公开(公告)号：CA2795177C

公开(公告)日：2018-07-03

申请号：CA2795177

申请日：2011-04-01

Applicant: CYTOSORBENTS CORP

Inventor： CHAN PHILLIP P ,  YOUNG WEI-TAI ,  CAPPONI VINCENT J ,  GOLOBISH THOMAS D ,  BARTLETT ROBERT H ,  ALI HUMAYRA BEGUM

IPC: A61K31/74 ,  A61K31/717 ,  A61P29/00

Abstract: The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.

公开(公告)号：AU2016342263A1

公开(公告)日：2018-04-26

申请号：AU2016342263

申请日：2016-10-21

Applicant: CYTOSORBENTS CORP

Inventor： GOLOBISH THOMAS ,  GRUDA MARYANN ,  GULIASHVILI TAMAZ ,  O'SULLIVAN PAMELA ,  SCHEIRER ANDREW ,  DAN VI ,  YOUNG WEI-TAI ,  CAPPONI VINCENT ,  CHAN PHILLIP

IPC: A61M5/165 ,  A61K31/795 ,  A61K47/20 ,  A61M1/34

Abstract: The invention concerns biocompatible polymer systems comprising at least one polymer with a plurality of pores, said polymer comprising a sulfonic acid salt functionality designed to adsorb a broad range of protein based toxins from less than 0.5 kDa to 1,000 kDa and positively charged ions including but not limited to potassium.

公开(公告)号：CA2963458A1

公开(公告)日：2016-04-07

申请号：CA2963458

申请日：2015-10-02

Applicant: CYTOSORBENTS CORP

Inventor： ALI HUMAYRA BEGUM ,  GOLOBISH THOMAS D ,  CAPPONI VINCENT J ,  CHAN PHILLIP P ,  YOUNG WEI-TAI ,  SCHEIRER ANDREW ROBERT

IPC: A61K31/74 ,  A61K31/745 ,  A61K31/75 ,  C08F236/20

Abstract: Disclosed herein are compositions and methods for preventing or treating acute or chronic oral mucositis, esophagitis, enteritis, colitis, or gastrointestinal acute radiation syndrome (GI-ARS) caused by radiation exposure, using one or more enteron sorbent polymers administered gastrointestinally (e.g. orally, via feeding or gastric tube, via ostomy, or rectally).

公开(公告)号：AU2011234978A1

公开(公告)日：2012-10-18

申请号：AU2011234978

申请日：2011-04-01

Applicant: CYTOSORBENTS CORP

Inventor： CHAN PHILLIP P ,  YOUNG WEI-TAI ,  CAPPONI VINCENT J ,  GOLOBISH THOMAS D ,  BARLETT ROBERT H

IPC: A61K31/74

Abstract: The present invention concerns methods of treating systemic, regional, or local inflammation from a patient suffering or at risk of inflammation comprising administration of a therapeutically effective dose of a sorbent that sorbs an inflammatory mediator in said patient. In some preferred embodiments, the sorbent is a biocompatible organic polymer.