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公开(公告)号：KR101345442B1
公开(公告)日：2013-12-27
申请号：KR1020110045828
申请日：2011-05-16
Applicant: 서울대학교산학협력단
CPC classification number: Y02A50/473 , Y02A50/481
Abstract: 본발명은약물층과고분자층이번갈아적층되어있는층 구조를포함하는내부코어(core); 및내부코어를둘러싸고있으며, 개구부를포함하는고분자외층을포함하고, 상기에서외층의고분자및 코어내 고분자층의고분자순으로생분해성이낮은고분자인약물전달시스템을개시한다.
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公开(公告)号：KR1020130084200A
公开(公告)日：2013-07-24
申请号：KR1020120033523
申请日：2012-03-30
Applicant: 서울대학교산학협력단
CPC classification number: Y02A50/475 , Y02A50/481 , A61K47/30 , A61K35/74
Abstract: PURPOSE: A drug delivery system is provided to selectively and easily allow bacteria to adhere onto a specific layer by comprising a hydrophilic biodegradable polymer layer and a hydrophobic biodegradable polymer layer. CONSTITUTION: A drug delivery system comprises a hydrophilic biodegradable polymer layer (100) and a hydrophobic biodegradable polymer layer (111). Bacteria adhere onto the surface of one layer among the biodegradable polymer layers. A drug is contained in the biodegradable polymer layer in which bacteria did not adhere. The hydrophilic biodegradable polymer contains one or more ingredients selected from alginate or a derivative thereof, chitosan or a derivative thereof, hyaluronic acid or a derivative thereof, gelatin, collagen, polyethylene glycol (PEG), and polyvinylpyrrolidone (PVP). The hydrophobic biodegradable polymer contains one or more ingredients selected from poly-caprolactone, L-poly-lactides (LPLA), poly-glycolic acid (PGA), poly-D-lactide (PDLA), poly-lactic acid (PLA), and poly-lactic-co-glycolic acid (PLGA). [Reference numerals] (100) Hydrophobic polymer layer; (110) Amphiphilic adhesive material; (111) Hydrophilic polymer layer containing a drug
Abstract translation: 目的：提供药物递送系统以选择性且容易地通过包括亲水性可生物降解的聚合物层和疏水的可生物降解的聚合物层使细菌粘附在特定的层上。 构成：药物递送系统包括亲水性可生物降解聚合物层（100）和疏水性可生物降解聚合物层（111）。 细菌粘附在可生物降解的聚合物层中的一层的表面上。 药物包含在细菌不粘附的生物可降解聚合物层中。 亲水性生物可降解聚合物含有选自藻酸盐或其衍生物，壳聚糖或其衍生物，透明质酸或其衍生物，明胶，胶原，聚乙二醇（PEG）和聚乙烯吡咯烷酮（PVP））中的一种或多种成分。 疏水性生物降解性聚合物含有选自聚己内酯，L-聚丙交酯（LPLA），聚乙醇酸（PGA），聚-D-丙交酯（PDLA），聚乳酸（PLA）和 聚乳酸 - 共 - 乙醇酸（PLGA）。 （附图标记）（100）疏水性聚合物层; （110）两亲性粘合剂材料; （111）含有药物的亲水性聚合物层
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公开(公告)号：KR101275215B1
公开(公告)日：2013-06-17
申请号：KR1020110040713
申请日：2011-04-29
Applicant: 서울대학교산학협력단
Abstract: 본 발명은 신호 처리된 영상 정보를 받아 전기 신호로 변환해주는 주회로부, 주회로부의 정보를 받아 망막 전극을 직접 전기 신호로 자극하는 보조회로부로 구성된 고해상도 인공 망막 자극기에 관한 것이다. 이에 의해, 기존 고해상도 인공 망막 자극기가 가지고 있던 문제점들을 해결하여 고해상도 인공 망막 자극기의 효율적인 적용으로 인체 내 망막 삽입이 보다 용이하게 함으로써 시각 장애인들의 시각 확보의 질을 높이고 생활의 편의를 높이는데 기여할 수 있다.
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公开(公告)号：KR1020120122513A
公开(公告)日：2012-11-07
申请号：KR1020110040713
申请日：2011-04-29
Applicant: 서울대학교산학협력단
CPC classification number: A61F9/0017 , A61F2/14 , A61N1/0408 , A61N1/0543
Abstract: PURPOSE: An artificial high resolution retina stimulator is provided to prevent damage to cells due to heat generation. CONSTITUTION: An artificial high resolution retina stimulator comprises a main circuit unit which receives signal-processed video information and converts the information into an electric signal, and a supplementary circuit unit which receives the information of the main circuit and stimulates a retina electrode with direct electric signal. One or more supplementary circuit unit shares the main circuit unit. In the supplementary circuit unit, a decoder and a microelectrode array are integrally formed. [Reference numerals] (AA) Signal-processed video information; (BB) N number of stimulators; (CC) Circuits for driving stimulator circuit; (DD) Main circuit unit; (EE) Artificial retina stimulating chip; (FF) Date(from main circuit unit); (GG) SEL(from decoder); (HH) Memory element; (II) Programmable electric signal generator; (JJ,N1,N2,N3,N4,N5,N6,N7,N8,N9) Electrode; (KK) N_xN number of microelectrode array; (LL) Decoder; (M1,M2,M3,M4,M5,M6,M7,M8,M9) Supplementary circuit unit; (OO) Retina electrode array+supplementary circuit unit+decoder; (PP) Need of at least(N+log_2N+2 Power Line) wires
Abstract translation: 目的：提供人造高分辨率视网膜刺激器，以防止由于发热造成细胞损伤。 构成：人造高分辨率视网膜刺激器包括接收信号处理视频信息并将信息转换成电信号的主电路单元，以及接收主电路信息并用直接电刺激视网膜电极的辅助电路单元 信号。 一个或多个辅助电路单元共享主电路单元。 在辅助电路单元中，整体地形成解码器和微电极阵列。 （附图标记）（AA）信号处理的视频信息; （BB）N个刺激物; （CC）驱动电路的电路; （DD）主电路单元; （EE）人造视网膜刺激芯片; （FF）日期（从主电路单元）; （GG）SEL（来自解码器）; （HH）存储元件; （二）可编程电信号发生器; （JJ，N1，N2，N3，N4，N5，N6，N7，N8，N9）电极; （KK）N_xN微电极阵列数; （LL）解码器; （M1，M2，M3，M4，M5，M6，M7，M8，M9）补充电路单元; （OO）视网膜电极阵列+辅助电路单元+解码器; （PP）需要至少（N + log_2N + 2电源线）电线
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