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    Method and device for reducing axial thrust in rotary machines and a centrifugalpump using same
    22.
    发明专利
    Method and device for reducing axial thrust in rotary machines and a centrifugalpump using same 未知

    公开(公告)号：AU4357100A

    公开(公告)日：2000-11-17

    申请号：AU4357100

    申请日：2000-04-18

    Applicant: TECHNOLOGY COMMERCIALIZATION

    Inventor： GANELIN BORIS

    IPC: F01D3/00 ,  F04D29/04 ,  F04D29/22

    Abstract: A method and device for reducing or eliminating axial thrust in a rotary machine such as a centrifugal pump or compressor by altering the fluid pressure in a cavity formed between a rotor and a housing. The device contains a disk placed along the rotor for subdividing the fluid in the cavity in such a way that all annular gap leakage flow is channeled and pumped through the space between that disk and the rotor from the center of the pump towards the periphery. As a result, the pressure in the cavity is altered to reduce and control the axial thrust on the rotor which becomes independent of the wear state of the shaft seals. In another embodiment, the step of flow subdividing is achieved by providing a set of braking vanes along the periphery of the cavity for reducing the rotational speed of the fluid coming from the cavity as well as from the annular gap and a stationary disk placed along the interior wall of the housing for directing the radial flow of that fluid towards the center of the pump.

    METHODS AND DEVICES FOR REDUCING CIRCUMFERENTIAL PRESSURE IMBALANCES IN AN IMPELLER SIDE CAVITY OF ROTARY MACHINES
    27.
    发明申请
    METHODS AND DEVICES FOR REDUCING CIRCUMFERENTIAL PRESSURE IMBALANCES IN AN IMPELLER SIDE CAVITY OF ROTARY MACHINES 审中-公开

    公开(公告)号：WO2018191022A1

    公开(公告)日：2018-10-18

    申请号：PCT/US2018/025052

    申请日：2018-03-29

    Applicant: TECHNOLOGY COMMERCIALIZATION CORP.

    Inventor： KENWORTHY, Michael, W. ,  GANELIN, Boris

    IPC: F04D29/22 ,  F04D29/42 ,  F04D29/66

    Abstract: An improved rotary machine of the invention may include a rotor 30 with an impeller 20 mounted thereon. A side cavity may be formed between the impeller 20 and the housing 8. The rotary machine may be further equipped with an annular subdividing disk 1 12, 122, 132, 142 for segmenting a fluid flow in the cavity into a first fluid flow between the disc and the impeller 20, and a second fluid flow on the other side of the disk between the disc and the housing 8. The rotary machine of the invention also features a peripheral annular space formed in the periphery of the housing in the cavity at a location adjacent to a peripheral region of the annular subdividing disk 1 12, 122, 132, 142. Importantly, this peripheral annular space is void of restrictions to circumferential fluid flow therein so as to alter the second fluid flow in the cavity in order to reduce pressure variations and flow disturbances along the circumference of the rotary machine. This in turn improves rotational balance of the rotary machine.

    METHODS FOR TREATING HEMOLYTIC DISEASES AND SICKLE CELL DISEASE
    28.
    发明申请
    METHODS FOR TREATING HEMOLYTIC DISEASES AND SICKLE CELL DISEASE 审中-公开
    治疗HEMOLYTIC DISEASES和SICKLE CELL DISEASE的方法

    公开(公告)号：WO2016168444A1

    公开(公告)日：2016-10-20

    申请号：PCT/US2016/027501

    申请日：2016-04-14

    Applicant: PURDUE RESEARCH FOUNDATION OFFICE OF TECHNOLOGY COMMERCIALIZATION ,  TURRINI, Francesco ,  PANTALEO, Antonella

    Inventor： TURRINI, Francesco ,  PANTALEO, Antonella ,  LOW, Philip S.

    IPC: A61K31/505 ,  A61K31/506 ,  C07D239/48 ,  C07D401/12 ,  C07D403/12

    CPC classification number: A61K31/506 ,  A61K31/505

    Abstract: The present disclosure generally relates to methods of treating hemolytic diseases such as sickle cell anemia using kinase inhibitors, for example, compounds that inhibit the spleen tyrosine kinse (SYK). In some embodiments a method is presented to prevent thrombosis in blood vessels of patients with a hemolytic disease comprising the step of: administrating to a patient having at least one hemolytic disease a therapeutically effective amount of at least one SYK inhibitor. In some embodiments the method includes repeatedly administering the SYK kinase inhibitor to a patient.

    Abstract translation: 本公开总体上涉及使用激酶抑制剂治疗溶血性疾病如镰状细胞性贫血的方法，例如抑制脾脏酪氨酸激酶（SYK）的化合物。 在一些实施方案中，提出了一种用于预防患有溶血性疾病的患者的血管中的血栓形成的方法，包括以下步骤：向具有至少一种溶血性疾病的患者施用治疗有效量的至少一种SYK抑制剂。 在一些实施方案中，该方法包括向患者重复施用SYK激酶抑制剂。

    A COUNTERBALANCE SYSTEM AND/OR A METHOD FOR COUNTERBALANCING A LOAD
    29.
    发明申请
    A COUNTERBALANCE SYSTEM AND/OR A METHOD FOR COUNTERBALANCING A LOAD 审中-公开
    一种反平衡系统和/或一种用于计数负荷的方法

    公开(公告)号：WO2016154708A1

    公开(公告)日：2016-10-06

    申请号：PCT/CA2015/000203

    申请日：2015-03-31

    Applicant: CENTRE FOR IMAGING TECHNOLOGY COMMERCIALIZATION (CIMTEC) ,  THE UNIVERSITY OF WESTERN ONTARIO

    Inventor： BAX, Jeffrey ,  WARING, Christopher ,  FENSTER, Aaron

    IPC: B65G9/00 ,  A61B19/00 ,  F16M11/12 ,  F16M13/00

    CPC classification number: F16M13/005 ,  A61B8/4218 ,  A61B8/44 ,  B65G9/00 ,  F16M11/046 ,  F16M11/048 ,  F16M11/12 ,  F16M2200/041 ,  F16M2200/063

    Abstract: Disclosed is a counterbalance system for moving a payload and a method for counterbalancing the payload. The system and method comprise a resilient member that is in communication with the payload to be moved and two resilient members that are in communication with either end of the first resilient member. An actuator is in communication with the first and third resilient members and a payload arm, attached to the payload, is in communication with the first and second resilient members. The resilient members may be compressed and relaxed during movement of the actuator and the payload arm so that energy may be transferred between the system and the payload to counterbalance the weight of the payload.

    Abstract translation: 公开了一种用于移动有效载荷的平衡系统和用于平衡有效载荷的方法。 该系统和方法包括与要移动的有效载荷连通的弹性构件和与第一弹性构件的任一端连通的两个弹性构件。 致动器与第一和第三弹性构件连通，并且附接到有效载荷的有效载荷臂与第一和第二弹性构件连通。 在致动器和有效载荷臂的移动期间，弹性构件可以被压缩和松弛，使得能量在系统和有效载荷之间传递以平衡有效载荷的重量。

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