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公开(公告)号：KR101372325B1
公开(公告)日：2014-03-13
申请号：KR1020110021514
申请日：2011-03-10
Applicant: 한국과학기술연구원
IPC: C07D311/36 , C07D493/04 , A61K36/60 , A61K31/352
Abstract: 본 발명은 상기한 문제점을 해결하기 위한 꾸지뽕으로부터 주요 프레닐레이티드 플라보노이드를 분리하는 방법으로서, 원심분리 분배 크로마토그래피( centrifugal partition chromatography)를 사용하여 적은양의 용매와 보다 적은 노동력으로 꾸지뽕으로부터 주요 프레닐레이티드 플라보노이드를 분리하는 방법을 제공한다.
CPC는 분리하고자 하는 물질이 다양한 용매의 조성으로 이루어진 섞이지 않는 두층의 용매에 대한 친화력을 이용하여 물질을 분리하는 방법으로, 물질을 분리하는데 있어 고체의 고정상을 사용하지 않기 때문에 시료의 손실이 없고, 고가의 용매를 다량사용하지 않아도 되기 때문에 경제적이다. 따라서, 본 발명은 꾸지뽕의 주요 물질인 6,8-디프레닐오로볼(6,8-diprenylorobol), 6,8-디프레닐게니스테인(6,8-diprenylgenistein) 또는 4´-
O -메틸알피눔이소플라본(4´-
O -methylalpinumisoflavone)와 같은 프레닐레이티드 플라보노이드의 대량생산을 가능하게 하여, 식품분야, 의학분야, 산업분야에서의 활용 가능성을 넓힐 수 있다.-
公开(公告)号：KR1020130084384A
公开(公告)日：2013-07-25
申请号：KR1020120005111
申请日：2012-01-17
Applicant: 한국과학기술연구원
Abstract: PURPOSE: An extracting method of a pine tree bark extract using an accelerated solvent etraction is provided to improve extracting rate, to increase antioxidant ingredients contained in the extract, and to diversify the kind of antioxidant ingredients. CONSTITUTION: An extracting method of a pine tree bark extract comprises the step of: processing a subcritical solvent in pine tree bark. The solvent is obtained by treating a mixture of water and ethanol at 150-250 deg. C. The volume ratio of the mixture of water and ethanol is 0.1-10:1. The pine tree is pini koraiensis radix, pinus densiflora, or forma erecta. [Reference numerals] (AA) Comparing rate of the bark of pine tree extract; (BB) Extraction yield (%); (CC) Hot water extract; (DD) Solvent pressurizing extract; (EE) Extract method
Abstract translation: 目的：提供采用加速溶剂萃取法的松树皮提取物的提取方法，提高提取率，增加提取物中含有的抗氧化成分，提高抗氧化成分的种类。 构成：松树皮提取物的提取方法包括以下步骤：在松树皮中加工亚临界溶剂。 溶剂通过在150-250度处理水和乙醇的混合物而获得。 C.水和乙醇的混合物的体积比为0.1-10:1。 松树是pini koraiensis radix，pinia densiflora或forma erecta。 （附图标记）（AA）松树提取物的树皮的比较率; （BB）提取率（％）; （CC）热水提取物; （DD）溶剂加压提取物; （EE）提取方法
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23.发明授权돌단풍 추출물 또는 이의 분획물을 유효성분으로 함유하는 폐경기 증후군 예방 및 치료용 조성물 有权用于预防和治疗含有Aceriphyllum rossii的提取物或部分的绝经后综合征作为有效成分的组合物
公开(公告)号：KR101075554B1
公开(公告)日：2011-10-21
申请号：KR1020100017312
申请日：2010-02-25
Applicant: 한국과학기술연구원
CPC classification number: A61K36/185
Abstract: 본발명은돌단풍추출물또는이의분획물을유효성분으로함유하는여성폐경기증후군예방및 치료용조성물에관한것으로, 보다상세하게는물, 알코올또는이들의혼합용매로추출한돌단풍()의추출물또는이의분획물이에스트로겐반응부위(Estrogen Responsive Element; ERE)를포함하는프로모터의발현을촉진하고, 인간유방조직유래세포주인 MCF-7의생장을촉진하여에스트로겐활성을갖는물질임을확인하고, 조골세포의분화촉진효과를가짐을확인함으로써, 에스트로겐결핍에의해발생하는안면홍조증, 골다공증및 정맥혈전증등과같은여성폐경기증후군예방및 치료용조성물로유용하게사용될수 있다.
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公开(公告)号：KR1020090041533A
公开(公告)日：2009-04-29
申请号：KR1020070107087
申请日：2007-10-24
Applicant: 한국과학기술연구원
IPC: A61K36/185 , A61K8/97 , A61P17/18 , A61Q19/08
CPC classification number: A61K36/185
Abstract: A composition containing Chamaenerion angustifolium extract with anti-wrinkle and antioxidant activities is provided to show wrinkle and elasticity improvement by the Chamaenerion angustifolium extracts having effects of inhibiting type I collagenase and AP-1. A composition containing Chamaenerion angustifolium extract with anti-wrinkle and antioxidant activities comprises Chamaenerion angustifolium extract obtained by adding water and alcohol or a mixed solvent thereof. The Chamaenerion angustifolium extract inhibits inflammation and improves skin elasticity. The composition has a formulation of external skin application. The composition represents cosmetics or health foods. The Chamaenerion angustifolium extract is an active ingredient in the composition.
Abstract translation: 提供了具有抗皱和抗氧化活性的含有Chamaenerion angustifolium提取物的组合物，以显示具有抑制I型胶原酶和AP-1的作用的Chamaenerion angustifolium提取物的皱纹和弹性改善。 具有抗皱和抗氧化活性的含有尖角鳗提取物的组合物包括通过加入水和醇或其混合溶剂获得的Challenerion angustifolium提取物。 Chamaenerion angustifolium提取物抑制炎症并改善皮肤弹性。 该组合物具有外用皮肤应用的配方。 组合物代表化妆品或保健食品。 Chamaenerion angustifolium提取物是组合物中的活性成分。
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公开(公告)号：KR1020090041531A
公开(公告)日：2009-04-29
申请号：KR1020070107085
申请日：2007-10-24
Applicant: 한국과학기술연구원
IPC: A61K36/185 , A61K8/97 , A61P39/06 , A61Q19/08
CPC classification number: A61K36/45 , A23L2/02 , A23L2/52 , A23L33/105 , A61K8/97 , A61K9/0095 , A61K9/1617 , A61K9/1623 , A61K9/2018 , A61K9/2059 , A61K2800/522 , A61K2800/782 , A61Q19/08
Abstract: A composition containing Ortilia secunda extracts is provided to show wrinkle and elasticity improvement by the Ortilia secunda extracts having effects of inhibiting type I collagenase and AP-1 and increasing generation of collagen while suppressing decomposition of the collagen. A composition for wrinkle improvement comprises Ortilia secunda extracts obtained by adding water and C1-C4 low alcohol such as ethanol and methanol or mixed solvents thereof. The Ortilia secunda extracts are active ingredients in the composition for wrinkle improvement. The Ortilia secunda extracts eliminate radicals. The composition has a formulation of external skin application. The composition for wrinkle improvement represents antioxidant.
Abstract translation: 提供含有Ortilia secunda提取物的组合物，以显示具有抑制I型胶原酶和AP-1的作用的Ortilia secunda提取物的皱纹和弹性改善，并增加胶原蛋白的产生，同时抑制胶原蛋白的分解。 用于皱纹改良的组合物包括通过加入水和C1-C4低级醇如乙醇和甲醇或其混合溶剂获得的Ortilia secunda提取物。 Ortilia secunda提取物是用于皱纹改善的组合物中的活性成分。 Ortilia secunda提取物消除自由基。 该组合物具有外用皮肤应用的配方。 用于皱纹改善的组合物表示抗氧化剂。
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Patent Agency Ranking
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公开(公告)号：KR101838142B1
公开(公告)日：2018-03-14
申请号：KR1020170047303
申请日：2017-04-12
Applicant: 한국과학기술연구원
IPC: A61K36/48 , A23L33/105
CPC classification number: A23L33/105 , A23V2002/00 , A23V2200/30 , A61K36/48 , Y10S514/912
Abstract: 본명세서에는쥐눈이콩추출물을유효성분으로포함하는각막질환의예방또는치료용약학조성물및 쥐눈이콩추출물을유효성분으로포함하는각막손상개선용건강식품조성물이개시된다. 상기쥐눈이콩추출물은각막세포손상을억제하고각막세포를보호하며, 안구건조증, 각막찰과상을예방, 개선또는치료하는효과가있다.
Abstract translation: 本文中公开了一种用于预防或治疗含有豆腐提取物作为活性成分的角膜疾病的药物组合物以及用于改善角膜损伤的健康食品组合物，其包含豆腐提取物作为活性成分。 上述提取物具有抑制角膜细胞损伤，保护角膜细胞，预防，改善或治疗干眼症和角膜磨损的作用。
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公开(公告)号：KR1020170023055A
公开(公告)日：2017-03-02
申请号：KR1020170023435
申请日：2017-02-22
Applicant: 한국과학기술연구원
IPC: A61K36/484 , A23L33/105
CPC classification number: A61K36/484 , A23L33/105
Abstract: 본명세서에는쥐눈이콩추출물을포함하는망막질환의예방또는치료용약학조성물및 쥐눈이콩추출물을포함하는망막질환의예방또는개선용식품조성물이개시된다.
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公开(公告)号：KR1020160082159A
公开(公告)日：2016-07-08
申请号：KR1020140195077
申请日：2014-12-31
Applicant: 한국과학기술연구원
CPC classification number: C11B9/022 , C11B9/0061
Abstract: 본발명은소나무로부터정유및 폴리페놀분획을연속추출하는소나무의가공방법에관한것이다.
Abstract translation: 本发明涉及一种从松树中连续提取精油和多酚馏分的松树处理方法，其中处理方法可以减少时间和能量。 从松树中连续提取精油和多酚馏分的松树的加工方法包括以下步骤：通过蒸汽蒸馏松木生产精油; 并通过在除去所得蒸馏后留下的热水提取物质获得多酚。
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公开(公告)号：KR1020130083283A
公开(公告)日：2013-07-22
申请号：KR1020120003970
申请日：2012-01-12
Applicant: 한국과학기술연구원
CPC classification number: A23L33/105 , A23L19/00 , A23V2002/00 , A23V2200/30 , A23V2250/21 , A23V2300/14 , A23V2300/20 , A23V2300/24
Abstract: PURPOSE: A method of improving the anti-oxidation ability of bamboo leaves is provided to heat process the bamboo leaves for improving anti-oxidation ability. CONSTITUTION: Bamboo leaves are heat-processed at 180-250°C for 5-20 minutes. The bamboo leaves are cooled at 5-35°C for 20-40 minutes. The bamboo leaves are obtained from more than one kind selected from a group consisting of Phyllostachys nigra Munro, Phyllostachys edulis, Phyllostachys bambusoides, Phyllostachys nigra var. henonis, Phyllostachys pubescens, Sasa borealis, and Sasa quelpaertensis Nakai. [Reference numerals] (AA) Before heat processing; (BB) After heat processing
Abstract translation: 目的：提高竹叶抗氧化能力的方法，对竹叶进行加热处理，提高抗氧化能力。 规定：竹叶在180-250℃下热处理5-20分钟。 竹叶在5-35℃冷却20-40分钟。 竹叶从多种选自Phyllostachys nigra Munro，Phyllostachys edulis，Phyllostachys bambusoides，Phyllostachys nigra var。 on is is，，。。。。。。。。。。。。。。。。。。。。。。。。。 （附图标记）（AA）热处理前; （BB）热处理后
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