公开(公告)号：CA3072349A1

公开(公告)日：2019-03-07

申请号：CA3072349

申请日：2018-08-30

Applicant: CYTOSORBENTS CORP

Inventor： SIMM ANDREAS VIKTOR ,  SCHEIER JORG ,  STEINER CHRISTIAN ,  CAPPONI VINCENT ,  CHAN PHILLIP P

IPC: A61B5/15 ,  C09K23/48 ,  C09K23/52 ,  G01N1/10 ,  G01N33/49

Abstract: The invention concerns removing advanced glycation end products from a bodily fluid by contacting the bodily fluid with a sorbent.

公开(公告)号：AU2017272021A1

公开(公告)日：2018-11-29

申请号：AU2017272021

申请日：2017-05-18

Applicant: CYTOSORBENTS CORP

Inventor： GULIASHVILI TAMAZ ,  GOLOBISH THOMAS ,  GRUDA MARYANN ,  O'SULLIVAN PAMELA ,  SCHEIRER ANDREW ,  CAPPONI VINCENT ,  CHAN PHILLIP ,  YOUNG WEI-TAI

IPC: B01J20/32 ,  B01D15/34 ,  B01J20/28

Abstract: The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising either polyol or zwitterionic groups designed to adsorb endotoxins and other inflammatory mediator molecules. The inventions are in the field of porous polymeric sorbents, also in the field of broadly reducing endotoxins in blood and blood products that can cause endotoxemia, additionally, in the field of broadly removing endotoxins by perfusion or hemoperfusion.

公开(公告)号：AU2016342263A1

公开(公告)日：2018-04-26

申请号：AU2016342263

申请日：2016-10-21

Applicant: CYTOSORBENTS CORP

Inventor： GOLOBISH THOMAS ,  GRUDA MARYANN ,  GULIASHVILI TAMAZ ,  O'SULLIVAN PAMELA ,  SCHEIRER ANDREW ,  DAN VI ,  YOUNG WEI-TAI ,  CAPPONI VINCENT ,  CHAN PHILLIP

IPC: A61M5/165 ,  A61K31/795 ,  A61K47/20 ,  A61M1/34

Abstract: The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium.