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公开(公告)号:AT211303T
公开(公告)日:2002-01-15
申请号:AT91916517
申请日:1991-08-30
Applicant: PHOTOELECTRON CORP
Inventor: NOMIKOS PETER M , DINSMORE MARK T , SLISKI ALAN P
IPC: A61N5/10 , H01J35/22 , H01J35/32 , H05G1/00 , H05G1/06 , H05G1/10 , H05G1/20 , H05G1/32 , H05G1/34
Abstract: A low-level, electron beam activated source of preselected or programmable duration and intensity x-rays. The source may be fully or partially implanted into, or surface-mounted onto a desired area to affect a preselected irradiated region. In medical applications, a method of treating malignant cells, such as tumors, in vivo, utilizing the apparatus described above.
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公开(公告)号:AU4998001A
公开(公告)日:2001-08-20
申请号:AU4998001
申请日:2001-02-08
Applicant: PHOTOELECTRON CORP
Inventor: SLISKI ALAN P , HARTE KENNETH J
IPC: A61N5/10
Abstract: A radiation applicator system is structured to be mounted to a radiation source for producing a beam of radiation for treating a localized volume of tissue, such as growing blood vessels in the eye that can cause macular degeneration. The applicator system includes an applicator and, in some embodiments, an adapter. The adapter is formed for fixedly securing the applicator to a radiation source, such as a radiosurgery system which produces a predefined radiation dose profile with respect to a predefined location along the radiation producing probe. The applicator includes a shank and an applicator head. A proximate end of the applicator shank couples to the adapter. A distal end of the shank includes the applicator head, which is adapted to produce a beam of radiation. The applicator head includes a radiation shield and a beam collimator. The radiation shield selectively blocks the emitted radiation so that the applicator can be held by a surgeon during treatment. The beam collimator extends from an aperture in the shield that forms and directs a beam of radiation at a target area. Applicator systems that form different size and shape beams of radiation can be provided to accommodate a wide range of treatment volumes and for use in different treatments.
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公开(公告)号:AU4997801A
公开(公告)日:2001-08-20
申请号:AU4997801
申请日:2001-02-08
Applicant: PHOTOELECTRON CORP
Inventor: SLISKI ALAN P , HARTE KENNETH J
Abstract: A radiation applicator system is structured to be mounted to a radiation source for providing a predefined dose of radiation for treating a localized area or volume, such as the tissue surrounding the site of an excised tumor. The applicator system includes an applicator and an adapter. The adapter is formed for fixedly securing the applicator to a radiation source, such as a radiosurgery system which produces a predefined radiation dose profile with respect to a predefined location along the radiation producing probe. The applicator includes a shank and an applicator head, wherein the head is located at a distal end of the applicator shank. A proximate end of the applicator shank couples to the adapter. A distal end of the shank includes the applicator head, which is adapted for engaging and/or supporting the area or volume to be treated with a predefined does of radiation. The applicator can include a low energy radiation filter inside of the applicator head to reduce undesirable low energy radiation emissions. A biocompatible radiation shield may be coupled to the outer surface of the applicator head to block radiation emitted from a portion of the radiation probe, in order to shield an adjacent location or vital organ from any undesired radiation exposure. A plurality of applicators having applicator heads and radiation shields of different sizes and shapes can be provided to accommodate treatment sites of various sizes and shapes.
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公开(公告)号:AU703903B2
公开(公告)日:1999-04-01
申请号:AU7259896
申请日:1996-10-04
Applicant: PHOTOELECTRON CORP
Inventor: SLISKI ALAN P , DALTERIO MICHAEL , SMITH DONALD O
Abstract: A phantom apparatus for measuring the radiation dose distribution produced by a brachytherapy device used to treat a localized area with radiation. The brachytherapy device includes an insertable probe capable of producing predefined radiation dose geometries about a predefined point. The phantom apparatus includes a tank containing a medium having a radiological equivalent characteristic of the localized area to be treated. The phantom apparatus also includes a radiation sensor for measuring the radiation dose and a positioning system for moving the probe with respect to the radiation sensor. The radiation sensor is also coupled to a positioning system to orient the sensor for optimal dose measurements. The phantom apparatus includes a control system that coordinates the movements of the probe and the radiation sensor to avoid a collision. The control system moves the probe along a predefined path around radiation sensor and records the dose at predefined points along the path. In order to reduce the settling time of the sensor, the path is selected to coincide with the isodose contours of the radiation dose distribution of the probe.
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公开(公告)号:AU7915494A
公开(公告)日:1995-02-09
申请号:AU7915494
申请日:1994-12-01
Applicant: PHOTOELECTRON CORP
Inventor: NOMIKOX PETER M , DINSMORE MARK T , SLISKI ALAN P
IPC: A61N5/10 , H01J35/22 , H01J35/32 , H05G1/00 , H05G1/06 , H05G1/10 , H05G1/20 , H05G1/32 , H05G1/34 , H05G1/52
Abstract: A low-level, electron beam activated source of preselected or programmable duration and intensity x-rays. The source may be fully or partially implanted into, or surface-mounted onto a desired area to affect a preselected irradiated region. In medical applications, a method of treating malignant cells, such as tumors, in vivo, utilizing the apparatus described above.
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公开(公告)号:CA2090718A1
公开(公告)日:1992-03-06
申请号:CA2090718
申请日:1991-08-30
Applicant: PHOTOELECTRON CORP
Inventor: NOMIKOS PETER M , DINSMORE MARK T , SLISKI ALAN P
IPC: A61N5/10 , H01J35/22 , H01J35/32 , H05G1/00 , H05G1/06 , H05G1/10 , H05G1/20 , H05G1/32 , H05G1/34
Abstract: A low-level, electron beam activated source of preselected or programmable duration and intensity x-rays. The source may be fully or partially implanted into, or surface-mounted onto a desired area to affect a preselected irradiated region. In medical applications, a method of treating malignant cells, such as tumors, in vivo, utilizing the apparatus described above.
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公开(公告)号:CA2234276C
公开(公告)日:2000-05-30
申请号:CA2234276
申请日:1996-10-04
Applicant: PHOTOELECTRON CORP
Inventor: SMITH DONALD O , SLISKI ALAN P , DALTERIO MICHAEL
Abstract: This invention is a phantom apparatus (10) for measuring the radiation dose distribution produced by a brachy-therapy device used to treat a localized area with radiation. The brachy-therapy device includes an insertable probe (24) capable of producing predefined radiation dose geometries about a predefined point. The phantom apparatus (10) includes a tank (12) containing a medium having a radiological equivalent characteristic of the localized area to be treated. The phantom apparatus (10) also includes a radiation sensor (32) for measuring the radiation dose and a positioning system for moving the probe (24) with respect to the radiation sensor (32). The radiation sensor (32) is also coupled to a positioning system (50) to orient the sensor (32) for optimal dose measurements. The phantom apparatus (10) includes a control system (160) that coordinates the movements of the probe (24) and the radiation sensor (32) to avoid a collision. The control system (160) moves the probe (24) along a predefined path around radiation sensor (32) and records the dose at predefined points along the path. In order to reduce the settling time of the sensor (32), the path is selected to coincide with the isodose contours of the radiation dose distribution of the probe (24).
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公开(公告)号:AU691956B2
公开(公告)日:1998-05-28
申请号:AU3196595
申请日:1995-07-18
Applicant: PHOTOELECTRON CORP
Inventor: SLISKI ALAN P
Abstract: A system is disclosed for producing images representing radiation dose distributions in order to verify the radiation dose applied to a target area. The system uses a phantom assembly constructed of material that is the radiological equivalent of live tissue. The phantom assembly has slits where radiation sensitive film can be inserted and can include a channel for an insertable radiation generating device. The treatment dose is then applied to the phantom and the radiation sensitive film records the dose. A CCD camera microdensitometer is then used to read the exposed radiation sensitive film. The CCD camera microdensitometer includes a computer system which processes the image to remove artifacts and generates isodose contours for the radiation treatment applied. In addition, several pieces of radiation sensitive film in different planes can be exposed and processed in order to produce images representing the radiation dose distribution in three dimensions.
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公开(公告)号:AU690313B2
公开(公告)日:1998-04-23
申请号:AU3132695
申请日:1995-07-18
Applicant: PHOTOELECTRON CORP
Inventor: SLISKI ALAN P
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30.
公开(公告)号:AU684652B2
公开(公告)日:1997-12-18
申请号:AU2967695
申请日:1995-07-11
Applicant: PHOTOELECTRON CORP
Inventor: SMITH DONALD O , SLISKI ALAN P , HARTE KENNETH J
IPC: G21K5/02 , A61B1/00 , A61N5/10 , G01N23/083 , G21K5/00 , G21K5/04 , G21K5/10 , H01J35/08 , H01J35/30 , H01J35/32 , H05G1/06 , H05G1/10 , H05G1/32 , H05G1/34 , A61B6/00
Abstract: The present invention is directed to an x-ray source for irradiating a surface defining a body cavity in accordance with a predetermined dose distribution. The source comprises a housing, an elongated tubular probe, a target assembly, and an inflatable balloon. The housing encloses an electron beam source and includes elements for generating an electron beam along a beam path. The tubular probe extends along a central axis from the housing about the beam path. The target assembly extends along the central axis and is coupled to the end of the probe distal from the housing. The target assembly includes a target element is positioned in the beam path. The target element is adapted to emit x-rays in response to electrons incident thereon from the beam. The probe tip assembly and associated control electronics include elements for positioning the target element in the beam path, and is substantially x-ray transparent. The balloon is affixed to the distal end of the probe and is inflatable so that when that probe end is inserted into a body cavity, the balloon may be inflated to stretch the cavity to a known shape. Positioning the probe tip inside the inflated balloon allows delivery of a uniform, or other desired, dose of radiation to the surface defining a body cavity.
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