中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

17 records (took 0.019 seconds)

    Chemiluminescent 9-sulphonyl-aminocarbonyl-acridinium salts
    8.
    发明专利
    Chemiluminescent 9-sulphonyl-aminocarbonyl-acridinium salts 未知

    公开(公告)号：DE3805318A1

    公开(公告)日：1989-08-31

    申请号：DE3805318

    申请日：1988-02-20

    Applicant: HOECHST AG

    Inventor： KINKEL TONIO DR ,  MOLZ PETER DR ,  SCHMIDT ERWIN DR ,  SCHNORR GERD DR ,  SKRZIPCZYK HEINZ JUERGEN DR

    IPC: C09B15/00 ,  G01N33/533 ,  G01N33/58

    Abstract: Chemiluminescent acridinium derivs. of formula (I) and their quat. ammonium derivs. are new: R1 = H; up to 10C alkyl, alkenyl or alkynyl; benzyl or aryl; R2 and R3 = H, 1-4C alkyl, amino (opt.substd.), COOH, alkoxy, CN, NO2 or halo; R4 = -N(R6)-SO2-XR5 or -N(XR5)-SO2R6; R5 = reactive gp. which, under mild conditions, can form a bond selectively with an NH2, COOH, SH or other functional gp.in a biologically interesting cpd.; R6 = H; up to 10C alkyl, alkenyl or alkoxy; substd. amino; benzyl; aryl; heteroalkyl or heterocyclyl, opt. substd. by OH; amino; alkylamino; 1-4C alkyl, alkenyl or alkoxy; polyalkoxy, aryloxy or heterocyclyl, one or more times, and these substits. may themselves be substd. by heterocyclyl or amino, or together form a heterocycle contg. at least one O, S, NH or N-alkyl; X = arylene bonded to N or S directly or via an alkylene or oxyalkylene gp., and bonded via alkylene or oxyalkylene to R5, and opt. substd. by 1 or more alkyl, alkenyl, OH, NH2, alkoxy or aryloxy gps. and/or heteroatoms; or X = residue of an aliphatic, araliphatic or aromatic aminoacid (not necessarily natural); if R6 = phenyl substd. by 1 or more 1-6C alkyl, then X can also be phenylene. A- is not defined but is an anion in all examples

    New chemiluminescent 9-carboxy-acridinium cpds.
    10.
    发明专利
    New chemiluminescent 9-carboxy-acridinium cpds. 未知

    公开(公告)号：DE3645292C2

    公开(公告)日：1997-12-11

    申请号：DE3645292

    申请日：1986-08-22

    Applicant: HOECHST AG

    Inventor： MOLZ PETER DR ,  SKRZIPCZYK HEINZ JUERGEN DR ,  LUEBBERS HENNING DR ,  STRECKER HELMUT DR ,  SCHNORR GERD DR ,  KINKEL TONIO DR

    IPC: C07D219/04 ,  C07D401/12 ,  C09K11/06 ,  G01N33/532 ,  G01N33/533 ,  G01N33/543 ,  G01N33/58 ,  G01N33/68 ,  C09K11/07

    Abstract: (A) Chemiluminescent 9-carboxy-acridinium derivs. of formula (I) are new, where R1 = H, 1-10C alkyl, alkenyl or alkynyl, benzyl or aryl; R2, R3 = H, 1-4C alkyl, opt. substd. amino, COOH, alkoxy, CN, NO2 or halogen; R4 = residue in which a sulphonamide group is linked via the N-atom with the carbonyl group, or a thio residue of the formula -S-X-R5; X = opt. branched aliphatic or azomatic group, opt. contg. a hetero atom; R5 = reactive group capable of reacting under mild conditions selectively with amino, carboxy, thiol or other functional groups in substances of biological interest; A = anion not adversely affecting the chemiluminescence. (B) Luminescent cpds. in which a cpd. (I) is bound directly or via a bridging molecule to a protein, polypeptide or other biologically interesting substance to form a stable, immunologically active complex are new and claimed. (C) Luminescence immunoassays for the determination of an antigenic substance in a liquid specimen in which at least one immunologically active component is immoblised on a solid phase in a competitive or sandwich process and in which the tracer is a luminescent cpd. as defined under (B) are new.

Patent Agency Ranking