公开(公告)号：CA3036895A1

公开(公告)日：2018-05-11

申请号：CA3036895

申请日：2017-10-23

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN

IPC: B01D35/28

Abstract: Containers for separating microcarriers from a cell culture fluid that offer a greater efficiency of filtration of cell culture fluids containing microcarriers relative to systems described in the art. The container may include a first compartment that may include a sterile collapsible bag, an inlet port providing a fluid path into the first compartment and an outlet port providing a fluid path exiting the first compartment; and a second compartment fluidly connected with the inlet port of the first compartment and including a plurality of independent or discrete microcarrier receiving regions defined by boundary walls which are partially or fully porous and having a porosity sufficient to retain the microcarriers inside the second compartment, while allowing the cell culture fluid to pass through the second compartment into the outlet port of the first compartment, where the cell culture fluid can be collected.

公开(公告)号：IN4300DEN2015A

公开(公告)日：2015-10-16

申请号：IN4300DEN2015

申请日：2015-05-20

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  PEREIRA BRIAN

IPC: B01F13/08

Abstract: A disposable container such as a deformable bag for a fluid having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing dispersing homogenizing and/or circulation of one or more ingredients contained or added to the container. The impeller assembly has a protective hood surrounding at least a portion of the moveable blades or vanes of the impeller assembly and being above at least a portion of the blades or vanes. The hood surrounds the blades or vanes and arcs over the height of the blades or vanes. The hood is shaped in a dome shape or semi spherical shape that is around and above the impeller blades and acts as a protector for the container surface against the impeller assembly both during shipping and storage as well as when in use particularly at lower liquid levels.

公开(公告)号：SG2014008593A

公开(公告)日：2014-04-28

申请号：SG2014008593

申请日：2010-02-03

Applicant: EMD MILLIPORE CORP

Inventor： DELBOS CÉCILE ,  WEISSENBACH JEAN-LOUIS ,  VIGNA JAMES ,  MORRISSEY MARTIN ,  REINBIGLER RENÉ

Abstract: A method for determining a physical value of a liquid flowing in a pipe, without contact with said liquid, said method comprising:- providing a sensor (3) for said physical value;- providing a connector (2) to insert into said pipe and comprising:- an internal passage (13) extending between two apertures (11, 12),- a flexible membrane (6) for a pressure sensor, forming a wall of said internal passage (13);- fastening said sensor (3) onto said connector (2); and- determining with said sensor (3) said physical value of said liquid flowing in a pipe;characterized in that said sensor is a temperature sensor (3) and that said step of fastening said sensor (3) onto said connector (2) is such that the sensitive part of said sensor (3) is turned towards said membrane (6).

公开(公告)号：SG164342A1

公开(公告)日：2010-09-29

申请号：SG2010010296

申请日：2010-02-18

Applicant: MILLIPORE CORP

Inventor： MORRISSEY MARTIN

Abstract: A pump is provided having a disposable bladder and disposable conduits together with check valves that control fluid flow through the bladder and conduits when the bladder is alternately compressed and expanded. The use of disposable conduits and bladder eliminates the need for hygienically regenerating the pump between uses. The pump can be utilized in a fluid delivery system such as tangential flow filtration.

公开(公告)号：CA3036895C

公开(公告)日：2021-11-16

申请号：CA3036895

申请日：2017-10-23

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN

IPC: B01D35/28

Abstract: Containers for separating microcarriers from a cell culture fluid that offer a greater efficiency of filtration of cell culture fluids containing microcarriers relative to systems described in the art. The container may include a first compartment that may include a sterile collapsible bag, an inlet port providing a fluid path into the first compartment and an outlet port providing a fluid path exiting the first compartment; and a second compartment fluidly connected with the inlet port of the first compartment and including a plurality of independent or discrete microcarrier receiving regions defined by boundary walls which are partially or fully porous and having a porosity sufficient to retain the microcarriers inside the second compartment, while allowing the cell culture fluid to pass through the second compartment into the outlet port of the first compartment, where the cell culture fluid can be collected.

公开(公告)号：SG10201708995SA

公开(公告)日：2017-11-29

申请号：SG10201708995S

申请日：2013-11-05

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  PEREIRA BRIAN

Abstract: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.

公开(公告)号：SG10201506010YA

公开(公告)日：2015-09-29

申请号：SG10201506010Y

申请日：2011-06-28

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  SCHAUER NEIL

公开(公告)号：SG10201505992UA

公开(公告)日：2015-09-29

申请号：SG10201505992U

申请日：2011-06-28

Applicant: EMD MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  SCHAUER NEIL

Abstract: A disposable flow path having a manifold system that provides pressure resistance for the disposable device. The disposable device is comprised of a first rigid plastic sheet and a second rigid plastic sheet. Each sheet has two major surfaces and a thickness between them. At least one sheet surface has flow channels formed in it. The flow channels extend away from a first major surface and beyond the normal plane of a second major surface of the sheet. The sheets are liquid tightly sealed to each other at their adjoining first major surfaces. When each sheet contains a flow channel, the flow channels are aligned and in register with each other. One or more fittings can be secured in the flow channel(s) at an edge of the two liquid tightly sealed sheets. Alternatively, tubing is placed in the channels before the sheets are secured to one another.

公开(公告)号：ES2524802T3

公开(公告)日：2014-12-12

申请号：ES10179183

申请日：2003-04-25

Applicant: EMD MILLIPORE CORP

Inventor： PROULX STEPHEN ,  ALMASIAN JOSEPH ,  RENGANATH NAREN ,  TINGLEY STEPHEN ,  MORRISSEY MARTIN

IPC: A61M39/22 ,  B67D99/00 ,  A61M39/10 ,  A61M39/16 ,  A61M39/18 ,  F16K3/26 ,  F16K15/18 ,  F16K17/40 ,  F16L37/107

Abstract: Un dispositivo de transferencia (2) para manejar fluidos de una manera estéril, que comprende: un cuerpo (4) que tiene un ánima (10) formada a través de por lo menos una parte de su interior, el cuerpo (4) tiene un primer extremo (6) conectable a un componente aguas arriba (54; 72); una abertura (62) situada aguas abajo del primer extremo (6), la abertura se puede conectar a un componente aguas abajo (56; 64; 210); un émbolo (18; 70; 98; 108) contenido dentro del ánima, el émbolo tiene un primer extremo y es movible dentro del ánima (10), por el movimiento de una leva (32) en una ranura (36) de leva que define un movimiento axial y una rotación y que limita la longitud de desplazamiento del émbolo en el ánima, entre una posición cerrada que corresponde a una posición cerrada del dispositivo en la que el primer extremo (6) del cuerpo (4) está cerrado herméticamente respecto la abertura (62) mediante un primer cierre hermético (38) y una posición abierta que corresponde a una posición abierta del dispositivo en el que el primer extremo (6) del cuerpo y la abertura se conectan con transferencia de fluidos, en donde, cuando el émbolo buzo (18; 70; 98; 108) está en la posición cerrada, el primer extremo del émbolo (18; 70; 98; 108) combinado con el primer extremo (6) del cuerpo (4) forman una superficie (46; 104) configurada para ser esterilizada con vapor de agua y una barrera estéril entre el ambiente y por lo menos una parte del interior del cuerpo (4) y el émbolo (18; 70; 98; 108); un recorrido (27; 74) de fluido que forma una conexión de fluidos a través del dispositivo entre el primer extremo (6) y la abertura (62) cuando el dispositivo está en la posición abierta; y un cierre hermético adicional que comprende dos cierres herméticos (38) o un cierre hermético lineal o de prensaestopas (90) dispuesto a lo largo del émbolo (18; 70; 98; 108) para formar un cierre hermético a líquidos entre diversas partes del émbolo (18; 70; 98; 108) y el ánima (10) cuando el émbolo (18; 70; 98; 108) está en la posición abierta para permitir la transferencia de fluido a través del recorrido de fluido al tiempo que se mantiene el estado estéril del fluido que se está transfiriendo siempre y cuando se mantenga una conexión estéril con el componente aguas arriba y el componente aguas abajo.

公开(公告)号：ES2376843T3

公开(公告)日：2012-03-20

申请号：ES09758663

申请日：2009-05-18

Applicant: MILLIPORE CORP

Inventor： MORRISSEY MARTIN ,  KELLY JAMES ,  WONG DENNIS ,  MELLO STEVE ,  WEISSENBACH JEAN-LOUISE

IPC: B67D7/00 ,  B67D99/00

Abstract: Un recipiente desechable (10) para un fluido (12) que comprende: un volumen cerrado formado por paredes flexibles, una o más entradas (20, 33) a través de las mencionadas paredes, una salida (11) a través de las mencionadas paredes, un desviador de fluidos (18, 40, 100, 108) posicionado en forma adyacente a cada una de las mencionadas entradas (20, 33) y fijadas a una superficie del desviador de fluidos (16), en donde el mencionado desviador de fluidos (18, 40, 100, 108) está adaptado para dirigir el fluido que entra en la mencionada entrada (20, 33) alejándose de la mencionada salida (11), y un supresor de vértices (14, 50) posicionado en forma adyacente a la mencionada salida (11), y fijado a una superficie interior (16) de las mencionadas paredes, en donde el mencionado supresor de vórtices (14, 50) está adaptado para dirigir el flujo inicialmente alejándose de la mencionada salida (11) y después a través de la mencionada salida (11).