公开(公告)号：ZA782629B

公开(公告)日：1979-04-25

申请号：ZA782629

申请日：1978-05-09

Applicant: HOECHST AG

Inventor： WEYER R ,  HITZEL V ,  GEISEN K ,  PFAFF W

IPC: C07D213/81 ,  A61K31/63 ,  A61P3/08 ,  A61P3/10 ,  C07D213/82 ,  A61K31/455

公开(公告)号：NZ185078A

公开(公告)日：1979-03-28

申请号：NZ18507877

申请日：1977-09-02

Applicant: HOECHST AG

Inventor： WEYER R ,  HITZEL V ,  GRANZER E

IPC: A61K31/195 ,  A61K31/38 ,  A61K31/381 ,  A61P3/06 ,  C07C229/38 ,  C07C233/81 ,  C07C235/52 ,  C07D333/38

Abstract: Benzoic acids of the general formula I I in which R, R1, R2 and Y have the meanings as mentioned in the following, and which in the form of the free compounds or in the form of the physiologically tolerated salts and esters possess valuable pharmacological properties, processes for preparing them, pharmaceutical preparations containing them, and their use as or in medicaments.

公开(公告)号：DK71278A

公开(公告)日：1978-08-19

申请号：DK71278

申请日：1978-02-17

Applicant: HOECHST AG

Inventor： HITZEL V ,  WEYER R ,  GEISEN K ,  PFAFF W

IPC: C07D213/81 ,  C07D213/80 ,  C07D213/82 ,  C07D

Abstract: Benzoic acid derivatives of the formula wherein T is hydrogen or halogen, W is a carboxyl group, an ester or salt thereof; X is wherein R1 is alkyl having from 2 to 8 carbon atoms, aralkyl or phenyl, cycloalkyl, cycloalkylalkyl or alkylcycloalkyl; R2 is hydrogen or halogen, R3 is alkyl having from 5 to 8 carbon atoms, aralkyl or phenyl, or cycloalkyl having from 5 to 8 carbon atoms; R4 is hydrogen or alkyl; Y is a single chemical bond or a hydrocarbon chain having from 1 to 3 carbon atoms; and Z is hydrogen, halogen, alkyl, alkoxy, alkoxyalkoxy or alkenyloxy, have a blood sugar lowering effect and can be used for the treatment of Diabetes mellitus.

公开(公告)号：SE7801885L

公开(公告)日：1978-08-18

申请号：SE7801885

申请日：1978-02-17

Applicant: HOECHST AG

Inventor： HITZEL V ,  WEYER R ,  GEISEN K ,  PFAFF W

IPC: C07D213/80 ,  C07D213/81 ,  C07D213/82

Abstract: Benzoic acid derivatives of the formula wherein T is hydrogen or halogen, W is a carboxyl group, an ester or salt thereof; X is wherein R1 is alkyl having from 2 to 8 carbon atoms, aralkyl or phenyl, cycloalkyl, cycloalkylalkyl or alkylcycloalkyl; R2 is hydrogen or halogen, R3 is alkyl having from 5 to 8 carbon atoms, aralkyl or phenyl, or cycloalkyl having from 5 to 8 carbon atoms; R4 is hydrogen or alkyl; Y is a single chemical bond or a hydrocarbon chain having from 1 to 3 carbon atoms; and Z is hydrogen, halogen, alkyl, alkoxy, alkoxyalkoxy or alkenyloxy, have a blood sugar lowering effect and can be used for the treatment of Diabetes mellitus.

公开(公告)号：ZA7705333B

公开(公告)日：1978-07-26

申请号：ZA7705333

申请日：1977-09-02

Applicant: HOECHST AG

Inventor： WEYER R ,  HITZEL V ,  GRANZER E

IPC: A61K31/195 ,  A61K31/38 ,  A61K31/381 ,  A61P3/06 ,  C07C229/38 ,  C07C233/81 ,  C07C235/52 ,  C07D333/38 ,  C07C ,  A61K

CPC classification number: C07C229/38 ,  C07D333/38

公开(公告)号：ZA7705045B

公开(公告)日：1978-07-26

申请号：ZA7705045

申请日：1977-08-19

Applicant: HOECHST AG

Inventor： HITZEL V ,  GRANZER E ,  WEYER R

IPC: C07D213/80 ,  C07D213/85 ,  C07D

CPC classification number: C07D213/80 ,  C07C255/00 ,  C07D213/85

公开(公告)号：ZA772950B

公开(公告)日：1978-04-26

申请号：ZA772950

申请日：1977-05-17

Applicant: HOECHST AG

Inventor： HITZEL V ,  PFAFF W ,  WEYER R ,  GEISEN K

IPC: A61K31/44 ,  A61K31/4412 ,  A61K31/4418 ,  A61K31/4425 ,  A61K31/47 ,  A61P25/04 ,  C07D213/82 ,  C07D215/54 ,  C07D ,  A61K

公开(公告)号：DK214577A

公开(公告)日：1977-11-19

申请号：DK214577

申请日：1977-05-17

Applicant: HOECHST AG

Inventor： HITZEL V ,  WEYER R ,  PFAFF W ,  GEISEN K

IPC: A61K31/44 ,  A61K31/4412 ,  A61K31/4418 ,  A61K31/4425 ,  A61K31/47 ,  A61P25/04 ,  C07D213/82 ,  C07D215/54 ,  C07D

公开(公告)号：DK124477C

公开(公告)日：1977-08-01

申请号：DK90870

申请日：1970-02-24

Applicant: HOECHST AG

Inventor： WEBER H ,  AUMUELLER W ,  MUTH K ,  WEYER R

IPC: A61K31/64 ,  A61K31/17 ,  C07C67/00 ,  C07C301/00 ,  C07C303/36 ,  C07C303/40 ,  C07C311/58 ,  C07C311/59 ,  C07D233/96 ,  C07C143/833

公开(公告)号：ZA7600007B

公开(公告)日：1976-12-29

申请号：ZA7600007

申请日：1976-01-02

Applicant: HOECHST AG

Inventor： PFAFF W ,  HITZEL V ,  GEISEN K ,  WEYER R

IPC: C07C67/00 ,  C07C231/00 ,  C07C231/02 ,  C07C231/10 ,  C07C231/12 ,  C07C233/81 ,  C07C235/52 ,  C07C237/36 ,  C07D213/82 ,  C07D215/44 ,  C07D215/48 ,  C07D307/79 ,  C07D311/58 ,  C07D333/38 ,  C07D ,  A61K

CPC classification number: C07D213/82 ,  C07D215/48 ,  C07D307/79 ,  C07D311/58 ,  C07D333/38 ,  Y10S514/866