섬유아세포성장인자-2 를 이용한 면역 보강제
    24.
    发明公开
    섬유아세포성장인자-2 를 이용한 면역 보강제 无效
    免疫调节剂使用纤维生长因子-2

    公开(公告)号:KR1020130141878A

    公开(公告)日:2013-12-27

    申请号:KR1020120064958

    申请日:2012-06-18

    Abstract: The present invention relates to an immunity reinforcing composition which contains recombined fibrobalst growth factor-2 (FGF2) as an active ingredient and is capable of containing antigens. The composition of the present invention can be used as a pharmaceutical composition and a vaccine composition for preventing or treating: infectious diseases caused by virus, bacteria, fungi, or protozoa; or inflammation diseases caused by extracellular endoplasmic reticulum secreted from the bacteria, fungi, or protozoa.

    Abstract translation: 本发明涉及含有重组的纤维素生长因子-2(FGF2)作为活性成分并能够含有抗原的免疫增强组合物。 本发明的组合物可以用作药物组合物和用于预防或治疗由病毒,细菌,真菌或原生动物引起的感染性疾病的疫苗组合物; 或由细菌,真菌或原生动物分泌的细胞外质网引起的炎症疾病。

    배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법
    26.
    发明公开
    배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법 有权
    使用衍生自胚胎干细胞的微泡制备诱导性多能干细胞的方法

    公开(公告)号:KR1020120123624A

    公开(公告)日:2012-11-09

    申请号:KR1020110040202

    申请日:2011-04-28

    CPC classification number: C12N5/0696 A61K35/545 C12N2502/02 C12N2506/13

    Abstract: PURPOSE: A method for preparing induced pluripotent stem cells by treating a composition containing a microvesicle is provided to develop cell therapeutic agent. CONSTITUTION: A method for preparing induced pluripotent stem cells comprises a step of treating somatic cells with a composition containing embryonic stem cell-derived microvesicle. The embryonic stem cells are derived from human or non-human primates, mouse, rat, dog, cat, house, or horse. The microvesicle additionally contains components except for a cell membrane of embryonic stem cells. The components are cyclodextrin or polyethylene glycol. The composition additionally contains a component except for the microvesicle, such as BFA(brefeldin A), BIX(BiP inducer X), or VPA(valproic acid). A cell therapeutic agent contains the induced pluripotent stem cells. [Reference numerals] (AA) Embryonic stem cell; (BB) Microvesicle

    Abstract translation: 目的:提供一种通过处理含有微泡的组合物制备诱导性多能干细胞的方法,以开发细胞治疗剂。 构成:用于制备诱导性多能干细胞的方法包括用含有胚胎干细胞衍生的微泡的组合物处理体细胞的步骤。 胚胎干细胞衍生自人或非人灵长类动物,小鼠,大鼠,狗,猫,家或马。 微泡除了胚胎干细胞的细胞膜外,还含有成分。 组分是环糊精或聚乙二醇。 该组合物另外含有除了微泡之外的组分,例如BFA(布雷菲德菌素A),BIX(BiP诱导剂X)或VPA(丙戊酸))。 细胞治疗剂含有诱导的多能干细胞。 (附图标记)(AA)胚胎干细胞; (BB)微囊泡

    유산균 배양액 추출물을 포함하는 염증관련질환 치료용 조성물
    27.
    发明公开
    유산균 배양액 추출물을 포함하는 염증관련질환 치료용 조성물 无效
    用于治疗包含来自酸性细菌培养物的提取物的相关疾病的组合物

    公开(公告)号:KR1020110124516A

    公开(公告)日:2011-11-17

    申请号:KR1020100043934

    申请日:2010-05-11

    Abstract: PURPOSE: A composition containing extract isolated from lactic acid bacteria culture liquid is provided to suppress IL-6 secretion and to treat inflammatory diseases and cancer. CONSTITUTION: A composition for treating inflammatory diseases contains extract of lactic acid bacteria culture liquid. The lactic acid bacteria are Lactobacillus, Lactococcus, Leukonostoc, Pediococcus, or Bifidobacteria. The extract contains supernatant of the culture liquid except for the bacteria. The supernatant contains heat resistant ingredients. A composition for treating cancer contains the extract. A composition for treating thrombokinesis-related diseases contains the extract. A method for treating inflammatory diseases or cancer comprises a step of administering the extract.

    Abstract translation: 目的:提供一种含有从乳酸菌培养液中分离的提取物的组合物,以抑制IL-6的分泌并治疗炎性疾病和癌症。 构成:用于治疗炎性疾病的组合物含有乳酸菌培养液提取物。 乳酸菌是乳杆菌属,乳球菌属,白假单胞菌属,小球菌属或双歧杆菌属。 提取物含有除细菌以外的培养液的上清液。 上清液含有耐热成分。 用于治疗癌症的组合物含有提取物。 用于治疗血栓栓塞相关疾病的组合物含有提取物。 一种治疗炎性疾病或癌症的方法包括给药提取物的步骤。

    미량 원소 함량이 증가된 벼 품종 및 이를 이용한 기능성 식품
    28.
    发明公开
    미량 원소 함량이 증가된 벼 품종 및 이를 이용한 기능성 식품 有权
    具有增强金属内容和功能食品的米饭

    公开(公告)号:KR1020110065863A

    公开(公告)日:2011-06-16

    申请号:KR1020090122543

    申请日:2009-12-10

    CPC classification number: C12N15/8243 A23L7/196 A23L33/105

    Abstract: PURPOSE: A transgenic plant with enhanced trace element content by OsNAS2 gene activation is provided to grow the plants under the condition of lack heavy metal or excessive heave metal. CONSTITUTION: A plant with enhanced trace element content of iron, zinc, or copper has overexpressed OsNAS2 gene. The plant is Oriza sativa, barley, or corn. The expression of OsNAS2 is increases by insertion of an enhancer at the upstream or downstream of OsNAS2 gene. A method for preparing the plant with enhanced trace element content comprises: a step of introducing a structure containing a foreign enhancer into a plant, and a step of collecting a plant in which OsNAS2 gene is overexpressed.

    Abstract translation: 目的:提供通过OsNAS2基因激活提高微量元素含量的转基因植物,在缺乏重金属或过度沉积金属的条件下生长植物。 构成:具有铁,锌或铜的微量元素含量增加的植物已经过量表达OsNAS2基因。 该植物是玉蜀黍,大麦或玉米。 通过在OsNAS2基因的上游或下游插入增强子,OsNAS2的表达增加。 制备具有增强的微量元素含量的植物的方法包括:将含有外源增强子的结构引入植物的步骤,以及收集OsNAS2基因过表达的植物的步骤。

    유도성 일산화질소 합성효소 억제제를 포함하는 약학적 조성물 및 이의 용도
    29.
    发明公开
    유도성 일산화질소 합성효소 억제제를 포함하는 약학적 조성물 및 이의 용도 无效
    包含可溶性氮氧化物合成酶抑制剂的药物组合物及其用途

    公开(公告)号:KR1020110025081A

    公开(公告)日:2011-03-09

    申请号:KR1020100079691

    申请日:2010-08-18

    Abstract: PURPOSE: A pharmaceutical composition containing an inhibitor of inducible nitric oxide synthase is provided to treat severe inflammatory respiratory diseases. CONSTITUTION: A pharmaceutical composition for treating or preventing severe inflammatory diseases contains an inhibitor of inducible nitric oxide synthetase as an active ingredient. The severe inflammatory diseases are severe asthma or chronic obstructive lung diseases. The severe inflammatory disease is prevented or treated by administering to topical or whole body of mammal.

    Abstract translation: 目的:提供含有诱导型一氧化氮合酶抑制剂的药物组合物,用于治疗严重的炎症性呼吸道疾病。 构成:用于治疗或预防严重炎性疾病的药物组合物含有诱导型一氧化氮合成酶作为有效成分的抑制剂。 严重的炎性疾病是严重的哮喘或慢性阻塞性肺疾病。 通过给予哺乳动物的局部或全身来预防或治疗严重的炎性疾病。

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