公开(公告)号：CA2071833A1

公开(公告)日：1992-05-08

申请号：CA2071833

申请日：1991-10-30

Applicant: BAXTER INT

Inventor： PAYRAT JEAN-MARC ,  HOGMAN CLAES F ,  DEBRAUWERE JACK ,  MATHIAS JEAN M

IPC: A01N1/00 ,  A01N1/02 ,  A61K35/18 ,  C12N5/02 ,  C12N5/06

Abstract: The present invention provides an improved aqueous solution for suspending and storing red blood cells. The solution includes sodium citrate, a combination of sodium biphosphate and sodium phosphate dibasic, adenine, and mannitol. The solution is formulated at a low osmolarity and has a physiological pH of approximately 7.4. The solution simultaneously maintains stored red cells ATP and 2,3-BPG.

公开(公告)号：CA2164825C

公开(公告)日：2006-07-18

申请号：CA2164825

申请日：1995-05-09

Applicant: BAXTER INT

Inventor： JOIE MICHEL ,  DEBRAUWERE JACK ,  BERNES JEAN-CLAUDE ,  GOLDHABER RICHARD

IPC: A61J1/10 ,  A61J3/00 ,  A61J1/00 ,  A61J1/05 ,  A61J1/20 ,  A61K35/14 ,  A61M1/02 ,  B01D21/00 ,  B01D21/26

Abstract: A container (10) for housing body fluids, preferably blood in its component form, is dis- closed. The container (10) comprises a body (12) defined by flexible walls having an interior (15) for housing the body fluid. Additionally, a means (30) for allowing selective fluid flow allows the blood components to be expressed from one chamber (17) of the container (10) into another (18) to separate and separately house the blood components. The present invention also provides a method for sepa- rating blood into its components via centrifugation and individually storing blood components in sep- arate chambers (17, 18) of the container (10).

公开(公告)号：ES2172527T3

公开(公告)日：2002-10-01

申请号：ES94901241

申请日：1993-11-03

Applicant: BAXTER INT

Inventor： BERNES JEAN-CLAUDE ,  DEBRAUWERE JACK ,  JOIE MICHEL ,  VAN BREEDAM BAUDOUIN ,  MATHIAS JEAN-MARIE

IPC: A61B5/154 ,  A61B5/15 ,  A61B5/153 ,  A61B5/155 ,  A61M1/02 ,  A61M39/02 ,  A61B5/00

Abstract: A blood sampling system including a sampling device located in line is provided. The sampling device provides an access port that allows undiluted blood to be sampled automatically by insertion of a luer. The sampling device can have a number of different structures, for example, a swing valve, a ball valve, or a breakable seal for normally closing the sample port until a nozzle of the luer blood collector is forcibly inserted into the sample port.

公开(公告)号：NO313033B1

公开(公告)日：2002-08-05

申请号：NO960110

申请日：1996-01-10

Applicant: BAXTER INT

Inventor： JOIE MICHEL L F ,  DEBRAUWERE JACK ,  BERNES JEAN-CLAUDE ,  GOLDHABER RICHARD

IPC: A61J3/00 ,  A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61M1/02 ,  B01D21/00 ,  B01D21/26 ,  A61M1/00 ,  A61M37/00

公开(公告)号：DE69326147T2

公开(公告)日：2000-04-27

申请号：DE69326147

申请日：1993-10-04

Applicant: BAXTER INT

Inventor： DEBRAUWERE JACK ,  MATHIAS JEAN-MARIE ,  PATEL INDRAJIT

IPC: A61J1/10 ,  A61J1/00 ,  A61J1/05 ,  A61J3/00 ,  A61L2/00 ,  A61L2/07 ,  A61B19/00 ,  A61L2/06 ,  A61M5/32

公开(公告)号：DE69326147D1

公开(公告)日：1999-09-30

申请号：DE69326147

申请日：1993-10-04

Applicant: BAXTER INT

Inventor： DEBRAUWERE JACK ,  MATHIAS JEAN-MARIE ,  PATEL INDRAJIT

IPC: A61J1/10 ,  A61J1/00 ,  A61J1/05 ,  A61J3/00 ,  A61L2/00 ,  A61L2/07 ,  A61B19/00 ,  A61L2/06 ,  A61M5/32

公开(公告)号：CA2071833C

公开(公告)日：1998-11-03

申请号：CA2071833

申请日：1991-10-30

Applicant: BAXTER INT

Inventor： PAYRAT JEAN-MARC ,  HOGMAN CLAES F ,  DEBRAUWERE JACK ,  MATHIAS JEAN M

IPC: A01N1/00 ,  A01N1/02 ,  A61K35/18 ,  C12N5/08 ,  C12N5/06

Abstract: The present invention provides an improved aqueous solution for suspending and s toring red blood cells. The solution includes sodium citrate, a combination of sodium biphosphate and sodium phosphate dibasic , adenine, and mannitol. The solution is formulated at a low osmolarity and has a physiological pH of approximately 7. 4. The solution simultaneously maintains stored red cells ATP and 2,3-BPG.

公开(公告)号：DE69126861T2

公开(公告)日：1998-02-26

申请号：DE69126861

申请日：1991-10-30

Applicant: BAXTER INT

Inventor： PAYRAT JEAN-MARC ,  HOGMAN CLAES ,  DEBRAUWERE JACK ,  MATHIAS JEAN-MARIE

IPC: A01N1/00 ,  A01N1/02 ,  A61K35/18

Abstract: The present invention provides an improved aqueous solution for suspending and storing red blood cells. The solution includes sodium citrate, a combination of sodium biphosphate and sodium phosphate dibasic, adenine, and mannitol. The solution is formulated at a low osmolarity and has a physiological pH of approximately 7.4. The solution simultaneously maintains stored red cells ATP and 2,3-BPG.

公开(公告)号：AU2476995A

公开(公告)日：1995-12-05

申请号：AU2476995

申请日：1995-05-09

Applicant: BAXTER INT

Inventor： JOIE MICHEL ,  DEBRAUWERE JACK ,  BERNES JEAN-CLAUDE ,  GOLDHABER RICHARD

IPC: A61J3/00 ,  A61J1/00 ,  A61J1/05 ,  A61J1/10 ,  A61K35/14 ,  A61M1/02 ,  B01D21/00 ,  B01D21/26 ,  A61M37/00

公开(公告)号：CA2124936A1

公开(公告)日：1994-04-14

申请号：CA2124936

申请日：1993-10-04

Applicant: BAXTER INT

Inventor： DEBRAUWERE JACK ,  MATHIAS JEAN-MARIE ,  PATEL INDRAJIT

IPC: A61J1/10 ,  A61J1/00 ,  A61J1/05 ,  A61J3/00 ,  A61L2/00 ,  A61L2/07 ,  A61L2/06

Abstract: 2124936 9407426 PCTABS00032 A steam sterilizable unit (10) for inactivating pathogens in a body fluid is provided comprising a plastic structure for housing a therapeutically effective amount of a methylene blue solution. The plastic structure preferably includes at least an inner layer (128) constructed from a non-PVC plastic. Preferably, the methylene blue solution has a pH of less than 7.0 and preferably less than or equal to approximately 6.3.