公开(公告)号：JP2010200767A

公开(公告)日：2010-09-16

申请号：JP2010129792

申请日：2010-06-07

Applicant: Kao Corp ,  花王株式会社

Inventor： TAKIGAWA HIROBUMI ,  SASAJIMA MICHIYO ,  ITO NORIKO

IPC: C12N1/20 ,  A61K8/99 ,  A61Q7/00 ,  C12R1/01

Abstract: PROBLEM TO BE SOLVED: To provide a hair fostering agent promoting hair growing and hair fostering and effective for various alopecia, regardless of disease condition and constitution.
SOLUTION: There is provided a microorganism deposited with National Institute of Advanced Industrial Science and Technology Patent Microorganisms Depositary as FERM P-20586.
COPYRIGHT: (C)2010,JPO&INPIT

Abstract translation: 要解决的问题：提供促进头发生长和发育的发育剂，并且对于各种脱发有效，不论疾病状况和结构如何。

解决方案：提供了一种保藏在FERM P-20586的国家先进工业科技专利微生物保藏研究所的微生物。 版权所有（C）2010，JPO＆INPIT

公开(公告)号：JP2003176208A

公开(公告)日：2003-06-24

申请号：JP2002372317

申请日：2002-12-24

Applicant: KAO CORP

Inventor： FUJIMURA TSUTOMU ,  TSUKAHARA KAZUE ,  ITO NORIKO ,  TAKEMA YOSHINORI

IPC: A61K8/96 ,  A61K8/00 ,  A61K8/97 ,  A61K36/00 ,  A61K36/02 ,  A61K36/07 ,  A61P17/16 ,  A61P43/00 ,  A61Q19/00 ,  A61K7/00 ,  A61K7/48 ,  A61K35/78 ,  A61K35/80 ,  A61K35/84

Abstract: PROBLEM TO BE SOLVED: To obtain a collagen gel shrinkage promoter having excellent percutaneous absorption, stability, safety and price, a composition for ameliorating flabbiness of the skin and a composition for tightening the skin. SOLUTION: This collagen gel shrinkage promoter comprises one or more kinds of plants selected from ginkgo, Ipomoea coccinea L., Fucales fucus, Matricaria chamomilla, Perilla frutescens crispa, Persica semen, Panax ginseng, Foeniculum vulgare, Morus alba, Gentiant lutea, Arctium lappa, Cortinellus shiitake, Allium sativum, Humulus lupulus, Paeonia suffruticosa, Lactuca sativa, Pachyma hoelen, Rosmarinus officiealis, Astragalus sinicus, Actinidia chinensis, Salvia officinalis and Filipendula multijuga or its extract as active ingredient. COPYRIGHT: (C)2003,JPO

公开(公告)号：JP2001261538A

公开(公告)日：2001-09-26

申请号：JP2000080573

申请日：2000-03-22

Applicant: KAO CORP

Inventor： NOMURA TOMOKO ,  HOTTA MITSUYUKI ,  ITO NORIKO ,  ISHIKAWA JUNKO ,  FUJIMORI TAKETOSHI

IPC: A45D26/00 ,  A61K8/00 ,  A61K8/33 ,  A61K8/35 ,  A61K8/41 ,  A61K8/97 ,  A61K8/98 ,  A61Q9/04 ,  A61K7/155

Abstract: PROBLEM TO BE SOLVED: To provide a depilation promoter having excellent depilation promotive effect and enabling body hair removal accompanied by no pain such as mitigating the pain in removing body hair with wax coating or a tape. SOLUTION: This depilation promoter comprises an intercellular adhesion inhibitor.

公开(公告)号：JP2014058489A

公开(公告)日：2014-04-03

申请号：JP2012205939

申请日：2012-09-19

Applicant: Kao Corp ,  花王株式会社 ,  Univ Of Fukui ,  国立大学法人福井大学

Inventor： ITO NORIKO ,  NAGASAWA AZUMI ,  KOIKE KENZO ,  SAKURAI AKIHIKO

IPC: A61K8/60 ,  A61K31/7076 ,  A61P17/00 ,  A61Q7/02

Abstract: PROBLEM TO BE SOLVED: To provide a medicament or quasi drug that has excellent hair growth inhibiting action and has high safety.SOLUTION: A hair growth inhibitor contains cordycepin as an active ingredient.

Abstract translation: 要解决的问题：提供具有优异的毛发生长抑制作用并且具有高安全性的药物或准药物。解决方案：毛发生长抑制剂含有虫草素作为活性成分。

公开(公告)号：JP2009167160A

公开(公告)日：2009-07-30

申请号：JP2008185813

申请日：2008-07-17

Applicant: Kao Corp ,  花王株式会社

Inventor： NAGASAWA AZUMI ,  MORIWAKI SHIGERU ,  SAKASAI MITSUYOSHI ,  MATSUOKA MEGUMI ,  SASAJIMA MICHIYO ,  ITO NORIKO

IPC: A61K36/23 ,  A61K8/97 ,  A61P1/16 ,  A61P3/10 ,  A61P9/10 ,  A61P11/06 ,  A61P15/00 ,  A61P17/06 ,  A61P17/14 ,  A61P21/00 ,  A61P25/00 ,  A61P29/00 ,  A61P31/04 ,  A61P35/02 ,  A61P37/06 ,  A61P37/08 ,  A61P43/00 ,  A61Q7/00 ,  A61Q19/00

Abstract: PROBLEM TO BE SOLVED: To provide a novel external preparation, a hair restorer, an NFAT (nuclear factor of activated T cells) signal inhibitor, a calcineurin inhibitor, an NFAT signal inhibiting method, and a calcineurin activity inhibiting method. SOLUTION: The external preparation, the hair restorer, the NFAT signal inhibitor, and the calcineurin inhibitor comprise an extract obtained by previously washing Angelica atropurprea or the root of the plant with the use of an ethanol aqueous solution one to nine times, and thereafter extracting the ethanol washed plant or its root with the use of a 25-45 vol.% ethanol aqueous solution as an active ingredient. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 要解决的问题：提供新颖的外用制剂，毛发修复剂，NFAT（活化T细胞的核因子）信号抑制剂，钙调神经磷酸酶抑制剂，NFAT信号抑制法和钙调神经磷酸酶活性抑制法。 解决方案：外用制剂，毛发恢复剂，NFAT信号抑制剂和钙调神经磷酸酶抑制剂包含通过使用乙醇水溶液预先洗涤当归阿托普兰或植物根而获得的提取物一至九次， 然后用25-45体积％的乙醇水溶液作为活性成分萃取乙醇洗涤的植物或其根部。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2009139353A

公开(公告)日：2009-06-25

申请号：JP2007338801

申请日：2007-12-28

Applicant: Kao Corp ,  花王株式会社

Inventor： SASAJIMA MICHIYO ,  ITO NORIKO ,  MORIWAKI SHIGERU ,  FUSE CHIE

IPC: G01N33/50 ,  G01N33/15

Abstract: PROBLEM TO BE SOLVED: To provide a method for evaluating or screening a hair growth-regulating agent which utilizes a readily available animal.
SOLUTION: The method for evaluating or screening the hair growth-regulating agent is characterized by subjecting hair follicles of a pig to an organ culture in the presence of a test substance, and evaluating or selecting a substance which promotes or suppresses growth of the hair follicles.
COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 待解决的问题：提供一种评估或筛选利用易于获得的动物的毛发生长调节剂的方法。 解决方案：用于评价或筛选毛发生长调节剂的方法的特征在于，在测试物质存在下使猪的毛囊进行器官培养，并且评估或选择促进或抑制生长调节剂的生物物质 毛囊。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2008007429A

公开(公告)日：2008-01-17

申请号：JP2006177258

申请日：2006-06-27

Applicant: Kao Corp ,  花王株式会社

Inventor： FUJIMORI TAKETOSHI ,  MORIZAKI NAOKO ,  ITO NORIKO

IPC: C07K5/06 ,  A61K8/64 ,  A61K38/00 ,  A61P17/14 ,  A61Q7/00 ,  C07K1/02

Abstract: PROBLEM TO BE SOLVED: To provide a new dipeptide accelerating the formation and growth of hairs irrespective to symptoms or body qualities and effective for various alopecia, a method for producing the same and a hair tonic containing the same.
SOLUTION: This dipeptide derivative is expressed by general formula (1) [wherein, R
1 is H, hydroxy, a lower alkoxy or a lower alkyl substituted by a hydroxy lower alkoxy; and A is an amino acid residue], or its salt. The hair tonic containing the above as an active ingredient is also provided.
COPYRIGHT: (C)2008,JPO&INPIT

Abstract translation: 要解决的问题：提供一种促进头发的形成和生长的新型二肽，不论其症状或身体素质如何，并且对各种秃发有效，其制备方法和含有它们的滋养液。 解决方案：该二肽衍生物由通式（1）表示[其中，R 1是H，羟基，低级烷氧基或被羟基低级烷氧基取代的低级烷基; 和A是氨基酸残基]或其盐。 还提供含有上述作为活性成分的滋养剂。 版权所有（C）2008，JPO＆INPIT

公开(公告)号：JP2007070305A

公开(公告)日：2007-03-22

申请号：JP2005261218

申请日：2005-09-08

Applicant: Kao Corp ,  花王株式会社

Inventor： TAKIGAWA HIROBUMI ,  SASAJIMA MICHIYO ,  ITO NORIKO

IPC: A61K8/00 ,  A61Q5/00 ,  C12N1/20

Abstract: PROBLEM TO BE SOLVED: To provide a hair restore agent capable of promoting hair growth/restore and effective for alopecia of every kind regardless of symptoms or constitution. SOLUTION: This hair growth/restore agent contains an extract with an organic solvent from a culture solution of a lactic acid bacterium as an active ingredient. The lactic acid bacterium preferably belongs to the genus Lactobacillus, the genus Pediococcus, or the Leuconostoc. The lactic acid bacterium more preferably comprises Lactobacillus lactis, Pediococcus acidilactici, or Leuconostoc mesenteroides. COPYRIGHT: (C)2007,JPO&INPIT

Abstract translation: 待解决的问题：提供能够促进头发生长/恢复并且对于各种秃发有效的头发还原剂，而不管症状或体质如何。 解决方案：该毛发生长/还原剂含有来自乳酸菌的培养液作为有效成分的有机溶剂的提取物。 乳酸菌优选属于乳杆菌属，类球菌属或明串珠菌属。 更优选乳酸菌包括乳酸乳杆菌，酸性乳球菌或肠系膜梭菌。 版权所有（C）2007，JPO＆INPIT