中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

154 records (took 0.026 seconds)

    New benzothiazolyl derivatives useful for the treatment of diabetes, cardiovascular disorders, psoriasis, dementia, osteoporosis, inflammation, obesity, anorexia, bulimia, hormono-dependent cancers and other disorders
    22.
    发明专利
    New benzothiazolyl derivatives useful for the treatment of diabetes, cardiovascular disorders, psoriasis, dementia, osteoporosis, inflammation, obesity, anorexia, bulimia, hormono-dependent cancers and other disorders 未知

    公开(公告)号：FR2830012A1

    公开(公告)日：2003-03-28

    申请号：FR0112205

    申请日：2001-09-21

    Applicant: SERVIER LAB

    Inventor： LESIEUR DANIEL ,  BLANC DELMAS ELODIE ,  BENNEJEAN CAROLINE ,  CHAVATTE PHILIPPE ,  GUILLAUMET GERALD ,  DACQUET CATHERINE ,  LEVENS NIGEL ,  BOUTIN JEAN ALBERT ,  RENARD PIERRE

    IPC: A61P3/10 ,  A61P9/10 ,  A61P17/06 ,  A61P19/10 ,  A61P35/00 ,  C07D417/12 ,  C07D417/14 ,  C07D471/04 ,  A61K31/428

    Abstract: Benzothiazolyl derivatives (I), their enantiomers, diastereoisomers, and addition salts with acids and bases. Benzothiazolyl derivatives of formula (I), their enantiomers, diastereoisomers, and addition salts with acids and bases. X = O, S, CH2 or is CH linked to R ; Y = O or S; R and R = H, alkyl, aralkyl, aryloxy, arylalkyloxy, alkoxy, OH, amino, mono- and di-alkylamino; or R +R = oxo, thioxo, or imino; A = alkylene in which one methylene group may be replaced by O, S, or NH, N-alkyl, phenylene or naphthylene; B = alkylene, alkenylene, or alkynylene; D and D' = a benzene or pyridine ring, optionally substituted by 1-3 halo, CN, NO2, R, OR, -S(O)n-R, C(Z)R, -CH(OR)-R', C(Z)OR, NRR', C(Z)NRR', -CR=N-OR, -NR-C(Z)R', -NR-C(Z)OR', and OC(Me)2-COOR; R and R' = H, alkyl, alkenyl, alkynyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, cycloalkyl, or cycloalkyl alkyl; Z = O or S; n = 0-2; R and R = H, halo, R, OR, or NRR'; or R +R = 5-6 membered ring that may contain O, N, or S; R = H, alkyl, alkenyl, alkynyl, aryl, heteroaryl, alkylcarbonyl, arylcarbonyl, or heteroaryl carbonyl, all of which may be substituted by one or more R , -CH2CHR R , -CH=CR R , halo, OH, NO2, CN, NH2 or alkoxy; R = -(CH2)t-C(=Z)Z'; t = 0-6; Z' = OR or NRR'; R and R = -C(=Z)Z' Where alkyl, alkoxy, alkylene, alkenyl, alkynyl, alkenylene and alkynylene groups have 1-6 C atoms, cycloalkyl groups have 3-8 C atoms, aryl means phenyl, naphthyl, or biphenyl, optionally partially hydrogenated, heteroaryl groups have one or two rings containing 5-10 members, optionally partially hydrogenated and containing 1-3 O, N and/or S atoms, and the aryl and heteroaryl groups may be substituted by 1-3 groups selected from alkyl, alkoxy, carboxy, formyl, amino, mono- and dialkylamino, ester, amido, NO2, CN, and OC(Me)2COOR.

Patent Agency Ranking