公开(公告)号：AT154754T

公开(公告)日：1997-07-15

申请号：AT92909927

申请日：1992-03-23

Applicant: ISP INVESTMENTS INC

Inventor： BISS RUSSEL B ,  COHEN JEFFREY M ,  MERIANOS JOHN J ,  TAYLOR PAUL D

IPC: C08J3/12 ,  A01N59/00 ,  A61K8/22 ,  A61K8/81 ,  A61K31/79 ,  A61K33/40 ,  A61Q17/00 ,  A61Q19/00 ,  C01B15/01 ,  C08J9/28 ,  C08K3/16 ,  C08K3/18 ,  C08L39/00 ,  C08L39/06 ,  C08L101/00 ,  C11D3/39 ,  A61K7/40 ,  C01B15/037

公开(公告)号：AU5142693A

公开(公告)日：1994-05-24

申请号：AU5142693

申请日：1993-09-29

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J

IPC: C07C217/08 ,  C08G73/02 ,  A61K31/14 ,  C07C211/63

Abstract: What is provided herein are active antimicrobial polymeric quaternary ammonium compounds which are capped with defined C12/C14 alkyl groups optionally coprecipitated with polyvinylpyrrolidone (PVP). The compounds of the invention have the formula: +TR C14alkyl (n + 2)Cl- where n is at least 2, e.g. 2-30, and C12/C14 alkyl preferably is 50:50 wt. % of dodecyl/tetradecyl alkyl.

公开(公告)号：AU4113993A

公开(公告)日：1993-11-29

申请号：AU4113993

申请日：1993-04-23

Applicant: ISP INVESTMENTS INC

Inventor： SHIH JENN S ,  MERIANOS JOHN J ,  SMITH TERRY E ,  CHUANG JUI-CHANG ,  HALDAR RAMA K

IPC: A01N59/00 ,  A01N59/12 ,  A61K9/22 ,  C08F8/00 ,  A61K31/79

公开(公告)号：AU3720793A

公开(公告)日：1993-11-08

申请号：AU3720793

申请日：1993-02-18

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J ,  GARELICK PAUL ,  LIEBERMAN HERBERT A

IPC: A61K8/19 ,  A61K8/81 ,  A61Q11/00 ,  A61K7/16

Abstract: A toothpaste composition is provided which includes the strontium salt of maleic anhydride-methyl vinyl ether copolymer. This ingredient is capable of desensitizing the nerve endings of a tooth in saliva or water because of an extension of the contact time of the strontium on the tooth surface.

公开(公告)号：CA2120335A1

公开(公告)日：1993-04-15

申请号：CA2120335

申请日：1992-08-12

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J

IPC: A01N33/12 ,  C07C211/63 ,  C07C217/08 ,  C07C233/38 ,  C08K5/19 ,  A01N25/08

Abstract: 2120335 9307251 PCTABS00021 An antimicrobial, low toxicity, non-irritating composition comprises a blend of several bis-quaternary ammonium compounds optionally coprecipitated (1) with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer, or (2) polyvinylpyrrolidone.

公开(公告)号：AU5957590A

公开(公告)日：1991-01-17

申请号：AU5957590

申请日：1990-06-18

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J ,  GARELICK PAUL

IPC: A61K31/40 ,  A61K31/4015 ,  A61K31/785 ,  A61P31/00 ,  A61P31/04 ,  C07D207/26 ,  C07D207/27 ,  C08G73/00 ,  C07D207/00 ,  C07C279/00

Abstract: Antimicrobial polymeric bisbiguanides capped with alkylene pyrrolidonyl groups having the formula: +TR where X is C2-C4 alkylene; Y is a bivalent bridging group; and n is at least 2; and acid addition salts thereof.

公开(公告)号：EP1282593A4

公开(公告)日：2005-01-19

申请号：EP01924982

申请日：2001-04-12

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J

IPC: A01N37/44 ,  A01N37/50 ,  C07C229/22 ,  C07C229/00

CPC classification number: C07C229/22 ,  A01N37/44 ,  A01N37/50

Abstract: A high purity, water-white, clear, light stable, non-toxic, formaldehyde-free composition for inhibiting growth in a substance requiring microbial inhibition comprising about 40-60 % by weight of an aqueous solution of hydroxymethylaminoacetate in the form of its alkali metal salt which is formed by the reaction of a salt of glycine, with formaldehyde, in an aqueous medium, at a pH of about 10.5-12.5, characterized by carrying out the reaction at a molar ratio of glycine to formaldehyde sufficient to maintain a molar excess of glycine in the medium and to leave a predetermined amount of residual glycine present in the composition at the conclusion of the reaction, and to preclude the presence of any detectable free formaldehyde as methylene diol in said composition.

公开(公告)号：EP0607162A4

公开(公告)日：1994-11-17

申请号：EP92917984

申请日：1992-08-12

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J

IPC: A01N33/12 ,  C07C211/63 ,  C07C217/08 ,  C07C233/38 ,  C08K5/19 ,  C11D3/48 ,  A01N25/08 ,  A61K9/14 ,  A61K31/74 ,  C07C211/00

CPC classification number: C07C233/38 ,  A01N33/12 ,  C07C211/63 ,  C07C217/08 ,  C08K5/19 ,  A01N25/10 ,  A01N2300/00 ,  C08L39/06

Abstract: An antimicrobial, low toxicity, non-irritating composition comprises a blend of several bis-quaternary ammonium compounds optionally coprecipitated (1) with a copolymer of vinylpyrrolidone and an acrylamido or vinyl quaternary ammonium monomer, or (2) polyvinylpyrrolidone.

公开(公告)号：EP1734922A4

公开(公告)日：2008-05-14

申请号：EP05728244

申请日：2005-03-11

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J ,  GARELICK PAUL ,  LINDSTROM SUSAN M

IPC: A61K9/00 ,  A01N25/34 ,  A61K8/34 ,  A61K8/44 ,  A61K31/075 ,  A61K31/325 ,  A61K31/425 ,  A61L9/01 ,  A61Q17/00

CPC classification number: A61K31/075 ,  A61K8/34 ,  A61K8/345 ,  A61K8/44 ,  A61K31/325 ,  A61K31/425 ,  A61Q17/005 ,  A61K2300/00

Abstract: What is described herein are antimicrobial compositions which are defined blends of a 1,2-diol and phenoxyethanol which show broad activity against bacteria, fungi and mold spores. This activity is potentiated by the addition thereto of small amounts of a co-biocide for which the blend acts as a delivery system for the otherwise water-insoluble co-biocide.

Abstract translation: 本文描述的是抗微生物组合物，其定义为对细菌，真菌和霉菌孢子显示广泛活性的1,2-二醇和对苯二甲醇的混合物。 通过向其中加入少量的共 - 杀生物剂来增强这种活性，其中该共混物用作其他不溶于水的共杀生物剂的递送系统。

公开(公告)号：EP0583413A4

公开(公告)日：1994-05-18

申请号：EP92913520

申请日：1992-04-01

Applicant: ISP INVESTMENTS INC

Inventor： MERIANOS JOHN J ,  LOGIN ROBERT B ,  GARELICK PAUL

IPC: A61K8/00 ,  A01N59/00 ,  A61K8/22 ,  A61K8/31 ,  A61K8/34 ,  A61K8/37 ,  A61K8/39 ,  A61K8/49 ,  A61K8/81 ,  A61K8/86 ,  A61K8/89 ,  A61K8/891 ,  A61K33/40 ,  A61K47/30 ,  A61P17/00 ,  A61Q11/00 ,  A61K7/20

CPC classification number: A61Q11/00 ,  A01N59/00 ,  A61K8/22 ,  A61K8/8176 ,  A01N25/24 ,  A01N25/22 ,  A01N25/10 ,  A01N25/02 ,  A01N2300/00

Abstract: What is provided herein is a stabilized, aqueous, film-forming, antimicrobial composition of hydrogen peroxide. The active, oxygen-generating hydrogen peroxide component in the composition is stabilized in an aqueous-polyol solvent system of predetermined polarity containing PVP. In contrast, similar formulations without PVP experienced a loss of peroxide activity upon standing. Suitably, the composition herein includes about 1-20% by weight hydrogen peroxide, about 0.1-50% by weight PVP, and about 0.1-80% by weight of a polyol, the rest being water. Preferably, about 5-20% by weight of water is present in the composition. Additional solvents may be included therein, such as alcohols, ether oxides, esters, triglycerides of fatty acids, hydrocarbons, N-vinyl lactams, silicone oils, and polyether oligomers.