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公开(公告)号：KR100918807B1
公开(公告)日：2009-09-25
申请号：KR1020080049702
申请日：2008-05-28
Applicant: 재단법인서울대학교산학협력재단
Abstract: PURPOSE: An antibacterial polymer composition is provided to ensure strong sterilizing power or antibacterial activity by reducing copper contained in a polymer. CONSTITUTION: An antibacterial polymer composition includes a copper-containing polymer and organic solvent. The antibacterial polymer composition has antibacterial activity for microorganism through reduction processing. The copper-containing polymer has a repeating unit represented by formula 1. A method for forming an antibacterial polymer film comprises the steps of: forming a copper-containing polymer film on a substance by applying the polymer composition; and imparting an antibacterial property for microorganism to the copper-containing polymer film by reducing the copper-containing polymer film using a reducing agent through chemical reduction, thermal reduction, and photo reduction.
Abstract translation: 目的：提供抗菌聚合物组合物，以通过减少聚合物中所含的铜来确保强的灭菌力或抗菌活性。 构成：抗菌聚合物组合物包括含铜聚合物和有机溶剂。 抗菌聚合物组合物通过还原处理对微生物具有抗菌活性。 含铜聚合物具有由式1表示的重复单元。抗菌聚合物膜的形成方法包括以下步骤：通过施加聚合物组合物在物质上形成含铜聚合物膜; 并通过化学还原，热还原和光还原使用还原剂还原含铜聚合物膜，将微生物的抗菌性赋予含铜聚合物膜。
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公开(公告)号：KR100912382B1
公开(公告)日：2009-08-19
申请号：KR1020070093090
申请日：2007-09-13
Applicant: 재단법인서울대학교산학협력재단
Abstract: 저항성이 높은 병원성 미생물을 단시간에 효과적으로 제거할 수 있는 실내 소독 방법 및 실내 소독 설비가 개시된다. 실내 소독 방법에서는, 미생물로 오염된 실내 공간에 과산화수소를 제공하여 미생물을 전처리한 다음, 실내 공간에 수분을 함유하는 오존 가스를 제공하여 미생물을 제거하게 된다. 이로써 유해 물질의 발생 없이 향상된 소독력으로 실내 공간의 미생물을 제거할 수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020090078195A
公开(公告)日：2009-07-17
申请号：KR1020080004020
申请日：2008-01-14
Applicant: 재단법인서울대학교산학협력재단
CPC classification number: A23C3/005 , A23C2210/15
Abstract: A method for sterilizing the raw milk is provided to allow the raw milk to be sterilized at a lower temperature within a short time with the improved sterilization effect. A method for sterilizing the raw milk comprises the step of contacting the supercritical fluid with the raw milk to inactivating the microorganism contained in the raw milk; and optionally stirring the supercritical fluid with the raw milk. Preferably the supercritical fluid comprises a mixture fluid comprising supercritical carbon dioxide, supercritical nitrous oxide or their mixture.
Abstract translation: 提供了一种用于对生奶进行灭菌的方法，以使生奶在短时间内以较低的温度灭菌，同时具有改善的杀菌效果。 对生奶进行灭菌的方法包括使超临界流体与原料乳接触以使生奶中含有的微生物失活的步骤; 并且任选地用生牛奶搅拌超临界流体。 优选地，超临界流体包括包含超临界二氧化碳，超临界一氧化二氮或它们的混合物的混合流体。
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公开(公告)号：KR1020090027913A
公开(公告)日：2009-03-18
申请号：KR1020070093102
申请日：2007-09-13
Applicant: 재단법인서울대학교산학협력재단
CPC classification number: A61L2/07 , A61L2/22 , A61L2202/12
Abstract: A method for inactivating biofilm is provided, which inactivates the biofilm in an improved disinfecting power using the supercritical fluid in a short time. A method for inactivating biofilm using the supercritical fluid comprises: a step for positioning an object in which the biofilm is formed in the surface at the high pressure container; and a step for inactivating biofilm by bringing the biofilm into contact with the supercritical fluid. The biofilm using the supercritical fluid is exposed to the supercritical fluid in the state that it is not dipped in the aqueous medium and the moisture is adhered. The supercritical fluid comprises the supercritical carbon dioxide, and the supercritical nitrous oxide or their mixture fluid.
Abstract translation: 提供灭活生物膜的方法，其在短时间内使用超临界流体在改进的消毒功能中使生物膜失活。 使用超临界流体灭活生物膜的方法包括：用于定位在高压容器的表面中形成生物膜的物体的步骤; 以及通过使生物膜与超临界流体接触来灭活生物膜的步骤。 使用超临界流体的生物膜在不浸渍在水性介质中并且水分被粘附的状态下暴露于超临界流体。 超临界流体包括超临界二氧化碳和超临界一氧化二氮或其混合流体。
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25.发明授权
公开(公告)号：KR100841294B1
公开(公告)日：2008-06-25
申请号：KR1020060121650
申请日：2006-12-04
Applicant: 재단법인서울대학교산학협력재단
IPC: C07D307/30 , A61P31/04
CPC classification number: C07D405/12 , C07D307/32
Abstract: 쿼럼센싱 길항제로 기능을 하는 항균성 호모세린 락톤 유도체 및 이를 이용한 생물막의 형성 방지 방법에서, 항균성 호모세린 락톤 유도체는 호모세린 락톤 잔기와 설파닐 에타노일기(sulfanyl ethanoyl group)를 포함한다. 항균성 호모세린 락톤 유도체는 세균들이 의사소통을 위하여 신호전달 물질로 이용하는 화합물과 유사한 화학적 구조를 가지며, 세균들 간의 의사소통을 방해하는 쿼럼센싱 길항제(quorum sensing antagonist)로 기능을 한다. 이에 따라 항균성 호모세린 락톤 유도체는 미생물의 번식과 생물막의 형성을 효과적으로 차단할 수 있다.
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26.发明公开
公开(公告)号：KR1020080050844A
公开(公告)日：2008-06-10
申请号：KR1020060121650
申请日：2006-12-04
Applicant: 재단법인서울대학교산학협력재단
IPC: C07D307/30 , A61P31/04
CPC classification number: C07D405/12 , C07D307/32
Abstract: A homoserine lactone derivative is provided to inhibit quorum sensing, and prevent formation of biofilm and propagation of microorganisms by inhibiting gene expression of microorganisms, so that the compound is useful for inhibiting bacterial infection and biofilm formation in various life articles and medicinal instruments. A homoserine lactone derivative represented by the formula(1) or formula(2) is useful as a quorum sensing antagonist, wherein n is an integer from 0 to 10; R1 is hydrogen atom, carboxy group, aromatic hydrocarbon group containing nitrogen as a hetero atom or C1-C10 carboxyalkylthio group; R2 is aromatic hydrocarbon group or C1-C10 carboxyalkylthio group. The formation of biofilm of a microorganism such as Gram negative bacterium or Vibrio fischeri is prevented by contacting the homoserine lactone derivative represented by the formula(1) or formula(2) with the microorganism.
Abstract translation: 提供高丝氨酸内酯衍生物以抑制群体感应，并通过抑制微生物的基因表达来防止生物膜的形成和微生物的繁殖，使得该化合物可用于抑制各种生命制品和药物仪器中的细菌感染和生物膜形成。 由式（1）或式（2）表示的高丝氨酸内酯衍生物可用作群体感应拮抗剂，其中n为0至10的整数; R1是氢原子，羧基，含有氮原子的芳香族烃基或C1-C10羧烷基硫基; R2是芳族烃基或C1-C10羧烷基硫基。 通过使由式（1）或式（2）表示的高丝氨酸内酯衍生物与微生物接触，可以防止微生物如革兰氏阴性细菌或弧菌的生物膜的形成。
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公开(公告)号：KR1020080049527A
公开(公告)日：2008-06-04
申请号：KR1020060120182
申请日：2006-11-30
Applicant: 재단법인서울대학교산학협력재단
IPC: C07D307/30 , A61P31/04
Abstract: An antibacterial homoserine lactone derivative is provided to show excellent capability as a quorum sensing antagonist, thereby effectively blocking formation of a bio-film and inhibiting propagation of bacteria. An antibacterial homoserine lactone derivative is represented by a formula(1), wherein X is OH or thiol; n is an integer from 1 to 10; and R is H, halogen, thiol, C1-10 alkoxy, C1-10 alkylamino, C1-10 cycloalkylamino, C1-10 hydroxyalkylamino, morpholino, piperazinyl or hydroxyalkyl piperazinyl. A method for preventing formation of a biofilm comprises a step of contacting the homoserine lactone derivative with microorganism such as Gram negative bacteria.
Abstract translation: 提供抗菌高丝氨酸内酯衍生物以显示出优异的作为群体感应拮抗剂的能力，从而有效阻断生物膜的形成并抑制细菌繁殖。 抗菌高丝氨酸内酯衍生物由式（1）表示，其中X是OH或硫醇; n是1至10的整数; 且R为H，卤素，硫醇，C 1-10烷氧基，C 1-10烷基氨基，C 1-10环烷基氨基，C 1-10羟烷基氨基，吗啉代，哌嗪基或羟基烷基哌嗪基。 防止生物膜形成的方法包括将高丝氨酸内酯衍生物与革兰氏阴性细菌等微生物接触的步骤。
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