公开(公告)号：AT89862T

公开(公告)日：1993-06-15

申请号：AT88106748

申请日：1988-04-27

Applicant: HOECHST AG ,  MAX PLANCK GESELLSCHAFT

Inventor： BROCKS DIETRICH DR ,  PUENTER JUERGEN DR ,  STRECKER HELMUT DR ,  TIMPL RUPERT DR

IPC: G01N33/53 ,  C07K14/005 ,  C07K14/195 ,  C07K16/00 ,  C07K16/18 ,  C12N5/10 ,  C12N5/12 ,  C12N15/02 ,  C12P21/00 ,  C12P21/08 ,  C12R1/91 ,  G01N33/577 ,  G01N33/68 ,  C07K15/00

公开(公告)号：AT55489T

公开(公告)日：1990-08-15

申请号：AT83102338

申请日：1983-03-10

Applicant: HOECHST AG

Inventor： TIMPL RUPERT DR ,  BROCKS DIETRICH DR ,  NEUBAUER HORST DR ,  STRECKER HELMUT DR

IPC: G01N33/53 ,  A61K38/17 ,  A61K39/00 ,  A61K39/395 ,  G01N33/531 ,  G01N33/537 ,  G01N33/543 ,  G01N33/68

公开(公告)号：DE3026665A1

公开(公告)日：1982-02-11

申请号：DE3026665

申请日：1980-07-14

Applicant: HOECHST AG

Inventor： HACHMANN HENNING DR ,  STRECKER HELMUT DR ,  SEIDEL LOTHAR DR

IPC: G01N33/539 ,  G01N33/541 ,  G01N33/56

公开(公告)号：DE2712635A1

公开(公告)日：1978-09-28

申请号：DE2712635

申请日：1977-03-23

Applicant: HOECHST AG

Inventor： STRECKER HELMUT DR

IPC: G21G4/08 ,  A61N5/10 ,  G21G1/04 ,  G21H5/02

Abstract: Nuclide generators for preparing sterile and pyrogen-free radioactive solutions consist of a generator column which is provided with radiation shielding and connected to a container for eluting agent and has a connection to a container for eluate. The generator and the container for eluting agent are located in vessels with centering devices, wherein the generator column with its radiation shielding is located in a fixed position relative to the vessel between two centering devices and connected via a cannula to the container for eluting agent which is held in a recess of one centering device in a fixed position relative to the generator column. The other centering device has also a recess for guiding and holding the eluate container which is connected to the generator column via a cannula.

公开(公告)号：GR3019470T3

公开(公告)日：1996-06-30

申请号：GR960400849

申请日：1996-03-29

Applicant: HOECHST AG

Inventor： MOLZ PETER DR ,  SKRZIPCZYK HEINZ-JUERGEN DR ,  LUEBBERS HENNING DR ,  STRECKER HELMUT DR ,  SCHNORR GERD DR ,  KINKEL TONIO DR

IPC: C07D219/04 ,  C07D401/12 ,  C09K11/06 ,  G01N33/532 ,  G01N33/533 ,  G01N33/543 ,  G01N33/58 ,  G01N33/68

公开(公告)号：ES2066756T3

公开(公告)日：1995-03-16

申请号：ES87112127

申请日：1987-08-21

Applicant: HOECHST AG

Inventor： WISSMANN HANS DR ,  SIMONS GUIDO DR ,  STRECKER HELMUT DR

IPC: C08G65/08 ,  C07C67/00 ,  C07C239/00 ,  C07C269/04 ,  C07C271/22 ,  C08G65/02 ,  C08G65/28 ,  C08G65/32 ,  C08G65/333 ,  C08G65/48 ,  G01N33/53 ,  G01N33/78

公开(公告)号：DE3881275D1

公开(公告)日：1993-07-01

申请号：DE3881275

申请日：1988-04-27

Applicant: MAX PLANCK GESELLSCHAFT ,  HOECHST AG

Inventor： BROCKS DIETRICH DR ,  PUENTER JUERGEN DR ,  STRECKER HELMUT DR ,  TIMPL RUPERT DR

IPC: G01N33/53 ,  C07K14/005 ,  C07K14/195 ,  C07K16/00 ,  C07K16/18 ,  C12N5/10 ,  C12N5/12 ,  C12N15/02 ,  C12P21/00 ,  C12P21/08 ,  C12R1/91 ,  G01N33/577 ,  G01N33/68 ,  C07K15/00

Abstract: New monoclonal antibody reacts strongly with intact type-III procollagen and pN collagen and with intact type-III amino-terminal procollagen peptide (atPP) but not significantly with Col 1 or with ATPP degradation prods. having the same molecular wt. as Col 1. Specifically antibody is PIIIP 296 and is produced by the hybridoma cell line ECACC 87042308. This cell line is produced by immunising SJL mice with purified ATPP and fusing the mouse spleen cells with P3X63AG8.653 myeloma cells.

公开(公告)号：DE3770743D1

公开(公告)日：1991-07-18

申请号：DE3770743

申请日：1987-09-29

Applicant: HOECHST AG

Inventor： SCHNORR GERD DR ,  STRECKER HELMUT DR ,  MOLZ PETER DR ,  SIMONS GUIDO DR ,  SKRZIPCZYK HEINZ JUERGEN DR

IPC: G01N33/541 ,  G01N33/543 ,  G01N33/574 ,  G01N33/577 ,  G01N33/76 ,  G01N33/78

公开(公告)号：AT64467T

公开(公告)日：1991-06-15

申请号：AT87114166

申请日：1987-09-29

Applicant: HOECHST AG

Inventor： SCHNORR GERD DR ,  STRECKER HELMUT DR ,  MOLZ PETER DR ,  SIMONS GUIDO DR ,  SKRZIPCZYK HEINZ JUERGEN DR

IPC: G01N33/541 ,  G01N33/543 ,  G01N33/574 ,  G01N33/577 ,  G01N33/76 ,  G01N33/78

公开(公告)号：DE3381781D1

公开(公告)日：1990-09-13

申请号：DE3381781

申请日：1983-03-10

Applicant: HOECHST AG

Inventor： TIMPL RUPERT DR ,  BROCKS DIETRICH DR ,  NEUBAUER HORST DR ,  STRECKER HELMUT DR

IPC: G01N33/53 ,  A61K38/17 ,  A61K39/00 ,  A61K39/395 ,  G01N33/531 ,  G01N33/537 ,  G01N33/543 ,  G01N33/68

Abstract: The antigens procollagen peptide (type (III) and procollagen peptide col 1 (type III) can be determined together immunologically by either (a) reacting a specified amount in each case of labeled procollagen peptide (type III) or procollagen peptide col 1 (type III) and a highly specific antiserum containing antibodies having affinity for both the antigens mentioned together with a sample having an unknown content of procollagen peptide (type III) and/or procollagen peptide col 1 (type III), separating off the antigen-antibody complex formed and measuring the amount of labeling in the complex and/or in the supernatant, or (b) bringing a specified amount of the highly specific antiserum to reaction with a sample having an unknown content of procollagen peptide (type III) and/or procollagen peptide col 1 (type III), fixing the unreacted amount of the antibody to procollagen peptide (type III) or procollagen peptide col 1 (type III) bound to a support, and bringing to reaction with a labeled second antibody, and then determining the amount of bound or excess second antibody by measuring the labeling. An anti-procollagen peptide col 1 (type III) serum is preferred as the highly specific serum, and this is obtained by using procollagen peptide col 1 (type III) for immunizing experimental animals and obtaining their serum.