公开(公告)号：SG48702A1

公开(公告)日：1998-05-18

申请号：SG1995002031

申请日：1994-03-17

Applicant: BAXTER INT

Inventor： SEGERS ALAIN ,  FAICT DIRK ,  DUPONCHELLE ANNICK ,  HARTMAN JEAN-PIERRE ,  PELUSO FRANCESCO

IPC: A61J1/00 ,  A61J1/14 ,  A61J1/20 ,  A61J1/05 ,  A61J3/00 ,  A61K33/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61P3/00 ,  C01B32/60

Abstract: A method and device for stabilizing and storing bicarbonate solutions is provided. In an embodiment, a device is provided having a container and carbon-dioxide generating substances that include a solid material which upon contact with water generates carbon-dioxide gas. The device may be packaged together with the bicarbonate or in a separate overpouch. The present invention also provides a method for the stabilization of bicarbonate solutions utilizing a means that generates high pressure carbon dioxide.

公开(公告)号：DE69403572T2

公开(公告)日：1998-01-02

申请号：DE69403572

申请日：1994-01-18

Applicant: BAXTER INT

Inventor： BALTEAU PATRICK ,  FAICT DIRK ,  PELUSO FRANCESCO

IPC: B65D81/32 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  B65D30/22

Abstract: A multiple chamber container for mixing and administering a plurality of products. The container has at least two chambers separated by a seal line. A frangible connector is situated between the two chambers for mixing the products contained within the chambers as desired. Each chamber has at least one port for filling of product into the chamber. The ports are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.

公开(公告)号：AU683863B2

公开(公告)日：1997-11-27

申请号：AU5848594

申请日：1993-12-10

Applicant: BAXTER INT

Inventor： MARTIS LEO ,  BURKE RON ,  FAICT DIRK

IPC: A61K9/08 ,  A61K31/70 ,  A61K33/00 ,  A61K38/00 ,  A61K38/01 ,  A61K38/02 ,  A61K47/26 ,  A61K47/42 ,  A61M1/14 ,  A61M1/28 ,  A61P7/08 ,  A61K37/02 ,  A61K37/18

Abstract: The solution contains as osmotic agents both dectrose and polypeptides. The polypeptides are synthetic and are 4 to 10 amino acids long.

公开(公告)号：ES2103123T3

公开(公告)日：1997-08-16

申请号：ES94906646

申请日：1994-01-18

Applicant: BAXTER INT

Inventor： BALTEAU PATRICK ,  FAICT DIRK ,  PELUSO FRANCESCO

IPC: B65D81/32 ,  A61J1/00 ,  A61J1/10 ,  A61J1/20 ,  A61M1/28 ,  B65D30/22

Abstract: A multiple chamber container for mixing and administering a plurality of products. The container has at least two chambers separated by a seal line. A frangible connector is situated between the two chambers for mixing the products contained within the chambers as desired. Each chamber has at least one port for filling of product into the chamber. The ports are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.

公开(公告)号：NZ263691A

公开(公告)日：1996-11-26

申请号：NZ26369194

申请日：1994-03-17

Applicant: BAXTER INT

Inventor： SEGERS ALAIN ,  FAICT DIRK ,  DUPONCHELLE ANNICK ,  HARTMAN JEAN-PIERRE ,  PELUSO FRANCESCO

IPC: A61J1/00 ,  A61J1/14 ,  A61J1/20 ,  A61J3/00 ,  A61K33/00 ,  A61M1/14 ,  A61J1/05 ,  A61M1/16 ,  A61M1/28 ,  A61P3/00 ,  C01B32/60 ,  C09K15/02

Abstract: A method and device for stabilizing and storing bicarbonate solutions is provided. In an embodiment, a device is provided having a container and carbon-dioxide generating substances that include a solid material which upon contact with water generates carbon-dioxide gas. The device may be packaged together with the bicarbonate or in a separate overpouch. The present invention also provides a method for the stabilization of bicarbonate solutions utilizing a means that generates high pressure carbon dioxide.

公开(公告)号：DE60030682T3

公开(公告)日：2018-03-29

申请号：DE60030682

申请日：2000-07-27

Applicant: BAXTER INT

Inventor： DUPONCHELLE ANNICK ,  FAICT DIRK ,  BALTEAU PATRICK ,  HARTMAN JEAN-PIERRE ,  MARTIS LEO ,  PELUSO FRANCESCO

IPC: A61J3/00 ,  A61K33/10 ,  A61J1/05 ,  A61J1/10 ,  A61J1/20 ,  A61K33/14 ,  A61M1/14 ,  A61M1/16 ,  A61M1/28 ,  A61P13/12

公开(公告)号：DE602004015485D1

公开(公告)日：2008-09-11

申请号：DE602004015485

申请日：2004-09-22

Applicant: BAXTER HEALTHCARE SA ,  BAXTER INT

Inventor： SOMERS FABIAN ,  FAICT DIRK

IPC: A61K38/05 ,  A61K38/06 ,  A61K38/18

Abstract: The present invention relates to stable pharmaceutical protein formulations that are stabilized using peptide stabilizers selected from the group consisting of Gly-Gly, Gly-Gly-Gly, Gly-Tyr, Gly-Phe, Gly-His, Gly-Asp, Gly-Ala, Ala-Gly, Ala-Ala, derivatives thereof and mixtures thereof. Furthermore, the present invention relates to stable pharmaceutical formulations comprising erythropoietin and peptide stabilizers selected from dipeptides, tripeptides, tetrapeptides, pentapeptides, and mixtures thereof. In addition to peptide stabilizers, the formulations may contain surfactants.

公开(公告)号：AT402714T

公开(公告)日：2008-08-15

申请号：AT04784802

申请日：2004-09-22

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： SOMERS FABIAN ,  FAICT DIRK

IPC: A61K38/05 ,  A61K38/06 ,  A61K38/18

Abstract: The present invention relates to stable pharmaceutical protein formulations that are stabilized using peptide stabilizers selected from the group consisting of Gly-Gly, Gly-Gly-Gly, Gly-Tyr, Gly-Phe, Gly-His, Gly-Asp, Gly-Ala, Ala-Gly, Ala-Ala, derivatives thereof and mixtures thereof. Furthermore, the present invention relates to stable pharmaceutical formulations comprising erythropoietin and peptide stabilizers selected from dipeptides, tripeptides, tetrapeptides, pentapeptides, and mixtures thereof. In addition to peptide stabilizers, the formulations may contain surfactants.

公开(公告)号：CA2399440C

公开(公告)日：2007-03-27

申请号：CA2399440

申请日：1996-08-27

Applicant: BAXTER INT

Inventor： COLLERAN LISA ,  EMERSON PAUL FREDERICK ,  FAICT DIRK ,  CHEN CHI J ,  CHILDERS ROBERT WARREN ,  PELUSO FRANCESCO ,  EERLINGEN VITAL ,  BALTEAU PATRICK

IPC: A61M1/28 ,  A61M5/14 ,  A61M5/168

Abstract: A system and a method are provided for admixing solutions. The system includes containers separately accessible by one or more pumps for mixture of the solutions in a container immediately before administration to a peritoneal cavity of a patient. Alternatively, the system and method allow for direct administration of the mixed solution to the peritoneal cavity of a patient without intermediate mixing thereof. The solutions may be mixed in predetermined ratios as input to the system prior to delivery.

公开(公告)号：MXPA06014254A

公开(公告)日：2007-03-12

申请号：MXPA06014254

申请日：2005-05-18

Applicant: BAXTER INT

Inventor： FAICT DIRK ,  DEGREVE BART ,  GERICKE MARION ,  DUPONCHELLE ANNICK

IPC: A61K33/10 ,  A61K9/50 ,  A61K33/00 ,  A61M1/28

Abstract: Se proporcionan soluciones a base de bicarbonato para dialisis y metodos para fabricar y utilizar las mismas. La solucion de dialisis incluye por lo menos tres partes de una solucion que estan almacenadas y esterilizadas en forma separada a un pH eficaz para promover la estabilizacion de las partes de solucion incluyendo la parte de solucion sensible al pH que tiene, por ejemplo, un agente osmotico sensible al pH, tal como un polimero de glucosa. Las partes de solucion se mezclan para formar una solucion lista para uso con un pH fisiologicamente aceptable.