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公开(公告)号：KR1020130062310A
公开(公告)日：2013-06-12
申请号：KR1020130057714
申请日：2013-05-22
Applicant: (주)아모레퍼시픽
CPC classification number: C12Q1/6813 , C12Q2600/148 , C12Q2600/158 , G01N33/15
Abstract: PURPOSE: A method for screening an inhibitor of woman skin aging is provided to quickly diagnose the degree of skin aging using genes, and to evaluate skin aging. CONSTITUTION: A method for screening an inhibitor of woman skin aging caused by deficiency of female hormone comprises: a step of treating cells with a test compound; and a step of checking whether the expression of XBP1 gene is promoted in a cell after treatment. The method further comprises a step of checking whether the expression of a gene is promoted in the cells after treatment. The gene is selected from a group consisting of SREBF1(SREBP1), LMO2, TFAP2A, MEF2A, LEF1, RUNX2(OSF2), PATZ1(MAZR), ZNFN1A1, THRA, NKX2-5, SOX5, MYOG, MEIS1, IRF1, GATA3, AP1(FOS/JUN), TBP, SP1, HNF4A, KLF12(AP2REP), NKX2-1(TTF1), MYOD1, RUNX1(AML1), ZEB1 (AREB6), and TFAP2C. [Reference numerals] (AA,BB,CC,DD,EE,FF) Control group
Abstract translation: 目的：提供一种筛选女性皮肤老化抑制剂的方法，以快速诊断使用基因的皮肤老化程度，并评估皮肤老化。 构成：用于筛选由雌激素缺乏引起的女性皮肤老化抑制剂的方法包括：用试验化合物处理细胞的步骤; 以及在处理后的细胞中检查XBP1基因的表达是否被促进的步骤。 该方法还包括检查处理后的细胞中是否促进基因的表达的步骤。 该基因选自SREBF1（SREBP1），LMO2，TFAP2A，MEF2A，LEF1，RUNX2（OSF2），PATZ1（MAZR），ZNFN1A1，THRA，NKX2-5，SOX5，MYOG，MEIS1，IRF1，GATA3， AP1（FOS / JUN），TBP，SP1，HNF4A，KLF12（AP2REP），NKX2-1（TTF1），MYOD1，RUNX1（AML1），ZEB1（AREB6）和TFAP2C。 （标号）（AA，BB，CC，DD，EE，FF）对照组
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公开(公告)号：KR1020120107449A
公开(公告)日：2012-10-02
申请号：KR1020120104203
申请日：2012-09-19
Applicant: (주)아모레퍼시픽
CPC classification number: C12Q1/6883 , C12Q1/6834 , C12Q1/6844 , C12Q2600/148 , G01N33/15 , G01N33/5302 , G01N33/5308 , G01N33/6881
Abstract: PURPOSE: A kit and a method for diagnosing skin aging are provided to sensitively and quickly diagnose a degree of skin aging using a diagnosis marker. CONSTITUTION: A kit for diagnosing skin aging contains: a RAI16(AK001987)polynucleotide, a polynucleotide containing 10 or more serial nucleotides as a fragment thereof, or a complementary polynucleotide thereof; and a solid support. The kit contains a polynucleotide of NOX4(NM_016931), ALK(AB032363), ANKS1(D86982), ANP32E(AK025624), PSCD4(NM_013385), MGAT5(NM_002410), CLDND1(AF161522), LRRK1(AF086335), COL11A2(J04974), ABCF3(NM_018358), MGAT5(NM_002410), CLDND1(AF161522), LRRK1(AF086335), COL11A2(J04974), ABCF3(NM_018358), SV2B(AL110286), ZC3H11A(AF086224), CSDC2(AB027011), PPP1R12B(AB007972) or CEBPZ(AK001814), a polynucleotide containing 10 or more serial nucleotides, or a complementary polynucleotide thereof; and a solid support.
Abstract translation: 目的：提供一种用于诊断皮肤老化的试剂盒和方法，以使用诊断标记敏感且快速地诊断一定程度的皮肤老化。 构成：用于诊断皮肤老化的试剂盒包含：RAI16（AK001987）多核苷酸，含有10个或更多个连续核苷酸作为其片段的多核苷酸或其互补多核苷酸; 和坚实的支持。 该试剂盒含有NOX4（NM_016931），ALK（AB032363），ANKS1（D86982），ANP32E（AK025624），PSCD4（NM_013385），MGAT5（NM_002410），CLDND1（AF161522），LRRK1（AF086335），COL11A2（J04974） ，ABCF3（NM_018358），MGAT5（NM_002410），CLDND1（AF161522），LRRK1（AF086335），COL11A2（J04974），ABCF3（NM_018358），SV2B（AL110286），ZC3H11A（AF086224），CSDC2（AB027011），PPP1R12B（AB007972） 或CEBPZ（AK001814），含有10个或更多个序列核苷酸的多核苷酸或其互补多核苷酸; 和坚实的支持。
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公开(公告)号：KR1020120107447A
公开(公告)日：2012-10-02
申请号：KR1020120104172
申请日：2012-09-19
Applicant: (주)아모레퍼시픽
CPC classification number: C12Q1/6883 , C12Q1/6834 , C12Q1/6844 , C12Q2600/148 , G01N33/15 , G01N33/5302 , G01N33/5308 , G01N33/6881
Abstract: PURPOSE: A kit and a method for diagnosing skin aging using genes are provided to sensitively and quickly diagnose skin aging degree. CONSTITUTION: A kit for diagnosing skin aging contains: a polynucleotide of TRIB3(AK026945), a polynucleotide containing 10 or more serial nucleotides, or complementary polynucleotide thereof; and a solid support. A method for providing information for diagnosing skin aging degree comprises: a step of measuring the expression level of TRIB3(AK026945) in a subject epidermis and a step of comparing the expression level with age-specific expression level.
Abstract translation: 目的：提供使用基因诊断皮肤老化的试剂盒和方法，以敏感和快速诊断皮肤老化程度。 构成：用于诊断皮肤老化的试剂盒包含：TRIB3（AK026945）的多核苷酸，含有10个或更多个序列核苷酸的多核苷酸或其互补多核苷酸; 和坚实的支持。 提供用于诊断皮肤老化度的信息的方法包括：测量受试者表皮中TRIB3（AK026945）的表达水平的步骤和将表达水平与年龄特异性表达水平进行比较的步骤。
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公开(公告)号：KR1020110057819A
公开(公告)日：2011-06-01
申请号：KR1020090114383
申请日：2009-11-25
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A lipid composition containing ceramide, stearic acid, oil tackifier, and selectively cholesterol is provided to ensure lip moisturizing and to recover lip skin barrier function. CONSTITUTION: A lipid composition for lip contains 10-80 weight% of ceramide, 10-80 weight% of stearic acid, and 3-80 weight% of oil tackifier as an active ingredient. The ceramide is a ceramide analogue. The lipid composition further contains cholesterol as an active ingredient. The weight ratio of ceramide, stearic acid, cholesterol, and oil tackifer is 1-4 : 1-4 : 1-2 : 1-4. A cosmetic composition contains 0.01-40 weight% of lipid composition.
Abstract translation: 目的：提供含有神经酰胺，硬脂酸，油增粘剂和选择性胆固醇的脂质组合物，以确保唇部保湿并恢复唇部皮肤屏障功能。 构成：用于唇部的脂质组合物含有10-80重量％的神经酰胺，10-80重量％的硬脂酸和3-80重量％的油增粘剂作为活性成分。 神经酰胺是神经酰胺类似物。 脂质组合物还含有胆固醇作为活性成分。 神经酰胺，硬脂酸，胆固醇和油性粘合剂的重量比为1-4：1-4：1-2：1-4。 化妆品组合物含有0.01-40重量％的脂质组合物。
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公开(公告)号：KR1020100010433A
公开(公告)日：2010-02-01
申请号：KR1020080096663
申请日：2008-10-01
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K36/48 , A61K2236/331 , A61Q5/02 , A61Q5/12 , Y10S514/881
Abstract: PURPOSE: A hair cosmetic composition containing black soybean-brewed water is provided to enhance anti-oxidation, hair glossiness, and scalp effect. CONSTITUTION: A hair cosmetic composition contains 0.01-10.0 weight% of black soybean-brewed water. The water is isolated through low temperature elution. The black soybean is steamed and dried. The composition further contains 0.01~10.0 weight% of black sesame extract and cacao seed extract. The composition contains dihydroxy acetic acid as an antiseptic. The composition is used in the form of hair tonic, hair nutrition lotion, hair essence, hair serum scalp treatment, hair treatment, hair conditioner, hair shampoo or hair lotion.
Abstract translation: 目的：提供含有黑大豆酿造水的头发化妆品，以增强抗氧化，头发光泽和头皮效果。 构成：头发化妆品组合物含有0.01-10.0重量％的黑豆酿造水。 水通过低温洗脱分离。 将黑豆蒸并干燥。 该组合物还含有0.01〜10.0重量％的黑芝麻提取物和可可籽提取物。 该组合物含有二羟基乙酸作为防腐剂。 该组合物以头发补品，头发营养洗剂，头发精华，头发血清头皮治疗，头发处理，护发素，洗发剂或洗发剂的形式使用。
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Patent Agency Ranking
公开(公告)号：KR1020090130801A
公开(公告)日：2009-12-24
申请号：KR1020080124479
申请日：2008-12-09
Applicant: (주)아모레퍼시픽
Abstract: PURPOSE: A skin external composition containing ginseng seed oil or ginseng seed skin extract is provided to ensure skin improvement effect without side effects. CONSTITUTION: A skin external composition contains ginseng seed extract as an active ingredient. The ginseng seed extract is 0.001-100 weight% of ginseng seed oil or 0.001-10 weight% of ginseng seed skin extract. A method for extracting ginseng seed skin comprises: a step of pulverizing dried ginseng seed and placing the ginseng seed at room temperature in hexane organic solvent to remove oil from the ginseng seed; a step of placing the remaining ginseng seed skin in organic solvent containing water or organic solvent at room temperature; and a step of filtering extract and concentrating.
Abstract translation: 目的：提供含有人参种子油或人参种子皮肤提取物的皮肤外用组合物，以确保皮肤改善效果而没有副作用。 构成：皮肤外用组合物含有人参种子提取物作为活性成分。 人参种子提取物为人参种子油的0.001-100重量％或人参种子皮肤提取物的0.001-10重量％。 一种提取人参种子皮的方法包括：将干燥人参种子粉碎并将人参种子在室温下放置在己烷有机溶剂中以从人参种子中除去油的步骤; 在室温下将剩余的人参种子皮肤置于含水或有机溶剂的有机溶剂中的步骤; 以及过滤提取和浓缩的步骤。
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公开(公告)号：KR100879423B1
公开(公告)日：2009-01-19
申请号：KR1020077011568
申请日：2005-11-30
Applicant: (주)아모레퍼시픽
IPC: C07C251/44 , C07C251/32
CPC classification number: C07C317/32 , C07C251/44 , C07C255/61 , C07C259/18 , C07C323/47 , C07C2601/08 , C07C2601/10 , C07C2601/14 , C07D209/08 , C07D213/53 , C07D307/91 , C07D317/58 , C07D333/22 , C07D333/58 , C07D339/08
Abstract: 화학식 1로 나타내어지는 2-사이클로펜텐-1-온 옥심 유도체, 또는 그의 약학적으로 허용가능한 염은 TNF-α 또는 PDE4의 생산을 저해함으로써 TNF-α 또는 PDE4를 통해 매개된 염증성 또는 면역성 질환들에 대한 치료효과를 나타낸다.
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公开(公告)号：KR1020170002988A
公开(公告)日：2017-01-09
申请号：KR1020150093019
申请日：2015-06-30
Applicant: (주)아모레퍼시픽
Abstract: 본명세서는스펀지형태의다공성도포부, 저장부및 저점도화장료조성물을포함하는메이크업화장품에관한것으로, 구체적으로도포부의모양이변하지않는메이크업화장품을제공하며, 기존의제품보다 non-transfer효과가빨리일어나, 롱래스팅의효과가우수하고, 피부또는입술에적용시 기존제품에비해균일하게발려지는특성이있으며, 10초내외로롱래스팅효과가시작되고, 피부또는입술에적용시 컬러지속력이우수하다.
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公开(公告)号：KR101550917B1
公开(公告)日：2015-09-08
申请号：KR1020080124479
申请日：2008-12-09
Applicant: (주)아모레퍼시픽
Abstract: 본발명은인삼씨오일및 인삼씨박추출물로부터선택되는인삼씨추출물의용도에관한것으로서, 상기용도는피부보호용도, 항노화, 항주름, 피부탄력개선, 미백, 피부보습, 아토피등의피부건조질환의예방및 개선, 피지조절, 항염증, 여드름등의피부트러블예방또는개선, 피부혈색개선, 각질제거, 탈모예방, 항비듬, 모발의광택및 부드러움개선, 얼굴또는바디의볼륨및 탄력증진, 얼굴또는바디의라인개선을포함한다.
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