelf-life without the need for pasteurization are disclosed. Such methods employ ultra high pressure (UHP) to substantially inactivate microorganisms associated with juices. The resulting juice products retain many of the preferred fresh juice characteristics such as taste, nutrition, texture and color, characteristics that may be destroyed or diminished by thermal processing or pasteurization.
Abstract translation: 公开了制备具有延长的保存期限而不需要巴氏杀菌的汁液的方法。 这种方法采用超高压（UHP）来基本上灭活与汁有关的微生物。 由此产生的果汁产品保留了许多优选的新鲜果汁特性，例如味道，营养，质地和颜色，可能因热处理或巴氏灭菌而被破坏或减少的特性。
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公开(公告)号：AU2016318955B2
公开(公告)日：2021-10-21
申请号：AU2016318955
申请日：2016-09-08
Applicant: PRESSURE BIOSCIENCES INC
Inventor： TING EDMUND Y , LAZAREV ALEXANDER , MA JUN
Abstract: A high pressure valve includes a lever and a variable force generator for facilitating control of opening and closing the valve at high pressures. The high pressure valve includes a housing having a chamber providing fluid communication between a first port and a second port, a pin movable within the chamber between an open position and a closed position. A first end of a lever is coupled to the pin and a second end of the lever is coupled to a variable force generator. The lever pivots about a pivot point. A controller coupled to the variable force generator is configured to adjust a force applied to the second end of the lever by the variable force generator to control the movement of the pin between the open position and the closed position.
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公开(公告)号：CA3152846A1
公开(公告)日：2021-04-08
申请号：CA3152846
申请日：2020-09-30
Applicant: PRESSURE BIOSCIENCES INC
Inventor： TING EDMUND Y , LAZAREV ALEXANDER
Abstract: A valve includes a valve seat body received by a sleeve with an interference fit between the valve seat body and the sleeve. An upper end of the sleeve extends beyond an upper end of the valve seat body. A valve assembly including the valve is also provided.
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公开(公告)号：CA2851252C
公开(公告)日：2021-02-23
申请号：CA2851252
申请日：2012-10-04
Applicant: PRESSURE BIOSCIENCES INC
Inventor： TING EDMUND Y , LAZAREV ALEXANDER
IPC: G01R33/30
Abstract: The present invention is related to systems and methods for chemical and biological analysis and, in particular, to systems, apparatus, and methods of sample conditioning and analysis.
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