公开(公告)号：AU2005279799A1

公开(公告)日：2006-03-09

申请号：AU2005279799

申请日：2005-08-29

Applicant: UNIV EMORY ,  THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND

Inventor： MOSS BERNARD ,  ROBINSON HARRIET L ,  WYATT LINDA

IPC: C07K14/16 ,  A61K39/21 ,  C12N15/863

公开(公告)号：AU2003252207C1

公开(公告)日：2006-02-09

申请号：AU2003252207

申请日：2003-10-02

Applicant: THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES

Inventor： BOYD MICHAEL R

IPC: A61K38/16 ,  A61F6/00 ,  A61K47/48 ,  A61L2/00 ,  A61L2/23 ,  A61M31/00 ,  A61P31/18

公开(公告)号：AP1459A

公开(公告)日：2005-08-22

申请号：AP2002002472

申请日：2000-10-06

Applicant: TIBOTEC PHARM LTD ,  JANSSEN SCIENCES IRELAND UC ,  THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SEC DEP OF HEALTH AND HUMAN SERVIC ,  JANSSEN R&D IRELAND

Inventor： WIGERINCK PIET TOM BERT PAUL ,  WANG GUANGYANG ,  EISSENSTAT MICHAEL ,  ERICKSON JOHN W

IPC: A61K31/34 ,  A61K31/36 ,  A61P31/12 ,  A61P31/14 ,  A61P31/18 ,  A61P43/00 ,  C07D493/04

Abstract: The present invention relates to novel bis-tetrahydrofuran benzodioxolyl sulfonamide compounds which are surprisingly effective protease inhibitors. The invention also relates to pharmaceutical compositions, methods of inhibiting retrovirus proteases, in particular multidrug resistant retrovirus proteases, methods of treating or combating infection or disease associated with retrovirus infection in a mammal, and methods of inhibiting viral replication.

公开(公告)号：AU2013192A

公开(公告)日：1993-01-08

申请号：AU2013192

申请日：1992-06-05

Applicant: THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEP

Inventor： JAMES G BURKHART ,  HEINRICH V MALLING

IPC: C12N15/10 ,  C12N15/64 ,  C12N15/70 ,  C12N15/85

公开(公告)号：DE2714845C2

公开(公告)日：1985-12-05

申请号：DE2714845

申请日：1977-04-02

Applicant: THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY OF THE NAVY, ARLINGTON, VA., US

Inventor： BENO, LAWRENCE A., CAMARILLO, CALIF., US

IPC: H01P1/165 ,  H01P1/15 ,  H01P1/17 ,  H01P1/185 ,  H01Q21/24 ,  H01P1/00 ,  H01P1/10

公开(公告)号：AT3118T

公开(公告)日：1983-05-15

申请号：AT79104480

申请日：1979-11-13

Applicant: THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY U.S. DEPARTMENT OF COMMERCE

Inventor： GALLO, BENEDICT JAMES

IPC: C12N1/14 ,  C12N1/20 ,  C12N9/42

Abstract: A process and a microorganism for synthesizing cellulase enzymes are described. The microorganism is a mutant strain of an Ascomycete fungus capable of synthesizing cellulases. The synthesis of cellulases by the mutant is nonrepressed by glycerol, repressed by glucose but not subject to postrepression lag, and inducible to high levels by lactose. Furthermore, the combination of lactose with xylose elicits maximum cellulase synthesis by the mutant.

公开(公告)号：AT2398T

公开(公告)日：1983-03-15

申请号：AT79900517

申请日：1979-05-11

Applicant: THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY U.S. DEPARTMENT OF COMMERCE

Inventor： MILLER, HAROLD JOHN

IPC: B02C1/04 ,  B02C21/02 ,  E21C27/30 ,  E21F17/00

公开(公告)号：WO1994002865A1

公开(公告)日：1994-02-03

申请号：PCT/US1993006868

申请日：1993-07-21

Applicant: THE UNITED STATES OF AMERICA, represented by THE ... ,  THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ... ,  THE UNITED STATES OF AMERICA, represented by THE ...

Inventor： THE UNITED STATES OF AMERICA, represented by THE ... ,  THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ... ,  THE UNITED STATES OF AMERICA, represented by THE ... ,  WINK, David, A., Jr. ,  CLARKSON, Robert, B. ,  DESROSIERS, Marc, F.

IPC: G01R33/60

CPC classification number: A61K49/0002 ,  A61K49/20 ,  G01R33/281 ,  G01R33/60

Abstract: A method of detecting nitric oxide in a sample utilizing electron paragmagnetic resonance spectroscopy and a spin-labeled material such as fusinite to detect changes in the linewidth of the electron paramagnetic resonance signal of the spin-labeled material in the presence of nitric oxide which can be correlated to the quantity of nitric oxide in the sample.

Abstract translation: 使用电子顺磁共振光谱法和自旋标记材料如fusinite检测样品中的一氧化氮的方法，以检测在一氧化氮存在下自旋标记的材料的电子顺磁共振信号的线宽的变化，其可以是 与样品中一氧化氮的量相关。

公开(公告)号：SI3244920T1

公开(公告)日：2023-09-29

申请号：SI201631724

申请日：2016-01-15

Applicant: THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY OF AGRICULTURE UNITED STATES DEPT OF AGRIC ,  ZOETIS SERVICES LLC

Inventor： DOMINOWSKI PAUL JOSEPH ,  HARDHAM JOHN MORGAN ,  JACKSON JAMES ALAN ,  GAY CYRIL GERARD ,  RODRIGUEZ LUIS LEANDRO ,  KRUG PETER WILLIAM ,  RIEDER AIDA ELIZABETH

IPC: A61K39/00

公开(公告)号：ES2623812T3

公开(公告)日：2017-07-12

申请号：ES04811370

申请日：2004-11-12

Applicant: THE GOVERNMENT OF THE UNITED STATES OF AMERICA REPRESENTED BY THE SECRETARY DEPT OF HEALTH AND HUMAN

Inventor： PANICALI DENNIS ,  MAZZARA GAIL ,  GRITZ LINDA ,  SCHLOM JEFFREY ,  HODGE JAMES ,  TSANG KWONG-YOK

IPC: C07H21/02 ,  A61K20060101 ,  A61K39/00 ,  A61K48/00 ,  C12N7/00 ,  C12N15/00 ,  C12N15/86 ,  C12N15/863

Abstract: Un primer vector de poxvirus que contiene uno o más segmentos de ADN que codifican (i) antígeno carcinoembrionario (CEA), una porción antigénica del mismo, o una versión modificada del mismo que comprende SEQ ID NO: 4, y (ii) mucina (MUC), una porción antigénica de la misma, o una versión modificada de la misma que comprende SEQ ID NO: 2, para su uso en inducir una respuesta inmunológica contra una célula pancreática maligna en un individuo, en el que en un segundo vector de poxvirus que contiene uno o más segmentos de ADN que codifican (i) CEA, una porción antigénica del mismo, o una versión modificada del mismo que comprende SEQ ID NO: 4, y (ii) MUC, una porción antigénica de la misma, o una versión modificada de la misma que comprende SEQ ID NO: 2, se administra al individuo a intervalos regulares después de la administración del primer vector.