公开(公告)号：JPH1194844A

公开(公告)日：1999-04-09

申请号：JP25955897

申请日：1997-09-25

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01N35/10

Abstract: PROBLEM TO BE SOLVED: To prevent splashing of a delivered residual liquid while improving a treating speed in the replacing of a nozzle chip of the analyzer for having an automatically dispensing function. SOLUTION: A pressure sensor 70 is provided to measure a pressure in a nozzle base part 52 into which is press-fitted a nozzle chip 54. A control part 80 controls the operation of pulling the nozzle chip 54 out of the nozzle base part 52, based on a pressure value to be outputted from the pressure sensor 70. The control part 80 detects that the pressure value begins to lower and switches the pulling out operation from a high speed to a low speed, which can prevent a sharp drop in the pressure within the nozzle chip 54 to block the fouling of the nozzle base part 52 as caused by the splashing of a delivered residual liquid. When detecting that the pressure value reaches an atmospheric pressure, the control part 80 judges that there is no risk of splashing to accelerate the pulling out operation. This allows a low speed operation only during a period when the risk of splashing remains possible and a high speed operation during the other periods thereby shortening the treating time.

公开(公告)号：JPH10206214A

公开(公告)日：1998-08-07

申请号：JP1111797

申请日：1997-01-24

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01F23/28 ,  G01N35/10

Abstract: PROBLEM TO BE SOLVED: To shorten a time for moving up and down a nozzle, by setting a plurality of light-measuring devices which detect transmission light quantity characteristics arranged in the longitudinal direction of the nozzle as partial characteristics in accordance with an up-down movement of the nozzle, coupling the obtained partial characteristics and forming a transmission light quantity characteristic of the whole nozzle. SOLUTION: A nozzle 8 is lowered by a driving mechanism 18 to suck and dispense a predetermined amount of a sample 7 in a sample container 6 into a nozzle chip 10. The nozzle 8 is then pulled up. A partial characteristic obtained by a first light- measuring unit 20 is temporarily stored in a first partial characteristic memory 32. Similarly, a partial characteristic obtained by a second light-measuring unit 22 is temporarily stored in a partial characteristic memory 34. A characteristic-coupling part 36 couples the partial characteristics stored in the memories 32, 34 thereby forming a transmission light quantity characteristic covering the whole of a characteristic detection range. The formed transmission light quantity characteristic is sent to an operating part 38, and stored in a memory part 40 if it is necessary. The operating part 38 compares two transmission light quantity characteristics before and after the sample 7 is sucked, thereby operating a suction amount.

公开(公告)号：JPH09264772A

公开(公告)日：1997-10-07

申请号：JP7492596

申请日：1996-03-28

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01F23/28 ,  G01N35/10

Abstract: PROBLEM TO BE SOLVED: To accurately calculate a suction amount and discharge amount by directly monitoring liquid level in a nozzle. SOLUTION: A nozzle 10 has a nozzle base 12 and a nozzle tip 14. An ultrasonic sensor 18 is provided at the base 12. The liquid level of sample in liquid is detected by the sensor 18. Since the ultrasonic wave is transmitted and received in the nozzle 10, the convergence of the ultrasonic wave can be enhanced, and external noise can be shut off. The suction amount and, discharge amount can be calculated, liquid leakage can be discriminated and suction failure is discriminated based on the level detected result.

公开(公告)号：JPH0979953A

公开(公告)日：1997-03-28

申请号：JP23540795

申请日：1995-09-13

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01N33/48 ,  A61B5/154 ,  G01N1/00 ,  G01N1/16 ,  A61B5/14

Abstract: PROBLEM TO BE SOLVED: To collect blood samples of a fixed quantity by repeatedly performing pressure reduction and opening to the air on an airtight space formed below a container placed on the outlet side of a sample collecting needle and setting the pressure reducing time within a range in which the collected amount of blood becomes proportional to time from the suction starting time, and then, setting the opening time at the period until the internal pressure of the space returns to the atmospheric pressure after space is opened to the air. SOLUTION: When a blood-collecting tube 16 is inserted into a coupler 14 from the above and continuously pressed down, the coupler 12 tightly comes into contact with a sampling container 18 and an airtight space is formed below a blood-collecting needle. A suction pump 46 reduces the internal pressure of the space and an open valve 42 opens the space to the air. A control section 50 controls the pump 46 and valve 42 and is provided with a timer A which controls the pressure reducing time and the airtight space opening time and another timer B which controls the elapsed time from the sampling starting time. Therefore, samples of a fixed quantity are collected by repeating basic steps of pressure reduction and opening to the air on the space by setting the pressure reducing time within a range within which the collected amount of blood becomes proportional to the elapsed time from the suction starting time and the airtight space opening time to the period from the opening time to the time at which the internal pressure of the space returns to the atmospheric pressure.

公开(公告)号：JPH08320318A

公开(公告)日：1996-12-03

申请号：JP12803795

申请日：1995-05-26

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01N33/48 ,  A61B5/15 ,  A61B5/154 ,  A61B5/14

Abstract: PURPOSE: To obtain a sampling apparatus by which a blood sample in the interior of a blood sampling tube is sampled efficiently and safely without removing a sealing stopper from the blood sampling tube. CONSTITUTION: A coupler 12 is mounted on a coupler base 10, and a blood sampling tube 14 after a centrifugal separation treatment is inserted into the coupler 12 in an inverted state. Thereby, a blood sampling needle 26 is pierced through a rubber stopper 22. A packing 40 is used to seal a part between the coupler base 10 and a sampling container 24 and to seal a part between the coupler 12 and the coupler base 10. When the air in the interior of the sampling container 24 is sucked, an air passage 36 functions as a ventilation passage, and a serum 20 is taken into the sampling container 24 via a sample passage 34. While the interior of the blood sampling tube 14 is being maintained always under atmospheric pressure or lower, the serum 20 is sampled.

公开(公告)号：JPH07198726A

公开(公告)日：1995-08-01

申请号：JP29858493

申请日：1993-11-29

Applicant: ALOKA CO LTD ,  ABBOTT LAB

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU ,  BURENTO ARAN PERITEIA

IPC: G01N35/10

Abstract: PURPOSE: To detect the abnormality of suction and discharge of specimen with high sensitivity, not depending on the viscosities of the specimen. CONSTITUTION: An automatic dispensing device for the suction and discharge of specimen 2 through a nozzle 4 has a pressure detector 8 to detect air pressure during suction and discharge of the specimen 2. A primary differential operation circuit 18 performs differential operation on waveforms output from the pressure detector 8 and a secondary differential operation circuit 20 performs differential operation on the result of the primary differential operation. A judgment circuit 24 compares the result of the secondary differential operation with two types of threshold values to judge abnormality. The result of the secondary differential operation shows the variation of the change rate of air pressure to allow accurate separate filling of the specimen with different viscosities, hardly depending on the viscosities of the specimen 2 as shown in the result of the primary differential operation. Since the inflection point of the air pressure change rate is accurately detected, judgement can be made with extremely high sensitivity.

公开(公告)号：JPH0777527A

公开(公告)日：1995-03-20

申请号：JP22239793

申请日：1993-09-07

Applicant: ALOKA CO LTD

Inventor： MORI SHIGEMITSU ,  TAKEDA MASAAKI ,  KOJO YOSHIYUKI ,  MATSUDA TORU

IPC: G01N1/00 ,  G01N1/16 ,  G01N33/48

Abstract: PURPOSE:To extract only the blood serum from a blood sampling tube containing blood after centrifugal separation by means of a single sampling needle. CONSTITUTION:A sampling needle 26 is set at the center of a blood sampling tube coupler 22 while piercing a rubber member 54 disposed at the center of a sealing plug 50. Pressure is increased and decreased repeatedly to a sampling container 14 thus sucking blood serum 18 therein through the sampling needle 22. A cleaning cap is employed for cleaning the blood sampling coupler 22.

公开(公告)号：JPH0735759A

公开(公告)日：1995-02-07

申请号：JP17870093

申请日：1993-07-20

Applicant: ALOKA CO LTD

Inventor： TAKEDA MASAAKI ,  MATSUDA TORU

IPC: G01N1/00 ,  G01N35/10

Abstract: PURPOSE:To provide a method for detecting a droplet wherein whether or not a droplet generated at the tip of a nozzle at dispensing time exists, and it dispenser. CONSTITUTION:A dispenser forms a light beam 20 by a near infrared light emitting diode 14, a lens 16 for converting the emitted near infrared light into a parallel light beam, and a cylindrical lens 18 for narrowing the parallel beam into a size in an axial direction of a chip 36, wherein the light beam 20 has an axis of the chip 36 and a beam width larger than a vertical width. Therefore if a droplet is generated from the tip of the chip 36, the droplet and the beam 20 cross each other. If a droplet detection circuit 26 receives a transmitted light amount at the time of movement of the chip 36 via an optical filter 22 at a light receiving part and a light detector 24 and senses a rapid change in the transmitted light amount level, it outputs a signal indicating 'generation of droplets' to a monitor 28 and issues a warning to a user by displaying a message indicating the generation of droplets.

公开(公告)号：JP2011058978A

公开(公告)日：2011-03-24

申请号：JP2009209716

申请日：2009-09-10

Applicant: Aloka Co Ltd ,  Hanawa Takao ,  アロカ株式会社 ,  塙 隆夫

Inventor： OZAWA YUKIKO ,  TAKASU TATSUYA ,  MATSUDA TORU

IPC: G01N35/10 ,  C25D9/02 ,  C25D13/00 ,  C25D13/12 ,  C25D13/22

Abstract: PROBLEM TO BE SOLVED: To provide a nozzle processing device capable of preventing or reducing adhesion of dirt onto a metal nozzle over a long period. SOLUTION: This nozzle processing device is loaded on an inspection analyzer in order to clean the metal nozzle 20 provided on the inspection analyzer for inspecting or analyzing a liquid specimen. The nozzle processing device includes: a nozzle unit 12 including the metal nozzle 20 used for sucking/discharging liquid; a processing tank 16 storing electrodeposition liquid; a moving mechanism for moving the metal nozzle 20 relatively to the processing tank, in order to proceed the metal nozzle 20 into the processing tank 16 to be dipped into the electrodeposition liquid; a linear electrode 40 positioned inside the metal nozzle 20 proceeded into the processing tank 16; and a constant voltage power supply 70 for applying a voltage to the linear electrode 40 and the metal nozzle 20, in order to send a DC current therebetween, and to deposit a coating film component included in the electrodeposition liquid. A surface coating of the metal nozzle 20 is repaired or generated by voltage application. COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够长时间地防止或减少金属喷嘴上的污垢附着的喷嘴加工装置。

解决方案：该喷嘴处理装置装载在检查分析装置上，以清洁检查分析装置上设置的金属喷嘴20，以检查或分析液体试样。 喷嘴处理装置包括：喷嘴单元12，其包括用于吸入/排出液体的金属喷嘴20; 储存电沉积液的处理槽16; 用于使金属喷嘴20相对于处理槽移动的移动机构，以便将金属喷嘴20进入处理槽16以浸入电沉积液中; 位于金属喷嘴20内的线状电极40进入处理槽16; 以及用于向直线电极40和金属喷嘴20施加电压以便在其间发送DC电流并且沉积包含在电沉积液中的涂膜组分的恒压电源70。 金属喷嘴20的表面涂层由电压施加而修复或产生。 版权所有（C）2011，JPO＆INPIT

公开(公告)号：JP2011056422A

公开(公告)日：2011-03-24

申请号：JP2009209715

申请日：2009-09-10

Applicant: Aloka Co Ltd ,  アロカ株式会社

Inventor： OZAWA YUKIKO ,  SATO TAKASHI ,  OGAWA KOJI ,  MATSUDA TORU ,  TAKASU TATSUYA

IPC: B08B3/08 ,  B05C11/00 ,  C25F1/00

Abstract: PROBLEM TO BE SOLVED: To provide a nozzle washing apparatus which can wash powerfully a metallic nozzle more easily.
SOLUTION: The nozzle washing apparatus is mounted on inspection and analysis equipment to wash the metallic nozzle 20 provided on the inspection and analysis equipment inspecting or analyzing a liquid specimen. The nozzle washing apparatus comprises a nozzle unit 12 provided with the metallic nozzle 20 used for suction and discharge of a liquid, a treatment tank 16 in which a hydrogen peroxide solution is stored in performing the washing, a movement mechanism relatively moving the metallic nozzle 20 to the treatment tank to make the metallic nozzle 20 go into the treatment tank 16 to dip it in the hydrogen peroxide solution in performing the washing, a linear electrode 40 positioned on the inside of the metallic nozzle 20 penetrated into the treatment tank 16, and a constant-voltage power supply 70 applying a positive voltage to the hydrogen peroxide solution and a negative voltage to the metallic nozzle 20 through the linear electrode 40. The metallic nozzle 20 is washed by hydroxyl radicals produced in applying the voltage.
COPYRIGHT: (C)2011,JPO&INPIT

Abstract translation: 要解决的问题：提供一种能够更容易地对金属喷嘴进行强力洗涤的喷嘴清洗装置。

解决方案：喷嘴清洗装置安装在检查和分析设备上，以清洗检查和分析设备上检测或分析液体样本的金属喷嘴20。 喷嘴清洗装置包括设置有用于抽吸和排出液体的金属喷嘴20的喷嘴单元12，在执行洗涤时存储过氧化氢溶液的处理槽16，使金属喷嘴20相对移动的移动机构 到处理槽中，使金属喷嘴20进入处理槽16，在进行洗涤时将其浸渍在过氧化氢溶液中，位于金属喷嘴20的内部的线状电极40贯穿处理槽16， 恒压电源70通过线性电极40向金属喷嘴20施加正电压至负载电压。金属喷嘴20由施加电压而产生的羟基自由基洗涤。 版权所有（C）2011，JPO＆INPIT