公开(公告)号：EP0358250A2

公开(公告)日：1990-03-14

申请号：EP89201949.8

申请日：1989-07-25

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Calzi, Claudio

IPC: G01N27/416

CPC classification number: G01N27/4163 ,  Y10T436/102499

Abstract: A pre-determined amount of solubilized reagent is reacted to release CO₂ in a controlled-temperature reaction vessel and a controlled-pressure area adjacent the reaction vessel.
The devices that enable the system to be maintained in the liquid phase, and the reaction vessel itself, are controlled, assuming that the O₂ in the solution is such as that deriving from the presence of O₂ in the atmosphere, if necessary corrected for the effect of the reaction producing CO₂.
Thus, the amount of reagent taking part in the reaction being known, either by assay or by controlling the reaction time, by controlling the amount of O₂ in the solution containing the reagent, the barometric pressure, the temperature in the reaction vessel, and the coefficients of solubility of the two gases, it becomes possible to predict the partial pressures of O₂ and CO₂ in the liquid phase produced, which liquid phase is suitable for use as a calibration substance for an apparatus for measuring blood gases.

Abstract translation: 增溶的试剂的预确定的量进行反应在受控温度下的反应容器和一个受控压力区域相邻的反应容器，以释放CO 2。 设备确实使被保持在液相中的系统中，并且将反应容器本身被控制，假设没有象从O2的在大气中的存在推导O2在溶液中进行检查，如果需要校正的效果 的反应生产CO 2。 因此，试剂的参与反应的量是已知的，或者通过测定或通过控制反应时间，通过控制在溶液中的O 2的量的含有试剂，气压，在反应容器中的温度，并且 两种气体的溶解度系数，能够预测O2和CO2的分压在所产生的液体相，其液相是适合用作在设备中的校准物质用于测量血液气体。

公开(公告)号：EP0354604A2

公开(公告)日：1990-02-14

申请号：EP89201744.3

申请日：1989-06-29

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Calzi, Claudio ,  Premoli, Pietro

IPC: G01N27/416

CPC classification number: G01N27/4162

Abstract: A system is disclosed for measuring the partial pressure of a gas, and in particular of carbon dioxide (p CO ). The system uses an electrolytic solution of weak ionic strenght which is circulated between an ion-selective electrode and a membrane permeable to gases but not to the ions and substantially distant from the electrode. The partial pressure of the gas is measured after a fraction of the electrolytic solution has been permeated by the gas present in the sample and subsequently has been transferred on the sensible portion of the electrode.

Abstract translation: 一种系统是游离缺失盘用于测量气体的分压，和在二氧化碳（CO P）的具体。 该系统使用弱离子实力的电解液的所有其在离子选择性电极和膜透过气体但不与离子和从电极基本上遥远之间循环的。 后的电解液的一小部分已经通过样品中存在的气体透过，并随后已经转移上的电极的敏感部分的气体的局部压力被测量。

公开(公告)号：EP0185405A1

公开(公告)日：1986-06-25

申请号：EP85201844.9

申请日：1985-11-12

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Bonfiglio, Paolo ,  Calzi, Claudio

IPC: G01N21/25

CPC classification number: G01N21/255 ,  G01J1/1626 ,  G01N21/07 ,  G01N21/314 ,  G01N2201/0696 ,  G01N2201/08

Abstract: In an analytical photometer, in particular multi-channel,for the simultaneous analysis of a multiplicity of samples, the light source provided is a flash tube for producing light pulses in which a permanent preionization discharge is maintained and the light energy is derived by optical fibres to be sent to optical systems where the beam is divided into an analysis beam which travels through the sample and a reference beam, both finally delivered to photodetectors. Both the divided beams pass through identical filtering systems for selection of a narrow spectral band of relevance for analytical purposes.

公开(公告)号：EP0123178A3

公开(公告)日：1985-08-14

申请号：EP84103733

申请日：1984-04-04

Applicant: INSTRUMENTATION LABORATORY S.p.A.

Inventor： Calzi, Claudio

IPC: G01N21/07 ,  B04B05/04

CPC classification number: G01N21/07

Abstract: Analytical photometer for the practically simultaneous determination of the presence of different substances in a certain number of discrete samples. The photometer (10) is equipped with a centrifugal type rotor (16), already known in the art, containing a large number of chambers with inlet holes (20, 22) for the sample/samples and reagents and with axially aligned transparent windows, thereby forming a system of rotating cuvettes (18). The rotor compartments (16) serve as receptacles for the solutions and are designed and dimensioned as already known in the art, such as to retain the liquid when said rotor (16) is at rest and to transfer said liquid into the cuvettes (18) when the rotor (16) rotates. A single or multiple light source (L) is provided, which is transmitted in a novel manner through a system of suitable means, in particular, optical fibres (30-35) to various photodetector units (60 to 65), suitably aligned with the transparent windows of the cuvettes (18) by means of the same number of interference filters (50to 55) and appropriate holes (40 to 45) situated in the base (15) of the rotor (16). Thus it is possible to determine for the first time, concentrations of chemical solutions through the absorbance in the sample/samples plus reagent/reagents contained in the cuvettes (18) at various wave lengths, with wave energy being delivered from source (L). Hence it is possible to examine more than one cuvette (18) almost simultaneously and singly, each one for a different analytical parameter, and consequently to examine the transmittance and/or absorbance of the samples contained in the cuvettes at optimum wave length.