公开(公告)号：WO1993017128A1

公开(公告)日：1993-09-02

申请号：PCT/US1993001718

申请日：1993-02-25

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  TARON, Douglas, J.

IPC: C12Q01/68

CPC classification number: C12Q1/6841 ,  G01N33/58

Abstract: Methods and reagents for the in situ detection of chromosome structure or a region of a chromosome involved in rearrangements are disclosed. These reagents include a multiplicity of labeled probe DNA sequences that are complementary to different portions of the chromosome or chromosome region to be detected, and label specific antibodies conjugated to interdependent signal producing moieties. Selected pairs of the probes are contacted under hybridizing conditions with the chromosome or chromosome region of interest. Subsequently, said label specific antibodies are attached to the labels, resulting in the coupling of said moieties chemical reactions upon the addition of substrates. Consequently, a signal is produced at the chromosome region of interest that can be detected by optical means.

Abstract translation: 公开了原位检测染色体结构或涉及重排染色体区域的方法和试剂。 这些试剂包括与待检测的染色体或染色体区域的不同部分互补的多个标记的探针DNA序列，以及与相互依赖的信号产生部分缀合的标记特异性抗体。 选择的探针对在杂交条件下与感兴趣的染色体或染色体区域接触。 随后，所述标记特异性抗体连接到标记上，导致在添加底物时所述部分化学反应的偶联。 因此，可以通过光学手段检测到的感兴趣的染色体区域产生信号。

公开(公告)号：WO1993016511A1

公开(公告)日：1993-08-19

申请号：PCT/US1993001101

申请日：1993-02-08

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  GRUBB, Stephen, G.

IPC: H01S03/06

CPC classification number: H01S3/094003 ,  H01S3/094092 ,  H01S3/17

Abstract: Methods and apparatus for upconverting laser sources and amplifiers that use solid state components throughout and achieve such operation with a continuous or quasi-continuous single band infrared pumping source using successive energy transfers between the pumping radiation and activator in the host of the lasant upconversion material under ordinary operating conditions.

公开(公告)号：WO1993015536A1

公开(公告)日：1993-08-05

申请号：PCT/US1993000887

申请日：1993-02-01

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  MINELLY, John, D. ,  TAYLOR, Elizabeth, R.

IPC: H01S03/06

CPC classification number: H01S3/094003 ,  C03B37/01205 ,  C03B2201/30 ,  C03B2201/50 ,  C03B2203/12 ,  G02B6/4206 ,  H01S3/06708 ,  H01S3/06729 ,  H01S3/06745 ,  H01S3/08045 ,  H01S3/094007 ,  H01S3/094019 ,  H01S3/094069

Abstract: A compound glass fibre fabricated from lead-silicate glasses that comprises an outer cladding, an inner cladding with a cross-sectional profile optimized for receiving multimode pumping radiation, and a single-mode central core within said inner cladding that is doped with a lasant material to maximize transfer of said multimode pumping radiation to said single mode doped core.

Abstract translation: 由硅酸盐玻璃制成的复合玻璃纤维，其包括外包层，具有优化用于接收多模泵浦辐射的横截面轮廓的内包层，以及在所述内包层内掺杂有惰性材料的单模中心纤芯 以将所述多模式泵浦辐射的转移最大化到所述单模掺杂核心。

公开(公告)号：WO1993004144A1

公开(公告)日：1993-03-04

申请号：PCT/US1991005868

申请日：1991-08-19

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  KRUSE, Larry, Wilfred

IPC: C10G11/00

CPC classification number: C10G11/18

Abstract: A catalytic cracking process is provided for cost effectively separating and stripping hydrocarbon from catalyst while limiting the occurrence of undesired catalytic overcracking and thermal cracking reactions. The process includes the steps of contacting feed with catalyst, grossly separating the larger coked catalyst particles from the hydrocarbon, disengaging the smaller coked catalyst fines from the hydrocarbon, removing volatile hydrocarbon from the grossly separated and disengaged catalyst, and recycling the volatile hydrocarbon back to the gross separating step. The disengager step includes the steps of dampening the flow of grossly separated hydrocarbon and internally cyclone separating the smaller catalyst fines from the hydrocarbon product.

Abstract translation: 提供了一种催化裂化方法，用于成本有效地从催化剂中分离和汽提烃，同时限制了不期望的催化过度裂解和热裂解反应的发生。 该方法包括以下步骤：使进料与催化剂接触，将较大的焦化催化剂颗粒与烃分离，将较小的焦化催化剂细粒与烃脱离，从大量分离和分离的催化剂中除去挥发性烃，并将挥发性烃再循环回 总分离步骤。 分离步骤包括抑制严重分离的烃和内部旋流器的流动的步骤，将较小的催化剂细粉与烃产物分离。

公开(公告)号：WO1993003187A2

公开(公告)日：1993-02-18

申请号：PCT/US1992006617

申请日：1992-07-28

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  PARODOS, Kyriaki ,  McCARTY, Janice, Marie

IPC: C12Q01/68

CPC classification number: C12Q1/689 ,  C12Q1/6813

Abstract: The invention relates to methods of detection of bacteria of the genus Shigella and/or Enteroinvasive E. coli (EIEC) by use of a set of nucleic acid probes. The invention further relates to a set of Shigella specific chromosomal sequences and fragments and to probes derived from the Shigella specific fragments. Additionally, probes were derived from a sequence from the Shigella ompA gene. In particular, a series of probes, each approximately 40 nucleotides in length, were designed having specificity for Shigella or for Shigella and Enteroinvasive E. coli, and having utility in nonisotopic test formats which require amplification to achieve high sensitivity. Specific hybridization probe sets which are capable of detecting substantially all clinically significant serotypes of Shigella, as well as enteroinvasive strains of E. coli, are disclosed.

Abstract translation: 本发明涉及通过使用一组核酸探针检测志贺氏菌属和/或肠内侵袭性大肠杆菌（EIEC）的细菌的方法。 本发明还涉及一组志贺氏菌特异性染色体序列和片段以及源自志贺氏菌特异性片段的探针。 此外，探针源自志贺氏菌ompA基因的序列。 特别地，设计了长度为约40个核苷酸的一系列探针，其具有对志贺氏菌或志贺氏菌和肠内浸润型大肠杆菌的特异性，并且在需要扩增以实现高灵敏度的非同位素测试形式中具有应用。 公开了能够检测志贺氏菌的基本上所有临床显着血清型的特异性杂交探针组，以及大肠杆菌的肠侵袭性菌株。

公开(公告)号：WO1992018454A1

公开(公告)日：1992-10-29

申请号：PCT/US1992002910

申请日：1992-04-09

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  STREICH, Debra, Jean ,  GRAZIANO, Diane, Jean ,  SCHILLER, Sandra, K. ,  GRIMM, Roger, John

IPC: C07C51/43

CPC classification number: C07F9/46 ,  C07C51/43 ,  C07C63/26

Abstract: A process is disclosed for preparation of purified terephthalic acid containing 200 ppmw or less of p-toluic acid. A filter cake of purified terephthalic acid is prepared by filtering, under a differential pressure of about or greater than 0.5 psi over the system pressure and a temperature within the range of from about 100 DEG C to about 205 DEG C, an aqueous slurry of purified terephthalic acid containing a solution of p-toluic acid. The aqueous solution of p-toluic acid remaining in the filter cake of purified terephthalic acid is displaced from the filter cake by water under a pressure gradient over the system pressure at a temperature within the range of from about 100 DEG C to about 205 DEG C. Pressure flash evaporation of water remaining in the filter cake occurs upon release of the system pressure to lower pressure with consequent lower temperature. The crystalline terephthalic acid product containing 200 ppmw or less p-toluic acid can be dried under atmospheric pressure. Purified terephthalic acid is useful for the manufacture of polyesters from which clothing and related goods are made.

Abstract translation: 公开了一种制备含有200ppmw或更少的对甲苯甲酸的纯对苯二甲酸的方法。 纯化的对苯二甲酸的滤饼通过在系统压力和约100℃至约205℃范围内的温度下在约或大于0.5psi的压差下过滤来制备，纯化的 对苯二甲酸含有对甲苯甲酸的溶液。 保留在纯化的对苯二甲酸的滤饼中的对甲苯甲酸的水溶液在压力梯度下在压力梯度下在约100℃至约205℃的温度范围内从水中从滤饼中移出 当将系统压力释放到较低压力并随之降低温度时，残留在滤饼中的水的压力闪蒸蒸发发生。 含有200ppmw以下的对甲苯甲酸的结晶对苯二甲酸产物可以在大气压下干燥。 纯化的对苯二甲酸可用于制造服装和相关商品的聚酯。

公开(公告)号：WO1992018453A1

公开(公告)日：1992-10-29

申请号：PCT/US1992002909

申请日：1992-04-09

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  GEE, John, Charles ,  ROSENFELD, Jeffrey, Ira ,  BARTOS, Thomas, Michael

IPC: C07C51/43

CPC classification number: C07C51/43 ,  C07C63/26

Abstract: A process is disclosed for counter-current positive displacement of an aliphatic carboxylic acid of 1 to 5 carbon atoms from a filter cake of an aromatic polycarboxylic acid containing the aliphatic carboxylic acid wherein mother liquor retained by the aromatic polycarboxylic acid has a concentration of the aliphatic carboxylic acid of 5000 ppmw, or less, based upon weight of the aromatic polycarboxylic acid present. This method is useful for the manufacture of crude terephthalic acid which is used after purification for the preparation of polyesters used for the manufacture of fabrics, fibers and plastics bottles.

Abstract translation: 公开了从含有脂肪族羧酸的芳香族多元羧酸的滤饼中逆向正位移1〜5个碳原子的脂肪族羧酸的方法，其中由芳族多元羧酸保留的母液具有脂族 基于存在的芳族多元羧酸的重量，5000ppmw或更低的羧酸。 该方法可用于制造用于制备用于制造织物，纤维和塑料瓶的聚酯的纯化后的粗对苯二甲酸。

公开(公告)号：WO1992015883A1

公开(公告)日：1992-09-17

申请号：PCT/US1992001617

申请日：1992-03-04

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  FOSTER, Kimberly, A. ,  BOTTARI, Donna ,  GARRAMONE, Susan

IPC: G01N33/531

CPC classification number: G01N33/531 ,  C12Q1/6816 ,  C12Q1/689 ,  G01N33/56916

Abstract: The disclosure relates to the inclusion of one or more colored organic compounds in reaction reagents to be used in an assay for the detection of microorganisms. The colored organic compounds can be acid/base indicator compounds, or colored organic compounds having a color which is not pH sensitive.

Abstract translation: 本公开涉及将一种或多种着色有机化合物包含在用于检测微生物的测定中的反应试剂中。 有色有机化合物可以是酸/碱指示剂化合物或具有不敏感颜色的着色有机化合物。

公开(公告)号：WO1991013078A1

公开(公告)日：1991-09-05

申请号：PCT/US1991001458

申请日：1991-03-04

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  AUSICH, Rodney, Lee ,  BRINKHAUS, Friedhelm, Luetke ,  MUKHARJI, Indrani ,  PROFFITT, John, Houston ,  YARGER, James, Gregory ,  YEN, Huei-Che, Bill

IPC: C07H15/12

CPC classification number: C12N9/0004 ,  C12N15/52 ,  C12N15/74 ,  C12N15/81 ,  C12N15/825 ,  C12P23/00 ,  Y10S435/847

Abstract: DNA segments encoding the Erwinia herbicola enzymes geranylgeranyl pyrophosphate (GGPP) synthase, phytoene synthase, phytoene dehydrogenase-4H, lycopene cyclase, beta-carotene hydroxylase, and zeaxanthin glycosylase and DNA variants thereof encoding an enzyme having substantially the same biologically activity, vectors containing those DNA segments, host cells containing the vectors and methods for producing those enzymes, a method for protecting plants from the herbicide norflurazon, as well as methods for producing GGPP and the carotenoids phytoene, lycopene, beta -carotene, zeaxanthin and zeaxanthin diglucoside by recombinant DNA technology in tranformed host organisms are disclosed.

Abstract translation: 编码具有基本上相同生物学活性的酶的欧文氏菌除草剂er牛儿基焦磷酸（GGPP）合酶，八氢番茄红素合成酶，八氢番茄红素脱氢酶-4H，番茄红素环化酶，β-胡萝卜素羟化酶和玉米黄质糖基化酶及其DNA变体的DNA片段， DNA片段，含有载体的宿主细胞和用于制备这些酶的方法，用于从除草剂诺氟拉for保护植物的方法，以及通过重组DNA产生GGPP和类胡萝卜素亚苄基番茄红素，番茄红素，β-胡萝卜素，玉米黄质和玉米黄质二葡萄糖苷的方法 披露了转化的宿主生物中的技术。

公开(公告)号：WO1990010963A1

公开(公告)日：1990-09-20

申请号：PCT/US1990001311

申请日：1990-03-09

Applicant: AMOCO CORPORATION

Inventor： AMOCO CORPORATION ,  FISHER, James, Harmon ,  CLARK, John, Hamilton ,  WOLFRAM, Thomas

IPC: H01S03/04

CPC classification number: H01S5/02415 ,  H01S5/0014 ,  H01S5/02212 ,  H01S5/32325

Abstract: The optical output power from a GaInP based laser diode (1) can be at least doubled by slight cooling of the device with thermoelectric cooling means (17) when the diode (1) is operated in a substantially room temperature environment.